Their efficient production requires comprehensive knowledge of biological as well as biochemical mammalian cell culture fundamentals (e.g., cell characteristics and metabolism, cell line establishment, culture medium optimization) and related engineering principles (e.g., bioreactor design, process scale-up and optimization).
Mammalian Cells.- Mammalian Cell Culture Technology: An Emerging Field.- Characteristics of Mammalian Cells and Requirements for Cultivation.- Bioreactors for Mammalian Cells: General Overview.- Special Engineering Aspects.- Bioreactor Design and Scale-Up.- Special Applications.- Insect Cell-Based Recombinant Protein Production.- Bioreactors for Bioartificial Organs.- Plant Cell-Based Bioprocessing.