Seeram Ramakrishna – författare

Nanofiber Composite Materials for Biomedical Applications presents new developments and recent advances in nanofiber-reinforced composite materials and their use in biomedical applications, including biomaterial developments, drug delivery, tissue engineering, and regenerative medicine.

Unlike more conventional titles on composite materials, this book covers the most innovative new developments in nanofiber-based composites, including polymers, ceramics, and metals, with particular emphasis on their preparation and characterization methodology.

Selected case studies illustrate new developments in clinical and preclinical use, making the information critical for the development of new medical materials and systems for use in human health care, and for the exploration of new design spaces based on these nanofibers. This book is essential reading for those working in biomedical science and engineering, materials science, nanoscience, biomedical nanotechnology, and biotechnology.

Covers innovative new developments in nanofiber composites, including polymers, ceramics, and metals with particular emphasis on their preparation and characterization methodology Deals with biomedical applications, including biomaterials developments, drug delivery, tissue engineering, and regenerative medicine Presents selected case studies on nanofiber composite materials in both clinical and preclinical use

Medical Devices and Regulations: Standards and Practices will shed light on the importance of regulations and standards among all stakeholders, bioengineering designers, biomaterial scientists and researchers to enable development of future medical devices.

Based on the authors' practical experience, this book provides a concise, practical guide on key issues and processes in developing new medical devices to meet international regulatory requirements and standards.

Provides readers with a global perspective on medical device regulations Concise and comprehensive information on how to design medical devices to ensure they meet regulations and standards Includes a useful case study demonstrating the design and approval process

Melt Electrospinning: A Green Method to Produce Superfine Fibers introduces the latest results from a leading research group in this area, exploring the structure, equipment polymer properties and spinning conditions of melt electrospinning. Sections introduce the invention of melt electrospinning, including the independent development of centrifugal melt electrospinning and upward melt electrospinning, discuss electro magnetization of melt and the testing method of fiber performance by means of different polymers and self-designed devices, cover simulation, and introduce principle methods and improvement measures of centrifugal melt electrospinning.

Presents melt electrospinning, a green nanofiber fabrication technology Introduces the invention of melt electrospinning, including centrifugal melt electrospinning and upward melt electrospinning Describes optimization techniques, electro magnetization of melt, testing methods, DPD simulation and improvement methods Provides a useful introduction to contemporary electrospinning research with a view to its many potential applications

Electrospun Polymers and Composites: Ultrafine Materials, High Performance Fibres and Wearables reviews the latest technological developments and innovations in electrospun polymers and composites, highlighting the multifunctionality of these ultrafine materials as high performance fibers. The book's chapters investigate a wide range of different electrospinning applications, including drug delivery, tissue scaffolding, fiber reinforcement and nanofiltration, with a particular focus on shape memory effect and the wearable characteristics of electrospun polymers and composites. This will be a valuable reference resource for research and for industrial communities working in the field of electrospinning.

Covers two important material systems in electrospun materials, including electrospun polymers and composites Emphasizes areas in shape memory effect and wearable features of electrospun polymers and composites Presents a multidisciplinary work that will attract a wide spectrum of readers in chemical engineering, biomedical engineering, chemistry, pharmacy, environmental science, materials science and engineering, as well as mechanical and electrical engineering

Innovative Processes and Materials in Additive Manufacturing explains game-changing interdisciplinary applications of recent research breakthroughs in additive manufacturing technology. The number of research publications addressing additive manufacturing has soared in recent years as a range of disciplines explore the possibilities that this technology can provide. This book acts as a bridge between this high-level research and the large number of academics and practitioners looking to additive manufacturing for innovative solutions, providing them with practical and approachable information. Applications in aerospace, automotive, medical, construction, and food industries are addressed, featuring technical details that will help successful implementation.

This unique book also provides broad coverage of the theory behind this emerging technology, including material development, as well as the technical details required for readers to investigate the novel applications of the involved methods for themselves.

Includes case studies from the aerospace, construction and medical industries Features innovations in the integration of additive manufacturing processes with other manufacturing technologies Identifies exciting routes for future research and application areas of additive manufacturing

3D Printing in Podiatric Medicine compiles an interdisciplinary range of scientific literature, laboratory developments, industrial implications and futuristic avenues in this field. The book provides recent developments and research breakthroughs in 3D printing in podiatric medicine, such as functionalized feedstock systems, smart products, process characteristics, modeling and optimization of printed systems and products, and industrial applications. It covers best practices for 3D printing methods to capture, document and validate challenges at the early stage of the design process.� The book's content then goes into mitigating design strategies to address these challenges without compromising the cost, safety and quality of the device.

