Ranbir Chander Sobti – författare

Exploration in Laboratory Animal Sciences Understanding Life Phenomena updates our knowledge about the newer technologies such as molecular biology, genomics including sequencing, proteomics, transcriptomics, cell culture, stem cell culture, transgenesis and their translation to understand systematics and phylogeny of laboratory animals at molecular level. In seven sections Exploration in Laboratory Animal Sciences Understanding Life Phenomena resolves issues of conservation, applications in environment monitoring, production of drugs and others. Comparative research has enabled use of domestic animal models that translate the advances in basic biosciences to the schemes for human welfare including medicine. Molecular geneticists are unravelling the complexities of mammalian genes and the field of biotechnology is maturing at a fast pace. Additionally, research focused on immunology and animal behavior offer new insight into ways of enhancing animal welfare. The rise in consumption of animal proteins in addition to the challenges of sustaining our natural resources has given animal scientists a vast array of opportunities to engage in integrative systems-based research for meeting the challenges that behold us.

Exploration in Laboratory Animal Sciences Understanding Life Phenomena also discusses the manipulation of animals as factories for the production of safe foods, drugs, and sensors and others to meet the contemporary challenges faced by mankind in the new world order created by pandemic of Covid 19. It also includes several chapters on the causation and management of certain diseases and impact of microbes on life.

Provides insight to newer and futuristic technologies to understand disease process and drug design by animal models Addresses a wide variety of species and covers a wide variety of topics (such as animal species, the laboratory setting, regulatory guidelines, and ethical considerations) to fully prepare for work with all types of animals Gives a perspective on laboratory animal use that allows to explain the benefits of animal use as required by veterinary technology program accreditation procedure Includes examples of animal bio-technological techniques (including stem cell and tissue engineering) for their applications to humanity Offers new insight into ways of enhancing animal welfare by the inclusion of research results focused on immunology and laboratory animal behavior

Molecular Biomarkers in Cancer Detection and Monitoring of Therapeutics: Volume Two: Diagnostic and Therapeutic Applications discusses how molecular biomarkers are used to determine predisposition, facilitate detection, improve treatment and offer prevention guidelines for different cancers. It focuses on novel diagnostic techniques based on molecular biomarkers and their impact on treatment, covering different cancer types such as tumors in the nervous system, head and neck, oral and GI tractor, lung, breast, gastric system, leukemia and urogenital tract cancers. For each type, the book discusses the best diagnostic techniques and therapeutic approaches, thus helping readers easily identify the best solution for each case. This is a valuable resource for cancer researchers, oncologists, graduate students and other members of the biomedical field who are interested in the potential of biomarkers in cancer research. Provides up-to-date information on current molecular biomarkers research for cancer Presents new diagnostic techniques using biomarkers that can leverage quicker results that can be essential for patient's survivorship Discusses several novel therapeutics applied to specific cancer types, such as head and neck, oral, GI tract, breast, lung and hepatocellular carcinomas

Biomarkers in Cancer Detection and Monitoring of Therapeutics, Volume One, Discovery and Technologies discusses how molecular biomarkers are used to determine predisposition, facilitate detection, improve treatment and offer prevention guidelines for different cancer types. This first volume in the series focuses on techniques and approaches recently developed to assist in the decision of which biomarker to use for specific conditions. Topics covered include circulating tumor cells and circulating tumor DNA, exomes, tumor microenvironment, gene editing, artificial intelligence and robotics. In addition, the book discusses the development and applications of organoids and precision medicine.This book will be a valuable resource for cancer researchers, oncologists, graduate students and members of the biomedical field who are interested in the potential of biomarkers in cancer research.Provides up-to-date information on current molecular biomarkers research for cancerPresents basic research aspects and novel technologies applied in the discovery of new biomarkersDiscusses several technologies, including artificial intelligence, robotics, data mining, gene editing, omics and their applicability for specific cancer types

Molecular Medicine and Biomedical Research in the Era of Precision Medicine: New Technologies and Personalized Drug Therapies for Patient Care provides researchers with an extensive overview of recent advances in molecular biology impacting the development of targeted therapies. The book delivers insights into the pathobiological and pathogenetic mechanisms of various diseases, providing a detailed study of the latest personalized interventions to be implemented across such conditions. It covers a range of technologies, including RNA-sequencing, AI, Machine Learning, gene therapy, omics and nanotechnology, delving into their clinical applications across various diseases.The book also tackles targeted treatments of different disease types, including acute, chronic, infectious and noncommunicable diseases. Future perspectives are also covered, providing an in-depth study across molecular medicine, drug discovery and delivery, disease diagnosis and prevention, and therapeutic interventions, and acting as an invaluable interdisciplinary reference for researchers across the biomedical sciences.

