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87 produkter
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Opportunities in Chemistry is based on the contributions of hundreds of American chemists in academia and industry and should be taken as the best available consensus of the chemical community regarding its intellectual frontiers and the economic opportunities that lie beyond them," says Science. This volume addresses the direction in which today's chemical research is heading, including recent developments, technological applications, and the ways advances in chemistry can be used to improve the human condition. In addition, the book examines economic and political implications of chemical research and lists resources for basic research and education in the chemical sciences.
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This book captures the messages from a workshop that brought together research managers from government, industry, and academia to review and discuss the mechanisms that have been proposed or used to assess the value of chemical research. The workshop focused on the assessment procedures that have been or will be established within the various organizations that carry out or fund research activities, with particular attention to the Government Performance and Results Act (GPRA). The book presents approaches and ideas from leaders in each area that were intended to identify new and useful ways of assessing the value and potential impact of research activities.
Laboratory Design, Construction, and Renovation
Participants, Process, and Product
Häftad, Engelska, 2000
1 278 kr
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Laboratory facilities are complex, technically sophisticated, and mechanically intensive structures that are expensive to build and to maintain. Hundreds of decisions must be made before and during new construction or renovation that will determine how successfully the facility will function when completed and how successfully it can be maintained once put into service. This book provides guidance on effective approaches for building laboratory facilities in the chemical and biochemical sciences. It contains both basic and laboratory-specific information addressed to the user community-the scientists and administrators who contract with design and construction experts. The book will also be important to the design and construction communities-the architects, laboratory designers, and engineers who will design the facility and the construction personnel who will build it-to help them communicate with the scientific community for whom they build laboratory facilities.
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The Committee on Electrometallurgical Techniques for DOE Spent Fuel Treatment was formed in September 1994 in response to a request made to the National Research Council (NRC) by the U.S. Department of Energy DOE. DOE requested an evaluation of electrometallurgical processing technology proposed by Argonne National Laboratory (ANL) for the treatment of DOE spent nuclear fuel. Electrometallurgical treatment of spent reactor fuel involves a set of operations designed to remove the remaining uranium metal and to incorporate the radioactive nuclides into well defined and reproducible waste streams. Over the course of the committee's operating life, this charge has remained constant. Within the framework of this overall charge, the scope of the committee's work--as defined by its statement of task--has evolved in response to further requests from DOE, as well as technical accomplishments and regulatory and legal considerations. As part of its task, the committee has provided periodic assessments of ANL's R&D program on the electrometallurgical technology.Electrometallurgical Techniques for DOE Spent Fuel Treatment assesses the viability of electrometallurgical technology for treating DOE spent nuclear fuel and monitors the scientific and technical progress of the ANL program on electrometallurgical technology, specifically within the context of ANL's demonstration project on electrometallurgical treatment of EBR-II SNF. This report evaluates ANL's performance relative to the success criteria for the demonstration project, which have served as the basis for judging the efficacy of using electrometallurgical technology for the treatment of EBR-II spent nuclear fuel. It also addresses post-demonstration activities related to ANL's electrometallurgical demonstration project, and makes related recommendations in this area.
Graduate Education in the Chemical Sciences
Issues for the 21st Century: Report of a Workshop
Häftad, Engelska, 2000
1 275 kr
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Graduate Education in the Chemical Sciences is a summary of the December 1999 workshop, "Graduate Education in the Chemical Sciences: Issues for the 21st Century,"This workshop discussed the various features of graduate education in chemical science and technology. Using case histories and their individual experiences, speakers examined the current status of graduate education in the chemical sciences, identified problems and opportunities, and discussed possible strategies for improving the system. The discussion was oriented toward the goal of generating graduates who are well prepared to advance the chemical sciences in academia, government, and industry in the next 5 to 10 years.
