Sarah H. Beachy – författare
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27 produkter
Applying Systems Thinking to Regenerative Medicine
Proceedings of a Workshop
Av Forum on Regenerative Medicine, Board on Health Sciences Policy m. fl.
E-bok, 2021
589 kr
Lägg i varukorg
Regenerative medicine products, which are intended to repair or replace damaged cells or tissues in the body, include a range of therapeutic approaches such as cell- and gene-based therapies, engineered tissues, and non-biologic constructs. The current approach to characterizing the quality of a …
Integrating Large-Scale Genomic Information into Clinical Practice
Workshop Summary
Av Roundtable on Translating Genomic-Based Research for Health, Board on Health Sciences Policy m. fl.
E-bok, 2012
535 kr
Lägg i varukorg
The initial sequencing of the human genome, carried out by an international group of experts, took 13 years and $2.7 billion to complete. In the decade since that achievement, sequencing technology has evolved at such a rapid pace that today a consumer can have his or her entire genome sequenced by …
Improving the Efficiency and Effectiveness of Genomic Science Translation
Workshop Summary
Av Institute of Medicine, Board on Health Sciences Policy m. fl.
Häftad, 2014
389 kr
Lägg i varukorg
The process for translating basic science discoveries into clinical applications has historically involved a linear and lengthy progression from initial discovery to preclinical testing, regulatory evaluation and approval, and, finally, use in clinical practice. The low rate of translation from …
Improving the Efficiency and Effectiveness of Genomic Science Translation
Workshop Summary
Av Roundtable on Translating Genomic-Based Research for Health, Board on Health Sciences Policy m. fl.
E-bok, 2014
535 kr
Lägg i varukorg
The process for translating basic science discoveries into clinical applications has historically involved a linear and lengthy progression from initial discovery to preclinical testing, regulatory evaluation and approval, and, finally, use in clinical practice. The low rate of translation from …
Refining Processes for the Co-Development of Genome-Based Therapeutics and Companion Diagnostic Tests
Workshop Summary
Av Institute of Medicine, Board on Health Sciences Policy m. fl.
Häftad, 2014
347 kr
Lägg i varukorg
Many drug developers have examined new strategies for creating efficiencies in their development processes, including the adoption of genomics-based approaches. Genomic data can identify new drug targets for both common and rare diseases, can predict which patients are likely to respond to a …
Refining Processes for the Co-Development of Genome-Based Therapeutics and Companion Diagnostic Tests
Workshop Summary
Av Roundtable on Translating Genomic-Based Research for Health, Board on Health Sciences Policy m. fl.
E-bok, 2014
489 kr
Lägg i varukorg
Many drug developers have examined new strategies for creating efficiencies in their development processes, including the adoption of genomics-based approaches. Genomic data can identify new drug targets for both common and rare diseases, can predict which patients are likely to respond to a …
Conflict of Interest and Medical Innovation
Ensuring Integrity While Facilitating Innovation in Medical Research: Workshop Summary
Av Institute of Medicine, Board on Health Sciences Policy m. fl.
Häftad, 2014
416 kr
Lägg i varukorg
Scientific advances such as the sequencing of the human genome have created great promise for improving human health by providing a greater understanding of disease biology and enabling the development of new drugs, diagnostics, and preventive services. However, the translation of research advances …
Conflict of Interest and Medical Innovation
Ensuring Integrity While Facilitating Innovation in Medical Research: Workshop Summary
Av Roundtable on Translating Genomic-Based Research for Health, Board on Health Sciences Policy m. fl.
E-bok, 2014
571 kr
Lägg i varukorg
Scientific advances such as the sequencing of the human genome have created great promise for improving human health by providing a greater understanding of disease biology and enabling the development of new drugs, diagnostics, and preventive services. However, the translation of research advances …
Drug Repurposing and Repositioning
Workshop Summary
Av Roundtable on Translating Genomic-Based Research for Health, Board on Health Sciences Policy m. fl.
E-bok, 2014
553 kr
Lägg i varukorg
Drug development can be time-consuming and expensive. Recent estimates suggest that, on average, it takes 10 years and at least $1 billion to bring a drug to market. Given the time and expense of developing drugs de novo, pharmaceutical companies have become increasingly interested in finding new …
Stem Cell Therapies
Opportunities for Ensuring the Quality and Safety of Clinical Offerings: Summary of a Joint Workshop by the Institute of Medicine, the National Academy of Sciences, and the International Society for Stem Cell Research
Av Board on Health Sciences Policy, Institute of Medicine m. fl.
