Glycosignals in Cancer

Molecular Assembly and Recognition

Inbunden, Engelska, 2023

1 630 kr

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Beskrivning

This book, now in an extensively revised second edition, provides a comprehensive summary of the latest knowledge regarding glycosignals and a thorough analysis of their involvement in not only cancers but also other refractory conditions such as chronic inflammatory disorders.

Produktinformation

Utgivningsdatum:2023-03-21
Mått:155 x 235 x 18 mm
Vikt:580 g
Format:Inbunden
Språk:Engelska
Antal sidor:238
Upplaga:2
Förlag:Springer Verlag, Singapore
ISBN:9789811977312

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Mer om författaren

Koichi FurukawaCollege of Life and Health Sciences, Chubu University, JapanMinoru FukudaCancer Research Center, Standford-Burnham Medical Research Institute La Jolla, CA, USA

Innehållsförteckning

Part I. Search for novel tumor epitopes related to carbohydrates.- Chapter 1.1. The ganglioside structures: chemistry and biochemistry.- Chapter 1.2. Fucosylated proteins as cancer biomarkers.- Part II. Assembly of glycoconjugates.- Chapter 2.1. Siglec-7 and synthetic sialylpolymer.- Chapter 2.2. Role of Sialyl-Tn antigen in Cancer Metastasis.- Chapter 2.3. Insights into the Role of Chondroitin Sulfate in Cancer.- Part III. Signaling pathways modulated by glycosylation.- Chapter 3.1. Significance of FUT8in pancreatic cancer and others.- Chapter 3.2. Effects of Bullfrog sialic acid-binding lectin in cancer cells.- Part IV. Interaction between carbohydrate and carbohydrate-recognizing molecules.- Chapter 4.1. Opposite functions of mono- and disialylated glycosphingolipids on the membrane of cancer cells.- Chapter 4.2. Tumor progression through interaction of mucins with lectins and subsequent signal transduction.- Part V. Clinical trials targeting glycosignals.- Chapter 5.1. Immunotherapy of Neuroblastoma Targeting GD2 and Beyond.