Scion Publishing – serie

Clinical Biochemistry, second edition, is essential reading for all students studying clinical biochemistry, especially those on biomedical science courses. The book concentrates on the areas of body function required for the maintenance of health. These include: inputcontrolprocessingtransport and storagedefence and output Each chapter provides an introduction to pathophysiology; how biochemical changes arise as a result of disease processes. The book also describes the important methods used in clinical biochemistry laboratories to show how biochemical changes are measured and how they change during disease. This edition has been substantially revised to incorporate the latest developments in genomics, proteomics and biosensors. The book also benefits from an improved design and layout to aid student understanding.

Protein expression is an increasingly important tool for research on gene function. What is needed is not just a lab manual providing established methods as well as the latest state-of-the-art protocols, but also clear advice on what expression system to choose when. Expression Systems: Methods Express uniquely fills this need. It covers expression across a broad range of systems, including the following:Baculovirus expression vectorsCHO cellsE. coliHEK293-EBNA1 cellsLactococcus lactis and other gram positive bacteriaS. cerevisiaeTransfected insect cellsPichia pastorisMammalian cells using BacMam virusesLentiviral vectorsWheat germ cell-free systemThe book takes the reader through how to make an informed choice of appropriate system, taking into account the protein target, the time involved, the ultimate use of the expressed protein, and the laboratory equipment required. It also provides step-by-step methods for each system. In addition, the book describes the optimisation of expression strategies, expression engineering using ribosome display, and how to select protein variants with improved expression.Every chapter discusses the merits and limitations of the approaches available, describes the key techniques in full practical detail, and provides sensible advice for immediate use at the bench.In summary, Expression Systems: Methods Express is a comprehensive laboratory manual and information resource for researchers at all levels, from postgraduate student to principal investigator.

Anatomy and Physiology in Healthcare focuses on what healthcare students need to know about the biological principles which underpin the practice of healthcare.All healthcare students have to study anatomy and physiology. They often find it a challenging subject and struggle to see how the subject will link to their professional practice.This book is unique in that it integrates clinical cases with the essential biological facts to provide all students with a thorough understanding of how anatomy and physiology can be applied in healthcare.By using clinical cases throughout , the book helps the reader grasp the practical relevance of anatomy and physiology to decision-making and care delivery.The clinical cases have been carefully selected to reflect common conditions encountered in practice today, and the changing patterns of disease and healthcare.Clear high-quality full colour illustrations, links to appropriate web-based content, and self-assessment material make this the perfect, practical textbook for all healthcare students.Review:"This textbook presents anatomy and physiology in a fun and interactive way.... It is divided into 14 chapters and the way the authors have introduced the information gives it a modern twist. For example, instead of titling a chapter 'The reproductive system', it is called 'From one generation to the next'. ..... What works particularly well is the way the authors have used case studies that reflect the reality of the changing patterns of health and disease.... This book provides a good foundation in clinical application and it seeks to link theory to practice."; Nursing Standard, 27 September 2017, volume 32 number 5

Highly commended in the Anaesthesia category of the 2014 BMA Medical Books awards!From reviews:"Altogether, this textbook offers an excellent detailed overview of basic principles, mechanics, and physics of technical equipment used in anaesthesia and intensive care medicine." Critical Care, Feb 2014"This book is excellent. I have read a number of equipment related books and found most of them stale and filled with minutia. Instead this fresh look at equipment really makes it interesting to read and keeps your attention. With sections that give quick answers to how things work, advantages and disadvantages, in an easy to read format you get exactly what you want to know RIGHT away. In addition the full color photos and well done charts really add to the depth of this book.It is my opinion this may be one of the best books on the market for quick review of anesthesia and critical care equipment. Let's be honest, no one is sitting at home reading equipment books for pleasure so when you NEED the information you likely need it right away. This book does exactly that; easy format, clear and concise information with everything you need to know about a piece of equipment easy to find and within a page or two. I would recommend this to all trainees in anesthesia but also for those providers who like to be prepared in the operating room to deal with any issue that might arise." www.nurse-anesthesia.org, 8 Feb 2014Equipment in Anaesthesia and Critical Care specifically follows the syllabus published by the Royal College of Anaesthetists and is the perfect guide for candidates studying for their FRCA qualifications.The book is beautifully illustrated and features high quality colour photographs throughout. The text is engaging and comprehensive, relating each piece of equipment back to its basic physics, mechanics and clinical context. The clear, concise and standardised format means that information is easy to access and perfect for revision. Every major piece of equipment is featured alongside colour photos, reproducible line diagrams, and information on its uses, how it works, pros and cons, and safety considerations.The authors, all senior registrars in anaesthesia and critical care, appreciate exactly what candidates need to know to pass the FRCA exam. They have identified and tackled difficult subjects which are often glossed over or omitted in other resources, to produce a book that is comprehensive, engaging and to the point. In addition to FRCA candidates, the book is also suitable for operating department practitioners, critical care staff, and physicians with an interest in anaesthesia or critical care.

