Carolyn Shore – författare
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16 produkter
Innovation in Drug Research and Development for Prevalent Chronic Diseases
Proceedings of a Workshop
Av and Translation Forum on Drug Discovery, Development, Board on Health Sciences Policy m. fl.
E-bok, 2021
446 kr
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Investment and innovation in drug research and development (R&D) for highly prevalent chronic diseases has stalled in recent decades, despite half of all Americans living with at least one chronic disease. As a result, prevalent chronic diseases are producing immense health care costs as well as …
Envisioning a Transformed Clinical Trials Enterprise for 2030
Proceedings of a Workshop
Av and Translation Forum on Drug Discovery, Development, Board on Health Sciences Policy m. fl.
E-bok, 2022
446 kr
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The evolution of health care is expanding the possibilities for integration of clinical research into the continuum of clinical care; new approaches are enabling the collection of data in real-world settings; and new modalities, such as digital health technologies and artificial intelligence …
Building Resilience into the Nation's Medical Product Supply Chains
Av Committee on Security of America's Medical Product Supply Chain, Board on Health Sciences Policy m. fl.
E-bok, 2022
660 kr
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Over the past several decades, supply chain disruptions have repeatedly plagued the U.S. health care system, costing health care systems millions of dollars per year, threatening the clinical research enterprise, and most importantly, imperiling the health and lives of patients. The Committee on …
Examining the Impact of Real-World Evidence on Medical Product Development
Proceedings of a Workshop Series
Av and Translation Forum on Drug Discovery, Development, Board on Health Sciences Policy m. fl.
E-bok, 2019
960 kr
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Randomized controlled trials (RCTs) have traditionally served as the gold standard for generating evidence about medical interventions. However, RCTs have inherent limitations and may not reflect the use of medical products in the real world. Additionally, RCTs are expensive, time consuming, and …
Virtual Clinical Trials
Challenges and Opportunities: Proceedings of a Workshop
Av and Translation Forum on Drug Discovery, Development, Board on Health Sciences Policy m. fl.
E-bok, 2019
803 kr
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Successful drug development relies on accurate and efficient clinical trials to deliver the best and most effective pharmaceuticals and clinical care to patients. However, the current model for clinical trials is outdated, inefficient and costly. Clinical trials are limited by small sample sizes …
Enhancing Scientific Reproducibility in Biomedical Research Through Transparent Reporting
Proceedings of a Workshop
Av and Translation Forum on Drug Discovery, Development, Forum on Neuroscience and Nervous System Disorders m. fl.
E-bok, 2020
814 kr
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Sharing knowledge is what drives scientific progress - each new advance or innovation in biomedical research builds on previous observations. However, for experimental findings to be broadly accepted as credible by the scientific community, they must be verified by other researchers. An essential …
Reflections on Sharing Clinical Trial Data
Challenges and a Way Forward: Proceedings of a Workshop
Av and Translation Forum on Drug Discovery, Development, Forum on Neuroscience and Nervous System Disorders m. fl.
E-bok, 2020
981 kr
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On November 18 and 19, 2019, the National Academies of Sciences, Engineering, and Medicine hosted a public workshop in Washington, DC, titled Sharing Clinical Trial Data: Challenges and a Way Forward. The workshop followed the release of the 2015 Institute of Medicine (IOM) consensus study report …
Role of Digital Health Technologies in Drug Development
Proceedings of a Workshop
Av and Translation Forum on Drug Discovery, Development, Roundtable on Genomics and Precision Health m. fl.
E-bok, 2020
952 kr
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On March 24, 2020, a 1-day public workshop titled The Role of Digital Health Technologies in Drug Development was convened by the National Academies of Sciences, Engineering, and Medicine. This workshop builds on prior efforts to explore how virtual clinical trials facilitated by digital health …
Drug Research and Development for Adults Across the Older Age Span
Proceedings of a Workshop
Av and Independence Forum on Aging, Disability, and Translation Forum on Drug Discovery, Development m. fl.
E-bok, 2021
589 kr
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There is a void in evidence-based information for making informed decisions on how to optimize care for older adults, particularly those 80 years and over. Because older adults are vastly underrepresented in clinical trials, there is a dearth of information about the appropriate use of drugs in …
Inclusion of Pregnant and Lactating Persons in Clinical Trials
Proceedings of a Workshop
Av and Translation Forum on Drug Discovery, Development, Board on Health Sciences Policy m. fl.
E-bok, 2023
339 kr
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Approximately 4 million pregnant people in the United States give birth annually, and 70 percent of these individuals take at least one prescription medication during their pregnancy. Yet, due to a number of historical, ethical, legal, scientific, and societal issues, pregnant and lactating persons …
Accelerating the Development and Uptake of Rapid Diagnostics to Address Antibiotic Resistance
Proceedings of a Workshop
Av and Translation Forum on Drug Discovery, Development, Forum on Medical and Public Health Preparedness for Disasters and Emergencies m. fl.
E-bok, 2023
339 kr
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The use and misuse of antibiotics contributes to the rise in drug-resistant bacteria - a serious and worsening threat to human health. The development and use of rapid point-of-care diagnostics in the healthcare setting plays an important role in avoiding unnecessary use of antimicrobials by …
Defining and Evaluating In-Home Drug Disposal Systems For Opioid Analgesics
Proceedings of a Workshop
Av and Translation Forum on Drug Discovery, Development, Board on Health Sciences Policy m. fl.
E-bok, 2024
314 kr
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The proper disposal of unused or expired prescription drugs, particularly controlled substances such as opioids, may help to prevent serious risk of nonmedical use or overdose. In June 2023, the National Academies Forum on Drug Discovery, Development, and Translation hosted a hybrid public workshop …
Preparing the Future Workforce in Drug Research and Development
Proceedings of a Workshop
Av and Translation Forum on Drug Discovery, Development, and Medicine Roundtable on Black Men and Black Women in Science, Engineering m. fl.
E-bok, 2024
332 kr
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Despite advances over the past several decades, the clinical trials enterprise has struggled to meet the needs of an increasingly diverse U.S. population. To help address this issue, a 2023 National Academies workshop sought to identify the expertise and disciplines needed to achieve the …
Adult Attention-Deficit/Hyperactivity Disorder
Diagnosis, Treatment, and Implications for Drug Development: Proceedings of a Workshop
Av and Translation Forum on Drug Discovery, Development, Forum on Neuroscience and Nervous System Disorders m. fl.
E-bok, 2024
357 kr
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Attention deficit/hyperactivity disorder (ADHD) diagnosis and treatment among adults has increased over the past decade in the U.S. and globally. Evidence suggests adults with ADHD may be more likely to develop a substance use disorder, and there are concerns that nonmedical use of prescription …
Toward a Framework to Improve Diversity and Inclusion in Clinical Trials
Proceedings of a Workshop
Av and Translation Forum on Drug Discovery, Development, National Cancer Policy Forum m. fl.
E-bok, 2025
268 kr
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Despite decades of ongoing efforts to improve racial and ethnic diversity in clinical trials, many gaps remain in achieving demographic representation in clinical studies. In May 2024, the National Academies Forum on Drug Discovery, Development, and Translation, in collaboration with the National …
Building Resilience into the Nation's Medical Product Supply Chains
Av and Medicine National Academies of Sciences, Engineering, Health and Medicine Division m. fl.
Häftad, 2022
435 kr
Tillfälligt slut
Over the past several decades, supply chain disruptions have repeatedly plagued the U.S. health care system, costing health care systems millions of dollars per year, threatening the clinical research enterprise, and most importantly, imperiling the health and lives of patients. The Committee on …