In Clinical Practice – serie

Sickle Cell Disease is the most common genetic disease world wide and in the UK. It has marked geographical variation in its distribution in the UK, with a concentration in London and other major conurbations (Birmingham and Manchester). In these areas, specialist centres have become established offering expert, up to date care for both inpatients and out patients with Sickle Cell Disease. Although patient numbers are increasing outside these areas, the expertise of health professionals can be patchy. This book aims to provide a user friendly, accessible resource for areas with smaller numbers of patients, to allow them to provide equitable care with the larger well established centres. Sickle Cell Disease can be associated with acute life threatening complications, when clear, easily available advice is needed, and with chronic long term complications which may need liaison with other health professionals. Clear treatment protocols for all the common complications of sickle cell disease, are outlined here, with summaries of key evidence and references.

This compact pocketbook provides orthopaedic surgeons in training with concise and relevant core knowledge on all aspects of children’s fractures. Content includes the common fractures that affect children and “Red flags”, such as the key management points of potentially serious injuries and complications. This book would also be useful to pediatricians and Accident & Emergency department doctors working in busy clinics that need a quick reference guide and with highlighted “red flags” of children’s fractures.It is vital that anyone training in orthopaedics is well versed in the art and practice of orthopaedic trauma. Paediatric orthopaedic trauma presents its own unique challenges, from the assessment of the injured child (and management of the parents and extended family) through to intervention with minimal complication and follow-up for long-term complications. The aim of this book is to cover all the major aspects of paediatric orthopaedic trauma and to ease the passagethrough examinations, such as the FRCS(Orth), and busy on-calls, where common children's fractures are frequently encountered.

This book provides orthopaedic surgeons in training with concise and relevant core knowledge on all aspects of children’s orthopaedics. Content includes the common orthopaedic conditions that affect children, and key management points in each chapter are highlighted for readers to quickly access this information. The aim of this resource is to offer an authoritative guide on all facets of children’s orthopaedics so the treating doctor has enough information to confidently allay the anxieties of the patient and their parents, and to identify when to refer the child to a paediatric orthopaedic surgeon. This book will be an essential reference guide for newly qualified orthopaedic specialists, as well as paediatricians and family doctors working in busy clinics that treat children who present with orthopaedic conditions.

This book provides insights into sports medicine addressing trauma of the hand and wrist. This collection of injuries invites readers to trace aetiology, diagnosis, relevant pathology, management principles, and outcomes of numerous injuries in elite and non-elite athletes. The authors present management principles and outcomes. It is an ideal reference for postgraduate musculoskeletal doctors and therapists for Orthopaedic and Sports Medicine postgraduate degrees. Each approach to deal with an injury is underlined by case reports. Readers will also find valuable questions and answers fro self-assessment purpose. Sports Injuries of the Hand and Wrist is aimed at sports doctors, musculoskeletal doctors, senior orthopedic trainees with an interest in upper limb, orthopedic trainees preparing for the FRCSOrth exam and similar international exams, as well as upper hand and wrist surgeons in the earlier years of their practice.

This book comprehensively covers hand trauma from initial presentation to management. Material is presented in an easy to follow practically applicable way, bridging the gap between what trainees encounter during training and what is encountered in a busy emergency department . Topics covered include upper limb anatomy, soft tissue injuries and infections, hand fractures, anaesthesia, and referrals from primary care, with detailed guides provided on how to successfully perform techniques such as digit replantation, extravasation, and locoregional flaps.  Hand Trauma in Clinical Practice systematically describes a variety of categories of hand trauma, and plastic and orthopaedic surgical techniques. Therefore, it represents a valuable resource for practising and trainee plastic surgeons, orthopaedic surgeons, and emergency care specialists.

This updated second edition provides a concise and up-to-date guide to emergency brain CT scans. Revised illustrations and images are included to assist readers in understanding key concepts in a clear way. The use of brain CT scans by health care professionals is increasingly common and has been effective in the minimising of costs and the unnecessary transfer of traumatic brain injury patients.The book aims to give nurses, emergency room physicians, primary care physicians, and doctors the information and tools needed to examine CT scans and explain them to their patients. With this knowledge emergency physicians and trauma surgeons will be able to decide whether an injury is life threatening.