Paediatrics: a clinical handbook provides all the essential information required for a successful paediatrics rotation. Written by two recently qualified junior doctors and a consultant paediatrician, the book offers an exam-centred, reader-friendly style backed up with concise clinical guidance. Building on the success of the other ‘Clinical Handbook’ titles (Rheumatology and Psychiatry), Paediatrics: a clinical handbook provides reader-friendly coverage of the subject in an attractive full-colour design. To help the reader get to grips with the subject quickly and easily, the book features a wide variety of learning aids including mnemonics, numerous clinical photos, OSCE tips, red flag boxes and rapid diagnosis boxes. Paediatrics: a clinical handbook is ideal for medical students and junior doctors; like the other books in the series it will also appeal to medics who want a quick refresher of the subject. Self-assessment tests, in the form of 20 Short Answer questions and 40 Single Best Answer Questions, are available at: www.scionpublishing.com/Paediatrics

This latest edition has been comprehensively updated to include new information on the latest clinical evidence, national guidelines, and from the recent medical literature:all existing cases have been revisednew cases have been added to cover pre-diabetes and premature ejaculationpsoriasis, sore throat, thyroid disease and the PSA test are covered in even more detailThe first three editions have helped thousands of candidates through the CSA exam. The original approach has therefore been retained so the book continues to offer readers a concise ‘need-to-know’ guide to passing the CSA, with the emphasis on successfully completing a case in the allotted ten minutes using a structured consultation framework that works.The aim of the book is to leave exam candidates with more time to concentrate on passing the CSA exam itself.

An innovative, visual textbook for medical students to help learn and understand core medical conditions.Over 100 mind maps:The book features over 100 easy to follow, full colour mind maps of clinically relevant medical conditions using a systems-based structure:CardiologyRespiratoryGastroenterologyRenalEndocrinologyNeurologyRheumatologyInfectious diseasesThe mind maps give you quick access to key information in a visually appealing way. Where appropriate the mind map is followed by additional reference information to remind you about, for example, risk assessment tools, staging criteria, and treatment algorithms. Consistent structure:All mind maps are presented consistently and cover:DefinitionPathophysiologyCauses and Risk factorsClinical features: signs and symptomsEpidemiologyInvestigations: blood tests and imagingManagement: lifestyle, pharmacological and surgicalComplicationsOther key features:Images are provided throughout the book to help illustrate key signs.Mnemonics are used throughout to aid learning.Information is up-to-date and based around the latest guidelines.All topics are clinically relevant or likely to appear in medical school examinations.Mind Maps for Medicine is a key medical textbook for all medical students but particularly those who consider themselves visual learners.

CSA Revision Notes for the MRCGP is the ideal book to help you to revise and prepare for the CSA part of the MRCGP exam. The latest edition features new material on:Constipation in adultsCoughDupuytren’s contractureEating disordersFrailty assessmentGender dysphoriaGoutInguinal herniaPrediabetesStarting HRTVaricose veinsVisual loss A standardised format is used throughout to help you to improve your:data gathering – a broad range of appropriate questions to ask the patient are provided and red flags are highlighted where appropriateinterpersonal skills – each clinical problem is described using terms that you can use in your explanations to patientsclinical management – tells you which examinations to consider, which investigations to order, and how to manage each clinical problem based on the latest guidelines and current best practiceconsultations – to help you practise, every clinical case features a realistic role play scenario.