One Planet, One Health, One Future: Charting a Course for Global Wellness, Environmental Resilience, and Sustainable Food Systems provides a comprehensive synthesis of research findings, best practices, and emerging trends across the interconnected fields of health, environment, and agriculture, serving as a valuable reference for those seeking to deepen their understanding of interdisciplinary issues. Chapters explore topics such as precision public health, artificial intelligence in environmental monitoring, and regenerative agriculture practices. The book presents cutting-edge insights and innovative solutions that can inform and inspire the readers and contribute to advancing knowledge in their respective fields. Written by experts in diverse fields such as epidemiology, ecology, agronomy, and public health, the book offers multidimensional insights and perspectives for researchers, policymakers, and practitioners working at the intersection of public health, environmental science, and agricultural studies.Explores the interconnected realms of health, environment, and agriculture, providing understanding of pressing issues such as climate change, infectious diseases, sustainable farming, and global health governanceOffers perspectives from diverse fields such as data science, conservation biology, indigenous knowledge, and medical technology, sharing a holistic understanding of our planet's challenges and opportunitiesPresents insights and innovative solutions throughout the book, empowering individuals, communities, and policymakers to make informed decisions and meaningful steps towards a sustainable, equitable future for both humanity and the planet

Public and Environmental Health: Shaping Tomorrow for a Sustainable Future offers an in-depth exploration of the latest developments, strategies, and research in these intertwined fields, providing readers with a comprehensive understanding of how to improve health outcomes through innovative approaches and informed public policy. Sections address how individuals and communities can make informed health decisions for better health outcomes, present the myriad of challenges the environment poses, including climate change, and how global cooperation, policy interventions, and sustainable practices can help improve outcomes for communities across the world. Additional content details how surveillance and epidemiological research are foundational to public health at both a national and international level, allowing authorities to respond promptly to threats, allocate resources effectively, and implement targeted interventions. Written by experts from across the globe, this book is ideal for public health administrators, researchers, students, and NGOs involved in public health programs and the environment.Presents existing knowledge on emerging technologies to predict and evaluate concerns arising from climate, demographic, and geological changesDiscusses contemporary issues on organ-based health such as brain, eyes, ears, nose, heart, kidney, and bones respective to treatment and preventionCovers additional topics on aging and the potential for future pandemics

Advanced Technologies for Disease Intervention: Innovations Across Precision Medicine, Nutrition and Holistic Therapies, Two Volume Set investigates current and emerging advances in disease detection, diagnosis, treatment and prevention, and how molecular medicine and biotechnology have contributed to this changing landscape. Volume One focuses on sustainable health practices through biotechnology, exploring traditional health systems, diagnostic innovations, and integrative therapies. Key topics include: the role of traditional medicine and practices in sustainable health; contemporary and emerging technologies such as aptamer diagnostics, telemedicine, nanomaterials and AI in healthcare, and much more.Volume Two then delves deeper into emerging technologies for disease intervention, focusing on drug development, delivery systems, nutrition, and natural products for health. Themes explored here include: developments and trends in drug discovery; drug repurposing; contemporary drug delivery systems; phototherapeutics; personalized drug delivery; innovations in vaccine development; the role of nutraceuticals in disease prevention; and the use of natural products and herbal interventions for sustainable health.Provides an in-depth compendium of emerging biotechnological therapies and diagnostic innovations, covering the latest advances in molecular medicine and biopharmaceutical researchDelivers interdisciplinary perspectives, fostering collaboration across various research fields to enhance patient care strategiesConsiders both traditional therapies and cutting-edge innovations in the pursuit of sustainable health, from yoga practices, nutraceuticals and natural supplements, to AI, regenerative medicine, recombinant antigens, and genome editing technologies

