Chemical Analysis: A Series of Monographs on Analytical Chemistry and Its Applications – serie

In Vivo Glucose Sensing is a key reference for scientists and engineers working on the development of glucose sensing technologies for the management of diabetes and other medical conditions. It discusses the analytical chemistry behind the strategies currently used for measuring glucose in vivo. It focuses on analyzing samples in the real world and discusses the biological complexities that make glucose sensing difficult. Covering current implantable devices, next-generation implantable sensing methods, and non-invasive methods for measuring glucose, this book concludes with an overview of possible applications other than diabetes.

Time of flight mass spectrometry identifies the elements of a compound by subjecting a sample of ions to a strong electrical field. Illuminating emerging analytical techniques in high-resolution mass spectrometry, Liquid Chromatography Time-of-Flight Mass Spectrometry shows readers how to analyze unknown and emerging contaminants—such as antibiotics, steroids, analgesics—using advanced mass spectrometry techniques. The text combines theoretical discussion with concrete examples, making it suitable for analytical chemists, environmental chemists, organic chemists, medicinal chemists, university research chemists, and graduate and post-doctorate students.

Attenuated Total Reflection (ATR) Spectroscopy is now the most frequently used sampling technique for infrared spectroscopy.  This book fully explains the theory and practice of this method. Offers introduction and history of ATR before discussing theoretical aspectsIncludes informative illustrations and theoretical calculationsDiscusses many advanced aspects of ATR, such as depth profiling or orientation studies, and  particular features of reflectance

Presents an overview of applications, a critical evaluation of current techniques for sampling and for obtaining spectra, and an extensive guide to the literature, both spectra and papers. Covers everything from how to prepare almost any kind of sample and how to optimize the controls on an infrared spectrometer, to identifying and measuring pollutants at the parts per million level. Stresses all fundamental concepts and limitations; includes examples of difficulties and pitfalls throughout. Emphasizes development of technique and careful manipulation of samples and spectrometers. Highlights quantitative analysis with examples. Also reviews factors affecting group frequencies.

In the 1960s, the development of inductively coupled plasmas (ICP) as excitation sources for atomic emission spectroscopy (AES) permitted, for the first time, the convenient, simultaneous determination of a number of chemical elements in solutions. In two self-contained volumes, this is the first definitive text/reference on ICP-AES since the introduction of this important analytical technique. Part 1 of Inductively Coupled Plasma Emission Spectroscopy covers the basis of ICP-AES as an analytical method and discusses fundamental analytical concepts, performance, and figures of merit; principles of the instrumentation; the relation between ICP and other modern "plasma sources;" and the connection between ICP-AES, on one hand, and ICP atomic fluorescence spectroscopy and ICP mass spectroscopy, on the other.Part 2 examines applications and fundamentals of the technique. The overall treatment of the subject is tutorial, systematic, and consistent. The approach is scientific and rigorous, but mathematical formulae are used only when they promote clarity. Aside from filling a void in the AES literature, Inductively Coupled Plasma Emission Spectroscopy provides a critical survey of more than 20 years of research, development, and application in the field of ICP and related plasma sources. It is an excellent handbook for both novices and experts, and it serves as an aidememoire and major source of reference for analytical spectroscopists, analytical chemists, physical chemists and physicists, including those who are researchers, technicians, and applied analysts.

In this revised and updated edition of his successful reference, Jungreis shares his expertise with readers to explore the contemporary utilization of simple spot and screening tests in clinical forensic, geochemical, and environmental applications. Its broad range makes it ideal for use in the chemical analysis of food, air, water, forensic studies, and any area where quick, on-the-spot chemical analysis is required. The new edition features the latest techniques in the field.

