Murugan Ramalingam – författare

Nanofiber Composite Materials for Biomedical Applications presents new developments and recent advances in nanofiber-reinforced composite materials and their use in biomedical applications, including biomaterial developments, drug delivery, tissue engineering, and regenerative medicine.

Unlike more conventional titles on composite materials, this book covers the most innovative new developments in nanofiber-based composites, including polymers, ceramics, and metals, with particular emphasis on their preparation and characterization methodology.

Selected case studies illustrate new developments in clinical and preclinical use, making the information critical for the development of new medical materials and systems for use in human health care, and for the exploration of new design spaces based on these nanofibers. This book is essential reading for those working in biomedical science and engineering, materials science, nanoscience, biomedical nanotechnology, and biotechnology.

Covers innovative new developments in nanofiber composites, including polymers, ceramics, and metals with particular emphasis on their preparation and characterization methodology Deals with biomedical applications, including biomaterials developments, drug delivery, tissue engineering, and regenerative medicine Presents selected case studies on nanofiber composite materials in both clinical and preclinical use

Stem Cell Biology and Tissue Engineering in Dental Sciences bridges the gap left by many tissue engineering and stem cell biology titles to highlight the significance of translational research in this field in the medical sciences. It compiles basic developmental biology with keen focus on cell and matrix biology, stem cells with relevance to tissue engineering biomaterials including nanotechnology and current applications in various disciplines of dental sciences; viz., periodontology, endodontics, oral & craniofacial surgery, dental implantology, orthodontics & dentofacial orthopedics, organ engineering and transplant medicine. In addition, it covers research ethics, laws and industrial pitfalls that are of particular importance for the future production of tissue constructs.

Tissue Engineering is an interdisciplinary field of biomedical research, which combines life, engineering and materials sciences, to progress the maintenance, repair and replacement of diseased and damaged tissues. This ever-emerging area of research applies an understanding of normal tissue physiology to develop novel biomaterial, acellular and cell-based technologies for clinical and non-clinical applications. As evident in numerous medical disciplines, tissue engineering strategies are now being increasingly developed and evaluated as potential routine therapies for oral and craniofacial tissue repair and regeneration.

Diligently covers all the aspects related to stem cell biology and tissue engineering in dental sciences: basic science, research, clinical application and commercialization Provides detailed descriptions of new, modern technologies, fabrication techniques employed in the fields of stem cells, biomaterials and tissue engineering research including details of latest advances in nanotechnology Includes a description of stem cell biology with details focused on oral and craniofacial stem cells and their potential research application throughout medicine Print book is available and black and white, and the ebook is in full color

Biomedical Materials and Diagnostics Devices provides an up-to-date overview of the fascinating and emerging field of biomedical materials and devices, fabrication, performance, and usesThe biomedical materials with the most promising potential combine biocompatibility with the ability to adjust precisely the biological phenomena in a controlled manner. The world market for biomedical and diagnostic devices is expanding rapidly and the pace of academic research resulted in about 50,000 published papers in recent years. It is timely, therefore, to assemble a volume on this important subject.The chapters in the book seek to address progress in successful design strategies for biomedical materials and devices such as the use of collagen, crystalline calcium orthophosphates, amphiphilic polymers, polycaprolactone, biomimetic assembly, bio-nanocomposite matrices, bio-silica, theranostic nanobiomaterials, intelligent drug delivery systems, elastomeric nanobiomaterials, electrospun nano-matrices, metal nanoparticles, and a variety of biosensors.This large and comprehensive volume includes twenty chapters authored by some of the leading researchers in the field, and is divided into four main areas: biomedical materials; diagnostic devices; drug delivery and therapeutics; and tissue engineering and organ regeneration.

A cutting-edge look at the application of micro and nanotechnologies in regenerative medicineThe area at the interface of micro/nanotechnology and stem cells/tissue engineering has seen an explosion of activity in recent years. This book provides a much-needed overview of these exciting developments, covering all aspects of micro and nanotechnologies, from the fundamental principles to the latest research to applications in regenerative medicine.Written and edited by the top researchers in the field, Micro and Nanotechnologies in Engineering Stem Cells and Tissues describes advances in material systems along with current techniques available for cell, tissue, and organ studies. Readers will gain tremendous insight into the state of the art of stem cells and tissue engineering, and learn how to use the technology in their own research or clinical trials. Coverage includes: Technologies for controlling or regulating stem cell and tissue growthVarious engineering approaches for stem cell, vascular tissue, and bone regenerationThe design and processing of biocompatible polymers and other biomaterialsCharacterization of the interactions between cells and biomaterialsUnrivaled among books of this kind, Micro and Nanotechnologies in Engineering Stem Cells and Tissues is the ultimate forward-looking reference for researchers in numerous disciplines, from engineering and materials science to biomedicine, and for anyone wishing to understand the trends in this transformative field.

