This edited volume critically examines the coloniality of humanity and how it affects colonized and racialized people in both the Global South and Global North. The contributors reveal how ongoing geopolitical power imbalances are rooted in colonial histories and colonial structures which perpetuate global inequalities. The volume explores how these entrenched colonial systems intersect with gender, class, disability, and other social factors, often overlooked in mainstream discussions of global inequality. By synthesizing empirical research and theoretical perspectives on race and colonialism across various historical and geographical contexts, it emphasizes the importance of combining postcolonial research with decolonial praxis. Through the perspectives of scholars and activists from the Global South, the book aims to decolonize knowledge production and challenge the continuing dominance of coloniality.