Coxiella burnetii: Recent Advances and New Perspectives in Research of the Q Fever Bacterium

Inbunden, Engelska, 2012

Del i serien Advances in Experimental Medicine and Biology

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Beskrivning

burnetii resists the degradative functions of this vacuole, and the host cell functions coopted for successful parasitism, are central to understanding Q fever pathogenesis. Several chapters survey immune functions that control or potentially exacerbate Coxiella infection and delve into correlates of protective immunity elicited by vaccination.

Produktinformation

Utgivningsdatum:2012-06-22
Mått:155 x 235 x 27 mm
Vikt:720 g
Format:Inbunden
Språk:Engelska
Serie:Advances in Experimental Medicine and Biology
Antal sidor:406
Förlag:Springer
ISBN:9789400743144

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Innehållsförteckning

1. History and prospects of Coxiella burnetii research. - 2. Phylogenetic diversity, virulence and comparative genomics. - 3. Defense mechanisms against oxidative stress in Coxiella burnetii: Adaptation to a unique intracellular niche. - 4. Lipopolysaccharide of Coxiella burnetii. - 5. Components of protective immunity. - 6. Proteome of Coxiella burnetii. - 7. Coxiella subversion of intracellular host signaling. - 8. The Coxiella burnetii parasitophorous vacuole. - 9. Coxiella burnetii secretion systems. - 10. Role of lipids in Coxiella burnetii infection. - 11. Axenic growth of Coxiella burnetii. - 12. Developmental biology of Coxiella burnetii. - 13. Genetic manipulation of Coxiella burnetii. - 14. Role of innate and adaptive immunity in the control of Q fever. - 15. Immune response and Coxiella burnetii invasion. - 16. Antigenic analysis for vaccines and diagnostics. - 17. Epidemic Q Fever in humans in the Netherlands. - 18. Coxiella-like endosymbionts. -19. Molecular typing of Coxiella burnetii (Q fever).