This practical guide provides a full but concise account of the organ donation and transplantation process, from the management of the donor and organ preservation to perioperative management and surgical techniques.Readers will learn about various aspects of multi-organ retrieval such as different types of donors and evaluation of organ donors, as well as the retrieval process itself and ethical aspects of transplantation. Written in a consistent format, each of the themed parts examines the different types of solid organ transplantation, namely kindey, pancreas and liver. Each part discusses the indications for transplantation, organ allocation, surgical technique, post-operative management outcomes and professional skills for the surgeon. This is an essential guide for the transplant surgeon offering a unique summary of the critical issues in abdominal organ transplantation.

This book comprehensively covers the latest consensus in the diagnosis and management of patients with recurrent Urinary Tract Infections (UTIs). It features a broad overview of the basic science and the spread of antibiotic resistance in UTIs. Guidelines are provided on the recommended approaches for using antibiotics including dosage, duration, resistance rates for a range of antibiotics, and available methods for combating antibiotic resistance. Further topics covered include prophylaxis, including conservative lifestyle modifications as well as preventative therapies.  Female Urinary Tract Infections in Clinical Practice summarises the basic science, use of antibiotics, and preventative strategies for UTIs and represents a timely and valuable resource for all practising and trainee medical professionals who encounter these patients in their practice.

This book discusses the most common symptoms in pediatrics. It is based on best available scientific evidence and up-to-date information. The book also discusses a range of common conditions associated with bacterial and viral infections of the oro-nasal, eye, chest, abdominal and genito-urinary regions. The book helps the clinician to distinguish symptoms andsigns of pediatric diseases to avoid diagnostic errors. Each chapter starts with a list of core messages, and includes tables and figures  to focus on the subjects under discussion. The whole text is written in reader-friendly manner. The book is of interest to general pediatricians and doctors in primary care. It is also of interest to students, nurses and other professionals who look after children.

This book provides a concise, step-by-step guide to accurate microscopic diagnosis for clinicians who deal with patients with breast lesions. The emphasis is on a practical approach to dealing with breast biopsies and reaching a diagnosis. It outlines the procedures used for the microscopic diagnosis of various breast lesions and the significance of the nomenclature and terms used in pathology reports, including those dealing with uncommon or rare lesions. Ample illustrations of the lesions discussed are included, particularly those dealing with uncommon and border-line lesions. There is a special emphasis on breast cancer and on the fact that not all breast cancers are the same. The different ways by which breast cancers are classified are discussed including recent classifications which lead to personalized therapy. The book is aimed at pathologists of all grades who deal with breast biopsies including those in training. It would be also useful for practicing and trainee surgeons and oncologists as well as other health professionals dealing with patients with breast diseases and scientists carrying out research on breast problems.

This book provides a practical guide for managing a variety of problems encountered by the clinician in managing patients with systemic sclerosis. Chapters take a problem-orientated approach to help the reader cut through potential barriers that can arise when working with different medical specialities. Management strategies for a broad range of conditions, including pericardial and pleural effusion, sicca syndrome, calcinosis and watermelon stomach, are presented.  ​Practical Management of Systemic Sclerosis in Clinical Practice describes a range of problems and clinical items encountered by a variety of medical professionals who encounter these patients. It is a valuable resource for rheumatologists, immunologists, specialist nurses and primary care professionals.

This book is clearly structured into easy ascending steps. It starts with basic principles of physiology and then goes on to discuss topics such as hypoxia, the A-a gradient, respiratory failure, types of respiratory acidoses and their compensation. Concise and easy to follow chapters examine complex disorders of metabolic acidosis and alkalosis with examples and case reports to stimulate thoughts of the readers. Pearls of clinical wisdom are spread throughout each chapter of the book.   Arterial Blood Gas Interpretation in Clinical Practice is intended for all trainees and clinicians in emergency medicine, acute medicine, intensivism, respiratory medicine, nephrology, cardiology, anaesthesia, paediatrics, internal medicine, general medicine and endocrinology. It is particularly useful to medical students and nurses working in the specialties above. Physiologists and physiotherapists working in ventilator support, will also be highly benefitted with this title.