A complete nuts-and-bolts guide to GFAAS principles, methodology, instrumentation, and applications Graphite Furnace Atomic Absorption Spectrometry is now generally accepted as one of the most reliable methods of measuring quantities of trace elements in biological, clinical, environmental, food, geological, and other samples. Yet, surprisingly, there continues to be a dearth of practical guides and references on the subject. A Practical Guide to Graphite Furnace Atomic Absorption Spectrometry helps to fill that gap by providing chemists with:* Detailed coverage of GFAAS theory and analytical methodology* Descriptions of instrumentation, calibration, and analysis* Step-by-step instructions on how to prepare and introduce samples* Strategies for developing original GFAAS methods for your lab* Practical, in-depth reviews of all commercial instrumentation* A complete guide to the relevant world literature on GFAAS Long considered too unwieldy for most practical purposes, Graphite Furnace Atomic Absorption Spectrometry (GFAAS) is now considered an indispensable tool of analytical chemistry. Thanks to a series of relatively recent instrumental and methodological improvements that make the technique more easy to control, GFAAS is now routinely used for measuring concentrations of many trace elements (all metals and some nonmetals) in biological, clinical, environmental, food, geological, and other samples--especially in cases in which the samples are either too small or in which the analyte concentrations are too low to be measured by flame atomic absorption techniques. A Practical Guide to Graphite Furnace Atomic Absorption Spectrometry is an up-to-date and thorough guide to performing GFAAS. Following a concise introduction to GFAAS theory, nomenclature, and analytical methodology, the authors present a detailed discussion of all practical aspects of GFAAS. In separate chapters they provide in-depth coverage of calibration, instrumentation, interference-free analysis, and sample preparation and introduction. Chapters also examine the types, costs, and training of commercial GFAAS instrumentation, and strategies for developing GFAAS methods tailored to the unique demands of your research pursuits. The book concludes with a series of helpful appendices featuring a fascinating historical account of GFAAS, a guide to relevant literature in the field, and a valuable compilation of conditions for performing GFAAS. A Practical Guide to Graphite Furnace Atomic Absorption Spectrometry belongs in the working libraries of all analytical chemists. Jacket Design/Illustration: Keithley & Associates Inc.

This book concerns the design, operation and application of devices capable of generating acoustic waves in the ultrasonic frequency range. It emphasizes the study of chemical and/or biochemical systems imposed on the surface of such devices, whether operated in the gas- or liquid-phase, i.e. on acoustic wave chemical and biological sensors. It focuses on devices that employ acoustic waves launched and received on the same surface. It touches upon such diverse areas as acoustic wave physics, applied mathematics, chemistry, electronics, fluid mechanics, materials science and polymer science.

A complete and up-to-date manual on HPCE theory and practice High Performance Capillary Electrophoresis brings together in one volume essential coverage of the theory, techniques, and applications of this highly useful and efficient technology. Suitable for the novice as well as the experienced user of HPCE, this book features expert contributions from highly respected scientists representing a wide range of disciplines. Chapters, which are grouped into sections to make information easy to find, cover:* Theory and principles of the six HPCE techniques* Detection systems, including indirect detection* Essential operation topics such as sample introduction and stacking, coated capillaries, and method validation* Recently developed methods, including two-dimensional separations, nonaqueous CE, and HPCE on microchips* All of the basic HPCE applications, with an emphasis on bioanalytical uses* HPCE in the determination of physico-chemical properties of molecules With features and capabilities that match--and even surpass--those of conventional electrophoresis and HPLC, high performance capillary electrophoresis (HPCE) is the fastest developing technology for the separation and analysis of chemical compounds. Keeping pace with the rapid changes in this field and the wealth of journal articles on the subject is a difficult and time-consuming challenge for anyone needing a basic and up-to-date grasp of HPCE. This book makes it much easier to find this important information--with comprehensive one-source coverage of all of the essential aspects of HPCE theory, techniques, and applications. Featuring the contributions of well-qualified, highly regarded scientists, it is organized into sections on:* Theory and principles of HPCE techniques* Detection systems* Operation aspects and special methods in HPCE* Uses in chemical analysis* Physico-chemical studies Specific topics addressed here that are not treated extensively by other books include two-dimensional separations, CE on microchips, nonaqueous CE, indirect detection, monitoring enzymatic reactions, and more. As interest in HPCE continues to grow, it is clear that this technology has much to offer researchers and others working in disciplines ranging from analytical chemistry and biochemistry to pharmaceutical chemistry and biotechnology. High Performance Capillary Electrophoresis equips scientists and students with the knowledge they need to take immediate advantage of the exciting potential of HPCE.

This self-contained book provides modern and practical analytical methodologies for the assays in foods, pharmaceuticals and clinical samples. It covers the fat-soluble Vitamins: A, beta-carotene, D, E and K as well as the water soluble vitamins, C, folate, thiamin, biotin, pyridoxin and cyancobalims.

