Nutritional Neurosciences – serie

This book comprehensively reviews the proteins associated with neurodevelopmental disorders, including autism spectrum disorder (ASD) and attention deficit hyperactivity disorder (ADHD). It also discusses the interactions of the associated-proteins, like bromodomain-containing proteins (BCPs), kinases, synaptic proteins, scaffolding proteins, transcriptional factors, and DNA-binding proteins at the subcellular and molecular levels. The book also explores the potential of these proteins as a druggable target and a biomarker in the neurodevelopmental disorders. The book further explores the recent advancements in understanding the important role of epigenetic factors in predisposition to these diseases. Lastly, it presents genetic factors that lead to variation in gene expression in these diseases, disorders management via diet intervention and the future potential of stem cell therapy.

This book comprehensively reviews the proteins associated with neurodevelopmental disorders, including autism spectrum disorder (ASD) and attention deficit hyperactivity disorder (ADHD). It also discusses the interactions of the associated-proteins, like bromodomain-containing proteins (BCPs), kinases, synaptic proteins, scaffolding proteins, transcriptional factors, and DNA-binding proteins at the subcellular and molecular levels. The book also explores the potential of these proteins as a druggable target and a biomarker in the neurodevelopmental disorders. The book further explores the recent advancements in understanding the important role of epigenetic factors in predisposition to these diseases. Lastly, it presents genetic factors that lead to variation in gene expression in these diseases, disorders management via diet intervention and the future potential of stem cell therapy.

This book comprehensively reviews the relationship between micronutrients and brain in health and diseases. It explains the relationship between micronutrients and brain functions, neurogenesis, and cognitive functions. The book also explores the relationship between micronutrients and brain disorders including depression, epilepsy, PD, and Autism. It further explores the recent advancements in understanding the important role of micronutrients as therapeutics in various brain disorders like TBI and AD. Lastly, it presents an overview of micronutrients as neuroprotective agents along with the main principles of nutrigenomics.

This book comprehensively reviews the relationship between micronutrients and brain in health and diseases. It explains the relationship between micronutrients and brain functions, neurogenesis, and cognitive functions. The book also explores the relationship between micronutrients and brain disorders including depression, epilepsy, PD, and Autism. It further explores the recent advancements in understanding the important role of micronutrients as therapeutics in various brain disorders like TBI and AD. Lastly, it presents an overview of micronutrients as neuroprotective agents along with the main principles of nutrigenomics.

This book provides the latest research on the role of nutrients in the prevention and treatment of neurological disorders. It discusses dietary supplements and dietary restrictions for combating neurological disorders, including Alzheimer’s disease, Parkinson’s disease, stroke, and epilepsy. The book also explains the impact of different nutrients such as herbal products, algae, micronutrients in stimulating the brain and central nervous system during abnormal functions. It covers the effect of the nutrients on the function of neurotransmitters, their stimulatory effect in autism, dementia, Alzheimer’s, and other neuropathological states. The book also defines the mechanistic effects of neuroprotective and psycho protective effects of natural food in repairing brain damage. This book is essential reading for neuroscientists and neurologists, and healthcare professionals.

This book provides the latest research on the role of nutrients in the prevention and treatment of neurological disorders. It discusses dietary supplements and dietary restrictions for combating neurological disorders, including Alzheimer’s disease, Parkinson’s disease, stroke, and epilepsy. The book also explains the impact of different nutrients such as herbal products, algae, micronutrients in stimulating the brain and central nervous system during abnormal functions. It covers the effect of the nutrients on the function of neurotransmitters, their stimulatory effect in autism, dementia, Alzheimer’s, and other neuropathological states. The book also defines the mechanistic effects of neuroprotective and psycho protective effects of natural food in repairing brain damage. This book is essential reading for neuroscientists and neurologists, and healthcare professionals.

Dr. Mohammed Salama is Atlantic senior fellow for Equity in brain health at the Global Brain Health Institute (GBHI) and Associate professor at the Institute of Global Health and Human Ecology at the American University in Cairo (AUC). He established the first Translational Neuroscience Unit in Egypt. Mohamed’s collaborative research led to establishing the Egyptian Network for Neurodegenerative Disorders Mohamed was selected as a SOT Global Senior Scholar in 2013 and Translational/bridging awardee in 2016. He was awarded by Parkinson’s and Movement Disorders Foundation (PMDF) for his continued research in neurodegeneration. Recently, Mohamed and his colleagues succeeded in drafting the first Reference Egyptian Genome and collaborating with other colleagues to start a national cohort (A Longitudinal Study of Egyptian Health Aging [AL-SEHA]). ​

