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The renowned one-stop guide to the entire field of clinical endocrinology and its scientific underpinnings – now in full color

270+ full-color photographs and illustrations!

A Doody''s Core Title for 2011!

4 STAR DOODY''S REVIEW!"This is an excellent overview of the basic physiology and clinical aspects of endocrinology for trainees. The size of the book and the well-written text, supported by visual aids, make this a convenient book to read and develop a beginning foundation in endocrinology."--Doody''s Review Service

Greenspan’s Basic & Clinical Endocrinology, 9e delivers a succinct, leading-edge overview of the underlying molecular biology of the endocrine system and the latest perspectives on the diagnosis and treatment of specific diseases and disorders. Featuring an enhanced design that includes hundreds of full-color illustrations and clinical photographs, Greenspan’s is a true must-have during traditional or integrated courses in endocrinology, endocrinology rotation, or for exam prep in internal medicine and endocrinology.

Greenspan’s provides clinically relevant coverage of metabolic bone disease, pancreatic hormones and diabetes mellitus, hypoglycemia, obesity, geriatric endocrinology, and many other diseases and disorders. Supporting this essential material is a handy appendix of normal hormone reference ranges.

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The essential pharmacotherapy data you need for clinical practice and board preparation – in one carry-anywhere guide

A Doody''s Core Title for 2017!

Pharmacotherapy Handbook provides the critical information you need to make drug therapy decisions for more than 140 diseases and disorders commonly encountered in a clinical setting. Featuring a convenient alphabetized presentation, this handy guide utilizes text, tables, figures, and treatment algorithms to make important drug data readily accessible and easily understood.

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Learn the key concepts of basic and clinical neurology with a unique practice-oriented approach

For more than two decades, Clinical Neurology has helped students, residents, and clinicians understand the link between basic neuroscience and current approaches in diagnosis and treatment. Distinguished by its practice-oriented approach to neurology based on the patients’ presenting symptoms, this full-color resource delivers the clearest and most efficient introduction to the field available today.

Every chapter of this edition has been updated, and in many cases nearly completely rewritten to maintain the emphasis on the practical aspects of neurology while discussing the scientific underpinnings. The Ninth Edition is also enhanced by:

There is no better introduction to neurology as practiced on the wards and in an outpatient setting than this time-tested classic.

Avery's Diseases of the Newborn, edited by Christine A. Gleason and Sherin U. Devaskar, is a practical, clinical reference for diagnosing and managing of all the important diseases affecting newborns. Thoroughly revised by a team of new editors, this edition provides new perspectives and updated coverage of genetics, nutrition, respiratory conditions, MRSA, neonatal pain, cardiovascular fetal interventions, care of the late preterm infant, and more. You can also access the fully searchable text and downloadable images online at www.expertconsult.com, making this authoritative reference ideal as a clinical resource or subspecialty review tool.

This foundational work comprehensively examines the current state of the genetics, genomics and brain circuitry of psychiatric and neurological disorders. It consolidates discoveries of specific genes and genomic regions associated with these conditions, the genetic and anatomic architecture of these syndromes, and addresses how recent advances in genomics are leading to a reappraisal of the biology underlying clinical neuroscience. In doing so, it critically examines the promise and limitations of these discoveries toward treatment, and to the interdisciplinary nature of understanding brain and behavior. Coverage includes new discoveries regarding autism, epilepsy, intellectual disability, dementias, movement disorders, language impairment, disorders of attention, schizophrenia, and bipolar disorder. Genomics, Circuits, and Pathways in Clinical Neuropsychiatry focuses on key concepts, challenges, findings, and methods in genetics, genomics, molecular pathways, brain circuitry, and related neurobiology of neurologic and psychiatric disorders.

Advances in Alzheimer's disease (AD) research have been challenging and without major breakthroughs in understanding its pathological basis. The reigning hypothesis suggests AD is the result of extracellular amyloid deposition that seed to form amyloid plaques, which then grow and kill neighboring neurons. However, there are several inconsistencies with this hypothesis, not to mention the inability to show clinical benefit in several failed clinical trials by pharmaceuticals (i.e., from Pfizer, Eli Lilly, etc.), and it is in the field's best interest to explore and test multiple hypotheses for pathology rather than drive the majority of research on this single amyloid theory. Reviewing many scientifically peer-reviewed publications, this book describes the "Inside-Out" hypothesis on how amyloid escapes the circulatory system through a dysfunctional blood-brain barrier to bind to the alpha 7 nicotinic acetylcholine receptor on pyramidal neurons. Over time, excessive amounts of amyloid appear to be internalized, resulting in neuron death and lysis. This simple mechanism readily explains plaque composition, size, shape, and location. Based on the current direction of research in the field, this hypothesis appears years from any research and development.

Immunopotentiators in Modern Vaccines, Second Edition, provides in-depth insights and overviews of the most successful adjuvants, those that have been included in licensed products, also covering the most promising technologies that have emerged in recent years. In contrast to existing books on the subject, the chapters here provide summaries of key data on the mechanisms of action of the individual vaccine adjuvants.

In addition, the book covers key aspects of how the technologies might be further developed and what might be their limitations, while also giving an overview of what made the most advanced adjuvant technologies successful.