Anurag Kumar Singh – författare

Drug Delivery and Biomedical Applications of Porous Silicon-Based Nanocarriers delivers an up-to-date and complete overview of the range of biomedical applications for porous silicon nanomaterials, with a special emphasis on drug delivery. This book introduces the fundamentals and beneficial properties of porous silicon, including thermal properties and stabilization, photochemical and nonthermal chemical modification, protein modification, and biocompatibility. The book then builds on the systematic detailing of each biomedical application using porous silicon, such as vaccine development, drug delivery, and tissue engineering. It also contains new insights on in-vivo assessment of porous silicon, photodynamic and photothermal therapy, micro- and nanoneedles, cancer immunotherapy, and more. Drug Delivery and Biomedical Applications of Porous Silicon-Based Nanocarriers is of interest to researchers in the fields of materials science, nanotechnology, pharmaceutical science, biomedical engineering, and cancer research.Details synthesis approaches and methodologies for porous silicon-based nanocarriers, enabling structural understanding and therapeutic applicationsHighlights the role of silica nanoparticles in targeted drug delivery, emphasizing their impact on cancer therapy, immunotherapy, neurodegenerative disorders, and other biomedical applicationsExplores clinical aspects and trials of silica nanoparticles for treatment options

Nanogels: Fundamentals to Pharmaceutical and Biomedical Applications provides a comprehensive overview of nanogels, focusing on design principles, crosslinking methods, and therapeutic agent delivery. It covers nanogels' thermal properties, stabilization, chemical modifications, and biocompatibility. The book details biomedical applications, including bioimaging, sensing, drug delivery, and tissue engineering. It also explores in-vivo assessments, responsive therapies, and safety considerations, including toxicity, clearance mechanisms, and immunological responses, offering new insights into nanogel technology.Nanogels: Fundamentals to Pharmaceutical and Biomedical Applications offers an exciting look into this emerging area and is of particular interest to healthcare professionals and researchers working on nanocarrier-based drug delivery, focusing on porous nanogel nanocarriers.Describes the current and future prospective of biomedical applications of nanogels, emphasizing their role in drug delivery, targeted therapy, imaging, diagnostics, and tissue engineering. Explores their potential to address critical healthcare challenges, serving as a valuable resource for researchers and practitionersDelivers a fully updated and complete overview of the range of biomedical applications for nanogelsExplores cutting-edge nanogel research and emerging trends, offering future insights while addressing toxicity assessment, clearance mechanisms, and long-term effects to ensure safe biomedical applications of these innovative materials

Nano-Bio-Medicine for Gastrointestinal Diseases explores the transformative potential of biomedicine in gastroenterology, from innovative drug delivery systems to nanoscale imaging techniques. The book's content offers a detailed analysis of emerging technologies that are revolutionizing the diagnosis, treatment, and management of gastrointestinal disorders. By addressing conditions like inflammatory bowel disease and gastrointestinal cancers, readers gain a holistic understanding of how biomedicine is reshaping the entire landscape of gastroenterology. With a focus on personalized medicine approaches and future perspectives, this book inspires collaboration and awareness among researchers, medical practitioners, and patients, ultimately leading to improved outcomes and quality of life. Sections cover a wide range of topics that are essential for understanding the intersection of biomedicine and gastroenterology. Beginning with an introduction to NanoBioMedicine and its application in gastrointestinal diseases, readers are guided through nanoscale drug delivery systems, nanoimaging techniques, and nanotheranostics in cancer treatment. Specific chapters address the role of nanotechnology in managing conditions like inflammatory bowel disease and celiac disease, while also exploring the integration of artificial intelligence and big data analytics.Offers a thorough examination of various gastrointestinal conditions such as inflammatory bowel disease, celiac disease, gastrointestinal cancers, and pancreatitisShowcases how biomedicine is reshaping the landscape of gastroenterologyExplores cutting-edge advancements in gastroenterology, including precision medicine, the microbiome-gut-brain axis, endoscopic innovations, and the integration of artificial intelligence and big data analyticsEmphasizes personalized medicine approaches, showcasing the importance of tailoring treatments to each patient's unique characteristics and disease profiles