A new and creative way of thinking about the consultation in primary care, for both trainees and practising GPsThe book features a unique Two Houses model to help the reader move away from completing a series of tasks to focusing on the two key objectives at the heart of every consultation:Working out what matters (The House of Discovery)Deciding with the patient what to do about it (The House of Decision) Using the rich metaphors contained within these houses, the book explores common pitfalls that can beset those who are learning the craft of consulting in primary care, and encourages the reader to fill their toolbox with the skills needed to develop their own patient-centred consultation style.The GP Consultation Reimagined is based on the author's experience of teaching communication skills over 10 years as a GP Training Programme Director. "This book will not teach you to improve your consultations. That is its great merit. Instead, it will encourage you to learn how to consult better." From the Foreword by Roger Neighbour

Clinical Cases Explained! - ideal for Problem-Based Learning coursesClinical Integration: Medicine features 100 clinical cases, with detailed explanations and notes, to help medical students and junior doctors link basic medical science with clinical context and build an appreciation of how pathophysiology manifests as recognisable clues.The book shows readers the logical connections between patient history, examination findings, investigation results, management rationale and their underlying mechanisms. Readers learn to understand the “why and how” behind the diagnosis, investigation and management of common clinical problems. The book uses a system-based approach to cover 100 clinical cases, from aortic dissection to urinary tract infections, via dementia and pneumothorax. Every case uses a consistent format to:highlight the key elements of the history, examination, investigation and treatment phases of medical practiceprovide rapid access to important factsexplore the links between pathophysiology and clinical clues that underpin common medical conditions

Case-based learning is a fundamental part of teaching at medical school because it links theory to practice. Case-Based Discussions in Medicine is designed to help prepare students for clinical practice by working through authentic cases. This updated edition has been revised to reflect recent changes in guidelines.All cases are presented in a consistent style, and cover:history of presenting complaintexamination and interpretationdifferential diagnosesinvestigationsdiagnosis and managementEach case concludes with background information covering the pathophysiology, diagnostic criteria and clinical guidelines.The book is a study companion for medical students and foundation doctors and will help you:become proficient at writing up a patient’s history and examination findingsimprove your clinical decision-making and patient managementbuild your clinical knowledgeFrom back pain and breathlessness to post-partum psychosis, via abdominal pain and jaundice, placenta praevia, and alcoholic liver disease, the book guides you through common cases in medicine, surgery, obstetrics and gynaecology, paediatrics and psychiatry.

A one-stop full-colour resource which provides tailored, guideline-specific information to prepare you for your medical school examinations.Bare Bones Anaesthesia is an exciting new text appropriate for the level of a medical student to excel in their medical school examinations. It contains all the core information you need to know and includes important MCQ and OSCE tips for those tricky situations that examiners attempt to catch medical students out on. These are highlighted throughout the textbook to emphasize their importance for your learning and to focus your understanding.Written by a team of junior doctors, who have recently been through medical schools, the book gives you the essential information in an easy-to-use format.

Three complete mock exams, with answers, including the new-style CRQsCRQs and SBAs for the Final FRCA combines CRQ (constructed response questions) with SBA (single best answer) questions to accurately mimic the structure and content of the new-style final FRCA exam.The book is split into three mock exams, each comprising:12 CRQ with 60 SBA questionsdetailed explanatory answersuseful references to articles to allow readers to improve their knowledgean indication as to the degree of difficulty of each question.The book is ideal for all candidates preparing to sit the final FRCA.

From reviews of the previous editions:“Amazing book. The content is clear, and the recent guidelines are there!”Acute Medicine is a current and concise guide to hospital emergency medicine for registrars, junior doctors and medical students working on the wards. This new edition has been comprehensively revised and updated to incorporate the latest treatment guidelines.It has been substantially rewritten and streamlined to enable the reader to access the pertinent information even more quickly.It is not just a list of instructions, but contains pathophysiology and useful clinical pearls:detailed management of acute medical and surgical emergencies, including in pregnancygeneral ward management issuesdescriptions of key proceduresnormal laboratory valuesemergency drug formularyMore reviews of the previous editions“… a fantastic text for any doctor regardless of their grade. The book covers a huge array of pathology and knowledge in a succinct and accessible way with easy to use chapters with superb explanations throughout. This book is an essential text for all junior doctors.”“I can with complete confidence recommend this book to any hospital physician or trainee. It is infused with useful tips dispensed throughout the text which uniquely (compared to other texts) places you in the mindset of a senior medical registrar or consultant on take.”“This book provides a fantastic overview of a huge range of acute presentations; conveniently organised into a systems based approach. The information covered is comprehensive, yet still conveyed in a concise manner. The layout is also consistent across the different presentations, each giving: About, Aetiology, Clinical presentation, Investigations, and Management”.

