Peptide and Protein Engineering

From Concepts to Biotechnological Applications

AvOlga Iranzo,Ana Cecília Roque

Inbunden, Engelska, 2020

Del i serien Springer Protocols Handbooks

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Beskrivning

It opens with a section on chemical tools applied to the production or engineering of peptides and proteins, and concludes with a collection of chapters on biological approaches used to engineer structure and function in peptides and proteins.

Produktinformation

Utgivningsdatum:2020-07-09
Mått:178 x 254 x 22 mm
Vikt:772 g
Format:Inbunden
Språk:Engelska
Serie:Springer Protocols Handbooks
Antal sidor:289
Förlag:Springer-Verlag New York Inc.
ISBN:9781071607190

Utforska kategorier

Biokemi inom Naturvetenskap och teknik
Biokemisk teknik inom Naturvetenskap och teknik
Kemi inom Naturvetenskap och teknik

Innehållsförteckning

SEA Ligation is Accelerated at Midly Acidic pH: Application to the Formation of Difficult Peptide Junctions.- The Problem of Aspartimide Formation during Protein Chemical Synthesis Using SEA-Mediated Ligation.- Using the Interactive Tool of the Protein Chemical Synthesis Database.- Only a “Click” Away: Development of Arginine-Rich Peptide-Based Materials Using Click Chemistry.- Fluoroglycoproteins by Copper-Free Strain-Promoted Azide–Alkyne Cycloaddition.- Hybrid Silylated Peptides for the Design of Bio-Functionalized Materials.- Synthesis of Peptide-Oligoethylene Glycol (OEG) Conjugates for Multivalent Modification of Nanomaterials.- Phage Display Methodologies.- Whole-Bacterium Ribosome Display Selection for Isolation of Anti-Bacterial Affitins.- CIS Display: DNA-Based Technology as a Platform for Discovery of Therapeutic Biologics.- Building Scarless Gene Libraries in the Chromosome of Bacteria.- Streptavidin (Sav)-Based Artificial Metalloenzymes: Cofactor Design Considerations and Large Scale Expression of Host Protein Variants.- Integrated Bacterial Production of Large Combinatorial Libraries of Cyclic Oligopeptides and Functional Screening for the Identification of Chemical Rescuers of Pathogenic Protein Misfolding and Aggregation.- Site-Specific Incorporation of Non-Canonical Amino Acids by Amber Stop Codon Suppression in Escherichia coli.