Chukwuebuka Egbuna - Böcker

Phytochemicals as Lead Compounds for New Drug Discovery presents complete coverage of the recent advances in the discovery of phytochemicals from medicinal plants as models to the development of new drugs and chemical entities. Functional bioactive compounds of plant origin have been an invaluable source for many human therapeutic drugs and have played a major role in the treatment of diseases around the world. These compounds possess enormous structural and chemical diversity and have led to many important discoveries. This book presents fundament concepts and factors affecting the choice for plant-based products, as well as recent advances in computer-aided drug discovery and FDA drug candidacy acceptance criteria. It also details the various bioactive lead compounds and molecular targets for a range of life-threatening diseases including cancer, diabetes, and neurodegenerative diseases.

Written by a global team of experts, Phytochemicals as Lead Compounds for New Drug Discovery is an ideal resource for drug developers, phytochemists, plant biochemists, food and medicinal chemists, nutritionists and toxicologists, chemical ecologists, taxonomists, analytical chemists, and other researchers in those fields. It will also be very valuable to professors, students, and researchers in this domain.

Presents fundamental concepts and factors affecting choice for plant-based products Details the FDA drug candidacy acceptance criteria, including bottlenecks and way forward Highlights recent advances in computational-based drug discovery Focuses on the discovery of new drugs and potential druggable targets for the treatment of chronic diseases of world importance

Natural Remedies for Pest, Disease and Weed Control presents alternative solutions in the form of eco-friendly, natural remedies. Written by senior researchers and professionals with many years of experience from diverse fields in biopesticides, the book presents scientific information on novel plant families with pesticidal properties and their formulations. It also covers chapters on microbial pest control and control of weeds by allelopathic compounds. This book will be invaluable to plant pathologists, agrochemists, plant biochemists, botanists, environmental chemists and farmers, as well as undergraduate and postgraduate students.

Details microbial biopesticides and other bio-botanical derived pesticides and their formulation Contains case studies for major crops and plants Discuses phytochemicals of plant-derived essential oils

Preparation of Phytopharmaceuticals for the Management of Disorders: The Development of Nutraceuticals and Traditional Medicine presents comprehensive coverage and recent advances surrounding phytopharmaceuticals, nutraceuticals and traditional and alternative systems of medicines. Sections cover the concepts of phytopharmaceuticals, their history, and current highlights in phytomedicine. Also included are classifications of crude drugs, herbal remedies and toxicity, traditional and alternative systems of medicine, nanotechnology applications, and herbal cosmeticology. Final sections cover applications of microbiology and biotechnology in drug discovery.

This book provides key information for everyone interested in drug discovery, including medicinal chemists, nutritionists, biochemists, toxicologists, drug developers and health care professionals. Students, professors and researchers working in the area of pharmaceutical sciences and beyond will also find the book useful.

Includes the history and current highlights in phytomedicine, along with classifications of crude drugs, herbal drug technologies and herbal cosmeticology Provides detailed information on herbal remedies and toxicity, traditional and alternative systems of medicine, and applications of microbiology and biotechnology in drug discovery Discusses the nutritional and health benefits of nutraceuticals and how they help in the management and treatment of metabolic diseases

Phytochemistry, the Military and Health: Phytotoxins and Natural Defenses comes as a response to the gap that there has for so long existed between phytochemistry and survival of both service personnel and civilian communities during and after conflicts. Armed conflicts cause a lot of devastation to communities and should be avoided as much as it can be possible. The devastation is usually evident in service provisions such as Health, Education, Water, and Food among many others. Both service personnel and civilians are affected to various degrees. Facilities usually end up being physically destroyed, with no essential supplies and/or having dysfunctional systems. Going with untreated wounds, communicable and non-communicable diseases for weeks with no medical interventions due to the conflicts, disease burdens heavily weigh down on communities as well as security personnel. To make the situation even more complicated, masses of people are forced to migrate for safety and security reasons, likely going with diseases along wherever they go. In such instances, phytochemicals become handy in providing solutions from first aid, basic analgesia, antimicrobials, and the general improvement of health.