E-bok, 2014
554 kr
Lägg i varukorg
Stem cells offer tremendous promise for advancing health and medicine. Whether being used to replace damaged cells and organs or else by supporting the body''s intrinsic repair mechanisms, stem cells hold the potential to treat such debilitating conditions as Parkinson''s disease, diabetes, and …
Assessing Genomic Sequencing Information for Health Care Decision Making
Workshop Summary
Av Roundtable on Translating Genomic-Based Research for Health, Board on Health Sciences Policy m. fl.
E-bok, 2014
642 kr
Lägg i varukorg
Rapid advances in technology have lowered the cost of sequencing an individual''s genome from the several billion dollars that it cost a decade ago to just a few thousand dollars today and have correspondingly greatly expanded the use of genomic information in medicine. Because of the lack of …
Improving Genetics Education in Graduate and Continuing Health Professional Education
Workshop Summary
Av Roundtable on Translating Genomic-Based Research for Health, Board on Health Sciences Policy m. fl.
E-bok, 2015
607 kr
Lägg i varukorg
Many health care providers do not have either the knowledge or the tools they need in order to apply genetic information in their day-to-day practices. This lack of support is contributing to a substantial delay in the translation of genetic research findings, when appropriate, into improvement in …
Genomics-Enabled Learning Health Care Systems
Gathering and Using Genomic Information to Improve Patient Care and Research: Workshop Summary
Av Roundtable on Translating Genomic-Based Research for Health, Board on Health Sciences Policy m. fl.
E-bok, 2015
553 kr
Lägg i varukorg
The inclusion of genomic data in a knowledge-generating health care system infrastructure is one promising way to harness the full potential of that information to provide better patient care. In such a system, clinical practice and research influence each other with the goal of improving the …
Applying an Implementation Science Approach to Genomic Medicine
Workshop Summary
Av Roundtable on Translating Genomic-Based Research for Health, Board on Health Sciences Policy m. fl.
E-bok, 2016
607 kr
Lägg i varukorg
Although it is becoming increasingly more common for clinicians to use genomic data in their practices for disease prevention, diagnosis, and treatment, the process of integrating genomic data into the practice of medicine has been a slow and challenging one. Some of the major barriers impeding the …
Deriving Drug Discovery Value from Large-Scale Genetic Bioresources
Proceedings of a Workshop
Av Roundtable on Genomics and Precision Health, and Translation Forum on Drug Discovery, Development m. fl.
E-bok, 2016
646 kr
Lägg i varukorg
The process of discovering and developing a new drug or therapy is extremely costly and time consuming, and recently, it has been estimated that the creation of a new medicine costs on average more than $2 billion and takes 10 years to reach patients. The challenges associated with bringing new …
Exploring the State of the Science in the Field of Regenerative Medicine
Challenges of and Opportunities for Cellular Therapies: Proceedings of a Workshop
Av Forum on Regenerative Medicine, Board on Health Sciences Policy m. fl.
E-bok, 2017
660 kr
Lägg i varukorg
Regenerative medicine holds the potential to create living, functional cells and tissues that can be used to repair or replace those that have suffered potentially irreparable damage due to disease, age, traumatic injury, or genetic and congenital defects. The field of regenerative medicine is …
Enabling Precision Medicine
The Role of Genetics in Clinical Drug Development: Proceedings of a Workshop
Av and Translation Forum on Drug Discovery, Development, Roundtable on Genomics and Precision Health m. fl.
E-bok, 2017
855 kr
Lägg i varukorg
Those involved in the drug development process face challenges of efficiency and overall sustainability due in part to high research costs, lengthy development timelines, and late-stage drug failures. Novel clinical trial designs that enroll participants based on their genetics represent a …
Navigating the Manufacturing Process and Ensuring the Quality of Regenerative Medicine Therapies
Proceedings of a Workshop
Av Forum on Regenerative Medicine, Board on Health Sciences Policy m. fl.