Dr. Mohammed Salama is Atlantic senior fellow for Equity in brain health at the Global Brain Health Institute (GBHI) and Associate professor at the Institute of Global Health and Human Ecology at the American University in Cairo (AUC). He established the first Translational Neuroscience Unit in Egypt. Mohamed’s collaborative research led to establishing the Egyptian Network for Neurodegenerative Disorders Mohamed was selected as a SOT Global Senior Scholar in 2013 and Translational/bridging awardee in 2016. He was awarded by Parkinson’s and Movement Disorders Foundation (PMDF) for his continued research in neurodegeneration. Recently, Mohamed and his colleagues succeeded in drafting the first Reference Egyptian Genome and collaborating with other colleagues to start a national cohort (A Longitudinal Study of Egyptian Health Aging [AL-SEHA]). ​

This book provides an overview of bidirectional communication between gut-microbiome-brain, pathways, nutrients, and metabolites that are involved in microbiota gut-brain axis (MGBA) interactions. Further it reviews the relevance of this axis in the neurological disorders and potential therapeutic interventions, involving gut microbiome or probiotics and prebiotics which can ameliorate the neurological disorders. The book examines the role of gut microbiota in the establishment and hemostasis of innate immune response and explores the possibility of development of microbiome-targeted therapeutic interventions. Notably, the book discusses the role of the gut microbiota and immune system on the maintenance of brain functions and the development of neurological disorders. It also highlights the recent advances in improving neurological diseases by phytochemicals, prebiotics and probiotics. This book is useful for researchers working in neuropharmacology, Clinical Research, toxicology, neurodegeneration, and stroke biology.

This book provides an overview of bidirectional communication between gut-microbiome-brain, pathways, nutrients, and metabolites that are involved in microbiota gut-brain axis (MGBA) interactions. Further it reviews the relevance of this axis in the neurological disorders and potential therapeutic interventions, involving gut microbiome or probiotics and prebiotics which can ameliorate the neurological disorders. The book examines the role of gut microbiota in the establishment and hemostasis of innate immune response and explores the possibility of development of microbiome-targeted therapeutic interventions. Notably, the book discusses the role of the gut microbiota and immune system on the maintenance of brain functions and the development of neurological disorders. It also highlights the recent advances in improving neurological diseases by phytochemicals, prebiotics and probiotics. This book is useful for researchers working in neuropharmacology, Clinical Research, toxicology, neurodegeneration, and stroke biology.

The book comprehensively reviews the role of nutrition in psychiatric disorders. The book further explores the recent advancements in understanding the important role of nutrients as therapeutics in various psychiatric disorders.

The book comprehensively reviews the role of nutrition in psychiatric disorders. It provides mechanistic insights into the effects of nutrition on metabolic pathways, mitochondrial nutrients, neurodegeneration and CNS disorders, cell signaling, and neuronal functions.  The book further highlights the role of diet in preventing and treating mental health and modifying drug treatment effects. Further, it explores the relationship between nutrition and psychiatric disorders, including depression, autism, anxiety, Attention-Deficit / Hyperactivity Disorder, and OCD. The book further explores the recent advancements in understanding the important role of nutrients as therapeutics in various psychiatric disorders. Lastly, it presents an overview of nutrients as neuroprotective agents along with the main principles of nutrigenomics. The book is essential reading for neuroscientists interested interest in food therapeutic strategies.

This book explores the molecular mechanisms of iron hemostasis in the brain and discusses the cognitive and behavioral implications of iron deficiency. It presents the effect of iron dysregulation on neurophysiological mechanisms. The book provides an overview of iron metabolism and homeostasis at the cellular level and its regulation at the mRNA translation level. It emphasizes the importance of iron for brain development in fetal and early life in preterm infants. Further, it presents iron metabolism as a therapeutic target for novel pharmacological treatment against neurodevelopmental diseases and neurodegenerative disorders. It discusses the role of iron deficiency in sleep disorders and offers diagnosis and treatment of iron-related CNS diseases. Finally, it relates dysregulated expression of iron-related genes in brain tumors.​​

This book explores the molecular mechanisms of iron hemostasis in the brain and discusses the cognitive and behavioral implications of iron deficiency. It presents the effect of iron dysregulation on neurophysiological mechanisms. The book provides an overview of iron metabolism and homeostasis at the cellular level and its regulation at the mRNA translation level. It emphasizes the importance of iron for brain development in fetal and early life in preterm infants. Further, it presents iron metabolism as a therapeutic target for novel pharmacological treatment against neurodevelopmental diseases and neurodegenerative disorders. It discusses the role of iron deficiency in sleep disorders and offers diagnosis and treatment of iron-related CNS diseases. Finally, it relates dysregulated expression of iron-related genes in brain tumors.​​

Offering a culturally inclusive and integrative approach, the book bridges functional foods, personalized nutrition, and mental wellness, providing groundbreaking insights into complex issues such as substance use disorders and chronic pain.