Phytochemicals are known to play a major role in the day to day management of diseases and health. There has been much research into their effectiveness as community medicines and as alternatives to conventional drugs. However, the role that phytochemicals play in the military, counterterrorism, and security has been overlooked. Phytochemistry, the Military and Health: Phytotoxins and Natural Defenses discusses the roles that phytochemicals play as friends and foes in the military, including insights aimed to help develop antidotes against phytochemicals and other chemical agents used maliciously as weapons. Filling a gap between drug discovery, security, and emergency medicine, this book describes which plants can be categorized for protection and controls, which can be helpful in times of conflicts and soon after conflicts, in military operations, and those that can be used as deterrents and as emergency medicines. Carefully designed to show the contribution that phytochemicals play in safety and security, this book is useful for researchers, regulators and anyone interested in plant chemistry.

Covers the contribution that phytochemicals play in safety and security Contains insights that will help in the development of antidotes against phytochemical and other chemical weapons Categorizes plants in terms of their usefulness as well as the potential security risks they possess

Analytical Techniques in Biosciences: From Basics to Applications presents comprehensive and up-to-date information on the various analytical techniques obtainable in bioscience research laboratories across the world. This book contains chapters that discuss the basic bioanalytical protocols and sample preparation guidelines. Commonly encountered analytical techniques, their working principles, and applications were presented. Techniques, considered in this book, include centrifugation techniques, electrophoretic techniques, chromatography, titrimetry, spectrometry, and hyphenated techniques. Subsequent chapters emphasize molecular weight determination and electroanalytical techniques, biosensors, and enzyme assay protocols. Other chapters detail microbial techniques, statistical methods, computational modeling, and immunology and immunochemistry.The book draws from experts from key institutions around the globe, who have simplified the chapters in a way that will be useful to early-stage researchers as well as advanced scientists. It is also carefully structured and integrated sequentially to aid flow, consistency, and continuity. This is a must-have reference for graduate students and researchers in the field of biosciences. Presents basic analytical protocols and sample-preparation guidelines Details the various analytical techniques, including centrifugation, spectrometry, chromatography, and titrimetry Describes advanced techniques such as hyphenated techniques, electroanalytical techniques, and the application of biosensors in biomedical research Presents biostatistical tools and methods and basic computational models in biosciences

Applications of Nanotechnology in Drug Discovery and Delivery, in the Drug Discovery Update series, presents complete coverage of the application of nanotechnology in the discovery of new drugs and efficient target delivery of drugs. The book highlights recent advances of nanotechnology applications in the biomedical sciences, starting with chapters that provide the basics of nanotechnology, nanoparticles and nanocarriers. Part II deals with the application of nanotechnology in drug discovery, with an emphasis on enhanced delivery of pharmaceutical products, with Part III discussing toxicological and safety issues arising from the use of nanomaterials.

This book brings together a global team of experts, making it an essential resource for researchers, drug developers, medicinal chemists, toxicologists and analytical chemists.

Serves as a guide to drug developers working in pharma, biotech and academia, bringing together the latest research on the topic Presents recent information on the use of nanomaterials for the development of drugs using engineered nanocarriers to target specific delivery Features a global team of contributing experts who discuss nanotechnology applications in drug discovery as well as safety issues and challenges

Role of Nutrigenomics in Modern-day Healthcare and Drug Discovery presents novel insights into how these tools can be applied in the study of nutrient-gene interaction for the management of certain disease conditions without using synthetic drugs or other treatments that come with side effects. Divided into three parts, Part I presents chapters that give background information of the subject while laying a framework for other chapters to follow. Part II presents chapters that discuss the role of nutrigenomics in healthcare, while Part III presents chapters that discuss the role of nutrigenomics in modern day drug discovery.

Written by a global team of experts from key institutions around the world, this book is useful for drug developers, medicinal chemists, public health scientists, molecular biologists, biochemists, toxicologists and food scientists.

Provides readers with background information on the role of nutrigenomics in healthcare, with a focus on emerging topics in nutrigenetics and nutrigenomics Presents chapters that discusses the role of nutrigenomics in the modern day drug discovery for the treatment and management of diseases Includes a wide array of definitions, methods, summaries, figures and tables to aid readers with understanding and application

