Issues in Toxicology – serie
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55 produkter
Comet Assay in Toxicology
Av Alok Dhawan, Diana Anderson
Inbunden, 2009
2574 kr
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The vast number of chemicals existing or being added into the environment, have globally aroused great concern regarding their adverse effects in human population. Development and validation of sensitive and better test systems which can assess the adverse effects of chemicals at an early stage for …
Hair in Toxicology
An Important Bio-Monitor
Inbunden, 2005
2658 kr
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Hair in Toxicology: An Important Biomonitor is the first book of its kind devoted exclusively to in-depth analysis of the hair shaft as an important tool for a diverse range of scientific investigations. This authoritative book combines contributions from experts in academic, governmental and …
Bile Acids
Toxicology and Bioactivity
Av Gareth J Jenkins, Laura Hardie
Inbunden, 2008
1412 kr
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Bile acids are increasingly being seen as extremely important carcinogenic agents in cancers of the bile duct, liver, colon, rectum, and oesophagus. They are essential agents involved in lipid digestion and absorption in mammals, however, they also play wide-ranging roles in a variety of disease …
Male-mediated Developmental Toxicity
Av Diana Anderson, Martin H Brinkworth
Inbunden, 2007
2251 kr
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The issue of male germ line mutagenesis and the effects on developmental defects in the next generation has become increasingly high profile over recent years. Mutations are thought to be becoming more prevalent as a result of: exposure to chemicals in the environment, anti cancer regimes that use …
Regulatory Toxicology in the European Union
Inbunden, 2018
2963 kr
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Consumer and environmental protection depend on the careful regulation of all classes of chemicals. Toxicology is the key science used to evaluate safety and so underpins regulatory decisions on chemicals. With the growing body of EU legislation involved in chemical regulation, there is a …
Chemical Health Threats
Assessing and Alerting
Av Raquel Duarte-Davidson, Tom Gaulton m. fl.
Inbunden, 2018
3285 kr
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Chemical health threats can have impacts across national borders and so may be more effectively tackled by international cooperation than by individual governments acting alone. As such, in November 2013, the European Union published the EU Decision for Serious Cross Border Threats to Health …
Nanotoxicology
Experimental and Computational Perspectives
Av Alok Dhawan, Diana Anderson m. fl.
Inbunden, 2017
3075 kr
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The rapid expansion of the nanotechnology field raises concerns, like any new technology, about the toxicity and environmental impact of nanomaterials. This book addresses the gaps relating to health and safety issues of this field and aims to bring together fragmented knowledge on nanosafety. Not …
Oxidative Stress and Redox Signalling in Parkinson’s Disease
Av Rodrigo Franco, Jonathan A Doorn m. fl.
Inbunden, 2017
3357 kr
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Parkinson's Disease is the second most common neurodegenerative disorder affecting millions of people worldwide. In order to find neuroprotective strategies, a clear understanding of the mechanisms involved in the dopaminergic death of cells that progresses the disease is needed. Oxidative stress …
Comet Assay in Toxicology
Av Diana Anderson, Alok Dhawan
Inbunden, 2016
3357 kr
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Concerns about the adverse effects of chemicals present in the environment have created a need for better systems to assess their potential consequences on human health. One potential solution is the versatile and state-of-the-art Comet assay. Simple, sensitive, rapid and visual, this modern …
Big Data in Predictive Toxicology
Av Daniel Neagu, Andrea-Nicole Richarz
Inbunden, 2019
3357 kr
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The rate at which toxicological data is generated is continually becoming more rapid and the volume of data generated is growing dramatically. This is due in part to advances in software solutions and cheminformatics approaches which increase the availability of open data from chemical, biological …
Computational Systems Pharmacology and Toxicology
Av Rudy J Richardson, Dale E Johnson
Inbunden, 2017
2919 kr
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The network approaches of systems pharmacology and toxicology serve as early predictors of the most relevant screening approach to pursue both in drug discovery and development and ecotoxicological assessments. Computational approaches have the potential to improve toxicological experimental …
Human Stem Cell Toxicology
Inbunden, 2016
3170 kr
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Toxicity against tissue stem cells (TSCs) is a major problem in drug development and environmental health science. Despite their essential function in all human cellular tissues, the nature of tissue stem cells is not fully understood. The small fraction of stem cells in tissues and the lack of …
Chemical Warfare Toxicology
Complete Set
Av Horst Thiermann, John Jenner m. fl.