A bestselling classic reference, now expanded and updated to cover the latest instrumentation, methods, and applications The Second Edition of Fourier Transform Infrared Spectrometry brings this core reference up to date on the uses of FT-IR spectrometers today. The book starts with an in-depth description of the theory and current instrumentation of FT-IR spectrometry, with full chapters devoted to signal-to-noise ratio and photometric accuracy. Many diverse types of sampling techniques and data processing routines, most of which can be performed on even the less expensive instruments, are then described. Extensively updated, the Second Edition:* Discusses improvements in optical components* Features a full chapter on FT Raman Spectrometry* Contains new chapters that focus on different ways of measuring spectra by FT-IR spectrometry, including fourteen chapters on such techniques as microspectroscopy, internal and external reflection, and emission and photoacoustic spectrometry* Includes a new chapter introducing the theory of vibrational spectrometry * Organizes material according to sampling techniques Designed to help practitioners using FT-IR capitalize on the plethora of techniques for modern FT-IR spectrometry and plan their experimental procedures correctly, this is a practical, hands-on reference for chemists and analysts. It's also a great resource for students who need to understand the theory, instrumentation, and applications of FT-IR.

Wavelet Transformations and Their Applications in Chemistry pioneers a new approach to classifying existing chemometric techniques for data analysis in one and two dimensions, using a practical applications approach to illustrating chemical examples and problems. Written in a simple, balanced, applications-based style, the book is geared to both theorists and non-mathematicians.This text emphasizes practical applications in chemistry. It employs straightforward language and examples to show the power of wavelet transforms without overwhelming mathematics, reviews other methods, and compares wavelets with other techniques that provide similar capabilities. It uses examples illustrated in MATLAB codes to assist chemists in developing applications, and includes access to a supplementary Web site providing code and data sets for work examples. Wavelet Transformations and Their Applications in Chemistry will prove essential to professionals and students working in analytical chemistry and process chemistry, as well as physical chemistry, spectroscopy, and statistics.

Owing to its unique combination of high information content and ease of use, Raman spectroscopy, which uses different vibrational energy levels to excite molecules (as opposed to light spectra), has attracted much attention over the past fifteen years. This book covers all aspects of modern Raman spectroscopy, including its growing use in both the laboratory and industrial analysis.

The chemical study of archaeological materialsArchaeological Chemistry, Second Edition is about the application of the chemical sciences to the study of ancient man and his material activities. The text of the book centers on the use of chemical methods, but also refers to the contributions of physics, biology, and genetics to archaeological research.Subjects discussed in the book include the determination of the nature of ancient materials, their provenance and age, the technologies used for the production of man-made materials, and the analysis of ancient human and animal remains (such as bone, dried blood, and coprolites), which yields information on ancient diets, kinship, habitancy, and migratory patterns.New developments in analytical chemistry and in related disciplines, which have contributed to archaeological research since the first edition of the book was published, are dealt with in this edition, which also includes: Updated information on the study of the nature, age, and provenance of ancient materialsNew sections on organic, biological and genetic studiesGlossaryExtensive bibliographyThe book is intended primarily for archaeologists, physical anthropologists and students of archaeology and physical anthropology, but will also be of use to conservators, curators, and art historians. Natural scientists reading it will become acquainted with advances in archaeological research which were made possible only by the application of chemical, physical, and biological methods and techniques.

Quality measurement, control, and improvement in combinatorial chemistryCombinatorial chemistry has developed rapidly in the past decade, with great advances made by scientists working on analysis and purification of a large number of compounds and the analysis of polymer-bound compounds. However, formidable challenges lie ahead of today's researcher. For example, high-throughput analysis and purification technologies must be further developed to ensure combinatorial libraries are "purifiable," and "drugable."To this end, Analysis and Purification Methods in Combinatorial Chemistry describes various analytical techniques and systems for the development, validation, quality control, purification, and physicochemical testing of combinatorial libraries. A new volume in Wiley's Chemical Analysis series, this text has four parts covering:* Various approaches to monitoring reactions on solid support and optimizing reactions for library synthesis* High-throughput analytical methods used to analyze the quality of libraries* High-throughput purification techniques* Analytical methods applied in post-synthesis and post-purification stagesDrawing from the contributions of respected experts in combinatorial chemistry, this comprehensive book provides coverage of applications of Nuclear Magnetic Resonance (NMR), liquid chromatography/mass spectrometry (LC/MS), Fourier Transform Infrared (FTIR), micellar electrokinetic chromatography (MEKC) technologies, as well as other analytical techniques.This eminently useful volume is an essential addition to the library of students and researchers studying or working in analytical chemistry, combinatorial chemistry, medicinal chemistry, organic chemistry, biotechnology, biochemistry, or biophysics.