Antidotes to Toxins and Drugs: From Natural Sources to Drug Discovery in Toxicology presents recent advances in the discovery of natural antidotes to toxins, drug intoxications and overdoses in pharmacology, drug discovery and toxicology. The text provides detailed information about toxins and their natural antidotes, along with the identification and screening of antidotes for drug intoxications and overdoses. Written by a global team of experts, it describes the potential uses of natural products in toxicology and their applications in medicine and in the pharmaceutical sciences. This book will be a key resource for drug developers, medicinal chemists and toxicologists, among others.Sections shine a particular focus on mechanisms of action, various principles in pharmacokinetics and pharmacodynamics terms, and possible sources and synthesis techniques for these phytochemicals.Details recent advances in the discovery of natural antidotes from medicinal plants and phytochemicalsIncludes advances in the discovery of antidotes to drug intoxications and overdosesDescribes modern screening assays for toxins and drug intoxicationsFeatures information on recent advances in toxicology

Coronavirus Drug Discovery, Volume 1: SARS-CoV-2 (COVID-19) Prevention, Diagnosis, and Treatment is the first of three volumes presenting comprehensive information on drug discovery against COVID-19. This volume provides background information on the genesis of COVID-19, the epidemiology, transmission, pathogenesis, and mutagenesis. It also presents the various treatment options, drug discovery opportunities and vaccine developmental processes. Written by global team of experts from key institutions across the globe, this book is recommended to all concerned agencies, private research firms, and consortiums working on finding a solution to COVID-19 and its variants. By design, this book will be useful to drug developers, medicinal chemists, pharmacologists, health experts, researchers, students and faculty members in industry and academia.

Presents information on the genesis of COVID-19, global impact and collaborative efforts Details the epidemiology, transmission, pathogenesis, and mutagenesis of SARS-CoV-2 Documents the various treatment options and vaccine development for COVID-19

Phytochemistry, Computational Tools and Databases in Drug Discovery presents the state-of-the-art in computational methods and techniques for drug discovery studies from medicinal plants. Various tools and databases for virtual screening and characterization of plant bioactive compounds and their subsequent predictions on biological targets for the discovery of new drugs against specific diseases are presented, along with computational tools for the prediction of the toxic effects of phytochemicals on living systems. The book also provides in-depth insight on the applications of these computational tools as well as the databases that describe the interactions of phytochemicals with diseases along with predictions for druggable bioactive compounds.

Useful for drug developers, medicinal chemists, toxicologists, phytochemists, plant biochemists and analytical chemists, this book clearly presents the various computational techniques, tools and databases for phytochemical research.

Provides the various databases, methods and procedures for computational drug discovery in plants Includes insights into the predictors for properties of phytochemicals against different diseases Discusses the applications of computational tools and their databases

Computer-Aided Drug Design (CADD): From Ligand-Based Methods to Structure-Based Approaches outlines the basic theoretical principles, methodologies and applications of different fundamental and advanced CADD approaches and techniques. Including information on current protocols as well as recent developments in the computational methods, tools and techniques used for rational drug design, the book explains the fundamental aspects of CADD, combining this with a practical understanding of the various in silico approaches used in modern drug discovery processes to assess the field in a comprehensive and systematic manner.

Providing up-to-date, information and guidance for scientists, researchers, students and teachers, the book helps readers address specific academic and research related problems using illustrative explanations, examples and case studies, which are systematically reviewed.

Highlights in silico approaches to drug design and discovery using computational tools and techniques Details ligand-based and structure-based drug design in a comprehensive and systematic approach Summarizes recent developments in computational drug design strategy as novel approaches of rational drug designing

Coronavirus Drug Discovery, Volume Two: Antiviral Agents from Natural Products and Nanotechnological Applications presents detailed information on drug discovery against COVID-19. Sections in this volume present chapters that focus on the various antiviral agents from natural products that have the propensity to be used as chemical scaffolds for the development of drugs against COVID-19. Also captured are the dietary sources of antioxidant bioactives that may help boost the immune system for the management of COVID-19. Other chapters describe the application of nanotechnology for efficient and effective delivery of drugs against COVID-19.

Written by global team of experts, this book is an excellent resource for drug developers, medicinal chemists, pharmaceutical companies in R&D and research institutes in both academia and industry.

