GAPDH: Biological Properties and Diversity

AvNorbert W. Seidler

Inbunden, Engelska, 2012

Del 985 i serien Advances in Experimental Medicine and Biology

2 271 kr

Beställningsvara. Skickas inom 10-15 vardagar. Fri frakt över 249 kr.

Fler format och utgåvor

E-bok

2 127 kr

Häftad

1 911 kr

Beskrivning

The book represents a comprehensive review and synthesis of the biomedical literature that spans over a half-century on a single protein called glyceraldehyde 3-phosphate dehydrogenase (or, GAPDH). Due to the protein’s involvement in a vast array of cellular activities, GAPDH is of interest to the cell biologist, immunologist, virologist, biochemist etc. The protein has a significant role in fertility, cancer and neurodegeneration, suggesting that this book can be a vital resource for drug development. GAPDH function may provide insight into anesthesia. Furthermore, GAPDH is highly conserved meaning that the protein found in microorganisms, such as pathogens, remained relatively unchanged in evolution. Pathogens use GAPDH as a virulence factor, offering a unique challenge in developing anti-microbial agents that target this protein. To the evolutionary biologist, a book on the multi-functionality of GAPDH provides a focal point for a cogent discussion on the very origin of life.

Produktinformation

Utgivningsdatum:2012-07-31
Mått:178 x 254 x 22 mm
Vikt:787 g
Format:Inbunden
Språk:Engelska
Serie:Advances in Experimental Medicine and Biology
Antal sidor:295
Upplaga:2013
Förlag:Springer
ISBN:9789400747159

Utforska kategorier

Cellbiologi inom Naturvetenskap och teknik
Medicinsk utrustning och medicinska tekniker inom Medicin
Biomedicinsk teknik inom Medicin

Recensioner i media

From the book reviews: "The biochemical, physiological, and metabolic roles of GAPDH is discussed starting with the cell membrane and ionic mechanisms of glycolysis, energetics, and the TCA cycle. This is a book which should explore in greater detail the effects on blood brain barrier and CNS metabolism. I do however, highly recommend this book to physiologists and biochemists. Graduate students and postdocs will probably find this a very good discussion of GAPDH." (Joseph J. Grenier, Amazon.com, August, 2014)

Innehållsförteckning

1. Basic Biology of GAPDH. - 2. GAPDH and Intermediary Metabolism. - 3. Compartmentation of GAPDH. - 4. Functional Diversity. - 5. GAPDH, as a Virulence Factor. - 6. Target for Diverse Chemical Modifications. - 7. Dynamic Oligomeric Properties. - 8. Multiple Binding Partners. - 9. GAPDH in Anesthesia.

Mer från samma serie

Frontiers in Brain Repair

Rahul Jandial

Inbunden, 2010

1 705 kr

Oxygen Transport to Tissue XXXIV

William J. Welch, Fredrik Palm, Duane F. Bruley, David K. Harrison

Inbunden, 2012

2 267 kr

Del 858

Pulmonary Function

Mieczyslaw Pokorski

Häftad, 2016

1 139 kr

Biology of Taurine

Ryan J. Huxtable, F. Franconi, A. Giotti

Inbunden, 1987

2 205 kr

Molecular Immunology of Complex Carbohydrates

Albert M. Wu, L. Garry Adams

Inbunden, 1988

1 106 kr

Mechanisms of Physical and Emotional Stress

George P. Chrousos, D. Lynn Loriaux, Philip W. Gold

Inbunden, 1989

2 271 kr

Del 281

Fibrinogen, Thrombosis, Coagulation and Fibrinolysis

Chung Yuan Liu, Chung Yuan Liu, Shu Chien

Inbunden, 1991

912 kr

Molecular and Cellular Biology Prostate Cancer

Symposium on Molecular and Cellular Biol, James P. Karr, etc.

Inbunden, 1991

912 kr

Nutritional and Toxicological Consequences of Food Processing

Mendel Friedman

Inbunden, 1991

2 271 kr

Recombinant Technology in Haemostasis and Thrombosis

Leon W. Hoyer, Leon Ed Hoyer, W.N. Drohan, Leon W. Hoyer, W N Drohan, Leon W Hoyer

Inbunden, 1991

912 kr

Du kanske också är intresserad av

Del 985