Probiotics: A Comprehensive Exploration of Health Benefits and Innovation explores the potential of probiotics and their fundamental role in human health and disease prevention. The book offers a thorough understanding of how beneficial microorganisms can enhance overall well-being and potentially transform treatment approaches across multiple disciplines. The first section lays the groundwork by exploring the fundamentals of probiotics, prebiotics, and their interactions with the human microbiome, while the second section examines the role of probiotics in disease prevention and management, highlighting their impact on conditions such as diabetes, obesity, and mental health.The third section discusses specialized applications of probiotics in women's health, pediatrics, and geriatrics, as well as their innovative uses in skin care and nutrition. Finally, the fourth section investigates the future potential of probiotics in synthetic biology, in personalized health, and in combatting antibiotic resistance. With contributions from a diverse group of experts in the field, the book serves as an interdisciplinary resource for researchers, clinicians, and industry professionals eager to explore the therapeutic potential and benefits of probiotics.Provides comprehensive coverage of probiotics for diverse health conditionsOffers in-depth regulatory insights, emphasizing global regulatory standards, safety, and quality controlPresents future perspectives on next-generation probiotics and cutting-edge developments

This reference book extensively examines the important role of biotechnology in tackling the global challenge of achieving zero hunger. The book delves into cutting-edge advancements and challenges in food biotechnology, crop improvement, genetic engineering, and the utilization of genetically modified organisms (GMOs) in sustainable agriculture. It provides a detailed examination of biotechnological interventions aimed at enhancing the nutritional content of crops, increasing agricultural productivity, and ensuring food security. Furthermore, the book explores the application of biotechnological techniques in improving animal-based foods, including advancements in animal breeding, genetics, and disease resistance. The chapters also address the integration of traditional breeding approaches with biotechnology for developing healthier and more productive crops. Additionally, the book introduces approaches for reduction of food waste through technological solutions, and the use of automation and robotics in food processing. This book is useful for researchers, academicians, and professionals of biotechnology, agriculture, food science, and sustainability.Key Features:Covers cutting-edge biotechnological technologies for sustainable agriculture, providing solutions to address global hunger and achieve the goal of zero hungerDiscusses various crop improvement techniques, including genetic engineering and genetically modified organismsFocuses on biotechnological interventions for enhancing crop productivity and nutritional value to improve food availability and qualityPresents a detailed discussion of crop protection strategies and disease resistance mechanismsProvides a thorough examination of advanced technologies for improving animal-based foods and technology-based artificial meatExamines the application of biotechnological techniques in developing innovative food systems for reducing food waste

This book reviews the important role of biotechnological innovations in achieving sustainable development goals and conserving global biodiversity. It presents the latest biotechnological techniques used to identify and characterize various groups of plants and animals, such as genomic tools for animal identification, and DNA barcoding for precise plant characterization. It also reviews the utility of proteomics and metabolomics in enhancing our understanding of diverse species. The book also discusses responsible development and sustainable utilization of bioresources, including strategies for conserving and managing bioresources, bioprospecting for novel biodiscoveries, and sustainable agricultural practices to preserve agrobiodiversity. Further, the book addresses the pressing challenges faced by biodiversity, including the far-reaching effects of climate change, the threat posed by invasive species, the consequences of pollution on biodiversity degradation, and the interplay between diseases and biodiversity decline. Toward the end, the book analyzes the impact of environmental degradation on biodiversity and explores emerging technologies in biodiversity conservation, focusing on genetically modified organisms (GMOs). The book will interest scientists, researchers, policymakers, environmentalists, academics, and students involved in biotechnology, ecology, genetics, and conservation biology.Key Features:Discusses cutting-edge biotechnological innovations for biodiversity conservationPresents cutting-edge biotechnological techniques for identifying and characterizing selected groups of plants and animalsAddresses critical environmental challenges such as climate change, invasive species, and pollution

Environmental sustainability is one of the biggest issues faced by the mankind. Rapid & rampant industrialization has put great pressure on the natural resources. To make our planet a sustainable ecosystem, habitable for future generations & provide equal opportunity for all the living creatures we not only need to make corrections but also remediate the polluted natural resources. The low-input biotechnological techniques involving microbes and plants can provide the solution for resurrecting the ecosystems. Bioremediation and biodegradation can be used to improve the conditions of polluted soil and water bodies. Green energy involving biofuels have to replace the fossil fuels to combat pollution & global warming. Biological alternatives (bioinoculants) have to replace harmful chemicals for maintaining sustainability of agro-ecosystems. The book will cover the latest developments in environmental biotech so as to use in clearing and maintaining the ecosystems for sustainable future.