This book supports new and emerging specializations and provides a comprehensive collection of technical notes, research designs, design methods and processes and case studies.

Includes coverage of the biomechanical behavior of feet, injuries and injury prevention using 3D printed customized orthosis Uses an amalgamation of CAD/CAM, reverse engineering and artificial intelligence with 3D printing in podiatric medicine Investigates plantar pressure using gait measurement technologies

Bioresorbable Polymers and their Composites: Characterization and Fundamental Processing for Pharmaceutical and Medical Device Development provides a holistic view of these unique materials and their usage in a range of biomedical applications. The book is evenly divided between fundamentals, processing methods and modeling approaches, and includes detailed coverage of a variety of applications, such as drug delivery, medical devices and wound healing. Key aspects including biocompatibility, biodegradability and toxicology are also thoroughly covered, enabling the reader to be fully informed when fabricating and utilizing their selected bioresorbable polymer.

This book is an interdisciplinary and important reference for researchers in the fields of materials science, biomedical engineering, pharmaceutical science and regenerative medicine, as well as R&D groups in the development of medical devices.

Introduces the reader to various processing and modeling techniques for bioresorbable polymers, including electrospinning, molecular and finite element modelingCovers a range of key bioresorbable composites, such as PCL, PLA/PLLA and PHA/PHB/PHBVExplores a wide selection of biomedical applications of bioresorbable polymers, from tissue engineering and stents, to biosensors and medical devices/implants

Sustainable manufacturing is a key component in the engineering industry, helping to decrease emissions, costs, and energy use. Through examining how to successfully implement sustainability within Industry 4.0, Sustainable Manufacturing: An Emergence in Industry 4.0 covers recent innovations in topics, including circular economy, supply chains, waste elimination, and recycling.This edited collection is a cutting-edge assessment of the barriers preventing the implementation of sustainable manufacturing in industry. Highlighting basic definitions and terminologies within sustainability and manufacturing, this book covers topics that include interactive design, remanufacturing, cleaner production, and optimization. It also features modern technologies currently revolutionizing the industry, such as robotics and 3D printing. Using case studies to illustrate success stories in which products have been created using sustainable processes, this book also includes technical notes and experimental results from a wide variety of international contributors.This book is relevant to anyone working in the mechanical engineering, manufacturing and industrial engineering, and materials science industries.

Sustainable manufacturing is a key component in the engineering industry, helping to decrease emissions, costs, and energy use. Through examining how to successfully implement sustainability within Industry 4.0, Sustainable Manufacturing: An Emergence in Industry 4.0 covers recent innovations in topics, including circular economy, supply chains, waste elimination, and recycling.This edited collection is a cutting-edge assessment of the barriers preventing the implementation of sustainable manufacturing in industry. Highlighting basic definitions and terminologies within sustainability and manufacturing, this book covers topics that include interactive design, remanufacturing, cleaner production, and optimization. It also features modern technologies currently revolutionizing the industry, such as robotics and 3D printing. Using case studies to illustrate success stories in which products have been created using sustainable processes, this book also includes technical notes and experimental results from a wide variety of international contributors.This book is relevant to anyone working in the mechanical engineering, manufacturing and industrial engineering, and materials science industries.

A comprehensive exposition of micro and nanofiber forming, this text provides a unified framework of all these processes (melt and solution blowing, electrospinning, and so on) and describes their foundations, development and applications. It provides an up-to-date, in-depth physical and mathematical treatment, and discusses a wide variety of applications in different fields, including nonwovens, energy, healthcare and the military. It further highlights the challenges and outstanding issues from an interdisciplinary perspective of science and technology, incorporating both fundamentals and applications. Ideal for researchers, engineers and graduate students interested in the formation of micro and nanofibers and their use in functional smart materials.