The use of analytical methods in studies concerning works of art and archaeological artifacts provides essential information on the materials they are made from, including their composition, age, and methods used in their production. This book explains how to use analytical methods to obtain such information.

This new edition of a successful, bestselling book continues to provide you with practical information on the use of statistical methods for solving real-world problems in complex industrial environments. Complete with examples from the chemical and pharmaceutical laboratory and manufacturing areas, this thoroughly updated book clearly demonstrates how to obtain reliable results by choosing the most appropriate experimental design and data evaluation methods.Unlike other books on the subject, Statistical Methods in Analytical Chemistry, Second Edition presents and solves problems in the context of a comprehensive decision-making process under GMP rules: Would you recommend the destruction of a $100,000 batch of product if one of four repeat determinations barely fails the specification limit? How would you prevent this from happening in the first place? Are you sure the calculator you are using is telling the truth? To help you control these situations, the new edition:* Covers univariate, bivariate, and multivariate data* Features case studies from the pharmaceutical and chemical industries demonstrating typical problems analysts encounter and the techniques used to solve them* Offers information on ancillary techniques, including a short introduction to optimization, exploratory data analysis, smoothing and computer simulation, and recapitulation of error propagation* Boasts numerous Excel files and compiled Visual Basic programs-no statistical table lookups required!* Uses Monte Carlo simulation to illustrate the variability inherent in statistically indistinguishable data setsStatistical Methods in Analytical Chemistry, Second Edition is an excellent, one-of-a-kind resource for laboratory scientists and engineers and project managers who need to assess data reliability; QC staff, regulators, and customers who want to frame realistic requirements and specifications; as well as educators looking for real-life experiments and advanced students in chemistry and pharmaceutical science.From the reviews of Statistical Methods in Analytical Chemistry, First Edition:"This book is extremely valuable. The authors supply many very useful programs along with their source code. Thus, the user can check the authenticity of the result and gain a greater understanding of the algorithm from the code. It should be on the bookshelf of every analytical chemist."-Applied Spectroscopy"The authors have compiled an interesting collection of data to illustrate the application of statistical methods . . . including calibrating, setting detection limits, analyzing ANOVA data, analyzing stability data, and determining the influence of error propagation."-Clinical Chemistry"The examples are taken from a chemical/pharmaceutical environment, but serve as convenient vehicles for the discussion of when to use which test, and how to make sense out of the results. While practical use of statistics is the major concern, it is put into perspective, and the reader is urged to use plausibility checks."-Journal of Chemical Education"The discussion of univariate statistical tests is one of the more thorough I have seen in this type of book . . . The treatment of linear regression is also thorough, and a complete set of equations for uncertainty in the results is presented . . . The bibliography is extensive and will serve as a valuable resource for those seeking more information on virtually any topic covered in the book."-Journal of American Chemical Society"This book treats the application of statistics to analytical chemistry in a very practical manner. [It] integrates PC computing power, testing programs, and analytical know-how in the context of good manufacturing practice/good laboratory practice (GMP/GLP) . . .The book is of value in many fields of analytical chemistry and should be available in all relevant libraries."-Chemometrics and Intelligent Laboratory Systems

X-ray fluorescence spectroscopy, one of the most powerful and flexible techniques available for the analysis and characterization of materials today, has gone through major changes during the past decade.Fully revised and expanded by 30%, X-Ray Fluorescence Spectrometry, Second Edition incorporates the latest industrial and scientific trends in all areas. It updates all previous material and adds new chapters on such topics as the history of X-ray fluorescence spectroscopy, the design of X-ray spectrometers, state-of-the-art applications, and X-ray spectra.Ron Jenkins draws on his extensive experience in training and consulting industry professionals for this clear and concise treatment, covering first the basic aspects of X rays, then the methodology of X-ray fluorescence spectroscopy and available instrumentation. He offers a comparison between wavelength and energy dispersive spectrometers as well as step-by-step guidelines to X-ray spectrometric techniques for qualitative and quantitative analysis-from specimen preparation to real-world industrial application.Favored by the American Chemical Society and the International Centre for Diffraction Data, X-Ray Fluorescence Spectrometry, Second Edition is an ideal introduction for newcomers to the field and an invaluable reference for experienced spectroscopists-in chemical analysis, geology, metallurgy, and materials science.An up-to-date review of X-ray spectroscopic techniques. This proven guidebook for industry professionals is thoroughly updated and expanded to reflect advances in X-ray analysis over the last decade. X-Ray Fluorescence Spectrometry, Second Edition includes: The history of X-ray fluorescence spectrometry-new to this edition.A critical review of the most useful X-ray spectrometers.Techniques and procedures for quantitative and qualitative analysis.Modern applications and industrial trends.X-ray spectra-new to this edition.

