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Beskrivning
The subject of this book relates to protein ligands with particular structural and complexation properties. The activity of enzymes is inhibited by arresting them in the complexed state, but “naturally irreversible” complexation as in the case of immune complexation, is enhanced instead.
Dr Irena Roterman-Konieczna – professor of bioinformatics heads the bioinformatics group at the Jagiellonian University – Medical College and the Faculty of Physics, Astronomy and Applied Computer Science, Poland. Her background is the theoretical chemistry and her research focuses on bioinformatics with a special focus on protein structure prediction. Involved also in education of medical students and students of computer science developing different forms of simulations in medicine.
Innehållsförteckning
Supramolecular Protein Ligands – Unexplored Teritory Of Potential Pharmacological Activity.- Supramolecular Congo Red As Specific Ligand Of Antibodies Engaged In Immune Complex.- Protein Conditioning For Binding Congo Red And Other Supramolecular Ligands.- Metal Ions Introduced To Proteins By Supramolecular Ligands.- Possible Mechanism Of Amyloidogenesis Of V Domains.- Supramolecular Structures As Carrier Systems Enabling The Use Of Metal Ions In Antibacterial Therapy.- Congo Red Interactions With Single-Walled Carbon Nanotubes.