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      Radiotheranostics Two Volume Set

      AvCari Borrás,Michael G. Stabin

      Taylor & Francis Ltd

      2025

      Del i serien Series in Medical Physics and Biomedical Engineering

      6 863 kr

      Beställningsvara. Skickas inom 10-15 vardagar. Fri frakt över 249 kr.

      Beskrivning

      The first volume addresses the Physics. Chemistry, Biology and Clinical Applications of Radiotheranostics.This book covers scientific, clinical, and educational aspects of radiotheranostics in cancer control. Setting the framework, the first volume defines radiotheranostics and describes the history of radionuclide therapy and theranostics, and the biology of cancer. It examines the clinical applications of unconjugated radionuclides, such as ¹³¹I and ²²³Ra, and of radionuclide-conjugated cancer-specific vectors: peptides, small molecules, antibodies, and nanoparticles; introduces clinical trials and drug development; and reviews epidemiological studies and the adverse effects of radionuclide therapy – both radiation injuries and chemical toxicity. It presents the chemistry and physics of radionuclide production, discusses radioactivity measurements and traceability, and addresses important instrumentation aspects: calibration, quantitative imaging, and quality control. Volume I concludes with guidance on the education, training, and competence of a radiotheranostic multidisciplinary team and summarizes the principal physics characteristics of theranostics today – including many to be expanded in the second volume – while offering a glimpse into tomorrow. This volume provides the foundations for the more advanced second volume, which explores dosimetric and radiation safety, aiming to empower medical physicists and demonstrate to the cancer community how to improve cancer control and yield increased patient survival times.It will be a valuable reference for medical and health physicists with basic knowledge of nuclear medicine.The second volume covers Radiation Chemistry, Radiation biology, Dosimetry, Safety, Economics and Artificial Intelligence aspects of Radiotheranostics.The book expands upon the radiotheranostic topics in cancer care covered in Volume I, which includes cancer biology, clinical applications, radionuclide production, source calibration, imaging instrumentation, and staff education, training, and competencies. Building on these foundational elements, Volume II offers in-depth coverage of radiopharmaceutical preparation and radiolabeling strategies. It presents new insights into radiation biology, including studies on human and animal radiation embryology. The dosimetry section addresses alpha-, beta-, and Auger-emitting radionuclides and explores the therapeutic potential of positrons. It emphasizes biokinetic modeling, standardized and image-based dosimetry procedures, and the quantification of uncertainties in dose calculations. Essential safety topics are also thoroughly examined, including radiation shielding, facility design, the management of deceased radiotheranostic patients, and current regulatory requirements. The volume concludes with forward-looking chapters on the economics of theranostics and the transformative role of artificial intelligence in enhancing precision medicine. The chapters are designed to equip medical physicists with the tools necessary to accurately estimate and document individual patient dosimetry and demonstrate the clinical value of dose calculations in improving cancer outcomes and survival rates. The book is intended for academic and practicing clinical medical and health physicists with a basic knowledge of nuclear medicine. Although not structured as a textbook, medical physicists in nuclear medicine physics training will also find the book helpful.Key Features:Provides a comprehensive introduction to the topic, presenting readers with thorough treatment in a cohesive two-volume book.Presents a rigorous approach while remaining accessible to students and trainees in the field.Contains consistent and extensive references to allow readers to delve deeper into the subject.

      Produktinformation

      • Märke:Taylor & Francis Ltd
      • Utgivningsdatum:2025-11-25
      • Höjd:178 x 254 x undefined mm
      • Vikt:1 050 g
      • Språk:Engelska
      • Serie:Series in Medical Physics and Biomedical Engineering
      • Antal sidor:480
      • Förlag:Taylor & Francis Ltd
      • EAN:9781041143086

      Utforska kategorier

      • Onkologi inom Medicin
      • Medicinsk bildbehandling inom Medicin
      • Förlossningsvård inom Medicin