The importance of accurate sample preparation techniques cannot be overstated--meticulous sample preparation is essential. Often overlooked, it is the midway point where the analytes from the sample matrix are transformed so they are suitable for analysis. Even the best analytical techniques cannot rectify problems generated by sloppy sample pretreatment. Devoted entirely to teaching and reinforcing these necessary pretreatment steps, Sample Preparation Techniques in Analytical Chemistry addresses diverse aspects of this important measurement step. These include:* State-of-the-art extraction techniques for organic and inorganic analytes* Sample preparation in biological measurements* Sample pretreatment in microscopy* Surface enhancement as a sample preparation tool in Raman and IR spectroscopy* Sample concentration and clean-up methods* Quality control steps Designed to serve as a text in an undergraduate or graduate level curriculum, Sample Preparation Techniques in Analytical Chemistry also provides an invaluable reference tool for analytical chemists in the chemical, biological, pharmaceutical, environmental, and materials sciences.

Petroleum exhibits a wide range of physical properties. Numerous tests have been and continue to be developed to provide an indication of the means by which a particular feedstock should be processed. An initial inspection of the nature of petroleum provides deductions about the most logical means of refining and classifying. Handbook of Petroleum Analysis is a single, comprehensive source that describes the application and interpretation of data resulting from various test methods for petroleum feedstocks and products. The need for the application of analytical techniques to petroleum has increased over the past three decades due to changes in feedstock composition. Handbook of Petroleum Analysis deals with the various aspects of petroleum analysis while providing a detailed explanation of the necessary standard tests and procedures that are applicable to feedstocks. The material also reviews the application of new methods for determining instability and incompatibility, focusing on the analytical methods related to environmental regulations. Most importantly, the book provides details of the meanings of the various test results and how they might be applied to predict feedstock behavior. Where pertinent, new tests that are not yet accepted as standardized are described.Topics covered in Handbook of Petroleum Analysis include:- Chemical composition- Physical, thermal, electrical, and optical property testing methods- Spectroscopic, chemical, fractionation, and chromatographic methods- Molecular weight- Use of the data (i.e., mapping and predictability)Handbook of Petroleum Analysis promotes a better understanding of the criteria affecting the quality of petroleum and petroleum products and is a valuable resource for chemists and engineers in the refining industry.

Polycyclic aromatic hydrocarbons (PAHs) are the first type of chemicals that were ever discovered to cause cancer in humans. They are found in cigarette smoke, in barbecued and smoked foods, in automobile and Diesel engine exhaust, fireplace smoke, and many other common things that people are exposed to. Analyzing for PAHs in the environment is important in identifying potential sources of cancer exposure and eliminating these as risks. The smaller PAHs, those of lower than 300 molecular weight, have been the most studied and have also been covered in several books. No books have dealt with the analysis of the larger PAHs. These compounds are not only important for the health concerns, but they are also of current technological and scientific interest.

A definitive reference, completely updated Published in 1989, the First Edition of this book, originally entitled Quadrupole Storage Mass Spectrometry, quickly became the definitive reference in analytical laboratories worldwide. Revised to reflect scientific and technological advances and new applications in the field, the Second Edition includes new chapters covering:* New ion trap instruments of high sensitivity* Peptide analysis by liquid chromatography/ion trap tandem mass spectrometry* Analytical aspects of ion trap mass spectrometry combined with gas chromatography* Simulation of ion trajectories in the ion trap One additional chapter discusses the Rosetta mission, a "comet chaser" that was sent on a ten-year journey in 2004 to study the comet Churyumov-Gerasimenko using, among other instruments, a GC/MS system incorporating a specially designed ion trap mass spectrometer. This comprehensive reference also includes discussions of the history of the quadrupole ion trap, the theory of quadrupole mass spectrometry, the dynamics of ion-trapping chemistry in the quadrupole ion trap, the cylindrical ion trap, miniature traps, and linear ion traps. Complete with conclusions and references, this primer effectively encapsulates the body of knowledge on quadrupole ion trap mass spectrometry. With its concise descriptions of the theory of ion motion and the principles of operation, Quadrupole Ion Trap Mass Spectrometry, Second Edition is ideal for new users of quadrupole devices, as well as for scientists, researchers, and graduate and post-doctoral students working in analytical laboratories.