Presents the various antiviral bioactive compounds from natural products Discusses the roles of antioxidant in the prevention and management of COVID-19 Details the application of nanotechnology for efficient and effective drug delivery

Coronavirus Drug Discovery, Volume Three: Druggable Targets and In Silico Update presents comprehensive information on drug discovery against COVID-19. Chapters in Part One of this volume describe the various druggable targets and associated signaling pathways for effective targeting of SARS-CoV-2. In Part Two, chapters discuss the various computational approaches and in silico studies against SARS-CoV-2. Written by global team of experts, this book is an excellent resource that will be extremely useful to drug developers, medicinal chemists, pharmaceutical companies in R&D, research institutes in both academia and industry, and the National Library of Medicines and Health.

In addition, agencies such as the National Institutes of Health, Centers for Disease Control and Prevention, World Health Organization, European Medicines Agency, the US Food and Drug Administration, and all others involved in drug discovery against COVID-19 will find this book useful.

Discusses the pathogenic mechanisms of SARS-CoV-2 and druggable targets Reviews the various signaling pathways associated with SAR-CoV-2 as possible druggable targets Presents computational approaches and in silico studies against SARS-CoV-2

Biochemical and Molecular Pharmacology in Drug Discovery comprises fundamental biochemical and molecular aspects of drug discovery and basic understanding of modern drug discovery approaches, along with certain key topics related to molecular pharmacology of drugs and therapeutics. The book explains the phenomena of drug-target interactions, considering different biochemical systems and cellular strategies. With the advent of technologies, current advances, and research trends move toward molecular and/or target-based drug design and discovery. Through this book, readers will gain skills and knowledge with a thorough understanding of the subject of biochemical and molecular pharmacology in a comprehensive and systematic manner.Molecular pharmacology has gained significant momentum among researchers, scientists, and academicians because of its increasing interest in drug discovery research across the globe. Molecular pharmacology involves a fundamental understanding of drug actions at the molecular level with the help of several tools and techniques of biochemical and molecular biology.

Highlights the fundamentals of biochemical and molecular aspects, with reference to drug discovery researchDepicts modern drug discovery approaches such as reverse pharmacology, drug repositioning, and CADD in the context of current research updatesSummarizes recent developments in the molecular pharmacology of novel drugs/ therapeutic molecules

Drug Discovery and One Health Approach in Combating Infectious Diseases: A Multi-sectoral Approach to address Infections explores the intersection of drug discovery and the One Health Approach, along with the effectiveness of interdisciplinary approaches to combating infectious diseases. The book covers both holistic and innovative drug discovery methodologies and technologies such as natural compounds, harnessing genomics, proteomics, and nanotechnology. Additionally, the book reviews zoonotic diseases, vaccine development, ethical considerations, and regulatory pathways. Practice case studies demonstrate successful One Health and interdisciplinary initiatives to combating infectious disease.This catalogue of knowledge provides a toolbox of innovative and interdisciplinary solutions of complex issues in drug discovery and infectious disease. It will be a valuable resource to professionals and researchers working in the fields of biomedical sciences, pharmaceutical sciences, infectious disease research, and public health, as well as those engaged in drug discovery, development, and the management of infectious diseases.Presents practical case studies on successful One Health initiativesProvides the fundamentals of drug discovery and the One Health approach through an interdisciplinary lensExplains innovative technologies and emerging trends in infectious disease management and drug discovery

Molecular and Cellular Biology Approaches and Applications in Modern Drug Discovery is an essential guide that bridges the latest advances in molecular and cellular biology to revolutionize drug discovery. The book explores a wide range of tools and techniques, and their application to drug discovery, including genetic engineering, gene therapy, regenerative medicine, developmental biology, molecular diagnostics, biomarkers, RNA therapeutics, molecular immunology, and vaccine development. It also considers multi-omics approaches, biophysical methods, epigenetics and epigenomics, biomedical engineering, nanotechnology, artificial intelligence, bioinformatics, structural and computational approaches, and more. This comprehensive volume covers critical domains such as transcriptomics, proteomics, genomics, genetics, and cell signalling pathways, providing an in-depth understanding of their pivotal roles in drug development. It is an invaluable reference for researchers and advanced students working in these areas across molecular biology, biochemistry, pharmacology, biotechnology and related fields.Examines the latest trends shaping the future of drug discovery, including proteomics, transcriptomics, nanotechnology, and AI-driven innovations to revolutionize therapeutic developmentDelves into the transformative realms of genetic engineering, stem cell biology, vaccine development, regenerative medicine, and biomedical engineering, paving the way for future innovationsDelivers practical guidance to address the complexities and hurdles faced in modern drug developmentIntegrates a diverse range of disciplines to provide a holistic approach to drug discovery

