Cari (Caridad) Borrás is a certified medical physicist in Washington, DC, USA, where she works as an international consultant and has an adjunct faculty position at the George Washington University School of Medicine and Health Sciences. She obtained a Doctor of Science (Physics) degree from the University of Barcelona, Spain, having done a thesis research project on the dosimetry and embryological effects of Astatine- 211 at Thomas Jefferson University in Philadelphia, PA, USA, as a Fulbright scholar. The American Board of Radiology certified her in Radiological Physics and the American Board of Medical Physics in Medical Health Physics. She has worked as a radiological physicist in Barcelona, Spain; Philadelphia, PA; San Francisco, CA; Recife, Brazil; and Washington, DC, where for 15 years she was responsible for the Radiological Health Program of the Pan American / World Health Organization. She has lectured in more than 300 seminars/courses/congresses, many organized by her; authored/contributed around 100 articles and six book chapters; and edited/coedited three books. She is a Fellow of ACR, AAPM, IOMP, HPS, and IUPESM, and has received awards/recognitions from SEFM, AAPM, ALFIM, IOMP, IUPESM, ACCE, ACR, and ABR.Michael G. Stabin is a Certified Health Physicist, President of the Radiation Dose Assessment Resource, Inc., living in Kennewick, WA, USA, where he worked for NV5 – Technical Engineering & Consulting Solutions and Hanford Mission Integration Solutions. He was an Associate Professor in the Radiology and Radiological Sciences Department at Vanderbilt University, in Nashville, TN, and a Scientist at the Radiation Internal Dose Information Center of Oak Ridge Institute for Science and Education. He received a Ph.D. in Nuclear Engineering (Health Physics emphasis) from the University of Tennessee, is a member of the HPS and the SNMMI, and is also a Fulbright scholar. He has over 225 publications in the open literature, most on internal dosimetry for nuclear medicine applications, including complete textbooks on health physics and internal dose assessment.

• Volume OneList of Common AcronymsPart 1 – IntroductionChapter 1 What is radiotheranostics?Chapter 2 History of radionuclide therapy and theranosticsChapter 3 Biological principles behind targeted radionuclide therapy for cancerPart 2 – Clinical Applications of Targeted Radionuclide Therapy in Cancer ControlChapter 4 Unconjugated radionuclidesChapter 5 Radionuclide-conjugated cancer-specific vectors: PeptidesChapter 6 Radionuclide-conjugated cancer-specific vectors: Small Molecules and antibodiesChapter 7 Radionuclide-conjugated cancer-specific vectors: NanoparticlesChapter 8 Introduction to clinical trials and drug development for radionuclide therapiesChapter 9 Epidemiologic Studies of Cancer Risk among Patients Administered RadionuclidesChapter 10 Adverse effects of radionuclide therapyPart 3 – Radiation Chemistry and PhysicsChapter 11 Radionuclide productionChapter 12 Radioactivity measurement and traceabilityChapter 13 Instrumentation, calibration, quantitative imaging, and quality controlPart 4 - The FutureChapter 14 Human resources: Multidisciplinary team education, training, and competenceChapter 15 Theranostics today: Looking backwards to tomorrowVolume TwoList of Common AcronymsPart 1 – IntroductionChapter 1. Radiotheranostics: Challenges TodayPart 2 – Radiochemistry and RadiobiologyChapter 2. Radiopharmaceutical Preparations and Radiolabeling StrategiesChapter 3. New Insights Into the Radiation Biology of RadiotheranosticsChapter 4. Radiation Embryology: Human and Animal StudiesPart 3 – Particle DosimetryChapter 5. Alpha- and Beta-particle Therapy and DosimetryChapter 6. Auger EmittersChapter 7. Positrons: Their Potential Role in Radionuclide TherapyPart 4 – Dosimetry FormalismsChapter 8. Biokinetic Modelling For Radionuclide DosimetryChapter 9. Standardized Tumor and Organ DosimetryChapter 10. Image-based Dosimetry ProceduresChapter 11. Combining External Beam Radiotherapy and Radionuclide TherapyChapter 12. Uncertainties in Dose CalculationsPart 5 – SafetyChapter 13. Design, Shielding, and Operational Radiation Safety Aspects of the Radiotheranostic FacilityChapter 14. Management of Deceased Patients Under Treatment (Radioactive Cadavers)Chapter 15. Radiopharmaceutical Regulatory RequirementsPart 6 – Future Directions and OpportunitiesChapter 16. The Economics of TheranosticsChapter 17. Artificial intelligence in Radiotheranostics