This book acts as a self-contained resource for understanding the current technological advancement of biomaterials towards tissue engineering applications.  It covers impact of biomaterials at different length scales such as macro/micro/nano/ level and offers extensive discussion on cell-biomaterial interactions with illustrative examples. This resource offer a multi-disciplinary approach for the adaptability of integrated biomaterials in tissue repair and reconstruction.

This cutting edge book provides all the important aspects dealing with the basic science involved in materials in biomedical technology, especially structure and properties, techniques and technological innovations in material processing and characterizations, as well as the applications.The volume consists of 12 chapters written by acknowledged experts of the biomaterials field and covers a wide range of topics and applications including: The different types of nanobiomaterialsHow to generate porous biomaterials for tissue engineeringCalcium phosphate-based biomaterials intended for mineralized tissue regenerative applicationsNanocrystalline form of calcium phosphatesDesign and fabrication of SiO2 nanoparticlesNew kinds of titanium alloy implantsInjectable growth factor system based on bone morphogenetic proteinsImpedance sensing of biological processes in mammalian cellsHydrogels-based implantable glucose sensorsMolecular design of multifunctional polymers for gene transfectionHydrogels and their potential biomedical applicationsHybrid biomaterials with high mechanical and biological properties

Provides cutting-edge advances in biologically inspired, biomimetically-designed materials and systems for developing the next generation of nanobiomaterials and tissue engineeringHumans have been trying to learn biomimetics for centuries by mimicking nature and its behaviors and processes in order to develop novel materials, structures, devices, and technologies. The most substantial benefits of biomimetics will likely be in human medical applications, such as developing bioprosthetics that mimic real limbs and sensor-based biochips that interface with the human brain to assist in hearing and sight.Biomimetics: Advancing Nanobiomaterials and Tissue Engineering seeks to compile all aspects of biomimetics, from fundamental principles to current technological advances, along with future trends in the development of nanoscale biomaterials and tissue engineering.The book details research, useful in inspiring new ideas, that seeks the principles and rules implemented by nature, such as self-assembly, a bottom-up approach in which molecular structures are assembled with little or no external intervention to generate nano, micro, and macro structures.Other subjects covered in the book include: Cartilage tissue engineering as an emerging technologyThe fabrication methods of nanofibrous scaffolds and their potential utility in bone tissue engineering applicationsDental and craniofacial tissue engineering with bioactive polymers and bionanomaterialsStrategies to prevent bacterial adhesion on biomaterialsThe latest achievements in biomimetic ECM scaffolds prepared from cultured cellsGraphene oxide and graphene as promising scaffold materialsStem cells as a source for building tissues or organs in the laboratory

The use of ceramics in biological environments and biomedical applications is of increasing importance, as is the understanding of how biology works with minerals to develop strong materials suitable for the clinic. Bioceramics have been revolutionizing the biomedical field in the form of bone grafts, fillers, implants and metal implant surface coatings for use in humans. Efforts are focusing on understanding and improving the biocompatibility, physico-chemical and mechanical properties of such materials and devices, with the attention directed towards the development and potential use of ceramic/ceramic composites, at micro-, nano- and pico-scales. Ceramic-based and/or ceramic-incorporated biomaterials are being biologically evaluated through several in vitro, in vivo and clinical tests.This book presents a review of recent research and developments in the pre-clinical and clinical use of bioceramics, its derivatives, and other bioceramic-based biomaterials and coatings in the fields of medicine and dentistry. An in-depth look into material processing, characterization, optimization, performance and cell/tissue interactions is presented with an overview of the potential of bioceramics in therapeutic agent and stem cell delivery, tissue engineering extending into the future perspectives of bioceramics, in an attempt to address the frequently asked questions relating to the development, characterization, modulation, optimization, and safe application of ceramic materials and ceramic-coated devices.

