Drug Delivery and Biomedical Applications of Porous Silicon-Based Nanocarriers

Rajendra Awasthi is Professor of Pharmaceutics at Department of Pharmaceutical Sciences, School of Health Sciences & Technology, University of Petroleum and Energy Studies, UPES, Dehradun, India. Santosh Kumar Singh, PhD, is a Senior Scientist at the Centre of Experimental Medicine and Surgery, Institute of Medical Sciences, Banaras Hindu University, Varanasi, India. He has more than 25 years of research experience and has led projects supported by the Department of Science and Technology, Department of Biotechnology, and Science and Engineering Research Board. His academic activities include supervising doctoral and postdoctoral researchers and medical trainees across MD, MS, DM, and MCh programmes. He previously conducted postdoctoral research at Banaras Hindu University and served as a Visiting Scientist at the Institute of Physical Biology, University of South Bohemia, Czech Republic. He also contributes to scholarly publishing through service on the editorial boards of scientific journals. Anurag Kumar Singh, PhD, is a Research Associate in the Department of Pharmaceutical Engineering and Technology at the Indian Institute of Technology (Banaras Hindu University), Varanasi, India. His research focuses on developing nanoparticulate systems for chronic pain, neurodegenerative disorders, brain-targeted drug delivery, diagnostics, and therapy. His work includes dendrimers, nanoporous silica and silicon materials, and polymeric nanoparticles for controlled drug delivery, with broader interests in nanomedicines for biomedical and healthcare applications and in integrating engineering, pharmaceutical, and medical research. He previously held postdoctoral research positions in cancer biology at Alabama State University, USA, and in nanotechnology and advanced materials at Bar-Ilan University, Israel.

• 1. Historical advancements in targeted nanoscale drug delivery systems2. Synthesis of Porous Silicon-based Nanoparticles3. Characterization techniques for mesoporous silicon nanoparticles4. Mesoporous silicon for solubility enhancement of drugs5. Porous silicon-based nanocarriers for tumor targeting6. Porous silicon and related composites for topical drug delivery7. Porous silicon nanocarriers for the management of neurodegenerative disorders8. Functionalized silica nanocarriers for brain targeted delivery9. Porous silicon-based materials in nanoneedle and microneedle-based drug delivery systems10. Porous silicon-based drug delivery carriers in cancer management11. Stimuli-responsive silica nanoparticles: Smart systems for controlled drug delivery12. Mesoporous silica-based nanocarriers in pulmonary drug delivery13. Porous silicon nanoparticles for improved cellular uptake and targeted drug delivery14. Recent advances in porous silicon-based technology for biomedical applications15. Immunotherapeutic applications of porous silicon nanoparticles16. Bioengineered porous silicon nanoparticles in vaccine development17. Bioavailability enhancement of poorly soluble drugs with mesoporous silicon18. Silica nanoparticles in clinical trials19. Mesoporous silica nanoparticles for therapeutic uses: from bench to clinics20. Future perspectives of mesoporous silica-based nanocarriers in drug delivery