Cari (Caridad) Borrás is a certified medical physicist in Washington, DC, USA, where she works as an international consultant and has an adjunct faculty position at the George Washington University School of Medicine and Health Sciences. She obtained a Doctor of Science (Physics) degree from the University of Barcelona, Spain, having done a thesis research project on the dosimetry and embryological effects of Astatine- 211 at Thomas Jefferson University in Philadelphia, PA, USA, as a Fulbright scholar. The American Board of Radiology certified her in Radiological Physics and the American Board of Medical Physics in Medical Health Physics. She has worked as a radiological physicist in Barcelona, Spain; Philadelphia, PA; San Francisco, CA; Recife, Brazil; and Washington, DC, where for 15 years she was responsible for the Radiological Health Program of the Pan American / World Health Organization. She has lectured in more than 300 seminars/courses/congresses, many organized by her; authored/contributed around 100 articles and six book chapters; and edited/coedited three books. She is a Fellow of ACR, AAPM, IOMP, HPS, and IUPESM, and has received awards/recognitions from SEFM, AAPM, ALFIM, IOMP, IUPESM, ACCE, ACR, and ABR.Michael G. Stabin is a Certified Health Physicist, President of the Radiation Dose Assessment Resource, Inc., living in Kennewick, WA, USA, where he worked for NV5 – Technical Engineering & Consulting Solutions and Hanford Mission Integration Solutions. He was an Associate Professor in the Radiology and Radiological Sciences Department at Vanderbilt University, in Nashville, TN, and a Scientist at the Radiation Internal Dose Information Center of Oak Ridge Institute for Science and Education. He received a Ph.D. in Nuclear Engineering (Health Physics emphasis) from the University of Tennessee, is a member of the HPS and the SNMMI, and is also a Fulbright scholar. He has over 225 publications in the open literature, most on internal dosimetry for nuclear medicine applications, including complete textbooks on health physics and internal dose assessment.

• Volume OneList of Common AcronymsPart 1 – IntroductionChapter 1 What is radiotheranostics?Chapter 2 History of radionuclide therapy and theranosticsChapter 3 Biological principles behind targeted radionuclide therapy for cancerPart 2 – Clinical Applications of Targeted Radionuclide Therapy in Cancer ControlChapter 4 Unconjugated radionuclidesChapter 5 Radionuclide-conjugated cancer-specific vectors: PeptidesChapter 6 Radionuclide-conjugated cancer-specific vectors: Small Molecules and antibodiesChapter 7 Radionuclide-conjugated cancer-specific vectors: NanoparticlesChapter 8 Introduction to clinical trials and drug development for radionuclide therapiesChapter 9 Epidemiologic Studies of Cancer Risk among Patients Administered RadionuclidesChapter 10 Adverse effects of radionuclide therapyPart 3 – Radiation Chemistry and PhysicsChapter 11 Radionuclide productionChapter 12 Radioactivity measurement and traceabilityChapter 13 Instrumentation, calibration, quantitative imaging, and quality controlPart 4 - The FutureChapter 14 Human resources: Multidisciplinary team education, training, and competenceChapter 15 Theranostics today: Looking backwards to tomorrowVolume TwoList of Common AcronymsPart 1 – IntroductionChapter 1. Radiotheranostics: Challenges TodayPart 2 – Radiochemistry and RadiobiologyChapter 2. Radiopharmaceutical Preparations and Radiolabeling StrategiesChapter 3. New Insights Into the Radiation Biology of RadiotheranosticsChapter 4. Radiation Embryology: Human and Animal StudiesPart 3 – Particle DosimetryChapter 5. Alpha- and Beta-particle Therapy and DosimetryChapter 6. Auger EmittersChapter 7. Positrons: Their Potential Role in Radionuclide TherapyPart 4 – Dosimetry FormalismsChapter 8. Biokinetic Modelling For Radionuclide DosimetryChapter 9. Standardized Tumor and Organ DosimetryChapter 10. Image-based Dosimetry ProceduresChapter 11. Combining External Beam Radiotherapy and Radionuclide TherapyChapter 12. Uncertainties in Dose CalculationsPart 5 – SafetyChapter 13. Design, Shielding, and Operational Radiation Safety Aspects of the Radiotheranostic FacilityChapter 14. Management of Deceased Patients Under Treatment (Radioactive Cadavers)Chapter 15. Radiopharmaceutical Regulatory RequirementsPart 6 – Future Directions and OpportunitiesChapter 16. The Economics of TheranosticsChapter 17. Artificial intelligence in Radiotheranostics