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The Second World War introduced the world to nuclear weapons and their consequences. Behind the scene of these nuclear weapons and an aspect of their consequences is radioactive waste. Radioactive waste has varying degrees of harmfulness and poses a problem when it comes to storage and disposal. Radioactive waste is usually kept below ground in varying containers, which depend on how radioactive the waste it. High-level radioactive waste (HLW) can be stored in underground carbon-steel tanks. However, radioactive waste must also be further immobilized to ensure our safety. There are several sites in the United States where high-level radioactive waste (HLW) are stored; including the Savannah River Site (SRS), established in 1950 to produce plutonium and tritium isotopes for defense purposes. In order to further immobilize the radioactive waste at this site an in-tank precipitation (ITP) process is utilized. Through this method, the sludge portion of the tank wastes is being removed and immobilized in borosilicate glass for eventual disposal in a geological repository. As a result, a highly alkaline salt, present in both liquid and solid forms, is produced.The salt contains cesium, strontium, actinides such as plutonium and neptunium, and other radionuclides. But is this the best method? The National Research Council (NRC) has empanelled a committee, at the request of the U.S. Department of Energy (DOE), to provide an independent technical review of alternatives to the discontinued in-tank precipitation (ITP) process for treating the HLW stored in tanks at the SRS. Alternatives for High-Level Waste Salt Processing at the Savannah RIver Site summarizes the finding of the committee which sought to answer 4 questions including: "Was an appropriately comprehensive set of cesium partitioning alternatives identified and are there other alternatives that should be explored?" and "Are there significant barriers to the implementation of any of the preferred alternatives, taking into account their state of development and their ability to be integrated into the existing SRS HLW system?"
Women in the Chemical Workforce
A Workshop Report to the Chemical Sciences Roundtable
Häftad, Engelska, 2000
1 363 kr
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For a period of history no women worked outside the home. Bust as years have gone by and society has changed, Women are working varying jobs every day. They are, however, underrepresented in some sectors of jobs. This includes women in the engineering and science fields. To matters worse, women do not ascend the career ladder as fast as or as far as men do. The impact of this and related problems for science, the academic enterprise, the U.S. economy, and global economic competitiveness have been recently examined. The Chemical Sciences Roundtable evaluate that the demographics of the workforce and the implications for science and society vary, depending on the field of science or engineering. The roundtable has organized a workshop, "Women in the Chemical Workforce," to address issues pertinent to the chemical and chemical engineering workforce as a whole, with an emphasis on the advancement of women.Women in the Chemical Workforce: A Workshop Report to the Chemical Sciences Roundtable includes reports regarding the workshop's three sessions-Context and Overview, Opportunities for Change, and Conditions for Success-as well as presentations by invited speakers, discussions within breakout groups, oral reports from each group.
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Considerable international concerns exist about global climate change and its relationship to the growing use of fossil fuels. Carbon dioxide is released by chemical reactions that are employed to extract energy from fuels, and any regulatory policy limiting the amount of CO2 that could be released from sequestered sources or from energy-generating reactions will require substantial involvement of the chemical sciences and technology R&D community. Much of the public debate has been focused on the question of whether global climate change is occurring and, if so, whether it is anthropogenic, but these questions were outside the scope of the workshop, which instead focused on the question of how to respond to a possible national policy of carbon management. Previous discussion of the latter topic has focused on technological, economic, and ecological aspects and on earth science challenges, but the fundamental science has received little attention.This workshop was designed to gather information that could inform the Chemical Sciences Roundtable in its discussions of possible roles that the chemical sciences community might play in identifying and addressing underlying chemical questions.