Oxylipins are an important class of signaling molecules in plants, which play an important role in plant defence and innate immunity. Oxylipins have critical roles in plant growth and plant responses to physical damage caused by herbivores, insects, and pathogenic microbes. Over the last decade, our understanding of oxylipin production, metabolism, and function, particularly jasmonates, has advanced considerably. Jasmonates have provided further mechanistic insights into enzyme function and signalling cascades. Other oxylipins, such as hydroxy fatty acids, have recently been shown to exhibit individual signaling features and crosstalk with other phytohormones.There is scant literature on plant oxylipins and their relevance to our understanding and therefore, understanding oxylipin production, metabolism, and function is pivotal. As a result, researchers, students, professors, and other book readers will have a thorough understanding of plant oxylipin biosynthesis, structure, and function, assisting in the improvement of plant science.Plant oxylipins: metabolism, physiological roles, and profiling techniques address the mechanism, metabolism, and roles of oxylipins in plant resistance to various biotic and abiotic stimuli in detail. This book covers fundamental ideas in oxylipin production, metabolism, structural biochemistry, and signaling pathways. It also discusses cutting-edge methodologies for oxylipin metabolic profiling, with an emphasis on computing applications. This book is an excellent resource for plant scientists, plant biochemists, biotechnologists, botanists, phytochemists, toxicologists, chemical ecologists, taxonomists, and other scholars in those subjects. The book is written by a global team of professionals. Features Presents concrete and extensive information about a basic and applied aspect of plant oxylipins as well as expanded coverage of signaling mechanisms. Highlights the fundamental concepts of the biosynthesis, metabolism, structural biochemistry, and signaling pathway of oxylipins. Details the state-of-the-art methods and techniques in metabolic profiling of oxylipins in plants. Presents insights on computational applications in the evaluation and study of oxylipins in plants.

NEGLECTED TROPICAL DISEASES AND PHYTOCHEMICALS IN DRUG DISCOVERY Explore novel drug discovery updates from medicinal plants to help fight the devastating effects of neglected tropical diseases Neglected Tropical Diseases and Phytochemicals in Drug Discovery delivers a comprehensive exploration of the drug discovery process as it pertains to neglected tropical diseases. The book covers recent advancements in drug discovery, as well as druggable targets and new challenges facing the industry. It offers readers expansive discussions of specific diseases, including protozoan, helminth, bacterial, viral, fungal, and ectoparasitic infections. This book provides readers with insightful perspectives from leading industry voices on fifty years of trends and progress in the search for new, safe, and affordable therapeutic drugs in the fight against neglected tropical diseases. It includes information beneficial to researchers in a variety of fields of biology, chemistry, medicine, and pharmaceuticals. The distinguished authors cover topics including the effects of phytochemicals on the causative agent of leprosy and the potential applicability of phytochemicals in the management of Dengue fever. Readers will also enjoy the inclusion of: Thorough introductions to neglected tropical diseases, phytochemicals, protein targets, and mechanisms in drug discovery, as well as the epidemiology of neglected tropical diseasesAn exploration of novel bioactive lead compounds for drug discovery against neglected tropical diseases, leishmaniasis, lymphatic filariasis, trypanosomiasis, and schistosomiasisDiscussions of protozoan infections, including herbal, nutritional, and traditional remedies for giardiasis and the anti-leishmanial potentials of phytochemicalsExaminations of helminth infections, including the prospects of phytochemicals in the treatment of helminthiasisPerfect for medicinal chemists, drug developers, and research and development scientists, Neglected Tropical Diseases and Phytochemicals in Drug Discovery will also earn a place in the libraries of toxicologists and researchers in biology, chemistry, medicinal chemistry, ethnobotany, and bioinformatics seeking a one-stop resource for drug discovery for neglected tropical diseases.

