Human iPSC-derived Disease Models for Drug Discovery

Häftad, Engelska, 2024

Del i serien Handbook of Experimental Pharmacology

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Beskrivning

Since their development a decade ago, human induced pluripotent stem cells (iPSC) have revolutionized the study of human disease, given rise to regenerative medicine technologies, and provided exceptional opportunities for pharmacologic research.

Produktinformation

Utgivningsdatum:2024-11-24
Mått:155 x 235 x 18 mm
Vikt:578 g
Format:Häftad
Språk:Engelska
Serie:Handbook of Experimental Pharmacology
Antal sidor:332
Förlag:Springer International Publishing AG
ISBN:9783031423512

Utforska kategorier

Biokemisk teknik inom Naturvetenskap och teknik
Regenerativ medicin inom Medicin
Biovetenskap inom Naturvetenskap och teknik

Innehållsförteckning

Part 1 General considerations.- Human iPS for clinical applications and cellular products.- 3D-printed iPS disease models.- Part 2 CNS iPSC and organoids.- iPS-derived neurons and brain organoids from patients (brain).- iPS-derived RGCs (eye).- iPS-derived glia (brain).- iPSC to model blood-brain barrier endothelial cells.- Part 3 iPSC-derived nociceptive neurons.- IPSC-based peripheral nerve modeling.- Part 4 Non-neuronal specialized cell types.- iPSC-based drug screening of differentiated cardiomyocyte subtypes.- iPSC-based cardiac disease modeling: from cell to tissue.- iPSC-derived corneal endothelial cell.- iPSC-derived trabecular meshwork (eye).- iPSC for in vitro disease modeling of diabetes.