Advances in Eicosanoid Research

Häftad, Engelska, 2012

Del i serien Ernst Schering Foundation Symposium Proceedings

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Beskrivning

Over the last few years, we have witnessed tremendous progress in the field of eicosanoids and their therapeutic applications. New molecules and me diators have been identified, new enzymes and pathways elucidated and new therapeutic approaches have emerged.

Produktinformation

Utgivningsdatum:2012-12-06
Mått:148 x 210 x undefined mm
Vikt:316 g
Format:Häftad
Språk:Engelska
Serie:Ernst Schering Foundation Symposium Proceedings
Antal sidor:225
Förlag:Springer-Verlag Berlin and Heidelberg GmbH & Co. KG
ISBN:9783662040492

Utforska kategorier

Biokemi inom Naturvetenskap och teknik
Onkologi inom Medicin
Biokemisk teknik inom Naturvetenskap och teknik

Innehållsförteckning

1 The Mechanism of Action of Anti-Inflammatory Drugs.- 2 Human Group-V Phospholipase-A2 Expression in Pichia pastoris and Its Role in Eicosanoid Generation.- 3 Fatty-Acid Substrate Interactions with Cyclooxygenases.- 4 Structure, Function and Inhibition of Cyclooxygenases.- 5 Leukotriene-A4 Hydrolase: Probing the Active Sites and Catalytic Mechanisms by Site-Directed Mutagenesis.- 6 The Regulation of Cyclooxygenase-1 and -2 in Knockout Cells and Cyclooxygenase and Fever in Knockout Mice.- 7 Leukotriene-B4 Receptor and Signal Transduction.- 8 Lipoxins, Aspirin-Triggered 15-epi-Lipoxin Stable Analogs and Their Receptors in Anti-Inflammation: a Window for Therapeutic Opportunity.- 9 Lipoxin-Stable Analogs: Potential Therapeutic Downregulators of Intestinal Inflammation.- 10 The Role of Eicosanoids in Tumor Growth and Metastasis.- Previous Volumes Published in this Series.