Focusing on phytochemicals and their potential for drug discovery, this book offers a comprehensive resource on poisonous plants and their applications in chemistry and in pharmacology. Provides a comprehensive resource on phytotoxins, covering historical perspectives, modern applications, and their potential in drug discoveryCovers the mechanisms, benefits, risks and management protocols of phytotoxins in a scientific laboratory and the usefulness in drug discoveryPresents chapters in a carefully designed, clear order, making it an ideal resource for the academic researcher or the industry professional at any stage in their career

PHYTOCHEMICAL DRUG DISCOVERY FOR CENTRAL NERVOUS SYSTEM DISORDERS Understand herbal and plant-based treatments for chronic disorders with this groundbreaking work Due in part to the aging of the global population, disorders of the central nervous system have become an increasingly grave public health concern in recent years. Demand for pharmaceutical treatments has been correspondingly high, but there are many barriers to the successful development of effective synthetic drugs. Phytomedicines, or plant-based and herbal medicines, have proven to be an effective alternative, boasting lower toxicity and cost and higher efficacy, and one that demands greater research and broader-based practitioner knowledge. Phytochemical Drug Discovery for Central Nervous System Disorders meets this demand with a timely, clearly-structured guide. It thorough coverage presents a wide range of phytochemicals with potential as candidates for drug discovery, describing their sources, properties, and therapeutic efficacy. The result is a vital contribution to the ongoing fight against central nervous system (CNS) disorders. Phytochemical Drug Discovery for Central Nervous System Disorders readers will also find: Detailed treatment of CNS-active plant products, neuroprotective chemicals, plant-based nutraceutical products, and moreUp-to-date information on FDA-approved drugs and existing plant-based products used to treat CNS disordersAn authorial team featuring experts from across the globePhytochemical Drug Discovery for Central Nervous System Disorders is essential for drug discovery scientists, drug developers, medicinal chemists, biochemists, and any researchers and professionals in the health care or pharmaceutical industries.

This book details recent advances in the applications of nanobiofertilizers as a substitute for synthetic fertilizers in boosting food production. With the steady rise of the world’s population, there is a need to increase the production of safe and nutritious food. The constant loss of arable land, as a result of various anthropogenic activities from human action, has become a threat to global biodiversity and ecosystems. Additionally, the issue of climate change has imposed many obstacles to increasing agricultural productivity, especially from biotic and abiotic stressors and temperature-limited environments, such as in high altitudes or seasonally hot regions. Because of these factors, there is a need to adopt sustainable and modern technologies that can boost and improve the rate of food production. One of the cheapest means of enhancing sustainable food production is to explore natural and unlimited beneficial microorganisms, particularly those that can increase the level of soil fertility, improve crop production and health, improve tolerance to stress, support nutrient uptake and availability, and boost natural biodiversity. The synergetic effect of nanotechnology and beneficial microorganisms for the effective bio-fabrication of nanobiofertilizers, is a sustainable solution for producing pesticide-free food. This book provides a deep insight into microbial diversity, recent techniques used for the isolation, screening, and characterization of beneficial microorganisms with eco-friendly attributes, used for bioengineering of nanobiofertilizers, as well as the application of proteomics, metabolomics, genomics, and bioinformatics. The book also covers commercialization, patents, and the business and socio-economic aspects of nanobiofertilizers, as well as the role of policymakers, stakeholders, and government agencies in the translation of nanobioferilizer research into policy. Audience The book is a useful resource for a diverse audience, including industrialists, food industry professionals, agriculturists, agricultural microbiologists, plant pathologists, botanists, microbiologists, biotechnologists, nanotechnologists, microbial biotechnologists, farmers, policymakers, and extension workers.

This unique, important, and timely book provides detailed information about the application of nanochitosan to increase agricultural productivity to enhance food security and nutrition. Readers will find in Nanochitosan Applications for Enhanced Crop Production and Food Security detailed state-of-the-art information including: The modes of action through which nanochitosan perform numerous biological activities;State-of-the-art information and recent advancements in the application of nanochitosan, including targeted delivery, genetic manipulation, antimicrobial uses, curing infections in plants, controlled delivery of biologically active constituents, applications in the evaluation of carbon dioxide concentrations and humidity in controlled greenhouse environments, and their use as pressure sensors in agrichemical spraying equipment;Information on applying nanochitosan as a biofertilizer and bioinsecticide when applied on seeds and for foliar spraying of agricultural crops, soil amendment, and protection against pathogens and pests;The application of nanochitosan in the manufacturing of nanosensors in precision farming in the determination of crop growth, condition of soils, penetration of agrochemicals, diseases, and the level of environmental pollution to ensure a high level of safety for plant and soil health.Audience Researchers, scientists, and graduate students in agriculture, crop science, agricultural biotechnology, and agricultural engineering applications of nanochitosan, as well as policymakers, entrepreneurs, and investors in agriculture and food security.