This book addresses all aspects of diet in preventing and managing Alzheimer's disease. It highlights the role of specific dietary components like polyphenols, flavonoids, catechins, lignans etc., along with various dietary patterns in improving neuronal health and mitigating the symptoms of disease.Role of diet and its impact on overall health and well-being have emerged as promising areas of research. The comprehensive and holistic approach offered in the book provides a thorough scientific view of dietary components in preventing, managing or delaying the onset of Alzheimer’s disease (AD). By incorporating the most recent scientific research and evidence-based practices, this book presents the necessary knowledge and tools to improve cognitive health and enhance quality of life through dietary choices. In addition, this book also gives an overview of the latest scientific contributions in the field of the pathophysiology of this disease and how this understanding helps in developing newer therapeutic interventions.With high-quality images, chemical structures, and well-structured tables, the book aims to present intricate information in an accessible and interesting manner. By incorporating research case studies, the book not only educates but also motivates readers to take tangible steps towards effective dietary management.Thus this book serves as a crucial guide for utilizing the potential of nutrition in the battle against Alzheimer's disease. It is mainly targeted at nutritionists, post graduate students, researchers and biochemists working in the area of Alzheimer's.

This book presents an extensive exploration of how medicinal mushrooms can enhance brain health, boost cognitive function, and support overall well-being.With growing interest in natural nootropics, adaptogens, and holistic wellness, medicinal mushrooms are gaining recognition as one of the most potent functional foods for cognitive longevity. Backed by scientific research and centuries of traditional wisdom, this book unveils the powerful neuroprotective, adaptogenic, and immune-boosting properties of fungi like Lion’s Mane, Reishi, Cordyceps, and Chaga. This book delves deep into the bioactive compounds found in medicinal mushrooms such as beta-glucans, hericenones, erinacines, and triterpenes and explains how they work to protect neurons, reduce inflammation, enhance nerve regeneration, and balance stress hormones. Apart from mechanistic studies, the book also highlights easy and practical ways to incorporate mushrooms into daily routine—through supplements, teas, tinctures, and delicious recipes.Thus this book aims to be a practical guide to unlock the full potential of fungi for mind and body. By bridging the gap between ancient healing traditions and modern neuroscience, this book serves as an essential reading for neuroscientists, nutritionists, health-conscious individuals, biohackers, and anyone eager to explore nature’s most powerful brain-boosting superfoods.

This book discusses the role of artificial intelligence in neurological disorders, including, alleviating movement disorders, psychiatric disorders, diagnosis of neurological and neurodegenerative disorders, dementia, neuronal cancer, neuronal Infections, and brain diseases.

This book discusses the role of artificial intelligence in neurological disorders, including, alleviating movement disorders, psychiatric disorders, diagnosis of neurological and neurodegenerative disorders, dementia, neuronal cancer, neuronal Infections, and brain diseases. It explores applications of artificial intelligence in the early diagnosis, prognosis, and development of new therapies against neurodegenerative disorders. This book also provides cutting-edge research using AI for studying neuroimage analysis, toward the discovery of new biological pathways and systems implicated in dementia and related diseases. It also reviews AI-based interventions in depression research and treatment. The chapter also examines the potential benefits of using AI to help manage depression, from improved access to coordinated care. This book is an essential source for students, researchers, academicians, and neurologists aiming to understand AI-based approaches for the diagnosis, treatment, and prevention of neurological disorders.

The book explores the intricate relationship between nutrition, brain function, and psychiatric disorders. In the final section, the book delves into the nutritional treatment of psychiatric disorders, including the psychopharmacology of psychiatric disorders and food intake, and multidisciplinary approaches to psychiatric treatment..

The book provides a thorough examination of the crucial connection between diet, cognitive aging, and dementia using a multidisciplinary approach.

The book provides a thorough examination of the crucial connection between diet, cognitive aging, and dementia using a multidisciplinary approach. It dives into the complex area of neurology, illuminating different forms of dementia, their underlying pathophysiology, and the risk factors related to them. It explains the symptoms, diagnoses, and therapies for dementia. The book explores the effects of dietary elements like protein, micronutrients, and superfoods, demonstrating their potential to protect cognitive function. Additionally, it discusses how critical vitamins like D and B12, natural antioxidants, and trace minerals affect dementia risk and development. The book explains the use of conventional herbal medicine as a supplementary strategy to dementia therapy, evaluating its potential efficacy and safety. The book provides evidence-based advice to professionals, physicians, researchers, nutritionists, and healthcare professionals to understand the nutritional requirements to control dementia.

