AAPS Advances in the Pharmaceutical Sciences Series – serie
Visar alla böcker i serien AAPS Advances in the Pharmaceutical Sciences Series. Handla med fri frakt och snabb leverans.
101 produkter
Clinical Trial Simulations
Applications and Trends
Av Holly H. C. Kimko, Carl C. Peck
Inbunden, 2010
2815 kr
Lägg i varukorg
This edition includes both updates and new uses and issues concerning CTS, along with case studies of how clinical trial simulations are being applied in various therapeutic and application areas. Importantly, the book expands on the utility of CTS for informing decisions during drug development …
Drug Product Development for the Back of the Eye
Av Uday B. Kompella, Henry F. Edelhauser
Inbunden, 2011
2253 kr
Lägg i varukorg
This comprehensive volume discusses approaches for a systematic selection of delivery systems for various classes of therapeutic agents including small molecule, protein, and nucleic acid drugs. Specific topics covered in this book include:Solution, suspension, gel, nanoparticle, microparticle, and …
Formulating Poorly Water Soluble Drugs
Av Robert O. Williams III, Alan B. Watts m. fl.
Inbunden, 2011
2188 kr
Lägg i varukorg
This volume is intended to provide the reader with a breadth of understanding regarding the many challenges faced with the formulation of poorly water-soluble drugs as well as in-depth knowledge in the critical areas of development with these compounds. Further, this book is designed to provide …
Clinical Trial Simulations
Applications and Trends
Av Holly H. C. Kimko, Carl C. Peck
Häftad, 2013
2316 kr
Lägg i varukorg
This edition includes both updates and new uses and issues concerning CTS, along with case studies of how clinical trial simulations are being applied in various therapeutic and application areas. Importantly, the book expands on the utility of CTS for informing decisions during drug development …
Drug Product Development for the Back of the Eye
Av Uday B. Kompella, Henry F. Edelhauser
Häftad, 2013
2253 kr
Lägg i varukorg
This comprehensive volume discusses approaches for a systematic selection of delivery systems for various classes of therapeutic agents including small molecule, protein, and nucleic acid drugs. Specific topics covered in this book include:Solution, suspension, gel, nanoparticle, microparticle, and …
Microdialysis in Drug Development
Inbunden, 2012
1692 kr
Lägg i varukorg
A vast number of diagnostic and therapeutic decisions are based on measuring blood concentrations of molecules, yet most biochemical and pharmacological events actually take place in the tissues. Microdialysis is a key semi-invasive sampling technique to measure in vivo drug penetration to the …
Global Approach in Safety Testing
ICH Guidelines Explained
Av Jan Willem van der Laan, Joseph J DeGeorge
Inbunden, 2013
1692 kr
Lägg i varukorg
This volume will consider one of ICH’s major categories, Safety i.e. topics relating to in vitro and in vivo pre-clinical studies (Carcinogenicity Testing, Genotoxicity Testing, etc.). Since the start of the ICH process, many guidelines have been written, but even after ICH6 no explanations have …
Sterile Product Development
Formulation, Process, Quality and Regulatory Considerations
Av Parag Kolhe, Mrinal Shah m. fl.
Inbunden, 2013
3707 kr
Lägg i varukorg
This comprehensive book encompasses various facets of sterile product development. Key concepts relevant to the successful development of sterile products are illustrated through case studies and are covered under three sections in this book:• Formulation approaches that discuss a variety of dosage …
Transporters in Drug Development
Discovery, Optimization, Clinical Study and Regulation
Av Yuichi Sugiyama, Bente Steffansen
Inbunden, 2013
1692 kr
Lägg i varukorg
Transporters in Drug Development examines how membrane transporters can be dealt with in academic–industrial drug discovery and pharmaceutical development as well as from a regulatory perspective. The book describes methods and examples of in vitro characterization of single transporters in the …
Pharmaco-Imaging in Drug and Biologics Development
Fundamentals and Applications
Av Brian R. Moyer, Narayan P.S. Cheruvu m. fl.
