Tau Biology

AvAkihiko Takashima,Benjamin Wolozin

Inbunden, Engelska, 2020

Del 1184 i serien Advances in Experimental Medicine and Biology

2 505 kr

Beställningsvara. Skickas inom 10-15 vardagar. Fri frakt över 249 kr.

Beskrivning

This book presents essential studies and cutting-edge research results on tau, which is attracting increasing interest as a target for the treatment of Alzheimer's disease. Tau is well known as a microtubule-associated protein that is predominantly localized in the axons of neurons.  In various forms of brain disease, neuronal loss occurs, with deposition of hyperphosphorylated tau in the remaining neurons.  Important questions remain regarding the way in which tau forms hyperphosphorylated and fibrillar deposits in neurons, and whether tau aggregation represents the toxic pathway leading to neuronal death.  With the help of new technologies, researchers are now solving these long-standing questions.  In this book, readers will find the latest expert knowledge on all aspects of tau biology, including the structure and role of the tau molecule, tau localization and function, the pathology, drivers, and markers of tauopathies, tau aggregation, and treatments targeting tau. Tau Biology will be an invaluable source of information and fresh ideas for those involved in the development of more effective therapies and for all who seek a better understanding of the biology of the aging brain.

Produktinformation

Utforska kategorier

Mer om författaren

Innehållsförteckning

Hoppa över listan

Du kanske också är intresserad av

Del 1184

Tau Biology

Akihiko Takashima, Benjamin Wolozin, Luc Buee

Häftad

2 505 kr

Del 1184

One-parameter Semigroups of Positive Operators

Wolfgang Arendt, Annette Grabosch, Günther Greiner, Ulrich Groh, Heinrich P. Lotz, Ulrich Moustakas, Rainer Nagel, Frank Neubrander, Ulf Schlotterbeck, Rainer Nagel

Häftad

534 kr

  • Nyhet

Kött

David Szalay

Inbunden

259 kr