Michael Chappell – författare

This introduction to medical imaging introduces all of the major medical imaging techniques in wide use in both medical practice and medical research, including Computed Tomography, Ultrasound, Positron Emission Tomography, Single Photon Emission Tomography and Magnetic Resonance Imaging. Principles of Medical Imaging for Engineers introduces fundamental concepts related to why we image and what we are seeking to achieve to get good images, such as the meaning of ‘contrast’ in the context of medical imaging. This introductory text separates the principles by which ‘signals’ are generated and the subsequent ‘reconstruction’ processes, to help illustrate that these are separate concepts and also highlight areas in which apparently different medical imaging methods share common theoretical principles. Exercises are provided in every chapter, so the student reader can test their knowledge and check against worked solutions and examples.

The text considers firstly the underlying physical principles by which information about tissues within the body can be extracted in the form of signals, considering the major principles used: transmission, reflection, emission and resonance. Then, it goes on to explain how these signals can be converted into images, i.e., full 3D volumes, where appropriate showing how common methods of ‘reconstruction’ are shared by some imaging methods despite relying on different physics to generate the ‘signals’. Finally, it examines how medical imaging can be used to generate more than just pictures, but genuine quantitative measurements, and increasingly measurements of physiological processes, at every point within the 3D volume by methods such as the use of tracers and advanced dynamic acquisitions.

 Principles of Medical Imaging for Engineers will be of use to engineering and physical science students and graduate students with an interest in biomedical engineering, and to their lecturers.

This book provides an introduction to qualitative and quantitative aspects of human physiology. It examines biological and physiological processes and phenomena, including a selection of mathematical models, showing how physiological problems can be mathematically formulated and studied. It also illustrates how a wide range of engineering and physics topics, such as electronics, fluid dynamics, solid mechanics and control theory can be used to describe and understand physiological processes and systems. Throughout the text, there are introductions to measuring and quantifying physiological processes using both signaling and imaging technologies. This new edition includes updated material on pathophysiology, metabolism and the TCA cycle, as well as more advanced worked examples.

This book introduces both qualitative and quantitative aspects of human physiology through language and concepts familiar to engineers and other physical scientists. It looks at biological and physiological processes and phenomena, including a selection of mathematical models, showing how physiological problems can be mathematically formulated and studied. It also illustrates how a wide range of engineering and physics topics, including electronics, fluid dynamics, solid mechanics and control theory can be used to describe and understand physiological processes and systems. Throughout the text there are introductions to measuring and quantifying physiological processes using both signal and imaging technologies.  Physiology for Engineers describes the basic structure and models of cellular systems, the structure and function of the cardiovascular system, the electrical and mechanical activity of the heart and provides an overview of the structure and function of the respiratory and nervous systems. It also includes an introduction to the basic concepts and applications of reaction kinetics, compartmental modelling and its application to pharmacokinetics and tracer kinetics.  The book is of interest to final year biomedical engineering undergraduates and graduate students alike, as well as to practising engineers new to the fields of bioengineering or medical physics. This new edition is fully revised and updated with two completely rewritten chapters on compartmental modelling, demonstrated in application to pharmacokinetics, and multi-scale modelling demonstrated by how to go from “from cells to tissue” in describing physiological systems. The book contains interleaved exercises to make the book even more useful for instructors and students for a one-semester course. 

This textbook is a concise introduction to medical imaging aimed at physical scientists and engineers, including budding biomedical engineers and biophysicists. The book introduces fundamental concepts related to how we "see" inside the body using medical imaging technology and what is needed to obtain useful images.

The text first considers the underlying physical principles by which information about tissues within the body can be extracted in the form of signals, examining the major principles used: transmission, reflection, emission, and resonance. It then explains how these signals can be converted into images, i.e., full 3D volumes, demonstrating how common methods of "reconstruction" are shared by some imaging techniques, despite relying on different physics to generate the "signals." Finally, it explores how medical imaging can be used to generate more than just pictures, but genuine quantitative measurements, and increasingly, measurements of physiological processes at every point within the 3D volume using methods such as tracers and advanced dynamic acquisitions.

Now in its second, fully updated and expanded edition, the textbook contains new sections on image analysis concepts, covers a wide range of techniques used to enhance and interpret medical imaging, and includes concise introductions to optimization and machine learning in their application to medical imaging . The second edition also includes expanded discussions on quantitative, functional, physiological, and metabolic imaging.

''Principles of Medical Imaging for Engineers’ second edition will be invaluable to students and graduate students in engineering and physical sciences with an interest in biomedical engineering, as well as to their professors.