?This book presents drug repurposing strategies to combat infectious diseases and cancer. It also explores the databases for drug repositioning, summarizes the approaches taken for drug repositioning, and highlights and compares their characteristics and challenges.

?This book presents drug repurposing strategies to combat infectious diseases and cancer. It also explores the databases for drug repositioning, summarizes the approaches taken for drug repositioning, and highlights and compares their characteristics and challenges.

This book explores the various  techniques used to study and understand microbes, from traditional methods to modern technologies. It covers key areas like analyzing microbial genes, proteins, and metabolites, as well as advanced tools like AI and high-tech imaging. Each chapter introduces different approaches, including genomic sequencing, RNA analysis, and high-throughput screening, helping readers gain a deeper insight into microbial processes. The book is an ideal resource for researchers, students, and professionals in microbiology, biotechnology, and related fields looking to stay updated with cutting-edge methods in microbial research.

The book explores the pivotal role of science and technology in achieving the sustainable development goals (SDGs) outlined in the agenda 2030 for sustainable development.

The book explores the pivotal role of science and technology in achieving the sustainable development goals (SDGs) outlined in the agenda 2030 for sustainable development. It emphasizes the importance of integrating science and technology into developing strategies to promote a sustainable and prosperous global future. The book highlights the universal acceptance of the SDGs by United Nations member states, subnational governing bodies, and international organizations. It emphasizes that all stakeholders, including governmental bodies, private enterprises, and civil society, have a responsibility to contribute to the achievement of the SDGs. Science, technology, and innovation are identified as the three pillars essential for achieving the SDGs.The book emphasizes the critical role of science and technology in addressing complex issues such as climate change, biodiversity loss, resource depletion, poverty reduction, health, education, gender equality, clean energy, sustainable cities, responsible consumption, and climate action. It helps to develop innovative solutions to promote economic growth, social inclusion, and environmental sustainability. And provide the necessary knowledge and tools to develop effective policies and strategies in these areas.Furthermore, the book highlights the potential of science and technology in promoting innovation and entrepreneurship, leading to the creation of new businesses and industries that align with sustainable development principles. This fosters economic growth, job creation, and environmental sustainability. It advocates for continued investment in science and technology and their integration into development strategies. The book aims to provide insights into the role of traditional and emerging areas of science and technology in meeting the goals outlined in the SDG document, with a specific focus on India.The book serves as a great source of information for researchers, teachers in basic and applied sciences /social sciences research and policymakers.

Flow cytometry is a state-of-the-art technology that is widely used in biological research and clinical diagnostics. It is a high-throughput platform that allows the quantification, differentiation, and functional study of cells or cell like particles in suspension. Various cell components can be targeted with fluorescently labelled antibodies or fluorescent dyes to allow measurement and analysis of the physical, chemical, and biological properties of individual cells within homogenous or heterogeneous populations.Since its commercialization more than five decades ago, flow cytometry has advanced and become an very important analytical tool in translational research. With the advancement of instrument technology, an increasing number of fluorescent dyes, and an expanding range of monoclonal antibodies, the applications of flow cytometry in applied research continue to grow.The use of multiparametric flow cytometry in translational research provides the ability to rapidly identify different cell populations and to simultaneously measure multiple parameters of single cells for efficiently assessing immune status, decrease/increase of specific immune cell populations, cell activation status, etc. of different cells in preclinical and clinical studies.The primary goal of any research work is to take research results from the "bench to-bed and back". The use of flow cytometry in applied research advances the development of new diagnostic tests or drugs for cancer treatment, immune monitoring, etc. that help in patient care.Today, every biological scientist needs to have basic knowledge of flow cytometry in order to utilise this technology properly in their own research and to understand other’s research work. The present book has been designed to give the knowledge of flow cytometry and its applications to the researchers and teachers. It will allow the readers to utilize the technology in an appropriate way in their research work. This book has describing various applications of flow cytometry like cell health monitoring, immunophenotyping, cell sorting, stem cell characterization, micro-vesicle analysis etc.