Planar Chromatography in the Life Sciences Edited by Joseph C.TouchstoneThis assemblage of studies from international researchers inplanar, or thin layer, chromatography describes the many advancesthat have placed the technique so much in the vanguard of materialsanalysis research. Chapters describe currents in planarchromatography; use of bonded phases in planar chromatography;immunostaining in TLC; TLC in pharmaceutical research;determination of ascorbic acid by TLC-densitometry; isotopescanning in TLC; and more. This addition to the outstanding WileySeries in Chemical Analysis is a reference staple for analyticalchemists in academia and industry as well as scientists in relatedfields and students of chemistry and the life sciences. 1990(0-471-50109-3) 199 pp.

Describes the basic prerequisities for a fluorometric immunoassay: the antibody, the immunological technology, the fluorescent probe, and the instrument. Provides a profile of the clinical applications of the various assay technologies. Topics include: background noise, the mechanization and automation of immunoassays, DNA-based specific binding assays, fluorescence immonosensors, multiparameter analyzing systems and more.

When bombarded with X-rays, solid materials produce distinct scattering patterns similar to fingerprints. X-ray powder diffraction is a technique used to fingerprint solid samples, which are then identified and cataloged for future use-much the way the FBI keeps fingerprints on file. The current database of some 70,000 material prints has been put to a broad range of uses, from the analysis of moon rocks to testing drugs for purity. Introduction to X-ray Powder Diffractometry fully updates the achievements in the field over the past fifteen years and provides a much-needed explanation of the state-of-the-art techniques involved in characterizing materials. It covers the latest instruments and methods, with an emphasis on the fundamentals of the diffractometer, its components, alignment, calibration, and automation. The first three chapters outline diffraction theory in clear language, accessible to both students and professionals in chemistry, physics, geology, and materials science. The book's middle chapters describe the instrumentation and procedures used in X-ray diffraction, including X-ray sources, X-ray detection, and production of monochromatic radiation. The chapter devoted to instrument design and calibration is followed by an examination of specimen preparation methods, data collection, and reduction. The final two chapters provide in-depth discussions of qualitative and quantitative analysis. While the material is presented in an orderly progression, beginning with basic concepts and moving on to more complex material, each chapter stands on its own and can be studied independently or used as a professional reference. More than 230 illustrations and tables demonstrate techniques and clarify complex material. Self-contained, timely, and user-friendly, Introduction to X-ray Powder Diffractometry is an enormously useful text and professional reference for analytical chemists, physicists, geologists and materials scientists, and upper-level undergraduate and graduate students in materials science and analytical chemistry. X-ray powder diffraction-a technique that has matured significantly in recent years-is used to identify solid samples and determine their composition by analyzing the so-called "fingerprints" they generate when X-rayed. This unique volume fulfills two major roles: it is the first textbook devoted solely to X-ray powder diffractometry, and the first up-to-date treatment of the subject in 20 years. This timely, authoritative volume features:* Clear, concise descriptions of both theory and practice-including fundamentals of diffraction theory and all aspects of the diffractometer* A treatment that reflects current trends toward automation, covering the newest instrumentation and automation techniques* Coverage of all the most common applications, with special emphasis on qualitative and quantitative analysis* An accessible presentation appropriate for both students and professionals* More than 230 tables and illustrations Introduction to X-ray Powder Diffractometry, a collaboration between two internationally known and respected experts in the field, provides invaluable guidance to anyone using X-ray powder diffractometers and diffractometry in materials science, ceramics, the pharmaceutical industry, and elsewhere.

