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This reference book provides a comprehensive overview of models and therapeutic approaches against neurodegenerative diseases, including Parkinson’s disease, Alzheimer’s disease, Huntington’s disease, and amyotrophic lateral sclerosis. It explores models based on the chemical, induced, cellular, genetic, transgenic, and 3D organoid approaches in neurodegenerative diseases. The book also reviews advantages and limitations of these models in designing the treatment strategies. Additionally, the book covers the emerging field of bioinformatics and its application in modeling various neurodegenerative diseases. Towards the end, the book highlights the role of holistic management, precision medicine, OMICS, and gene therapy against neurodegenerative disorders. It examines the implications and significance of stem cells therapy in translational models of neurodegenerative diseases. This book is an invaluable resource for researchers, neuroscientists, and neurosurgeons for getting in-depth information on the neurodegenerative models and therapeutic approaches.
Key Features:
Provides a comprehensive overview of neurodegenerative diseases and their models Examines the limitations associated with modeling neurodegenerative diseases Presents novel treatment strategies for Alzheimer''s disease using cellular models Reviews importance of 3D organoid models for therapeutic approaches in Parkinson''s disease Covers modeling techniques in understanding prion diseases Explores the role of genetic models in understanding Huntington''s disease936 kr
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This reference book provides a comprehensive overview of models and therapeutic approaches against neurodegenerative diseases, including Parkinson’s disease, Alzheimer’s disease, Huntington’s disease, and amyotrophic lateral sclerosis. It explores models based on the chemical, induced, cellular, genetic, transgenic, and 3D organoid approaches in neurodegenerative diseases. The book also reviews advantages and limitations of these models in designing the treatment strategies. Additionally, the book covers the emerging field of bioinformatics and its application in modeling various neurodegenerative diseases. Towards the end, the book highlights the role of holistic management, precision medicine, OMICS, and gene therapy against neurodegenerative disorders. It examines the implications and significance of stem cells therapy in translational models of neurodegenerative diseases. This book is an invaluable resource for researchers, neuroscientists, and neurosurgeons for getting in-depth information on the neurodegenerative models and therapeutic approaches.
Key Features:
Provides a comprehensive overview of neurodegenerative diseases and their models Examines the limitations associated with modeling neurodegenerative diseases Presents novel treatment strategies for Alzheimer''s disease using cellular models Reviews importance of 3D organoid models for therapeutic approaches in Parkinson''s disease Covers modeling techniques in understanding prion diseases Explores the role of genetic models in understanding Huntington''s disease936 kr
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This book explores the pivotal role of synaptic plasticity in the pathogenesis, progression, and potential treatment of neurodegenerative disorders. The initial chapter provides an in-depth understanding of the complexity and impact of neurodegenerative conditions. It discusses the association of mitochondrial dysfunction, epigenetic influences, and neuroinflammation with synaptic plasticity in neurodegenerative diseases. The following chapters review the dynamic changes that occur at the cellular and synaptic levels in Parkinson''s disease, Alzheimer''s disease, and Huntington''s disease, paving the way for innovative therapeutic strategies. Furthermore, the book presents various computational tools and methodologies essential for enhancing our understanding of synaptic plasticity. It examines the transformative role of artificial intelligence tools in addressing synaptic impairment across various neurodegenerative diseases.
Discusses the role of synaptic plasticity in neurodegenerative diseases, shedding light on how dynamic changes occur at the cellular and synaptic levels Explores the transformative role of artificial intelligence tools in addressing synaptic impairment across various neurodegenerative diseases Provides a comprehensive overview of neurodegenerative disorders, including pathogenesis, etiology, and treatment strategies Presents tools and techniques used to simulate the complex system biology of synaptic plasticity Examines the role of computational neuroscience in understanding and potentially treating conditions such as multiple sclerosis and amyotrophic lateral sclerosisToward the end, the book explores the role of synaptic impairment and computational neuroscience in understanding and potentially treating conditions such as multiple sclerosis and amyotrophic lateral sclerosis. With its multifaceted approach, this book serves as a useful resource for researchers, clinicians, and students in the fields of neuroscience, computational biology, and neurology.
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This book explores the pivotal role of synaptic plasticity in the pathogenesis, progression, and potential treatment of neurodegenerative disorders. The initial chapter provides an in-depth understanding of the complexity and impact of neurodegenerative conditions. It discusses the association of mitochondrial dysfunction, epigenetic influences, and neuroinflammation with synaptic plasticity in neurodegenerative diseases. The following chapters review the dynamic changes that occur at the cellular and synaptic levels in Parkinson''s disease, Alzheimer''s disease, and Huntington''s disease, paving the way for innovative therapeutic strategies. Furthermore, the book presents various computational tools and methodologies essential for enhancing our understanding of synaptic plasticity. It examines the transformative role of artificial intelligence tools in addressing synaptic impairment across various neurodegenerative diseases.
Discusses the role of synaptic plasticity in neurodegenerative diseases, shedding light on how dynamic changes occur at the cellular and synaptic levels Explores the transformative role of artificial intelligence tools in addressing synaptic impairment across various neurodegenerative diseases Provides a comprehensive overview of neurodegenerative disorders, including pathogenesis, etiology, and treatment strategies Presents tools and techniques used to simulate the complex system biology of synaptic plasticity Examines the role of computational neuroscience in understanding and potentially treating conditions such as multiple sclerosis and amyotrophic lateral sclerosisToward the end, the book explores the role of synaptic impairment and computational neuroscience in understanding and potentially treating conditions such as multiple sclerosis and amyotrophic lateral sclerosis. With its multifaceted approach, this book serves as a useful resource for researchers, clinicians, and students in the fields of neuroscience, computational biology, and neurology.
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This reference book explores the multifaceted problem of heavy metal contamination in the environment. Through its in-depth analysis, the book provides a thorough overview of the sources and pathways of heavy metals, their persistence in ecosystems, and the resulting health impacts on individuals and ecosystems. The chapters explore the diverse sources of contamination, including industrial activities, mining, agriculture, and urbanization, while examining the types of heavy metals found in the environment and their toxicological properties. The book further reviews the profound health effects associated with heavy metal exposure, such as neurological disorders, developmental abnormalities, carcinogenicity, and organ damage. Furthermore, the book provides insights into risk assessment methodologies, regulatory frameworks, and guidelines aimed at controlling and minimizing heavy metal exposure. It highlights the challenges and gaps in current regulations, identifies potential areas for improvement, and presents analytical techniques for heavy metal analysis and removal. This book is an important source for researchers and professionals working in the fields of environmental science, toxicology, and public health.
917 kr
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This reference book explores the multifaceted problem of heavy metal contamination in the environment. Through its in-depth analysis, the book provides a thorough overview of the sources and pathways of heavy metals, their persistence in ecosystems, and the resulting health impacts on individuals and ecosystems. The chapters explore the diverse sources of contamination, including industrial activities, mining, agriculture, and urbanization, while examining the types of heavy metals found in the environment and their toxicological properties. The book further reviews the profound health effects associated with heavy metal exposure, such as neurological disorders, developmental abnormalities, carcinogenicity, and organ damage. Furthermore, the book provides insights into risk assessment methodologies, regulatory frameworks, and guidelines aimed at controlling and minimizing heavy metal exposure. It highlights the challenges and gaps in current regulations, identifies potential areas for improvement, and presents analytical techniques for heavy metal analysis and removal. This book is an important source for researchers and professionals working in the fields of environmental science, toxicology, and public health.
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