A cutting-edge look at the application of micro and nanotechnologies in regenerative medicineThe area at the interface of micro/nanotechnology and stem cells/tissue engineering has seen an explosion of activity in recent years. This book provides a much-needed overview of these exciting developments, covering all aspects of micro and nanotechnologies, from the fundamental principles to the latest research to applications in regenerative medicine.Written and edited by the top researchers in the field, Micro and Nanotechnologies in Engineering Stem Cells and Tissues describes advances in material systems along with current techniques available for cell, tissue, and organ studies. Readers will gain tremendous insight into the state of the art of stem cells and tissue engineering, and learn how to use the technology in their own research or clinical trials. Coverage includes: Technologies for controlling or regulating stem cell and tissue growthVarious engineering approaches for stem cell, vascular tissue, and bone regenerationThe design and processing of biocompatible polymers and other biomaterialsCharacterization of the interactions between cells and biomaterialsUnrivaled among books of this kind, Micro and Nanotechnologies in Engineering Stem Cells and Tissues is the ultimate forward-looking reference for researchers in numerous disciplines, from engineering and materials science to biomedicine, and for anyone wishing to understand the trends in this transformative field.

This book acts as a self-contained resource for understanding the current technological advancement of biomaterials towards tissue engineering applications.  It covers impact of biomaterials at different length scales such as macro/micro/nano/ level and offers extensive discussion on cell-biomaterial interactions with illustrative examples. This resource offer a multi-disciplinary approach for the adaptability of integrated biomaterials in tissue repair and reconstruction.

This cutting edge book provides all the important aspects dealing with the basic science involved in materials in biomedical technology, especially structure and properties, techniques and technological innovations in material processing and characterizations, as well as the applications.The volume consists of 12 chapters written by acknowledged experts of the biomaterials field and covers a wide range of topics and applications including: The different types of nanobiomaterialsHow to generate porous biomaterials for tissue engineeringCalcium phosphate-based biomaterials intended for mineralized tissue regenerative applicationsNanocrystalline form of calcium phosphatesDesign and fabrication of SiO2 nanoparticlesNew kinds of titanium alloy implantsInjectable growth factor system based on bone morphogenetic proteinsImpedance sensing of biological processes in mammalian cellsHydrogels-based implantable glucose sensorsMolecular design of multifunctional polymers for gene transfectionHydrogels and their potential biomedical applicationsHybrid biomaterials with high mechanical and biological properties

Work in the area of biomaterials and stem cell therapy has revealed great potential for many applications, from the treatment of localized defects and diseases to the repair and replacement of whole organs. Researchers have also begun to develop a better understanding of the cellular environment needed for optimal tissue repair and regeneration. Biomaterials and Stem Cells in Regenerative Medicine explores a range of applications for biomaterials and stem cell therapy and describes recent research on suitable cell scaffolds and substrates for tissue repair and reconstruction. Featuring contributions by experts in the field, the book explores important scientific and clinical aspects. It covers the basic science involved in structure and properties, techniques and technological innovations in processing and characterization, and applications of biomaterials and stem cells. Topics include:Polymeric systems for stem cell deliveryThe potential of membranes and porous scaffolds in tissue repair, including myocardial, periodontal, ophthalmic, and bone tissuesThe optimization of the interaction between stem cells and biomaterial substratesThe source and nature of stem cells for tissue engineering applicationsThe clinical translation of stem cell–based tissue engineering for regenerative medicineFrom fundamental principles to recent advances at the macro, micro, nano, and molecular scales, the book brings together current knowledge on biomaterials and stem cells in the context of regenerative medicine. It also stimulates discussion about future research directions. This unique book offers a valuable benchmark for the current status of clinically relevant research and development in stem cells and regenerative medicine. It bridges the gaps in experimental approaches and understanding among the materials science and engineering, biological sciences, and biomedical science and engineering communities, making it a valuable reference for graduate students, researchers, and practitioners working in the multidisciplinary field of biomedical research.

There are several well-known books on the market that cover biomaterials in a general way, but none provide adequate focus on the future of and potential for actual uses of emerging nanontechnology in this burgeoning field.Biomaterials: A Nano Approach is written from a multi-disciplinary point of view that integrates aspects of materials science and engineering, nanotechnology, bioengineering, and biosciences. The book fills a glaring void in the literature by providing a comprehensive discussion of biomaterials and a scientifically plausible extrapolation of likely scenarios in which nanotechnology could play a significant role. The authors introduce and examine basic concepts, processing methodologies, and techniques involved in the preparation and characterization of nanobiomaterials that are specific to biomedical applications. A Self-Contained Book Illustrating Past, Present, and Future Trends in BiomaterialsSpanning from the historical development of biomaterials to cutting-edge advances in the field, the text describes how basic concepts in nanotechnology are applied to the processing of novel nanobiomaterials, including nanostructured metals and alloys. With its illustrative examples and presentation of applications, this text offers a solid framework for understanding present and future trends of biomaterials in human healthcare systems. It is an ideal companion resource for students, researchers, and industrial scientists who specialize in biomaterials and nanobiomaterials.