This book discusses basics of brain diseases and the role of nanobiotechnology in existing treatment options for neurodegenerative disorders. It begins with an overview of brain diseases and the need for novel drug-delivery approaches. It highlights the current route for the intranasal advanced drug-delivery systems for brain diseases. It also discusses innovative categories of drug-delivery systems, including mesoporous silica nanoparticles, polymeric nanocarriers, and lipid-based nanocarriers through multi-responsive DDSs and their implications in brain disorders.Features:Includes an overview of brain diseases and highlights the need for novel drug-delivery approachesFocuses on theoretical aspects of advanced drug-delivery systems for brain diseases including challenges and progress in nose-to-brain deliveryProvides an overview of technological approaches and their implications for neurodegenerative disorders, central nervous system (CNS), and brain drug delivery in brain cancerDiscusses key advances in the development of polymer nanoparticles for drug delivery to the CNSReviews the role of herbal medicines and naturally derived polymeric nanoparticle for the treatment of neurodegenerative disordersThis book is aimed at graduate students and researchers in biomedical engineering, biotechnology, drug delivery, and neurology.

This book discusses basics of brain diseases and the role of nanobiotechnology in existing treatment options for neurodegenerative disorders. It begins with an overview of brain diseases and the need for novel drug-delivery approaches. It highlights the current route for the intranasal advanced drug-delivery systems for brain diseases. It also discusses innovative categories of drug-delivery systems, including mesoporous silica nanoparticles, polymeric nanocarriers, and lipid-based nanocarriers through multi-responsive DDSs and their implications in brain disorders.Features:Includes an overview of brain diseases and highlights the need for novel drug-delivery approachesFocuses on theoretical aspects of advanced drug-delivery systems for brain diseases including challenges and progress in nose-to-brain deliveryProvides an overview of technological approaches and their implications for neurodegenerative disorders, central nervous system (CNS), and brain drug delivery in brain cancerDiscusses key advances in the development of polymer nanoparticles for drug delivery to the CNSReviews the role of herbal medicines and naturally derived polymeric nanoparticle for the treatment of neurodegenerative disordersThis book is aimed at graduate students and researchers in biomedical engineering, biotechnology, drug delivery, and neurology.

This book spotlights the potential of nanozymes in combating antimicrobial resistance (AMR), a growing global health crisis with high mortality and morbidity. Despite progress in understanding AMR, current therapies often fall short. Nanozymes, a novel class of enzyme-mimicking nanomaterials, offer diverse applications to address AMR and related infections. By enhancing targeted drug delivery, nanozyme-based treatments improve efficacy while reducing adverse effects, highlighting their potential to overcome the limitations of existing therapies.AMR, driven by the overuse and misuse of antibiotics, is an escalating global challenge that results in resistant bacterial strains and significant health burdens. Current treatments lack optimal efficacy, emphasizing the need for innovative approaches. Nanozymes, with their enzyme-like catalytic activities at the nanoscale, present a promising solution to the complexities of AMR and associated infections.Nanozymes offer a significant advantage in antimicrobial resistance (AMR) management by enhancing the efficacy of treatments. These formulations can navigate biological barriers with precision, improving drug bioavailability and minimizing off-target effects. Additionally, nanozymes facilitate early disease detection through advanced nano-imaging techniques, allowing the identification of infections and resistant bacteria at early stages-crucial for timely interventions. They can also carry anti-inflammatory agents, providing targeted relief and reducing systemic side effects.In summary, nanozymes are a transformative tool in AMR management, addressing the limitations of current therapies. By improving drug delivery, enabling early detection, and offering precision therapeutics, nanozymes enhance treatment effectiveness while minimizing adverse effects. Their versatility opens avenues for personalized treatment regimens, paving the way for innovative, tailored healthcare solutions that can better meet the challenges of AMR, ultimately improving patient outcomes and public health.This book targets scientists and researchers in AMR, drug delivery, and nanomaterials, covering AMR fundamentals to advanced nanozyme applications. It offers detailed, up-to-date insights, serving as a vital resource for students, clinicians, academics, and industry professionals across various scientific disciplines.