Fundamentals of Genetic Epidemiology

"Gives the first serious exposition [of genetic epidemiology] as an aspect of epidemiology. Geneticists will find it an appealing introduction to epidemiologic terms and concepts, while epidemiologists should find common ground even in developments traditionally far outside their discipline. . . . this is a book that should be in the library of every genetic epidemiologist and should be considered as a text." --Journal of Genetic Epidemiology"Excellent. The explanation of the logic of quite sophisticated statistical techniques of data analysis is excellent. This readable book provides a reliable summary of all but the most recent work in the overlapping areas of human genetics and human epidemiology. It should be purchased and used by all those undertaking population or family studies of human disease. It will also be a useful reference book for teachers preparing course on the subject." --R.N.Currow, American Journal of Epidemiology"Does a very good job of introducing the field of genetic epidemiology....One interesting feature...is the way the authors weave the separate fields of genetics and epidemiology together to highlight the contribution of each to genetic epidemiology....Covers a variety of important topics well, at a level readily accessible to geneticists, epidemiologists, and statisticians. One very useful feature is the extensive reference list to work in geneticepidemiology....A very good introduction, and overview of, an increasingly important field." --Statistical Methods in Medical Research

• 1. Scope and strategies of genetic epidemiology ; 2. Fundamental genetic concepts and approaches ; 3. Fundamental epidemiologic concpets and approaches ; 4. Study of genetic traits ; 5. Study of the genetic factors in disease ; 6. Epidemiologic approaches to familial aggregation ; 7. Genetic approaches to familial aggregation: Heritability ; 8. Genetic approaches to familial aggregation: Segregation Analysis ; 9. Genetic approaches to familial aggregation: Linkage Analysis ; 10. Applications of genetic epidemiology in medicine and public health