Flow cytometry is a state-of-the-art technology that is widely used in biological research and clinical diagnostics. It is a high-throughput platform that allows the quantification, differentiation, and functional study of cells or cell like particles in suspension. Various cell components can be targeted with fluorescently labelled antibodies or fluorescent dyes to allow measurement and analysis of the physical, chemical, and biological properties of individual cells within homogenous or heterogeneous populations.Since its commercialization more than five decades ago, flow cytometry has advanced and become an very important analytical tool in translational research. With the advancement of instrument technology, an increasing number of fluorescent dyes, and an expanding range of monoclonal antibodies, the applications of flow cytometry in applied research continue to grow.The use of multiparametric flow cytometry in translational research provides the ability to rapidly identify different cell populations and to simultaneously measure multiple parameters of single cells for efficiently assessing immune status, decrease/increase of specific immune cell populations, cell activation status, etc. of different cells in preclinical and clinical studies.The primary goal of any research work is to take research results from the "bench to-bed and back". The use of flow cytometry in applied research advances the development of new diagnostic tests or drugs for cancer treatment, immune monitoring, etc. that help in patient care.Today, every biological scientist needs to have basic knowledge of flow cytometry in order to utilise this technology properly in their own research and to understand other’s research work. The present book has been designed to give the knowledge of flow cytometry and its applications to the researchers and teachers. It will allow the readers to utilize the technology in an appropriate way in their research work. This book has describing various applications of flow cytometry like cell health monitoring, immunophenotyping, cell sorting, stem cell characterization, micro-vesicle analysis etc.

This book discusses the role of science and technology in forging a sustainable and harmonious world.

This book discusses the role of science and technology in forging a sustainable and harmonious world. It delves into new horizons in healthcare, food security, climate change, energy, sustainable transportation, role of computational and data sciences in sustainability, and mental health and aims to cultivate innovative solutions that benefit both the planet and its inhabitants. The second volume is inspired by a unified objective: preserving our planet, fostering universal well-being, and envisioning a world where collective efforts drive positive change through an exploration of conventional and emerging technologies. The book chapters enrich the global discourse on sustainability, steering us toward a resilient and healthier future.With every chapter authored by dedicated experts, this book stands as a testament to the commitment to a better world and serves as a great resource for researchers, environmentalists, and students.

The book delves into the field of biotechnology and its crucial role in achieving sustainable developmental goals. With a focus on promoting good health and well-being, the book explores various aspects of biotechnological advancements, their applications, and their potential to address pressing global challenges. The first section of the book sets the stage by discussing the evolution and revolutions in healthcare technologies. It covers topics such as the use of advanced technologies in predictive medicine and the management of diseases across different organs. The chapter on health and aging issues sheds light on the importance of biotechnological interventions in promoting healthy aging. Continuing the exploration of health-related issues, the book addresses emerging technologies in drug development, design, and delivery systems, including the innovative approach of drug repurposing. It further discusses transformative technologies in reproductive health and neonatology, emphasizing the significant impact biotechnological advancements have on maternal and child health. The chapter on vaccines and vaccination strategies highlights the role of biotechnology in developing effective immunization approaches and combating infectious diseases. Additionally, the book showcases innovative technologies aimed at tackling pandemic diseases, providing insights into the potential of biotechnological interventions during global health crises. Then the focus shifts to the broader domain of sustainability and zero hunger. It explores various innovative approaches to food biotechnology, including the production of healthier and more productive crops and the development of technology-based artificial meats. The book also discusses the reduction of food waste through technology-based interventions, emphasizing the importance of sustainable food systems and the improvement of nutritional values in foods. Moving on to the conservation of biological diversity, the book sheds lighton the significant relationship between biodiversity and sustainable development. It explores biotechnological innovations in identifying and characterizing selected groups of plants and animals, emphasizing the need for their sustainable utilization and then further highlighting the potential of biotechnology in discovering valuable resources and drawing inspiration from nature. The book also addresses the challenges faced by biodiversity and the threats posed by environmental degradation, underscoring the importance of emerging technologies in conservation efforts. Finally, the book delves into the realm of environment sustainability, showcasing biotechnological innovations in environmental bioremediation, biofuels, and green fuels. It addresses the impacts of climate change on biotic and abiotic systems and explores the role of biotechnology in mitigating these challenges. The chapters on biofertilizers and biopesticides highlight the significance of biotechnology in promoting organic farming practices and reducing the environmental impact of agriculture.The book offers a comprehensive and insightful overview of the advancements, applications, and potential of biotechnology in achieving sustainable developmental goals. It serves as a valuable resource for researchers, professionals, and policymakers working towards a sustainable and healthier future for all.

This book highlights the clinical applications of biomarkers are extensive for cancer risk assessment, screening and early detection of cancer, accurate diagnosis, patient prognosis, prediction of response to therapy, and cancer surveillance and monitoring response.