Massive data streams, large quantities of data that arrive continuously, are becoming increasingly commonplace in many areas of science and technology. Consequently development of analytical methods for such streams is of growing importance. To address this issue, the National Security Agency asked the NRC to hold a workshop to explore methods for analysis of streams of data so as to stimulate progress in the field. This report presents the results of that workshop. It provides presentations that focused on five different research areas where massive data streams are present: atmospheric and meteorological data; high-energy physics; integrated data systems; network traffic; and mining commercial data streams. The goals of the report are to improve communication among researchers in the field and to increase relevant statistical science activity.