Graphic Anaesthesia is a compendium of the diagrams, graphs, equations and tables needed in anaesthetic practice. Each page covers a separate topic to aid rapid review and assimilation. The relevant illustration, equation or table is presented alongside a short description of the fundamental principles of the topic and with clinical applications where appropriate.Now fully updated, this second edition contains 35 new topics, including significant additions to the drugs and equipment sections, and new sections on clinical prediction and anatomy related to regional anaesthesia.The book includes main sections on:physiologypharmacodynamics and kineticsphysicsequipmentanatomydrugsclinical measurementclinical predictionstatistics.By combining all the illustrations, equations and tables with concise, clinically relevant explanations, Graphic Anaesthesia is therefore:the ideal revision book for all anaesthetists in traininga valuable aide-memoire for senior anaesthetists to use when teaching and examining trainees.From reviews of the previous edition:"Graphic Anaesthesia is a well-written, easy-to-read book, ideal for trainees studying for primary FRCA examinations... It will be an ideal companion for preparing for exams." Ulster Medical Journal, May 2016"Graphic Anaesthesia is an excellent revision tool that allows trainees approaching exams to prepare in an efficient and simple format. It is a refreshing and unique resource that should be included on any essential revision reading list." European Journal of Anaesthesiology 2016; 33: 610."The diagrams are very clear, the explanations accurate and concise and to pack 245 items into a small reference book is no mean feat…. Each diagram is drawn in just four colours to enable them to be reproduced easily from memory. This intuitive approach was an eye-opener to me and a valuable lesson in simplicity without losing any essential detail. This is something from which many educators could learn and indeed transfer that skill…This is a quality book that could be a useful investment across the spectrum of practitioners involved in anaesthesia and the teaching of anaesthesia." Journal of Perioperative Practice March 2017, volume 27, issue 3

This book will help you to understand and appraise clinical research articles and guidelines and assess how they should influence your practice.Assuming no prior knowledge, Clinical Evidence Made Easy starts by explaining the theory of evidence-based practice, including:understanding the hierarchy of evidencehow to recognize biasassessing research papersmaking sense of qualitative researchmaking use of clinical guidelineswhat to do with evidence from pharmaceutical companieshow to apply the evidence in real life.The book concludes with a section covering clinical evidence at work (completely updated for this new edition) which:provides you with simple appraisal tools that you can use to evaluate research papers and clinical guidanceuses extracts from original journal articles to show how you can put the appraisal tools and theory into practice.This new edition has been thoroughly revised and updated, and now features ‘Test your understanding’ questions for each chapter, along with answers at the end of the book.

At a time when primary care has never been busier, the ability to assess effectively by telephone is vitally important. By understanding the problems of this demanding and risk-prone area, clinicians are better able to balance patient needs with workload demands and access to face-to-face appointments.This book provides GPs, practice nurses and out-of-hours workers with a practical guide to what is required when undertaking triage or consultations on the telephone. Using real-world examples throughout, the book offers:A step-by-step guide to the basic principles of telephone assessmentA summary of the potential pitfalls and how to avoid themGuidance on how to quality-assure each call before concluding safelyProtocols to use for every callTelephone Assessment in Primary Care is based around the author’s personal experience working in clinical telephone services. In addition, her work running training courses on telephone triage and consultation helps her to highlight common problems and provide practical solutions.