Work in the area of biomaterials and stem cell therapy has revealed great potential for many applications, from the treatment of localized defects and diseases to the repair and replacement of whole organs. Researchers have also begun to develop a better understanding of the cellular environment needed for optimal tissue repair and regeneration. Biomaterials and Stem Cells in Regenerative Medicine explores a range of applications for biomaterials and stem cell therapy and describes recent research on suitable cell scaffolds and substrates for tissue repair and reconstruction. Featuring contributions by experts in the field, the book explores important scientific and clinical aspects. It covers the basic science involved in structure and properties, techniques and technological innovations in processing and characterization, and applications of biomaterials and stem cells. Topics include:Polymeric systems for stem cell deliveryThe potential of membranes and porous scaffolds in tissue repair, including myocardial, periodontal, ophthalmic, and bone tissuesThe optimization of the interaction between stem cells and biomaterial substratesThe source and nature of stem cells for tissue engineering applicationsThe clinical translation of stem cell–based tissue engineering for regenerative medicineFrom fundamental principles to recent advances at the macro, micro, nano, and molecular scales, the book brings together current knowledge on biomaterials and stem cells in the context of regenerative medicine. It also stimulates discussion about future research directions. This unique book offers a valuable benchmark for the current status of clinically relevant research and development in stem cells and regenerative medicine. It bridges the gaps in experimental approaches and understanding among the materials science and engineering, biological sciences, and biomedical science and engineering communities, making it a valuable reference for graduate students, researchers, and practitioners working in the multidisciplinary field of biomedical research.

This book provides a concise and comprehensive introduction of polymer membranes' preparation, functionalization and applications in biotechniques including affinity membrane chromatography, membrane-based biosensor and membrane-based bioreactor.Following an introduction to the general concept of membrane separation in Chapter 1, preparation of polymeric membranes is discussed in Chapter 2. The book then describes in Chapter 3 membrane surface activation, which is a key step in ligand immobilizations. Chapter 4 focuses on ligand immobilization techniques and the organic chemistries behind them. Chapter 5 introduces the application of affinity membrane chromatography. Finally, in Chapter 6, membranes used in biosensors and gas sensors, enzymatic membranes used as biosensor, and membrane biosensor for waste water treatment will be discussed.A novel filter medium, i.e. nonwoven nanofiber membrane, and its preparation method, i.e. electrospinning technique, are also introduced in this book.

This book provides a concise and comprehensive introduction of polymer membranes' preparation, functionalization and applications in biotechniques including affinity membrane chromatography, membrane-based biosensor and membrane-based bioreactor.Following an introduction to the general concept of membrane separation in Chapter 1, preparation of polymeric membranes is discussed in Chapter 2. The book then describes in Chapter 3 membrane surface activation, which is a key step in ligand immobilizations. Chapter 4 focuses on ligand immobilization techniques and the organic chemistries behind them. Chapter 5 introduces the application of affinity membrane chromatography. Finally, in Chapter 6, membranes used in biosensors and gas sensors, enzymatic membranes used as biosensor, and membrane biosensor for waste water treatment will be discussed.A novel filter medium, i.e. nonwoven nanofiber membrane, and its preparation method, i.e. electrospinning technique, are also introduced in this book.

Many years of cumulative research has been conducted on the usage of fiber-reinforced composites for biomedical application, but no one source exists where this topic is dealt with systematically. This book addresses polymer composites applied to bioengineering in a comprehensive manner.For potential applications to be successful, full advantage must be taken of the materials properties and the manufacturing techniques to meet the needs of biomedical application. This book focuses on fiber-based composites applied to bioengineering. It addresses three main areas. First, it presents a comprehensive survey of biocomposites from the existing literature in various medical applications, paying particular attention to hard-tissue-related implants. Second, mechanical designs and manufacturing aspects of various fibrous polymer matrix composites are described. The third area concerns examples of the design and development of several medical devices and implants using polymer composites.