2016
6292 kr
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Despite ongoing efforts to prohibit the production, storage and use of chemical warfare agents recent world events highlight the enduring threat to the population from these agents. Research efforts in various countries have resulted in novel insights into chemical warfare toxicology that has …
Ecotoxicology and Genotoxicology
Non-traditional Terrestrial Models
Inbunden, 2017
2835 kr
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The potential impact of anthropogenic pollutants such as agrochemicals on the environment is of global concern. Increasing use of certain compounds can result in contamination of food, water and atmospheric systems and in order to combat this pollution it is important to be able to accurately …
Formaldehyde
Exposure, Toxicity and Health Effects
Inbunden, 2018
2797 kr
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Formaldehyde is virtually ubiquitous in the modern environment due to its cost-effective nature, its use in resin formation, and its preservative properties. Though formaldehyde is necessary for many products and processes important to the world’s economy, this economic dependence on formaldehyde …
Micronucleus Assay in Toxicology
Av Siegfried Knasmueller, Michael Fenech
Inbunden, 2019
3190 kr
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Concerns about the adverse health effects of chemicals and radiation present in the environment and at workplaces have created the need for better detection systems to assess their potential to cause DNA damage in humans and other organisms across ecosystems. The Micronucleus Assay in Toxicology is …
Ecotoxicology and Genotoxicology
Complete Set
2017
7063 kr
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The potential impact of anthropogenic pollutants such as agrochemicals on the environment is of global concern. Increasing use of certain compounds can result in contamination of food, water and atmospheric systems and in order to combat this pollution it is important to be able to accurately …
Nanoparticle–Protein Corona
Biophysics to Biology
Av Ashutosh Kumar, Alok Dhawan
Inbunden, 2019
3078 kr
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Nanoparticles have numerous biomedical applications including drug delivery, bone implants and imaging. A protein corona is formed when proteins existing in a biological system cover the nanoparticle surface. The formation of a nanoparticle–protein corona, changes the behaviour of the nanoparticle, …
Challenges in Endocrine Disruptor Toxicology and Risk Assessment
Av Alberto Mantovani, Alexandra Fucic
Inbunden, 2020
3012 kr
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Insight into the role of hormones, particularly estrogen and testosterone, in health and disease etiology – including interactions with other hormone pathways – has dramatically changed. Estrogen and androgen receptors, with their polymorphisms, are key molecules in all tissues and are involved in …
Amphibian Species in Environmental Risk Assessment Strategies
Av Marcelo L Larramendy, Guillermo Eli Liwszyc
Inbunden, 2023
2833 kr
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With the expansion of human settlements and the environmental changes brought about by human activity and pollutants, toxicology and risk assessment of amphibian species has become increasingly of interest to toxicologists involved in environmental research. This book focuses specifically on …
Fish Species in Environmental Risk Assessment Strategies
Av Guillermo Eli Liwszyc, Marcelo L Larramendy
Inbunden, 2024
2897 kr
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With the expansion of human settlements and the environmental changes brought on by human activity and pollutants, toxicology and risk assessment of piscine species is becoming increasingly of interest to scientists involved in environmental research and connected disciplines. This book focuses …
Marsupial and Placental Mammal Species in Environmental Risk Assessment Strategies
Av Marcelo L Larramendy, Guillermo Eli Liwszyc
Inbunden, 2022
2716 kr
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With the expansion of human settlements and the environmental changes brought on by human activity and pollutants toxicology and risk assessment of mammal species is becoming increasingly of interest to toxicologists involved in environmental research. This book focuses specifically on …
Bisphenol A
A Multi-modal Endocrine Disruptor
Inbunden, 2022
2245 kr
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Bisphenol A (BPA) is a high production volume endocrine-disrupting chemical present in numerous consumer products. Extensive use of BPA has led to wide-spread contamination in the air, soil, and water, leading to ubiquitous human exposure. Research into BPA has grown exponentially over the past ten …
Neurotransmitters and Toxicology
Inbunden, 2024
2835 kr
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Neurotransmitters are usually considered to be endogenous substances that are released from neurons, act on receptor sites that are typically present on membranes of postsynaptic cells and produce a functional change in the properties of the target cell. They are essential features of the nervous …
Bird and Reptile Species in Environmental Risk Assessment Strategies
Av Guillermo Eli Liwszyc, Marcelo L Larramendy
Inbunden, 2023
2645 kr
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With the expansion of human settlements and the environmental changes brought on by human activity and pollutants, toxicology and risk assessment of bird and reptile species is becoming increasingly of interest to toxicologists involved in environmental research. This book focuses specifically on …
Male-mediated Developmental Toxicity
Av Diana Anderson, Khaled Habas
Inbunden, 2024
2709 kr
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Germ cells have a unique and critical role as the conduit for hereditary information. The issue of male germline mutagenesis and the effects on developmental defects in the next generation has become increasingly high profile in recent years. Understanding the mechanisms by which the germline is …
Perspectives and Challenges of Hair Analysis
Av Pascal Kintz, Alberto Salomone m. fl.
Inbunden, 2023
3236 kr
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Hair analysis is a reliable and widely used tool to evaluate drug exposure in many fields, including workplace testing, drug abuse history and withdrawal control, post-mortem toxicology, doping control, therapeutic drug monitoring of pharmaceuticals and even environmental exposure to toxic agents. …
In Silico Toxicology
Principles and Applications
Inbunden, 2010
2847 kr
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In Silico methods to predict toxicity have become increasingly important recently, particularly in light of European legislation such as REACH and the Cosmetics Regulation. They are also being used extensively worldwide e.g. in the USA, Canada, Japan and Australia. In assessing the risk that a …
Environmental Cardiology
Pollution and Heart Disease
Inbunden, 2010
2269 kr
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Although it is widely recognized that environmental factors such as smoking, diet, exercise, and socioeconomic status affect the risk of cardiovascular disease, recent work showing the effects of other environmental factors provides a more complete assessment of the situation. This view has emerged …
Silver in Healthcare
Its Antimicrobial Efficacy and Safety in Use
Inbunden, 2010
2245 kr
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Silver in healthcare has many different facets and since the early concepts of microbiology of the 1880's, has been developed from usage in surgical clips, staples, foil wound dressings and surgical implants, to the widespread and clinically effective antiseptic wound dressings, sutures, catheters, …
