Gang Liu - Böcker

Medicinal Chemistry and Drug Development describes the key events and roles of medicinal chemistry in the discovery and development of lead compounds into drugs, including target identification, which is accomplished by using 30 case studies. This book outlines all the stages of drug development, including the discovery of active compounds, research on the pharmacologicalproperties of molecules, and confirmation of drug targets. The role of the case studies is to show the common factors in the successful development of drugs, thereby showing medicinal chemists how best to explore the scientific pathways when developing new drugs. This makes the book especially relevant for senior university students majoring in pharmaceutical sciences as well as graduate students and researchers.Provides unique information on different drug development case studiesIntegrates pharmaceutical knowledge-mainly medicinal chemistry-with new drug development thinkingDescribes using case studies, the impact of key events in drug development and on drug efficacy

This book offers a comprehensive overview of the epidemiology, etiology, and pathophysiology of chronic obstructive pulmonary disease (COPD). It addresses the limitations of existing drug delivery methods and explores advanced delivery systems to overcome these challenges, providing an exhaustive account of their intricate mechanisms. The introductory chapters elucidate pathways responsible for COPD progression, followed by a detailed analysis of established biomarkers and potential targets in contemporary COPD therapy. Subsequent chapters provide insights into ongoing treatment modalities, their efficacy, drawbacks, and prospective solutions to counter the setbacks of COPD therapy. The subsequent section covers state-of-the-art drug delivery technologies and novel drug formulations designed to enhance drug deposition and absorption in COPD lungs. It further explores a methodical yet coordinated explanation of targeted personalized therapies and emerging approaches, including nanoparticles, polymeric carriers, and vesicular delivery systems. Toward the end, the book discusses ongoing and completed clinical trials encompassing the management of COPD through advanced drug delivery approaches. It serves as a valuable resource for professionals, scientists, academicians, and clinicians specializing in respiratory health.Provides an in-depth understanding of the epidemiology, etiology, and pathophysiology of Chronic Obstructive Pulmonary Disease (COPD)Delve into pathways responsible for COPD progression, conducting a detailed analysis of established biomarkers and potential targets in contemporary COPD therapyOffer insights into ongoing treatment modalities, evaluating their efficacy, drawbacks, and proposing prospective solutions to counter the setbacks of COPD therapySystematically organizes information on state-of-the-art drug delivery technologies and novel formulations designed to enhance drug deposition and absorption in COPD lungsPresents a methodical explanation of targeted personalized therapies and emerging approaches, including nanoparticles, polymeric carriers, and vesicular delivery systems

This book looks at Generative Artificial Intelligence (GAI) and Knowledge Management Systems (KMS). It explains the design considerations to implement Generative AI in practice.The book looks at the evolving digital environment and discusses how organizations may effectively manage knowledge through emerging technologies. Chapters cover theory, design and implementation, and case studies from industry players. These case studies will focus on organization implementation experiences to draw out applicable frameworks, principles and best practices. This provides readers with essential insights into future technology development trends.Providing a methodological approach to designing and deploying GAI-based KMS in business, this book will appeal to academic researchers, industrial practitioners, students, and anyone interested in GAI-based KMS.

This book presents a comprehensive range of topics in deep learning for polymer discovery, from fundamental concepts to advanced methodologies. The authors begin with essential knowledge on polymer data representations and neural network architectures, then progress to deep learning frameworks for property prediction and inverse polymer design.

This book systematically discusses the basic concepts, theories, research and latest trends in image fusion. Further, it introduces readers to a new category: edge-preserving-based image fusion, and provides an overview of image fusion based on machine learning and deep learning.

This book systematically discusses the basic concepts, theories, research and latest trends in image fusion. Further, it introduces readers to a new category: edge-preserving-based image fusion, and provides an overview of image fusion based on machine learning and deep learning.

This book presents the progress, changes, and evolvement for apple mechanical harvest during the past decades, which include, but not limited to, bulky harvest method, harvest platform, apple infield sorting, and harvest robotics.

This book presents the progress, changes, and evolvement for apple mechanical harvest during the past decades, which include, but not limited to, bulky harvest method, harvest platform, apple infield sorting, and harvest robotics.

With the recently well developed areas of Internet of Thing, consumer wearable gadgets and artificial intelligence, flexible and stretchable electronic devices have spurred great amount of interest from both the global scientific and industrial communities. As an emerging technology, flexible and stretchable electronics requires the scale-span fabrication of devices involving nano-features, microstructures and macroscopic large area manufacturing. The key factor behind covers the organic, inorganic and nano materials that exhibit completely different mechanical and electrical properties, as well as the accurate interfacial control between these components. Based on the fusion of chemistry, physics, biology, materials science and information technology, this review volume will try to offer a timely and comprehensive overview on the flexible and stretchable electronic materials and devices. The book will cover the working principle, materials selection, device fabrication and applications of electronic components of transistors, solar cells, memories, sensors, supercapacitors, circuits and etc.