Totally revised and updated edition now mapped to the UKMLA (Medical Licensing Assessment) curriculum“I like the unique style … It is simple, engaging and easy to read, whatever your learning preferences (I particularly like the colour coding!). It also covers topics comprehensively, making it not only a great aide-memoire but also a very useful everyday book on the ward.” From the Foreword by Professor Farah Bhatti OBE, Consultant Cardiothoracic SurgeonAll the core knowledge you need at medical school in one place!General Medicine and Surgery: Medical Student Revision Guide contains the core information you need on: Cardiology; Endocrinology; Gastroenterology; Hepato-pancreato-biliary; Haematology; Immunology & Allergy; Neurology; Renal; Respiratory; General surgical principles; The acute abdomen; Gastrointestinal surgery; The breast; Vascular surgery; Urology; Critical illness; Emergency presentations; Rheumatology; Trauma & orthopaedics.Throughout medical school, and the years thereafter, a huge volume of knowledge must be acquired and retained, to achieve the standards expected of a safe and successful doctor. This is a mammoth task.General Medicine and Surgery: Medical Student Revision Guide is designed to make accessing and remembering core knowledge as easy as possible: each topic is presented in a colourful, revision-ready note format, with extensive use of diagrams, tables and flowchartskey points are highlighted and core concepts summarised, making the information easier to digest, assimilate and memorisea consistent structure means you always have access to clinical presentation, investigations and management, risk factors and complications.Every chapter has been peer-reviewed by a specialist in the field, to ensure it is accurate and reflects the most up-to-date guidelines.In addition, these specialists have also used their own personal experience of studying for medical exams to ensure that the books focus on the most important conditions, concepts and vocabulary needed to pass finals.General Medicine and Surgery: Medical Student Revision Guide is the perfect companion for your medicine degree, exam revision, medical finals and your early career as a foundation doctor.

Covers the most common conditions seen in an out-of-hours primary care or urgent medical care setting.Urgent and Out-of-Hours Primary Care, updated edition, provides practical guidance on the diagnosis and management of the acute medical conditions seen most commonly in an out-of-hours setting.This edition has been updated and now includes a chapter on managing abnormal blood test results.Key Features:Covers over 200 acute medical conditions commonly encountered when working in an urgent and primary care settingColour photographs provide the reader with further important information on assessing patients presenting with acute medical conditionsKey ‘red flag’ features are highlighted in boxesThe latest guidance and prescribing information is providedUses a consistent approach: each condition features discussions of presentation, assessment and managementOffers practical guidance on how to use telephone triage, video consultations and home visits effectivelyAssumes access to basic diagnostic aids onlyProvides differential diagnoses by symptomHelps manage abnormal lab resultsIndicates when to refer to hospital and when to order an emergency ambulanceThis book is aimed at GPs, GP trainees, doctors, medical students, nurses, paramedics, pharmacists and other healthcare professionals involved in providing urgent and out-of-hours primary care to patients.

It’s 16.10 on a Friday afternoon on a busy on-call day: you have just managed to find the time to review and action your lab results:37 results in the inbox… here we go…Is this serious? Does the patient need admission to hospital today?It’s just out of the reference range – shall I consider that normal and tickas ‘no action required’?Should I just repeat the test, but what testing interval is appropriate?Are there other tests to request that may help in the diagnosis andmanagement?To answer these questions, and many more, the book is split into two main sections:Clinical chapters covering clinical biochemistry, haematology, immunology and rheumatology, and microbiology, which review:Managing individual abnormal test resultsBackground informationCausesHistory and examinationInvestigations: initial and further tests to considerReferralGP management tipsThe role of specific testsIndications for useInterpretation tipsInvestigations to consider for specific clinical scenarios and common signs and symptoms presenting to primary care:Initial tests to performFurther tests to consider Lab Results Made Easy is essential reading for everyone looking to safely manage abnormal results in primary care – it will help with decision-making, especially at 16.10 (and later) on those Friday afternoons…

The second edition of Rheumatology: A clinical handbook has been fully revised and updated. It remains an essential resource for medical students who need an introduction, understanding and overview of the subject.Most competing texts either burden medical students with information they do not require, or cover rheumatology alongside orthopaedics and as a result compromise fundamentals of rheumatology.This book is different:It provides all the information students need during their rheumatology placementFurther information resources are signposted for those who want to take their studies furtherA definition and brief pathophysiology for each condition is provided, which is linked to the respective clinical features.The book covers the core elements of diagnosis and treatment based on the latest national guidelines to swiftly bring students and junior doctors in training up-to-date.Self-assessment questions and an OSCE chapter provide a way of checking that users have understood and grasped the core material, as well as enabling students to be well equipped for their written and OSCE examinations.Written by a medical student, a GP Principal and an emeritus consultant rheumatologist, the book combines a reader-friendly writing style with coverage of the material through clinical experience of a professional in the field.Printed in full colour throughout, with an attractive design, a clear and concise writing style as well as a range of pedagogical features including an array of mnemonics, pictures and diagrams, Rheumatology: A clinical handbook is exactly the sort of book medical students and newly qualified doctors would benefit from.