Work in the area of biomaterials and stem cell therapy has revealed great potential for many applications, from the treatment of localized defects and diseases to the repair and replacement of whole organs. Researchers have also begun to develop a better understanding of the cellular environment needed for optimal tissue repair and regeneration. Biomaterials and Stem Cells in Regenerative Medicine explores a range of applications for biomaterials and stem cell therapy and describes recent research on suitable cell scaffolds and substrates for tissue repair and reconstruction. Featuring contributions by experts in the field, the book explores important scientific and clinical aspects. It covers the basic science involved in structure and properties, techniques and technological innovations in processing and characterization, and applications of biomaterials and stem cells. Topics include:Polymeric systems for stem cell deliveryThe potential of membranes and porous scaffolds in tissue repair, including myocardial, periodontal, ophthalmic, and bone tissuesThe optimization of the interaction between stem cells and biomaterial substratesThe source and nature of stem cells for tissue engineering applicationsThe clinical translation of stem cell–based tissue engineering for regenerative medicineFrom fundamental principles to recent advances at the macro, micro, nano, and molecular scales, the book brings together current knowledge on biomaterials and stem cells in the context of regenerative medicine. It also stimulates discussion about future research directions. This unique book offers a valuable benchmark for the current status of clinically relevant research and development in stem cells and regenerative medicine. It bridges the gaps in experimental approaches and understanding among the materials science and engineering, biological sciences, and biomedical science and engineering communities, making it a valuable reference for graduate students, researchers, and practitioners working in the multidisciplinary field of biomedical research.

There are several well-known books on the market that cover biomaterials in a general way, but none provide adequate focus on the future of and potential for actual uses of emerging nanontechnology in this burgeoning field.Biomaterials: A Nano Approach is written from a multi-disciplinary point of view that integrates aspects of materials science and engineering, nanotechnology, bioengineering, and biosciences. The book fills a glaring void in the literature by providing a comprehensive discussion of biomaterials and a scientifically plausible extrapolation of likely scenarios in which nanotechnology could play a significant role. The authors introduce and examine basic concepts, processing methodologies, and techniques involved in the preparation and characterization of nanobiomaterials that are specific to biomedical applications. A Self-Contained Book Illustrating Past, Present, and Future Trends in BiomaterialsSpanning from the historical development of biomaterials to cutting-edge advances in the field, the text describes how basic concepts in nanotechnology are applied to the processing of novel nanobiomaterials, including nanostructured metals and alloys. With its illustrative examples and presentation of applications, this text offers a solid framework for understanding present and future trends of biomaterials in human healthcare systems. It is an ideal companion resource for students, researchers, and industrial scientists who specialize in biomaterials and nanobiomaterials.

Work in the area of biomaterials and stem cell therapy has revealed great potential for many applications, from the treatment of localized defects and diseases to the repair and replacement of whole organs. Researchers have also begun to develop a better understanding of the cellular environment needed for optimal tissue repair and regeneration. Biomaterials and Stem Cells in Regenerative Medicine explores a range of applications for biomaterials and stem cell therapy and describes recent research on suitable cell scaffolds and substrates for tissue repair and reconstruction. Featuring contributions by experts in the field, the book explores important scientific and clinical aspects. It covers the basic science involved in structure and properties, techniques and technological innovations in processing and characterization, and applications of biomaterials and stem cells. Topics include:Polymeric systems for stem cell deliveryThe potential of membranes and porous scaffolds in tissue repair, including myocardial, periodontal, ophthalmic, and bone tissuesThe optimization of the interaction between stem cells and biomaterial substratesThe source and nature of stem cells for tissue engineering applicationsThe clinical translation of stem cell–based tissue engineering for regenerative medicineFrom fundamental principles to recent advances at the macro, micro, nano, and molecular scales, the book brings together current knowledge on biomaterials and stem cells in the context of regenerative medicine. It also stimulates discussion about future research directions. This unique book offers a valuable benchmark for the current status of clinically relevant research and development in stem cells and regenerative medicine. It bridges the gaps in experimental approaches and understanding among the materials science and engineering, biological sciences, and biomedical science and engineering communities, making it a valuable reference for graduate students, researchers, and practitioners working in the multidisciplinary field of biomedical research.