Cari (Caridad) Borrás is a certified medical physicist in Washington, DC, USA, where she works as an international consultant and has an adjunct faculty position at the George Washington University School of Medicine and Health Sciences. She obtained a Doctor of Science (Physics) degree from the University of Barcelona, Spain, having done a thesis research project on the dosimetry and embryological effects of Astatine- 211 at Thomas Jefferson University in Philadelphia, PA, USA, as a Fulbright scholar. The American Board of Radiology certified her in Radiological Physics and the American Board of Medical Physics in Medical Health Physics. She has worked as a radiological physicist in Barcelona, Spain; Philadelphia, PA; San Francisco, CA; Recife, Brazil; and Washington, DC, where for 15 years she was responsible for the Radiological Health Program of the Pan American / World Health Organization. She has lectured in more than 300 seminars/courses/congresses, many organized by her; authored/contributed around 100 articles and six book chapters; and edited/coedited three books. She is a Fellow of ACR, AAPM, IOMP, HPS, and IUPESM, and has received awards/recognitions from SEFM, AAPM, ALFIM, IOMP, IUPESM, ACCE, ACR, and ABR.Michael G. Stabin is a Certified Health Physicist, President of the Radiation Dose Assessment Resource, Inc., living in Kennewick, WA, USA, where he worked for NV5 – Technical Engineering & Consulting Solutions and Hanford Mission Integration Solutions. He was an Associate Professor in the Radiology and Radiological Sciences Department at Vanderbilt University, in Nashville, TN, and a Scientist at the Radiation Internal Dose Information Center of Oak Ridge Institute for Science and Education. He received a Ph.D. in Nuclear Engineering (Health Physics emphasis) from the University of Tennessee, is a member of the HPS and the SNMMI, and is also a Fulbright scholar. He has over 225 publications in the open literature, most on internal dosimetry for nuclear medicine applications, including complete textbooks on health physics and internal dose assessment.

• Volume OneList of Common AcronymsPart 1 – IntroductionChapter 1 What is radiotheranostics?Chapter 2 History of radionuclide therapy and theranosticsChapter 3 Biological principles behind targeted radionuclide therapy for cancerPart 2 – Clinical Applications of Targeted Radionuclide Therapy in Cancer ControlChapter 4 Unconjugated radionuclidesChapter 5 Radionuclide-conjugated cancer-specific vectors: PeptidesChapter 6 Radionuclide-conjugated cancer-specific vectors: Small Molecules and antibodiesChapter 7 Radionuclide-conjugated cancer-specific vectors: NanoparticlesChapter 8 Introduction to clinical trials and drug development for radionuclide therapiesChapter 9 Epidemiologic Studies of Cancer Risk among Patients Administered RadionuclidesChapter 10 Adverse effects of radionuclide therapyPart 3 – Radiation Chemistry and PhysicsChapter 11 Radionuclide productionChapter 12 Radioactivity measurement and traceabilityChapter 13 Instrumentation, calibration, quantitative imaging, and quality controlPart 4 - The FutureChapter 14 Human resources: Multidisciplinary team education, training, and competenceChapter 15 Theranostics today: Looking backwards to tomorrowVolume TwoList of Common AcronymsPart 1 – IntroductionChapter 1. Radiotheranostics: Challenges TodayPart 2 – Radiochemistry and RadiobiologyChapter 2. Radiopharmaceutical Preparations and Radiolabeling StrategiesChapter 3. New Insights Into the Radiation Biology of RadiotheranosticsChapter 4. Radiation Embryology: Human and Animal StudiesPart 3 – Particle DosimetryChapter 5. Alpha- and Beta-particle Therapy and DosimetryChapter 6. Auger EmittersChapter 7. Positrons: Their Potential Role in Radionuclide TherapyPart 4 – Dosimetry FormalismsChapter 8. Biokinetic Modelling For Radionuclide DosimetryChapter 9. Standardized Tumor and Organ DosimetryChapter 10. Image-based Dosimetry ProceduresChapter 11. Combining External Beam Radiotherapy and Radionuclide TherapyChapter 12. Uncertainties in Dose CalculationsPart 5 – SafetyChapter 13. Design, Shielding, and Operational Radiation Safety Aspects of the Radiotheranostic FacilityChapter 14. Management of Deceased Patients Under Treatment (Radioactive Cadavers)Chapter 15. Radiopharmaceutical Regulatory RequirementsPart 6 – Future Directions and OpportunitiesChapter 16. The Economics of TheranosticsChapter 17. Artificial intelligence in Radiotheranostics