Essential ECG is a hands-on, accessible guide to recording, interpreting, and reporting ECGs with confidence.The book begins with a clear explanation of the heart’s normal conduction system, then walks readers through lead placement and anatomical perspectives. It breaks down every component of a normal ECG before introducing a straightforward, practical algorithm for interpreting ECGs in any clinical scenario.Covers all major ECG abnormalities – from prolonged intervals and electrolyte imbalances to pericardial disease and pulmonary embolism.Seamlessly blends ECG findings with relevant clinical context for better real-world application.Features an extensive library of real-life ECGs, all clearly annotated and consistently presented to highlight key abnormalities.Ends with a ‘test yourself’ section: 50 ECGs that are common, critical or potentially life-threatening, each paired with a concise interpretation and diagnostic insight.Essential ECG is the go-to resource for medical students, residents, and allied health professionals looking to sharpen their ECG interpretation skills and apply them effectively in everyday clinical practice.

Whole genome amplification generates microgram quantities of genomic DNA starting from a sample of as little as a few femtograms and so is a vital technique when sample material is limited, as well as for high-throughput assays. Whole Genome Amplification: Methods Express is a comprehensive up-to-date laboratory manual for this key technique. It provides detailed step-by-step protocols as well as hints and tips for success and troubleshooting, taking readers through all aspects of whole genome amplification. This book is an essential practical guide for any researcher currently using PCR for genomic amplification or who wishes to do so in future.

DNA Microarrays: Methods Express covers the very latest in DNA microarray technology, with a clear focus on how these techniques can be used in the lab to gain the very best results. The authors are from some of the leading laboratories in the field and write with real authority on the latest methodology. Every chapter provides detailed step-by-step protocols with valuable hints and tips for success, as well as giving typical experimental results and selected literature citations. This book is a 'must have' manual for researchers in all fields of biology, medicine and agriculture.

DNA Microarrays: Methods Express covers the very latest in DNA microarray technology, with a clear focus on how these techniques can be used in the lab to gain the very best results. The authors are from some of the leading laboratories in the field and write with real authority on the latest methodology. Every chapter provides detailed step-by-step protocols with valuable hints and tips for success, as well as giving typical experimental results and selected literature citations.This book is a 'must have' manual for researchers in all fields of biology, medicine and agriculture.

Bioinformatics: Methods Express is unique. It is a book on bioinformatics that makes sense to non-bioinformaticians.Bioinformatics: Methods Express helps you answer common questions such as: *what else is similar to my gene?*does this protein have any transmembrane regions?*how do I visualize an alignment between these DNAs?*where can I find specific transcription factor sequences?The book provides the clear advice and explicit protocols that non-bioinformaticians need in order to understand what to do - and how to avoid common pitfalls. Each chapter guides you through the major databases and tools with worked examples - all accompanied by sample data files available online.Topics covered include:*data access*sequence searches and alignments*identification and annotation of features*the transcriptome*protein structure and function*comparisons and phylogenyBioinformatics: Methods Express is a comprehensive manual for all wet-bench scientists who need to use bioinformatics - from postgraduate student to principal investigator.www.scionpublishing.com/bioinformatics contains comprehensive datasets which allow the reader to practise the techniques described in the book.

Getting into GP Training is a practical guide for anyone planning to become a GP and so looking to enrol in a GP Specialty Training Programme.Uniquely, this book covers all stages of the application process, from the initial longlisting and application to a General Practice Deanery (Stage 1), through the computer-based tests at Stage 2, the selection tests at Stage 3, and allocation to a Deanery (Stage 4).Written by an author who has recently been through the whole application process himself, this book includes full practice papers for the Stage 2 and 3 exams. It is packed full of hints and tips for all stages of the application process to help the reader succeed in the application process and enter the training programme of their choice.

This book covers the key techniques that can be employed in any lab with access to cell imaging equipment, even if they do not currently specialize in imaging. It focuses on live cell imaging and light microscopy applications, but is equally relevant to the imaging of fixed specimens.