Research and Development on a Salt Processing Alternative for High-Level Waste at the Savannah River Site
Häftad, Engelska, 2001
477 kr
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The U.S. Department of Energy (DOE) is nearing a decision on how to process 30 million gallons of high-level radioactive waste salt solutions at the Savannah River Site in South Carolina to remove strontium, actinides, and cesium for immobilization in glass and eventual shipment to a geologic repository. The department is sponsoring research and development (R&D) work on four alternative processes and plans to use the results to make a downselection decision in a June 2001 time frame. The DOE requested that the National Research Council help inform this decision by addressing the following charge: 1. evaluate the adequacy of the criteria that will be used by the department to select from among the candidate processes under consideration; 2. evaluate the progress and results of the research and development work that is being undertaken on these candidate processes; and 3. assess whether the technical uncertainties have been sufficiently resolved to proceed with downsizing the list of candidate processes. Responses to the last two points are provided in this report.Research and Development on a Salt Processing Alternative for High-Level Waste at the Savannah River Site focuses exclusively on the technical issues related to the candidate processes for radionuclide removal from high-level waste salt solutions at SRS. The committee's interim report served as a response to the first point of this charge, and may be read in Appendix B. In that report, the committee found that DOE's proposed criteria are an acceptable basis for selecting among the candidate processes under consideration, but that the criteria should not be implemented in a way that relies on a single numerical "total score."
316 kr
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People spend the vast majority of their time inside their homes and other indoor environments where they are exposed to a wide range of chemicals from building materials, furnishings, occupants, cooking, consumer products, and other sources. Despite research to date, very little is known about how exposures to indoor chemicals across complex chemical phases and pathways affect human health. The COVID-19 pandemic has only increased public awareness of indoor environments and shed light on the many outstanding questions about how best to manage chemicals indoors. This report identifies gaps in current research and understanding of indoor chemistry and new approaches that can be applied to measure, manage, and limit chemical exposures. Why Indoor Chemistry Matters calls for further research about the chemical transformations that can occur indoors, pathways and timing of indoor chemical exposure, and the cumulative and long-term impacts of exposure on human health. Research priorities should consider factors that contribute to measurable environmental health disparities that affect vulnerable populations, such as the age, location, and condition of buildings that can alter exposures to indoor chemicals.
Beyond the Molecular Frontier
Challenges for Chemistry and Chemical Engineering
Häftad, Engelska, 2003
666 kr
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Chemistry and chemical engineering have changed significantly in the last decade. They have broadened their scopea "into biology, nanotechnology, materials science, computation, and advanced methods of process systems engineering and controla "so much that the programs in most chemistry and chemical engineering departments now barely resemble the classical notion of chemistry. Beyond the Molecular Frontier brings together research, discovery, and invention across the entire spectrum of the chemical sciencesa "from fundamental, molecular-level chemistry to large-scale chemical processing technology. This reflects the way the field has evolved, the synergy at universities between research and education in chemistry and chemical engineering, and the way chemists and chemical engineers work together in industry. The astonishing developments in science and engineering during the 20th century have made it possible to dream of new goals that might previously have been considered unthinkable.This book identifies the key opportunities and challenges for the chemical sciences, from basic research to societal needs and from terrorism defense to environmental protection, and it looks at the ways in which chemists and chemical engineers can work together to contribute to an improved future.
National Security and Homeland Defense
Challenges for the Chemical Sciences in the 21st Century
Häftad, Engelska, 2002
603 kr
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This is the first report of seven in the Challenges for the Chemical Sciences in the 21st Century series. The report is based on discussions and presentations at a workshop, and is intended to help scientists and funding agencies set short- and long-term research agendas. It focuses on the challenges for chemists and chemical engineers with respect to threat reduction, preparation, situational awareness, and threat neutralization and remediation
Materials Science and Technology
Challenges for the Chemical Sciences in the 21st Century
Häftad, Engelska, 2003
477 kr
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The report assesses the current state of chemistry and chemical engineering at the interface with materials science and identifies challenges for research. Recent advances are blurring the distinction between chemistry and materials science and are enabling the creation of new materials that, to date, have only been predicted by theory. These advances include a greater ability to construct materials from molecular components, to design materials for a desired function, to understand molecular "self-assembly, and to improve processes by which the material is "engineered" into the final product.