Inbunden, 2013
1917 kr
Lägg i varukorg
The volume aim to be a comprehensive overview of the drug and biologic development process that is often called “the valley of death” (pre-IND through approval) where high costs of studies and high rates of product failure are part of the drug development landscape. Imaging tools can serve in this …
Melt Extrusion
Materials, Technology and Drug Product Design
Av Michael A. Repka, Nigel Langley m. fl.
Inbunden, 2013
1692 kr
Lägg i varukorg
This volume provides readers with the basic principles and fundamentals of extrusion technology and a detailed description of the practical applications of a variety of extrusion processes, including various pharma grade extruders. In addition, the downstream production of films, pellets and …
Formulating Poorly Water Soluble Drugs
Av Robert O. Williams III, Alan B. Watts m. fl.
Häftad, 2014
2253 kr
Lägg i varukorg
This volume is intended to provide the reader with a breadth of understanding regarding the many challenges faced with the formulation of poorly water-soluble drugs as well as in-depth knowledge in the critical areas of development with these compounds. Further, this book is designed to provide …
Global Approach in Safety Testing
ICH Guidelines Explained
Av Jan Willem van der Laan, Joseph J DeGeorge
Häftad, 2015
1692 kr
Lägg i varukorg
This volume will consider one of ICH’s major categories, Safety i.e. topics relating to in vitro and in vivo pre-clinical studies (Carcinogenicity Testing, Genotoxicity Testing, etc.). Since the start of the ICH process, many guidelines have been written, but even after ICH6 no explanations have …
Microdialysis in Drug Development
Häftad, 2014
1243 kr
Lägg i varukorg
A vast number of diagnostic and therapeutic decisions are based on measuring blood concentrations of molecules, yet most biochemical and pharmacological events actually take place in the tissues. Microdialysis is a key semi-invasive sampling technique to measure in vivo drug penetration to the …
FDA Bioequivalence Standards
Inbunden, 2014
2515 kr
Lägg i varukorg
This comprehensive reference provides an in-depth discussion on state-of-the-art regulatory science in bioequivalence. In sixteen chapters, the volume explores a broad range of topics pertaining to bioequivalence, including its origin and principles, statistical considerations, food effect studies, …
Applied Pharmacometrics
Av Stephan Schmidt, Hartmut Derendorf
Inbunden, 2014
3061 kr
Lägg i varukorg
This comprehensive volume provides an update on the current state of pharmacometrics in drug development. It consists of nineteen chapters all written by leading scientists from the pharmaceutical industry, regulatory agencies and academia. After an introduction of the basic pharmacokinetic and …
Discovering and Developing Molecules with Optimal Drug-Like Properties
Av Allen C Templeton, Stephen R. Byrn m. fl.
Inbunden, 2014
2188 kr
Lägg i varukorg
This authoritative volume provides a contemporary view on the latest research in molecules with optimal drug-like properties. It is a valuable source to access current best practices as well as new research techniques and strategies. Written by leading scientists in their fields, the text consists …
Hydrophilic Matrix Tablets for Oral Controlled Release
Av Peter Timmins, Samuel R. Pygall m. fl.
Inbunden, 2014
1643 kr
Lägg i varukorg
This detailed volume addresses key issues and subtle nuances involved in developing hydrophilic matrix tablets as an approach to oral controlled release. It brings together information from more than five decades of research and development on hydrophilic matrix tablets and provides perspective on …
Quality by Design for Biopharmaceutical Drug Product Development
Av Feroz Jameel, Susan Hershenson m. fl.
Inbunden, 2015
2590 kr
Lägg i varukorg
This volume explores the application of Quality by Design (QbD) to biopharmaceutical drug product development. Twenty-eight comprehensive chapters cover dosage forms, liquid and lyophilized drug products. The introductory chapters of this book define key elements of QbD and examine how these …
Biobetters
Protein Engineering to Approach the Curative
Av Amy Rosenberg, Barthélemy Demeule
Inbunden, 2015
1692 kr
Lägg i varukorg
“Biobetters: Protein Engineering to Approach the Curative” discusses the optimization of protein therapeutic products for treatment of human diseases. It is based on the fact that though numerous important therapeutic protein products have been developed for life threatening and chronic diseases …
Applied Pharmacometrics
Av Stephan Schmidt, Hartmut Derendorf
Häftad, 2016
3152 kr
Lägg i varukorg
This comprehensive volume provides an update on the current state of pharmacometrics in drug development. It consists of nineteen chapters all written by leading scientists from the pharmaceutical industry, regulatory agencies and academia. After an introduction of the basic pharmacokinetic and …
Hydrophilic Matrix Tablets for Oral Controlled Release
Av Peter Timmins, Samuel R. Pygall m. fl.