The book is essential for those seeking to understand innovative and sustainable solutions to global food insecurity and health challenges, as it offers invaluable insights into the transformative potential of mushroom biotechnology and its applications. The intervention of microbial biotechnology in various sectors has displayed remarkable growth linked to sustainable innovations and biotechnological utilization of beneficial microorganisms, such as mushrooms, for the benefit of humanity. Recent advancements in mushroom biotechnology will prove successful due to mushrooms’ nature as natural problem solvers, including their ability to enhance nutritional values obtained from agricultural crops, sustained health benefits derived from pharmacologically active substances used to manage human diseases, and improve crop production.This book will serve as one of the first volumes addressing the usefulness of mushroom biotechnology, giving detailed state-of-the-art information on recent advancements and how the industry could maximize profits. The volume will also assist the pharmaceutical and medical sectors by examining the discovery of novel pharmacological and bioactive compounds that could replace the various adverse effects when using synthetic drugs. It presents a simple, adaptable, reproducible methodology that will help researchers and scientists adopt these methodologies for similar projects.Readers will find that the book: Presents recent advances in the application of mushroom biotechnology in various sectors (food, agriculture, and health) for sustainable innovations for optimum benefit of mankind;Details applications of mushrooms for sustainable agriculture through their plant growth-promoting attributes and management of pests and diseases in plants and soils;Discusses the discovery of novel pharmacological substances from mushrooms for applications in the biomedical sector.AudienceThe book is valuable reference work for scientists and researchers working in the fields of pharmaceutical sciences, agricultural microbiology, plant pathology, botany, agriculture, microbiology, biotechnology, nanotechnology, environmental microbiology, and microbial biotechnology.

This first book in this three-volume set provides comprehensive coverage of a wide range of topics in phytochemistry. With chapters from professional specialists from key institutions around the world, the volume starts with an introduction to phytochemistry and details the fundamentals. Part II discusses the state-of-the-art modern methods and techniques in phytochemical research, while Part III provides an informative overview of computational phytochemistry and its applications. Part IV presents novel research findings in the discovery of drugs that will be effective in the treatment of diseases. The chapters are drawn carefully and integrated sequentially to aid flow, consistency, and continuity.

As volume 2 of this three-volume set on phytochemistry, this book features chapters that comprehensively review a selection of important recent advances in ethnopharmacology and alternative and complementary medicines. It also presents many informative chapters on the medicinal potential of phytochemicals in the treatment and management of various diseases, such as cancer, diabetes, diabetic nephropathy, autoimmune diseases, neurological disorders, male infertility, and more.

This volume presents chapters that discuss secondary metabolites of marine origin, the industrial applications of phytochemicals, and recent advances in phytochemical research. It considers production of secondary metabolites and accumulations through in vitro cultures and also reviews the effects of natural products as biopesticides and as eco-friendly corrosion inhibitors. In addition, the volume discusses the effects of the environment on the distribution of phytochemicals and the roles of phytochelatins and heavy metal tolerance in plants.

Key features include: Details the role of plants for the treatment and management of cancer and diabetes Discusses the role of phytocompounds as ligands for cancer and diabetic targets Reviews plants and the potential of phytochemicals as antidiabetic and anticancer drugs Explores the green biosynthesis of nanoparticles and their treatment efficiency

This first book in this three-volume set provides comprehensive coverage of a wide range of topics in phytochemistry. With chapters from professional specialists from key institutions around the world, the volume starts with an introduction to phytochemistry and details the fundamentals. Part II discusses the state-of-the-art modern methods and techniques in phytochemical research, while Part III provides an informative overview of computational phytochemistry and its applications. Part IV presents novel research findings in the discovery of drugs that will be effective in the treatment of diseases. The chapters are drawn carefully and integrated sequentially to aid flow, consistency, and continuity.

As volume 2 of this three-volume set on phytochemistry, this book features chapters that comprehensively review a selection of important recent advances in ethnopharmacology and alternative and complementary medicines. It also presents many informative chapters on the medicinal potential of phytochemicals in the treatment and management of various diseases, such as cancer, diabetes, diabetic nephropathy, autoimmune diseases, neurological disorders, male infertility, and more.