Many years of cumulative research has been conducted on the usage of fiber-reinforced composites for biomedical application, but no one source exists where this topic is dealt with systematically. This book addresses polymer composites applied to bioengineering in a comprehensive manner.For potential applications to be successful, full advantage must be taken of the materials properties and the manufacturing techniques to meet the needs of biomedical application. This book focuses on fiber-based composites applied to bioengineering. It addresses three main areas. First, it presents a comprehensive survey of biocomposites from the existing literature in various medical applications, paying particular attention to hard-tissue-related implants. Second, mechanical designs and manufacturing aspects of various fibrous polymer matrix composites are described. The third area concerns examples of the design and development of several medical devices and implants using polymer composites.

This book covers the state-of-the-art on electrospun materials for the use of filters for water remediation, ion-exchange membranes and affinity membranes for the capture of selected chemical and biochemical species, as well as filtering applications covering air treatment, defense and protective applications, and oil-water separation.

​Current Trends in Biomanufacturing focuses on cutting-edge research regarding the design, fabrication, assembly, and measurement of bio-elements into structures, devices, and systems.The field of biomaterial and biomanufacturing is growing exponentially in order to meet the increasing demands of for artificial joints, organs and bone-fixation devices. Rapid advances in the biological sciences and engineering are leading to newer and viable resources, methods and techniques that may providing better quality of life and more affordable health care services.The book covers the broad aspects of biomanufacturing, including:synthesis of biomaterials;implant coating techniques;spark plasma sintering;microwave processing; andcladding, powder metallurgy and electrospinning.The contributors illustrate the recent trends of biomanufacturing, highlighting theimportant aspects of biomaterial synthesis, and their use as feedstock of fabrication technologies and their characterization, along with their clinical practices. Current Trends in Biomanufacturing updates researchers and scientists the novelties and techniques of the field, as it summarises numerous aspects of biomanufacturing, including synthesis of biomaterials, fabrication of biomedical structures, their in-vivo/ in-vitro, mechanical analysis and associated ISO standards.

Furthermore, producing the feedstock using waste materials will help to reduce the cost of the processing material, productivity and eco-friendliness of this manufacturing technology.

Furthermore, producing the feedstock using waste materials will help to reduce the cost of the processing material, productivity and eco-friendliness of this manufacturing technology.

This book provides readers with the comprehensive insights of the recent research breakthroughs in additive, subtractive, and hybrid technologies.

This book provides readers with the comprehensive insights of the recent research breakthroughs in additive, subtractive, and hybrid technologies. Further, the book examines incomparable design and manufacturing independences, as well as strategies to upgrade the product performance characteristics through collaborating additive and subtractive technologies. Indeed, the intrinsic benefits and limitations of both additive and subtractive manufacturing technologies could be merged to obtain appreciable hybridizations. The editorial team members and contributors to Additive, Subtractive, and Hybrid Technologies are highly motivated experts committed to and the advance of hybrid manufacturing technologies.

This book covers the state-of-the-art on electrospun materials for the use of filters for water remediation, ion-exchange membranes and affinity membranes for the capture of selected chemical and biochemical species, as well as filtering applications covering air treatment, defense and protective applications, and oil-water separation.

This book provides the key fundamental principles, classifications, recent developments, as well as different applications of additive manufacturing technologies. A comprehensive overview of the different classes is given, covering polymer-based, metal-based and ceramic-based systems. Special topics such as bioprinting and 4D printing are also introduced. The authors discuss the technological aspects of additive manufacturing in a very clear and understandable way, delivered with the help of self-illustrating artworks. This book is particularly designed to suit the curriculum requirements of undergraduate and graduate students enrolled in Mechanical Engineering, Material Science, Product Design and Development, Biomedical Engineering, Automobile and Aerospace Engineering, and other closely related domains. Manufacturing professionals working in similar fields may also wish to read it as a refresher and to catch up on recent advances.

This book provides the key fundamental principles, classifications, recent developments, as well as different applications of additive manufacturing technologies. A comprehensive overview of the different classes is given, covering polymer-based, metal-based and ceramic-based systems. Special topics such as bioprinting and 4D printing are also introduced. The authors discuss the technological aspects of additive manufacturing in a very clear and understandable way, delivered with the help of self-illustrating artworks. This book is particularly designed to suit the curriculum requirements of undergraduate and graduate students enrolled in Mechanical Engineering, Material Science, Product Design and Development, Biomedical Engineering, Automobile and Aerospace Engineering, and other closely related domains. Manufacturing professionals working in similar fields may also wish to read it as a refresher and to catch up on recent advances.