      Mer om författaren

      Cari (Caridad) Borrás is a certified medical physicist in Washington, DC, USA, where she works as an international consultant and has an adjunct faculty position at the George Washington University School of Medicine and Health Sciences. She obtained a Doctor of Science (Physics) degree from the University of Barcelona, Spain, having done a thesis research project on the dosimetry and embryological effects of Astatine- 211 at Thomas Jefferson University in Philadelphia, PA, USA, as a Fulbright scholar. The American Board of Radiology certified her in Radiological Physics and the American Board of Medical Physics in Medical Health Physics. She has worked as a radiological physicist in Barcelona, Spain; Philadelphia, PA; San Francisco, CA; Recife, Brazil; and Washington, DC, where for 15 years she was responsible for the Radiological Health Program of the Pan American / World Health Organization. She has lectured in more than 300 seminars/courses/congresses, many organized by her; authored/contributed around 100 articles and six book chapters; and edited/coedited three books. She is a Fellow of ACR, AAPM, IOMP, HPS, and IUPESM, and has received awards/recognitions from SEFM, AAPM, ALFIM, IOMP, IUPESM, ACCE, ACR, and ABR.Michael G. Stabin is a Certified Health Physicist, President of the Radiation Dose Assessment Resource, Inc., living in Kennewick, WA, USA, where he worked for NV5 – Technical Engineering & Consulting Solutions and Hanford Mission Integration Solutions. He was an Associate Professor in the Radiology and Radiological Sciences Department at Vanderbilt University, in Nashville, TN, and a Scientist at the Radiation Internal Dose Information Center of Oak Ridge Institute for Science and Education. He received a Ph.D. in Nuclear Engineering (Health Physics emphasis) from the University of Tennessee, is a member of the HPS and the SNMMI, and is also a Fulbright scholar. He has over 225 publications in the open literature, most on internal dosimetry for nuclear medicine applications, including complete textbooks on health physics and internal dose assessment.

      Innehållsförteckning

      • Volume OneList of Common AcronymsPart 1 – IntroductionChapter 1 What is radiotheranostics?Chapter 2 History of radionuclide therapy and theranosticsChapter 3 Biological principles behind targeted radionuclide therapy for cancerPart 2 – Clinical Applications of Targeted Radionuclide Therapy in Cancer ControlChapter 4 Unconjugated radionuclidesChapter 5 Radionuclide-conjugated cancer-specific vectors: PeptidesChapter 6 Radionuclide-conjugated cancer-specific vectors: Small Molecules and antibodiesChapter 7 Radionuclide-conjugated cancer-specific vectors: NanoparticlesChapter 8 Introduction to clinical trials and drug development for radionuclide therapiesChapter 9 Epidemiologic Studies of Cancer Risk among Patients Administered RadionuclidesChapter 10 Adverse effects of radionuclide therapyPart 3 – Radiation Chemistry and PhysicsChapter 11 Radionuclide productionChapter 12 Radioactivity measurement and traceabilityChapter 13 Instrumentation, calibration, quantitative imaging, and quality controlPart 4 - The FutureChapter 14 Human resources: Multidisciplinary team education, training, and competenceChapter 15 Theranostics today: Looking backwards to tomorrowVolume TwoList of Common AcronymsPart 1 – IntroductionChapter 1. Radiotheranostics: Challenges TodayPart 2 – Radiochemistry and RadiobiologyChapter 2. Radiopharmaceutical Preparations and Radiolabeling StrategiesChapter 3. New Insights Into the Radiation Biology of RadiotheranosticsChapter 4. Radiation Embryology: Human and Animal StudiesPart 3 – Particle DosimetryChapter 5. Alpha- and Beta-particle Therapy and DosimetryChapter 6. Auger EmittersChapter 7. Positrons: Their Potential Role in Radionuclide TherapyPart 4 – Dosimetry FormalismsChapter 8. Biokinetic Modelling For Radionuclide DosimetryChapter 9. Standardized Tumor and Organ DosimetryChapter 10. Image-based Dosimetry ProceduresChapter 11. Combining External Beam Radiotherapy and Radionuclide TherapyChapter 12. Uncertainties in Dose CalculationsPart 5 – SafetyChapter 13. Design, Shielding, and Operational Radiation Safety Aspects of the Radiotheranostic FacilityChapter 14. Management of Deceased Patients Under Treatment (Radioactive Cadavers)Chapter 15. Radiopharmaceutical Regulatory RequirementsPart 6 – Future Directions and OpportunitiesChapter 16. The Economics of TheranosticsChapter 17. Artificial intelligence in Radiotheranostics
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