Minorities in the Chemical Workforce
Diversity Models that Work: A Workshop Report to the Chemical Sciences Roundtable
Häftad, Engelska, 2003
614 kr
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This report to the Chemical Sciences Roundtable presents a collection of contributed papers that report success stories for increasing diversity. The report provides background information on the value of diversity in the undergraduate environment, and the success stories address both undergraduate and graduate chemistry programs as well as chemical industry.
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The report assesses the current state of chemistry and chemical engineering at the interface with environmental science, examines its interactions with related areas of science and technology, and identifies challenges and opportunities for research. The report also identifies important contributions that have been made by the chemical sciences toward solving environmental problems, and emphasizes the opportunities for chemists and chemical engineers to make future contributions toward understanding and improving the environment.
477 kr
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The report assesses the current state of chemistry and chemical engineering within the context of drug discovery, disease diagnosis, and disease prevention. Also addressed are chemical and chemical engineering challenges in pharmaceutical synthesis, delivery, and manufacture.
Information and Communications
Challenges for the Chemical Sciences in the 21st Century
Häftad, Engelska, 2003
751 kr
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Since publication of the National Research Council (NRC) reports on chemistry in 1985 and chemical engineering in 1988,1,2 dramatic advances in information technology (IT) have totally changed these communities. During this period, the chemical enterprise and information technology have enjoyed both a remarkably productive and mutually supportive set of advances. These synergies sparked unprecedented growth in the capability and productivity of both fields including the definition of entirely new areas of the chemical enterprise. The chemical enterprise provided information technology with device fabrication processes, new materials, data, models, methods, and (most importantly) people. In turn, information technology provided chemical science and technology with truly remarkable and revolutionary resources for computations, communications, and data management. Indeed, computation has become the strong third component of the chemical science research and development effort, joining experiment and theory. Sustained mutual growth and interdependence of the chemical and information communities should take account of several unique aspects of the chemical sciences.These include extensive and complex databases that characterize the chemical disciplines; the importance of multiscale simulations that range from molecules to technological processes; the global economic impact of the chemical industry; and the industry's major influence on the nation's health, environment, security, and economic well-being. In planning the future of the chemical sciences and technology, it is crucial to recognize the benefits already derived from advances in information technology as well as to point the way to future benefits that will be derived.
Reducing the Time from Basic Research to Innovation in the Chemical Sciences
A Workshop Report to the Chemical Sciences Roundtable
Häftad, Engelska, 2003
637 kr
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Innovation, the process by which fundamental research becomes a commercial product, is increasingly important in the chemical sciences and is changing the nature of research and development efforts in the United States. The workshop was held in response to requests to speed the R&D process and to rapidly evolve the patterns of interaction among industry, academe, and national laboratories. The report contains the authors' written version of the workshop presentations along with audience reaction.
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The report provides an independent assessment of suitable test protocols that might be useful and reliable for the testing and evaluation of standoff chemical agent detectors. The report proposes two testing protocols, one for passive detectors and one for active detectors, to help ensure the reliable detection of a release of chemical warfare agents. The report determined that testing these detectors by release of chemical warfare agents into the atmosphere would not provide additional useful information on the effectiveness of these detectors than would a rigorous testing protocol using chemical agents in the laboratory combined with atmospheric release of simulated chemical warfare agents.
Energy and Transportation
Challenges for the Chemical Sciences in the 21st Century
Häftad, Engelska, 2003
608 kr
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This book, also based on a workshop, assesses the current state of chemistry and chemical engineering at the interface with novel and existing forms of energy and transportation systems. The book also identifies challenges for the chemical sciences in helping to meet the increased demand for more energy, and opportunities for research in energy technologies and in the development of transportation vehicles.