E-bok, 2017
874 kr
Lägg i varukorg
On June 26, 2017, the Forum on Regenerative Medicine hosted a public workshop in Washington, DC, titled Navigating the Manufacturing Process and Ensuring the Quality of Regenerative Medicine Therapies in order to examine and discuss the challenges, opportunities, and best practices associated with …
Understanding Disparities in Access to Genomic Medicine
Proceedings of a Workshop
Av Roundtable on Genomics and Precision Health, Board on Health Sciences Policy m. fl.
E-bok, 2018
874 kr
Lägg i varukorg
Genomic medicine is defined as the routine use of genomic information about an individual as part of his or her clinical care as well as the health outcomes and policy implications of that clinical use. It is one approach that has the potential to improve the quality of health care by allowing …
Exploring Novel Clinical Trial Designs for Gene-Based Therapies
Proceedings of a Workshop
Av Forum on Regenerative Medicine, Board on Health Sciences Policy m. fl.
E-bok, 2020
731 kr
Lägg i varukorg
Recognizing the potential design complexities and ethical issues associated with clinical trials for gene therapies, the Forum on Regenerative Medicine of the National Academies of Sciences, Engineering, and Medicine held a 1-day workshop in Washington, DC, on November 13, 2019. Speakers at the …
Exploring the Current Landscape of Consumer Genomics
Proceedings of a Workshop
Av Roundtable on Genomics and Precision Health, Board on Health Sciences Policy m. fl.
E-bok, 2020
820 kr
Lägg i varukorg
Consumer genomics, encompassing both direct-to-consumer applications (i.e., genetic testing that is accessed by a consumer directly from a commercial company apart from a health care provider) and consumer-driven genetic testing (i.e., genetic testing ordered by a health care provider in response …
Examination of Emerging Bioethical Issues in Biomedical Research
Proceedings of a Workshop
Av Board on Health Sciences Policy, Health and Medicine Division m. fl.
E-bok, 2020
874 kr
Lägg i varukorg
On February 26, 2020, the Board on Health Sciences Policy of the National Academies of Sciences, Engineering, and Medicine hosted a 1-day public workshop in Washington, DC, to examine current and emerging bioethical issues that might arise in the context of biomedical research and to consider …
Examining the State of the Science of Mammalian Embryo Model Systems
Proceedings of a Workshop
Av Board on Health Sciences Policy, Health and Medicine Division m. fl.
E-bok, 2020
855 kr
Lägg i varukorg
Because of the recent advances in embryo modeling techniques, and at the request of the Office of Science Policy in the Office of the Director at the National Institutes of Health, the National Academies of Sciences, Engineering, hosted a 1-day public workshop that would explore the state of the …
Role of Digital Health Technologies in Drug Development
Proceedings of a Workshop
Av and Translation Forum on Drug Discovery, Development, Roundtable on Genomics and Precision Health m. fl.
E-bok, 2020
952 kr
Lägg i varukorg
On March 24, 2020, a 1-day public workshop titled The Role of Digital Health Technologies in Drug Development was convened by the National Academies of Sciences, Engineering, and Medicine. This workshop builds on prior efforts to explore how virtual clinical trials facilitated by digital health …
Understanding the Role of the Immune System in Improving Tissue Regeneration
Proceedings of a Workshop
Av Forum on Regenerative Medicine, Board on Health Sciences Policy m. fl.
E-bok, 2022
589 kr
Lägg i varukorg
The Forum on Regenerative Medicine of the National Academies of Sciences, Engineering, and Medicine convened a two-day virtual public workshop to address knowledge gaps in the understanding of promising approaches to manipulate the immune system and/or the regenerative medicine product to improve …
Rethinking Race and Ethnicity in Biomedical Research
Av and Medicine National Academies of Sciences, Engineering, Health and Medicine Division m. fl.
Häftad, 2025
347 kr
Lägg i varukorg
In 2023, the National Academies convened an expert committee to assess the current use of racial and ethnic categories in biomedical research, review existing guidance for researchers, and provide new guidance for future use. The resulting 2025 report, Rethinking Race and Ethnicity in Biomedical …
Rethinking Race and Ethnicity in Biomedical Research
Av Committee on the Use of Race and Ethnicity in Biomedical Research, Board on Health Sciences Policy m. fl.
E-bok, 2025
517 kr
Lägg i varukorg
In 2023, the National Academies convened an expert committee to assess the current use of racial and ethnic categories in biomedical research, review existing guidance for researchers, and provide new guidance for future use. The resulting 2024 report, Rethinking Race and Ethnicity in Biomedical …