This book offers an insightful exploration into the relationship between diet and Multiple Sclerosis (MS), aiming to address a crucial question: Can dietary interventions serve as effective preventative and therapeutic measures for patients with MS? Delving into this question, the book examines various nutritional components and regimens, shedding light on their potential impacts on the progression, relapse rate, and development of MS. It offers readers valuable insights into how dietary choices can influence the management of this condition.Backed up by evidence gathered from review and clinical trial papers, the book discusses the role of vitamins such as A, B, and D, as well as dietary supplements like caffeine, carnitine, and lipoic acid in benefiting patients with MS. Particular attention is given to the significance of vitamin D in lowering the risk of developing MS and its immunomodulatory effects on the inflammatory processes associated with the disease.In parallel, the book also addresses the detrimental effects of diets such as the Western or high salt diet (HSD) on MS prognosis, emphasizing how these dietary regimens can harm the gut microbiome and exacerbate inflammatory responses, ultimately promoting demyelination of the central nervous system (CNS). The book then explores alternative dietary approaches that confer a protective effect on the gut microbiome and the CNS, including whole grain, fasting, Mediterranean, and ketogenic diets.This comprehensive resource is an essential reading for patients with MS seeking to understand the potential impacts of diet on their overall health, as well as healthcare professionals and researchers interested in exploring dietary interventions for MS management.

This book offers an insightful exploration into the relationship between diet and Multiple Sclerosis (MS), aiming to address a crucial question: Can dietary interventions serve as effective preventative and therapeutic measures for patients with MS? Delving into this question, the book examines various nutritional components and regimens, shedding light on their potential impacts on the progression, relapse rate, and development of MS. It offers readers valuable insights into how dietary choices can influence the management of this condition.Backed up by evidence gathered from review and clinical trial papers, the book discusses the role of vitamins such as A, B, and D, as well as dietary supplements like caffeine, carnitine, and lipoic acid in benefiting patients with MS. Particular attention is given to the significance of vitamin D in lowering the risk of developing MS and its immunomodulatory effects on the inflammatory processes associated with the disease.In parallel, the book also addresses the detrimental effects of diets such as the Western or high salt diet (HSD) on MS prognosis, emphasizing how these dietary regimens can harm the gut microbiome and exacerbate inflammatory responses, ultimately promoting demyelination of the central nervous system (CNS). The book then explores alternative dietary approaches that confer a protective effect on the gut microbiome and the CNS, including whole grain, fasting, Mediterranean, and ketogenic diets.This comprehensive resource is an essential reading for patients with MS seeking to understand the potential impacts of diet on their overall health, as well as healthcare professionals and researchers interested in exploring dietary interventions for MS management.

The book provides a comprehensive exploration of the relationship between nutrition and traumatic brain injury (TBI). Divided into two sections, the book covers various aspects of TBI, from its biomechanics and pathophysiological changes to evidence-based clinical guidelines and experimental models.Section I covers the background of TBI, including the definition and biomechanics of TBI, an understanding of pathophysiological changes that occur in the brain, and the importance of evidence-based clinical guidelines for effective TBI management. The section also delves into experimental models of TBI and the role of biomarkers in diagnosing and assessing TBI. Furthermore, it explores early feeding guidelines following TBI, emphasizing the significance of nutrition in the recovery process.Section II focuses on the connection between nutrition and TBI. It examines the concept of resilience and nutri-protection against TBI prior to the injury, highlighting strategies to enhance the brain's ability to withstand trauma. The book then explores the role of various nutrients and dietary components in TBI, such as antioxidants, branched-chain amino acids, choline, creatine, ketogenic diet, magnesium, polyunsaturated fatty acids (EPA and DHA), polyphenols, vitamin D, and zinc. Each topic is explored in depth, considering their impact on TBI outcomes and potential therapeutic applications.Furthermore, this section delves into nutritional interventions for TBI management. It addresses the selection of appropriate nutritional interventions and mechanistic targets for effective treatment. The section also explores the integration of nutrition into clinical practice guidelines for TBI and the emerging field of nutrigenomics, which investigates the interaction between nutrition and the genetic factors involved in TBI. Additionally, the section discusses the role of pharmacognosy in TBI research and provides nutritional recommendations for TBI management, considering the diverse needs of individuals affected by TBI.The book contributes to advancing the understanding and management of TBI by exploring the background, highlighting the importance of nutrition, and offering insights into nutritional interventions with potential implications for both preventive and therapeutic approaches.The book is a great resource for students and brain/neuroscience researchers.