Yang Song - Böcker

A disease is defined as rare if the prevalence is fewer than 200,000 in the United States. It is estimated that there are more than 7,000 rare diseases, which collectively affect 30 million Americans or 10% of the US population. This diverse and complex disease area poses challenges for patients, caregivers, regulators, drug developers, and other stakeholders. This book is proposedto give an overview of the common issues facing rare disease drug developers, summarize challenges specific to clinical development in small populations, discuss drug development strategies in the evolving regulatory environment, explain generation and utilization of different data and evidenceinside and beyond clinical trials, and use recent examples to demonstrate these challenges and the development strategies that respond to the challenges.Key Features:• Rare disease.• Drug development.• Innovative clinical trial design.• Regulatory approval.• Real-world evidence.

New media has brought constant evolution to professional journalism practices and news genres. Online news practices challenge the occupational jurisdiction of journalism with a multiplicity of conflicting and competing journalistic ideals. In order to prepare journalism students to meet the demands of online journalism today, journalism schools have developed courses that emphasize journalistic practice on online news platforms and tools, such as Twitter, WordPress.com, Soundslides Plus, etc.Drawing on the theoretical lens of digital literacies, Multimedia News Storytelling as Digital Literacies problematizes the emphasis on transmission of certain professional values and news formats without raising students’ critical awareness that there can be diversity of values. Methodologically, the present study proposes a genre-aware, semiotic-aware, critical framework that aims at analyzing digital literacies required and practiced by online journalists. It simultaneously encompasses dimensions of professional culture, professional practices, and abstraction of instantiated meaning making via multimodal semiotic resources.Multimedia News Storytelling as Digital Literacies is ideal for courses in journalism and mass communication, curriculum studies, and digital literacies. The book is a valuable resource for online journalism educators, journalism students, and online journalism practitioners.

Collaborative innovation networks are cyberteams of motivated individuals, and are self-organizing emergent social systems with the potential to promote health, happiness and individual growth in real-world work settings.This book describes how to identify and nurture collaborative innovation networks in order to shape the future working environment and pave the way for health and happiness, and how to develop future technologies to promote economic development, social innovation and entrepreneurship. The expert contributions and case studies presented also offer insights into how large corporations can creatively generate solutions to real-world problems by means of self-organizing mechanisms, while simultaneously promoting the well-being of individual workers. The book also discusses how such networks can benefit startups, offering new self-organizing forms of leadership in which all stakeholders are encouraged to collaborate in the development of new products.

Collaborative innovation networks are cyberteams of motivated individuals, and are self-organizing emergent social systems with the potential to promote health, happiness and individual growth in real-world work settings.This book describes how to identify and nurture collaborative innovation networks in order to shape the future working environment and pave the way for health and happiness, and how to develop future technologies to promote economic development, social innovation and entrepreneurship. The expert contributions and case studies presented also offer insights into how large corporations can creatively generate solutions to real-world problems by means of self-organizing mechanisms, while simultaneously promoting the well-being of individual workers. The book also discusses how such networks can benefit startups, offering new self-organizing forms of leadership in which all stakeholders are encouraged to collaborate in the development of new products.

This book constitutes the second part of the refereed proceedings of the International Conference on Life System Modeling and Simulation, LSMS 2014, and of the International Conference on Intelligent Computing for Sustainable Energy and Environment, ICSEE 2014, held in Shanghai, China, in September 2014. The 159 revised full papers presented in the three volumes of CCIS 461-463 were carefully reviewed and selected from 572 submissions. The papers of this volume are organized in topical sections on advanced neural network theory and algorithms; advanced evolutionary computing theory and algorithms, such as particle swarm optimization, differential evolution, ant colonies, artificial life, artificial immune systems and genetic algorithm; fuzzy, neural, and fuzzy-neuro hybrids; intelligent modeling, monitoring, and control of complex nonlinear systems; intelligent modeling and simulation of climate change; communication and control for distributed networked systems.

This book explores China's hukou system, by which individuals are registered in a specific geographic region, and the prospects for reform. The history of the hukou system and its instrumental role in Chinese urbanization and labor markets is explained, and readers get a sense of what issues are prioritized by Chinese policymakers as they contemplate reform or change to this system, from hukou-based labor market discrimination, inequality of opportunity, multi-dimensional poverty of rural migrants, the public health consequences of non-hukou migration, and old age insurance for migrants without hukous. The author concludes with a stirring and practical call for hukou reform, articulating a cost-benefit model and providing an array of policy suggestions. This book will interest scholars of Chinese society, demographics and future urbanization.