Häftad, 2016
1692 kr
Lägg i varukorg
This detailed volume addresses key issues and subtle nuances involved in developing hydrophilic matrix tablets as an approach to oral controlled release. It brings together information from more than five decades of research and development on hydrophilic matrix tablets and provides perspective on …
Discovering and Developing Molecules with Optimal Drug-Like Properties
Av Allen C Templeton, Stephen R. Byrn m. fl.
Häftad, 2016
2253 kr
Lägg i varukorg
This authoritative volume provides a contemporary view on the latest research in molecules with optimal drug-like properties. It is a valuable source to access current best practices as well as new research techniques and strategies. Written by leading scientists in their fields, the text consists …
Biobetters
Protein Engineering to Approach the Curative
Av Amy Rosenberg, Barthélemy Demeule
Häftad, 2016
1692 kr
Lägg i varukorg
“Biobetters: Protein Engineering to Approach the Curative” discusses the optimization of protein therapeutic products for treatment of human diseases. It is based on the fact that though numerous important therapeutic protein products have been developed for life threatening and chronic diseases …
Quality by Design for Biopharmaceutical Drug Product Development
Av Feroz Jameel, Susan Hershenson m. fl.
Häftad, 2016
2590 kr
Lägg i varukorg
This volume explores the application of Quality by Design (QbD) to biopharmaceutical drug product development. Twenty-eight comprehensive chapters cover dosage forms, liquid and lyophilized drug products. The introductory chapters of this book define key elements of QbD and examine how these …
Pharmaco-Imaging in Drug and Biologics Development
Fundamentals and Applications
Av Brian R. Moyer, Narayan P.S. Cheruvu m. fl.
Häftad, 2016
1687 kr
Lägg i varukorg
The volume aim to be a comprehensive overview of the drug and biologic development process that is often called “the valley of death” (pre-IND through approval) where high costs of studies and high rates of product failure are part of the drug development landscape. Imaging tools can serve in this …
Melt Extrusion
Materials, Technology and Drug Product Design
Av Michael A. Repka, Nigel Langley m. fl.
Häftad, 2016
1692 kr
Lägg i varukorg
This volume provides readers with the basic principles and fundamentals of extrusion technology and a detailed description of the practical applications of a variety of extrusion processes, including various pharma grade extruders. In addition, the downstream production of films, pellets and …
Sterile Product Development
Formulation, Process, Quality and Regulatory Considerations
Av Parag Kolhe, Mrinal Shah m. fl.
Häftad, 2016
3714 kr
Lägg i varukorg
This comprehensive book encompasses various facets of sterile product development. Key concepts relevant to the successful development of sterile products are illustrated through case studies and are covered under three sections in this book:• Formulation approaches that discuss a variety of dosage …
Transporters in Drug Development
Discovery, Optimization, Clinical Study and Regulation
Av Yuichi Sugiyama, Bente Steffansen
Häftad, 2016
1692 kr
Lägg i varukorg
Transporters in Drug Development examines how membrane transporters can be dealt with in academic–industrial drug discovery and pharmaceutical development as well as from a regulatory perspective. The book describes methods and examples of in vitro characterization of single transporters in the …
FDA Bioequivalence Standards
Häftad, 2016
2590 kr
Lägg i varukorg
This comprehensive reference provides an in-depth discussion on state-of-the-art regulatory science in bioequivalence. In sixteen chapters, the volume explores a broad range of topics pertaining to bioequivalence, including its origin and principles, statistical considerations, food effect studies, …