High Performance Liquid Chromatography in Biotechnology Edited By William S. Hancock Analytical chemists, biochemists, or chemical engineers will find this up-to-date guide to HPLC's recent developments essential to enhancing their on-the-job technical expertise. Extensive coverage includes the broad applications of HPLC, ranging from major chromatographic techniques (including reversed phase, ion exchange, affinity and hydrophobic interaction chromatography) to specific separations such as in monoclonal antibody and nucleic acid purification. The book also highlights the techniques required for a quality control program and such advanced technology as mass spectrometry. 1990 (0 471-82584-0) 576 pp. Unified Separation Science J. Calvin Giddings This advanced text/monograph brings together, for the first time in a single volume, the variety of techniques used for chemical separations by outlining their common underlying mechanisms. The mass transport phenomena underlying all separation processes are developed in a simple physicalmathematical form, facilitating analysis of alternative separation techniques and the factors integral to separation power. The first six chapters provide generic background material applicable to a wide range of separation methods, including the theoretical foundations of separations rooted in transport, flow, and equilibrium phenomena. The final five chapters illustrate specific techniques and methods, including electrophoretic and sedimentation techniques, field-flow fractionation, and chromatography. 1991 (0 471-52089-6) 352 pp.

Over the past three decades, luminescence spectroscopy has transcended its origins as a curiosity in the physical laboratory to become a widely used and respected staple of the analytical chemist's instrumentation arsenal. Fluorescence, chemiluminescence, and phosphorescence spectroscopies are now routinely applied to such real analytical problems as the quantitaion, qualitative identification, and structural characterization of organic and inorganic compounds and even of cellular structures. And the list of recent advances in analytical applications of luminescence spectroscopy keeps growing. The earlier volumes of Molecular Luminescence Spectroscopy provided professional chemists with a detailed, exhaustive, and up-to-date look at the applications of fluorescence, phosphorescence, and chemiluminescence spectra to the analysis of organic and inorganic compounds. Presenting topics never available in any analytical text, such as excited state optical activity and bioinorganic luminescence spectroscopy, the volumes represented a significant advance in the chemical literature. Part 3 continues the book's always current and practical examination of the field’s newest innovative turns. In a clear, systematic format, Part 3 discusses such widespread or ascendant laboratory techniques as: photochemically generated fluorophoresfluorescent probesluminescence from bile salt aggregateshole-burning spectroscopylaser-excited microspectro-fluorometrynear-infrared luminescence spectroscopyOther topics such as the fluorescence and phosphorescence of pharmaceuticals and natural products have never been reviewed as exhaustively before. The chapters on fluorescence detection in chromatography and luminescence immunoassay are the most up-to-date treatments available on these subjects. Invaluable to analytical chemists, instructors, and students, Molecular Luminescence Spectroscopy, Part 3 offers expert guidance on the practical specifics of this multi-faceted technique as well as its farreaching analytical possibilities.

High-Resolution Solid-State NMR of Silicates and Zeolites Gunter Engelhardt and Dieter Michel "I strongly recommend this book as an important reference for scientists concerned with the structural properties of siliceous materials." --Applied Spectroscopy This well-organized and up-to-date text gives a thorough account of the wide range of applications of multinuclear high-resolution solid-state NMR spectroscopy in silicate and zeolite science, with emphasis on the kinds of chemical information retrievable from NMR experiments. 1988 (0 471-91597-1) 485 pp. The Chemistry of Silica Solubility, Polymerization, Colloid and Surface Properties, and Biochemistry Ralph K. Iler A major component of the earth's solid surface and the constituent of sand, silica--an ageless natural staple--is also integral to industries as diverse as chemistry, biology, medicine, agriculture, metallurgy, and mining. This landmark reference details the chemistry surrounding the research and development of silica as well as information on its production and production control. 1979 (0 471-02404-X) 866 pp. The Chemistry of Organic Silicon Compounds Parts 1 and 2 Edited by Saul Patai and Zvi Rappoport "This volume will probably become the first reference consulted for C-Si chemistry." --Choice This authoritative account of organic compounds containing carbon-silicon bonds brings specialists up-to-date to the field's latest innovative turns. The emphasis in this compilation of studies--from 17 prominent researchers--is on small molecules, single bonds, analysis, structure, synthesis, spectroscopy, and reaction mechanisms. Part 1:1989 (0 471-91441-X) 892 pp. Part 2:1989 (0 471-91992-6) 1,668 pp.

Examines fluorescence spectrometry with special emphasis on its applications to biochemistry. Fluorescence techniques are particularly useful because of their very high sensitivity and selectivity, especially when used in connection with chemical techniques for forming fluorescent derivatives. HPLC techniques are incorporated throughout and the utility of fluorescence when coupled with HPLC is explored.