This book assesses the main features of COVID-19 from a clinical point of view, based on observations made during the disease epidemic in Northern Italy, one of the most affected areas in the world (the region has been the epicenter of the global pandemic for more than a month), and the first region outside China facing overwhelming numbers of cases. With no practical guidelines in place, Italian doctors were called to fight against an unknown disease. For the first time in modern history, healthcare workers and decision-makers had to find rapid solutions to a life-changing health crisis with no evidence-based recommendations or procedures in place to guide their actions. Sharing the lessons learned from this experience, and offering practical tips on implementing future programs for pandemic preparedness, the book is a valuable tool for medical practitioners and health-policy-makers wanting to better understand the complexity of the current and future global health crises.

This book concisely summarizes the use of Botulinum neurotoxin in facial rejuvenation. It details relevant aspects of the physiology, pharmacology, safety profile and anatomy of the toxin. Chapters breakdown critical aspects related to the clinical assessment and aesthetic administration of this neurotoxin along with insightful information on its regulation.    Botulinum Toxin in Clinical Practice provides a practically focused introductory text to the cosmetic applications of this neurotoxin in aesthetic dermatology, making it an ideal resource for the trainee practitioner seeking a concise summary of the topic.

The book is needed for several reasons. Bariatric surgery is one of the most clinically effective and cost effective services in any field of medicine, and is growing in popularity, and the non-specialist family practitioner, allied health professional and pharmacist need to know exactly what it involves. Bariatric surgery is in everyone’s interest – whether medic or patient, as it offers improvement in diabetes, heart disease, sleep apnoea, fatty liver and many cancers, whilst reducing benefits, housing costs and the general burden on the economy. There is a lot of flawed thinking on surgery in primary care, with only a minority of family practitioner specialists making the majority of referrals, whilst many are denying their patients access because of their own misconceived ideas. A ‘back to basics’ book will help tackle the negative views surrounding the topic, and improve the volume and quality of referrals. Very often patients turning up to obesity centres have been given poor advice, and inappropriate treatment, and arrive with little or no idea what to expect.  Many medics prioritise other conditions first, overlooking the underlying cause, i.e. obesity. Basic education on obesity and co-morbidities is fast becoming essential.

This book provides a concise overview of several critically important techniques and their applications within Laparoscopic Common Bile Duct Exploration (LCBDE).  LCBDE is rapidly emerging as the preferential management option for treating patients with common bile duct (CBD) stones. Chapters within this book describe how this technique can be applied to manage patients with concomitant gallstones, which aims to increase the exploration of the CBD via the transcystic route. Particular mention is made for the use of energy devices to enable stone fragmentation within the bile duct also known as Lithotripsy-Assisted Bile duct Exploration by Laparoendoscopy (LABEL). Guidance is also provided on how to set-up an acute biliary service which can offer the single-stage management of concomitant gallstones and choledocholithiasis. The concepts of ‘Leveraging Access to Technology and Enhanced Surgical Techniques (LATEST)’ in LCBDE and ‘Biliary Surgery 2.0’ as the framework through whichthese techniques can be further enhanced are analysed. Laparoscopic Common Bile Duct Exploration features insight into how to perform these increasingly important procedures successfully and set-up a service within institutions that are yet to provide it. Therefore, it is a valuable resource for all medical professionals involved in the care of these patients.

This book provides cutting-edge information on the vaccination of children treated with various immunosuppressive regimens. The latest literature and recommendations on vaccination in immunosuppressed children are discussed in detail, providing practical guidelines on vaccination for specialists caring for immunosuppressive paediatric patients.Vaccination of Immunosuppressed Children in Clinical Practice is a clinically-focused synthesis for a wide audience of paediatricians around the world. Paediatricians (including rheumatologists, gastroenterologists, immunologists, neurologists, nephrologists, oncologists, haematologists) will find this book to be an essential resource for their daily clinical practice.

