Transcriptomics in Health and Disease

Häftad, Engelska, 2016

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Beskrivning

Transcriptomics in Heath and Disease provides a comprehensive overview of the science of transcriptomics initially in health, focusing on the concept of the transcriptome and the main methods to evaluate it.

Produktinformation

Utgivningsdatum:2016-10-22
Mått:155 x 235 x 20 mm
Vikt:552 g
Format:Häftad
Språk:Engelska
Antal sidor:344
Förlag:Springer International Publishing AG
ISBN:9783319350141

Utforska kategorier

Biokemi inom Naturvetenskap och teknik
Biovetenskap inom Naturvetenskap och teknik
Medicinsk genetik inom Medicin

Innehållsförteckning

Part 1: Basic Principles of the Transcriptome and its Analysis.- What is the Transcriptome and how it is Evaluated?.- Transcriptome Analysis Throughout RNA-seq.- Identification of Biomarkers and Expression Signatures.- Methods for Gene Co-expression Network Visualization and Analysis.- Posttranscriptional Control During Stem Cells Differentiation.- Transcriptome Analysis During Normal Human Mesenchymal Stem Cell Differentiation.- Part II: Transcriptome in Disease.- Thymus Gene Co-expression Networks: A comparative study in children with and without down syndrome.- Transcriptome Profiling in Autoimmune Diseases.- Expression of DNA Repair and Response to Oxidative Stress Genes in Diabetes Mellitus.- MicroRNAs in Cancer.- Transcriptome Profiling in Chronic Inflammatory Diseases of the Musculoskeletal System.- Transcriptome Profiling in Experimental Inflammatory Arthritis.- Transcriptome in Human Mycoses.- Transcriptomics of the Host-pathogen Interaction in Paracoccidioidomycosis.- Dissecting Tuberculosis through Transcriptomic Studies.- Understanding chagas Disease by Genome and Transcriptome Exploration.- Expression Tests in Actual Clinical Practice: How medically useful is the transcriptome?.- Conclusions.- Index.