Innovations in Pharmaceutical Manufacturing on the Horizon
Technical Challenges, Regulatory Issues, and Recommendations
Häftad, Engelska, 2021
585 kr
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In 2002, the U.S. Food and Drug Administration (FDA) launched the Pharmaceutical Quality for the 21st Century Initiative to encourage adoption of innovative technologies that would lead to an agile, flexible pharmaceutical manufacturing sector. The goal was to encourage a transition to manufacturing processes and approaches that could produce high-quality drugs reliably without extensive regulatory oversight. Much progress has been made toward that goal as the industry has developed and advanced new technologies, but more progress is required as recent natural disasters and the coronavirus pandemic have revealed vulnerabilities in supply chains and highlighted the need to modernize pharmaceutical manufacturing further.At the request of the FDA Center for Drug Evaluation and Research (CDER), Innovations in Pharmaceutical Manufacturing on the Horizon identifies emerging technologies - such as product technologies, manufacturing processes, control and testing strategies, and platform technologies - that have the potential to advance pharmaceutical quality and modernize pharmaceutical manufacturing for products regulated by CDER. This report describes many innovations to modernize the manufacture of drug substances and drug products, to advance new control approaches, and to develop integrated, flexible, and distributed manufacturing networks within 5-10 years.
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Since the 1960s, testimony by representatives of the Federal Bureau of Investigation in thousands of criminal cases has relied on evidence from Compositional Analysis of Bullet Lead (CABL), a forensic technique that compares the elemental composition of bullets found at a crime scene to the elemental composition of bullets found in a suspecta (TM)s possession. Different from ballistics techniques that compare striations on the barrel of a gun to those on a recovered bullet, CABL is used when no gun is recovered or when bullets are too small or mangled to observe striations. Forensic Analysis: Weighing Bullet Lead Evidence assesses the scientific validity of CABL, finding that the FBI should use a different statistical analysis for the technique and that, given variations in bullet manufacturing processes, expert witnesses should make clear the very limited conclusions that CABL results can support. The report also recommends that the FBI take additional measures to ensure the validity of CABL results, which include improving documentation, publishing details, and improving on training and oversight.
Review of EPA Homeland Security Efforts
Safe Buildings Program Research Implementation Plan
Häftad, Engelska, 2003
637 kr
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The report examines the Environmental Protection Agency's three-year plan for a comprehensive response to a chemical or biological attack on a civilian or public sector facility. The report states that EPA has correctly identified the essential major research areas (detection, containment, decontamination, and disposal) but calls for an initial focus on decontamination and disposal efforts and a longer term research program.
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Existing and Potential Standoff Explosives Detection Techniques examines the scientific techniques currently used as the basis for explosives detection and determines whether other techniques might provide promising research avenues with possible pathways to new detection protocols. This report describe the characteristics of explosives, bombs, and their components that are or might be used to provide a signature for exploitation in detection technology; considers scientific techniques for exploiting these characteristics to detect explosives and explosive devices; discusses the potential for integrating such techniques into detection systems that would have sufficient sensitivity without an unacceptable false-positive rate; and proposes areas for research that might be expected to yield significant advances in practical explosives and bomb detection technology in the near, mid, and long term.
Review of Testing and Evaluation Methodology for Biological Point Detectors
Abbreviated Summary
Häftad, Engelska, 2005
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This report examines the proposed testing methodology and facility that the Department of Defense (DOD) will use to test and evaluate the effectiveness of its detection system against biological warfare agentsa "an issue that impacts battlefield missions as well as homeland security missions. The report assesses a proposal to construct a whole system live agent testing facility at West Center Test Center, Dugway Proving Ground in Utah for testing the Joint Biological Point Detection System (JBPDS). Because of scientific and schedule-related risks, the report recommends an alternate approach that focuses test and evaluation efforts on leveraging existing data, improving simulated biological agents for use in testing, testing in conditions that more closely resemble the actual field conditions where the JBPDS would be deployed, and modeling for predicted performance against actual biological agents. The report concludes that an integrated testing and evaluation plan encompassing all of these factors will be needed.