The new edition of this pocket guide has been fully updated to cover the common manifestations of liver disease, how to treat them and when to refer patients on to specialist centers.  New chapters on Acute Liver Failure, Nutrition and Congenital Heart Disease have been added to reflect the key issues in management of liver diseases. The book outlines the common clinical liver diseases such as fatty liver disease and viral hepatitis, among others, and their current up to date management.  Written by experts in the field and containing figures and tables, as well as case histories and questions, this is an enjoyable and reader-friendly book for the busy physician. With its authoritative, didactic style and short chapters, it covers the common presentations and complications of liver disease, and how to deal with them.      Given the increasing prevalence of liver disease in the UK and Worldwide, this is an ideal reference book for primary care physicians, doctors in specialist training, clinical nurse specialists and for gastroenterologists, who see patients with liver disease in their working lives.

This book provides a simplified guide to history taking by assessing each symptom in detail, highlighting what key questions are important to ask, and which key differentials are essential to rule out. The chapters are well presented and organised in a logical manner, utilising an easily accessible and user-friendly format for solid learning on focused history taking that includes both general and specific information gathering. History Taking in Clinical Practice includes case-based examples throughout as well as short exercises to enhance learning. GPs, junior doctors and medical students seeking an effective approach to history taking will find this book to be an essential resource for daily clinical practice and exam preparation.

This book provides a clear and concise guide to hypermobility in medicine and physiotherapy. Each chapter is written with a uniform style, including illustrations highlighting the clinical characteristics of manifestations related to hypermobility. Key topics are comprehensively covered throughout the book in the context of both medicine and  physiotherapy. This book offers supportive information for practitioners who are seeking as single resource on the topic. Medical professionals, physiotherapists, physical educators, psychologists, nutritionists, occupational therapists, psychomotor therapists, and postgraduate students will find this book to be an essential guide in their daily clinical practice and research in the field.

This book provides a concise, practical guide to the management of endophthalmitis for busy ophthalmic clinicians. It includes many tips, tricks, clinical pearls and colour photographs to illustrate various aspects of diagnosis that can be quickly referred to when assessing patients. Endophthalmitis in Clinical Practice, 2nd Edition utilises an easy-to-follow ‘cookbook’ style to ensure that information can be rapidly and efficiently obtained for the best possible care of patients with endophthalmitis. In addition to the concise writing style, the compact size of this book means that it can be kept in an on-call bag and can be easily consulted to in clinical practice. New topics in this second edition include the role of systemic antibiotics, steroids in the management of endophthalmitis, non-infectious inflammation, endoscopic vitrectomy as well as updates on infectious keratitis associated endophthalmitis including the roles of photodynamic therapy and microbial diagnostics.

This extensively updated edition is a practical guide to the clinical diagnosis and treatment of cardiac arrhythmias that meets the needs of this highly specialized, complex and growing field of cardiology. As understanding of the evaluation of treatment of arrhythmias continues to advance at a rapid pace, learning and understanding the principles of electrophysiology in order to provide the best possible treatments for patients can be a daunting task.With a scientific, practical and multi-disciplinary approach, Cardiac Electrophysiology in Clinical Practice establishes the foundation of the subject and provides a concise illustrative approach to facilitate and enhance understanding. It is designed to be accessible to serve as an introduction to electrophysiology, but advanced enough to serve as a guide for experienced practitioners. Electrophysiology students of all levels, including residents, fellows, mid-level providers, nurses, technologists, primary care providers, cardiologists and electrophysiologists will find value in these pages.

The book provides a condensed overview of the diagnostics, genetics and current treatment options for congenital corneal opacities and dysgenesis of the anterior segment of the eye. Concise yet detailed presentation of the most important clinical congenital corneal opacities and their differential diagnoses including color illustrations are depicted throughout the book.Diagnosis and Surgical Therapy of Infantile Corneal Opacities includes up-to-date and scientifically reviewed therapy options for specific congenital corneal diseases. Ophthalmologists seeking a clear and concise congenital corneal disease reference guide will find this book to be an indispensable resource in their daily clinical practice.

