Human Epigenomics

AvCarsten Carlberg,Ferdinand Molnár

Häftad, Engelska, 2019

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Beskrivning

This was the start of the field of epigenomics, the relation of which to human health and disease is discussed in this textbook. This book aims to summarize, in a condensed form, the role of epigenomics in defining chromatin states that are representative of active genes (euchromatin) and repressed genes (heterochromatin).

Produktinformation

Utgivningsdatum:2019-01-30
Mått:155 x 235 x 16 mm
Vikt:376 g
Format:Häftad
Språk:Engelska
Antal sidor:223
Förlag:Springer Verlag, Singapore
ISBN:9789811356605

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Mer om författaren

Prof. Carsten Carlberg: Professor for biochemistry at the School of Medicine, Institute of Biomedicine at the University of Eastern Finland. The main research interests of Prof. Carlberg are (epi)genomics of nuclear receptors and their ligands with special focus on vitamin D. So far he published more than 200 papers (H-index 54). Since 2001 he is lecturing yearly courses on epigenetics and gene regulation, which are the basis of this textbook. Together with Dr. Molnár he also published the Springer textbooks "Mechanisms of gene regulation" and “Nutrigenomics”.Dr. Ferdinand Molnár: Project researcher at the School of Medicine, Institute of Biomedicine at the University of Eastern Finland. The main research interests of Dr. Molnár are the molecular structure of nuclear receptor proteins and their natural and synthetic ligands, on which he published more than 27 papers (H-index 17). Together with Prof. Carlberg he published the Springer textbooks "Mechanisms of gene regulation" and “Nutrigenomics”.

Innehållsförteckning

What is epigenomics?.- Methods and applications of epigenomics.- The structure of chromatin.- DNA methylation.- The histone code.- Chromatin modifiers.- Chromatin remodelers and organizers.- Embryogenesis and cellular differentiation.- Population epigenomics and aging.- Cancer epigenomics.- Neuroepigenetics.- Epigenomics of immune function.- Nutritional epigenomics.