Water and Sustainable Development
Opportunities for the Chemical Sciences: A Workshop Report to the Chemical Sciences Roundtable
Häftad, Engelska, 2004
568 kr
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Experts in the areas of water science and chemistry from the government, industry, and academic arenas discussed ways to maximize opportunities for these disciplines to work together to develop and apply simple technologies while addressing some of the worlda (TM)s key water and health problems. Since global water challenges cross both scientific disciplines, the chemical sciences have the ability to be a key player in improving the lives of billions of people around the world.
Preparing Chemists and Chemical Engineers for a Globally Oriented Workforce
A Workshop Report to the Chemical Sciences Roundtable
Häftad, Engelska, 2004
491 kr
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Globalizationa "the flow of people, goods, services, capital, and technology across international bordersa "is significantly impacting the chemistry and chemical engineering professions. Chemical companies are seeking new ideas, a trained workforce, and new market opportunities regardless of geographic location. During an October 2003 workshop, leaders in chemistry and chemical engineering from industry, academia, government, and private funding organizations explored the implications of an increasingly global research environment for the chemistry and chemical engineering workforce. The workshop presentations described deficiencies in the current educational system and the need to create and sustain a globally aware workforce in the near future. The goal of the workshop was to inform the Chemical Sciences Roundtable, which provides a science-oriented, apolitical forum for leaders in the chemical sciences to discuss chemically related issues affecting government, industry, and universities.
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Scientists and engineers have long relied on the power of imaging techniques to help see objects invisible to the naked eye, and thus, to advance scientific knowledge. These experts are constantly pushing the limits of technology in pursuit of chemical imaging—the ability to visualize molecular structures and chemical composition in time and space as actual events unfold—from the smallest dimension of a biological system to the widest expanse of a distant galaxy. Chemical imaging has a variety of applications for almost every facet of our daily lives, ranging from medical diagnosis and treatment to the study and design of material properties in new products. In addition to highlighting advances in chemical imaging that could have the greatest impact on critical problems in science and technology, Visualizing Chemistry reviews the current state of chemical imaging technology, identifies promising future developments and their applications, and suggests a research and educational agenda to enable breakthrough improvements.
608 kr
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The sources, distributions, and transformation of organic compounds in the solar system are active study areas as a means to provide information about the evolution of the solar system and the possibilities of life elsewhere in the universe. There are many organic synthesis processes, however, and ambiguity surrounds the relative effectiveness of these processes in explaining the distribution of organic compounds in the solar system. As a consequence, NASA directed the NRC to determine what processes account for the reduced carbon compounds found throughout the solar system and to examine how planetary exploration can advance understanding of this central issue. This report presents a discussion of the chemistry of carbon; an analysis of the formation, modification, and preservation of organic compounds in the solar system; and an assessment of research opportunities and strategies for enhancing our understanding of organic material in the solar system.
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Respirators are used in a variety of workplaces including emergency response, mining operations, construction, manufacturing, and hospitals. In 2001, National Institute of Occupational Safety and Health (NIOSH) and Bureau of Labor Statistics commissioned a nationwide survey of respirator use in the workplace, the results of which were published inA the 2003 report Respirator Usage in Private Sector Firms. The purpose of the survey was to evaluate respirator use and practices, including training practices and the value of respirator manufacturer's instruction, in order to help guide NIOSH respirator certification and research. This National Research Council (NRC) report evaluates the survey in terms of several measuresA such asA the adequacy and appropriateness of the survey instrument, the survey methodology, data analysis, and the conclusions drawn from the data. The NRC report finds that the survey was an important first step in collecting respiratory protection data from a probability sample but that several improvements could be made in survey design and analysis.Based on the review of the survey, the NRC report concludes that data on respirator use would be best provided by employers and employees in the context of the work setting.