This new second edition presents a completely new selection of 25 scenarios based on cases from the personal archive of Ondrej Dolezal, collected over 20 years of clinical practice. With a simple and uniquely innovative approach, this book offers a natural workflow through the chapter structure, helping junior doctors to gain confidence in reaching their clinical diagnosis. A range of different clinical scenarios and neurological conditions are examined, from cerebal palsy and other degenerative disorders, to epilepsy and headache. This book can serve as a teaching aid in a classroom setting, where the teacher introduces the case (“telling the story”, neurological examination) and the students then propose differential diagnoses and further tests. The teacher can show a representative test result to students and expect them to interpret the scan/test, as well as proposing further referrals and discussing the prognosis. Each chapter, contains visual aids in the form of Neuroexam, helping the reader gain a quick understanding of the case.Scenarios presented in this book can be used at the bedside in teaching medical students and junior doctors, and it is aimed at trainee neurologists and any non-neurologists who might encounter neurological cases in the clinic.

There is a very large body of literature on Necrotising Enterocolitis (NEC), much of it is confusing and contradictory. This book consolidates all the relevant aspects to provide clinicians and especially trainees with an overview of this condition which informs clinical practice and aids critical appraisal of new research in this area.The topic of NEC is often a single chapter in a paediatric surgical or neonatology text. This book is an invaluable guide for anyone caring for neonates.

This concise guide takes a practical approach to adolescent and young adult (AYA) rheumatology, encompassing the needs of any healthcare professional working with young people aged 10-24 years. Each chapter contains key management points for readers to readily access disease-specific management, as well as highlighting specific AYA issues and approaches which differ from paediatric and adult practice.Adolescent and Young Adult Rheumatology In Clinical Practice, 2nd Edition has been fully revised with the latest research and clinical findings in the field. The coverage in the book is comprehensive but concise and devised to act as a primary reference tool for  AYA practice across the field of rheumatology. The book is designed for paediatric/adult rheumatologists, primary care physicians, nurses and allied health professionals to increase understanding of AYA related topics   and enhance the delivery of developmentally appropriate rheumatology health care.

This book provides a practical overview of the clinical and scientific knowledge relevant to the respiratory physiology of the newborn infant. Clear and concise chapters examine topics such as the mechanics of breathing, the neonatal respiratory system at critical extremes and lung function tests in neonates.Clinical Respiratory Physiology of the Newborn is an indispensable resource for fellows in neonatology and paediatric intensive care as well as senior consultants within the same specialities seeking a complete bedside guide to this evolving topic in clinical practice.

Therapeutic plasma exchange has become an essential tool in modern clinical practice, offering effective treatment for an expanding range of diseases. This book provides a clear and comprehensive guide to the fundamentals of plasma exchange, alongside advanced techniques such as immunoadsorption and LDL apheresis.Recognizing the critical role of immunosuppression in plasma exchange, the text explores the integration of established and novel immunosuppressive therapies. It outlines current indications across multiple specialties—including nephrology, neurology, hematology, rheumatology, and intensive care—and evaluates the latest evidence on clinical outcomes.Readers will find detailed discussion of international guidelines from leading organizations such as ASFA, KDIGO, and the American College of Rheumatology. The book also addresses emerging applications in oncology and highlights future directions for research and practice.Designed for nephrologists, rheumatologists, neurologists, hematologists, and intensive care professionals, this resource combines authoritative guidance with a consistent structure for ease of use. It is an indispensable reference for clinicians seeking to enhance their expertise in plasma exchange and stay aligned with the most recent standards in the field.

This is a well-curated pictorial presentation of common anatomical variants that radiologists encounter in their day to day clinical practice organised by body system. Each variant is accompanied by images from multiple modalities including plain radiography, fluoroscopy, digital subtraction angiography, ultrasonography, computed tomography and magnetic resonance imaging where relevant. The images are clearly labelled and annotated with a brief text description to provide context and tips to avoid common pitfalls in clinical practice. Whilst targeted at radiology trainees preparing to sit for the First FRCR Anatomy examination, the book will also serve as a ready-reckoner for practising radiologists and clinicians from other specialities who review imaging.