Understanding Life – serie

Forensic DNA analysis plays a central role in the judicial system. A DNA sample can change the course of an investigation with immense consequences. Because DNA typing is recognized as the epitome of forensic science, increasing public awareness in this area is vital. Through several cases, examples and illustrations, this book explains the basic principles of forensic DNA typing, and how it integrates with law enforcement investigations and legal decisions. Written for a general readership, Understanding Forensic DNA explains both the power and the limitations of DNA analysis. This book dispels common misunderstandings regarding DNA analysis and shows how astounding match probabilities such as one-in-a-trillion are calculated, what they really mean, and why DNA alone never solves a case.

One in two of us will develop cancer at some point in our lives and yet many of us don't understand how cancers arise. How many different kinds of cancer are there? What treatments are available? What does the future hold in terms of developing new therapies? This book demystifies cancer by explaining the underlying cell and molecular biology in a clear and accessible style. It answers the questions commonly asked about cancer such as what causes cancer and how cancer develops. It explains how DNA makes proteins and how mutations can corrupt those proteins. It also gives an overview of current therapies and how treatments may advance over the next decades, as well as explaining what actions we can take to help prevent cancer developing. Understanding Cancer is an accessible and engaging introduction to cancer biology for any interested reader.

Infertility can have devastating physical, emotional and financial effects on people affected. It is a common problem, but can be hard to talk about, and hard to understand. In this concise book, Dr Kovacs, a reproductive gynaecologist who has spent the past 40 years working with patients facing fertility problems, focuses on and unpicks key misconceptions. In his clear explanations, he covers the basic physiology of conceiving, and describes the areas that have to be explored for those who have not yet been able to conceive. Specific chapters cover the three major problem areas: lack of releasing eggs, sperm problems, and abnormalities of the female passages. Treatment options are discussed for each of these areas, including technical details and a brief readable overview of their history. The many ways of parenting which are now available are also detailed. This is a recommended read for couples wanting to conceive, their friends and families, and anyone who wants to understand fertility.

The human species is very young, but in a short time it has acquired some striking, if biologically superficial, variations across the planet. As this book shows, however, none of those biological variations can be understood in terms of discrete races, which do not actually exist as definable entities. Starting with a consideration of evolution and the mechanisms of diversification in nature, this book moves to an examination of attitudes to human variation throughout history, showing that it was only with the advent of slavery that considerations of human variation became politicized. It then embarks on a consideration of how racial classifications have been applied to genomic studies, demonstrating how individualized genomics is a much more effective approach to clinical treatments. It also shows how racial stratification does nothing to help us understand the phenomenon of human variation, at either the genomic or physical levels.

Natural selection, as introduced by Charles Darwin in the Origin of Species (1859), has always been a topic of great conceptual and empirical interest. This book puts Darwin's theory of evolution in historical context showing that, in important respects, his central mechanism of natural selection gives the clue to understanding the nature of organisms. Natural selection has important implications, not just for the understanding of life's history - single-celled organism to man - but also for our understanding of contemporary social norms, as well as the nature of religious belief. The book is written in clear, non-technical language, appealing not just to philosophers, historians, and biologists, but also to general readers who find thinking about important issues both challenging and exciting.

Since the identification of the first cases of the coronavirus in December 2019, there has been a significant amount of confusion regarding the origin and spread of the so-called 'coronavirus', SARS-CoV-2, and the cause of the disease COVID-19. Conflicting messages from the media and officials across different countries and organizations, the abundance of disparate sources of information, unfounded conspiracy theories on the origins of the virus, unproven therapies, and inconsistent public health measures, have all served to increase anxiety in the population. Where did the virus come from? How is it transmitted? How does it cause disease? Is it like flu? What is a pandemic? In this concise and accessible introduction, a leading expert provides answers to these commonly asked questions. This revised and updated edition now also covers how the virus mutates, how important these mutations are, how vaccines work, and what we can expect in the near and long-term future.

Human life, and how we came to be, is one of the greatest scientific and philosophical questions of our time. This compact and accessible book presents a modern view of human evolution. Written by a leading authority, it lucidly and engagingly explains not only the evolutionary process, but the technologies currently used to unravel the evolutionary past and emergence of Homo sapiens. By separating the history of palaeoanthropology from current interpretation of the human fossil record, it lays numerous misconceptions to rest, and demonstrates that human evolution has been far from the linear struggle from primitiveness to perfection that we've been led to believe. It also presents a coherent scenario for how Homo sapiens contrived to cross a formidable cognitive barrier to become an extraordinary and unprecedented thinking creature. Elegantly illustrated, Understanding Human Evolution is for anyone interested in the complex and tangled story of how we came to be.

Does eating more carbohydrates, or fats, cause one to put on more weight? Are ketone bodies toxins or vital products that keep us alive during starvation? Does the concept of 'fat-burning exercise' hold true? In this game-changing book, Keith Frayn, an international expert in human metabolism and nutrition, dispels common misconceptions about human metabolism, explaining in everyday language the important metabolic processes that underlie all aspects of our daily lives. Illustrated throughout with clear diagrams of metabolic processes, Frayn describes the communication systems that enable our different organs and tissues to cooperate, for instance in providing fuel to our muscles when we exercise, and in preserving our tissues during fasting. He explores the impressive adaptability of human metabolism and discusses the metabolic disorders that can arise when metabolism 'goes wrong'. For anyone sceptical of information about diet and lifestyle, this concise book guides the reader through what metabolism really involves.

Human life, and how we came to be, is one of the greatest scientific and philosophical questions of our time. This compact and accessible book presents a modern view of human evolution. Written by a leading authority, it lucidly and engagingly explains not only the evolutionary process, but the technologies currently used to unravel the evolutionary past and emergence of Homo sapiens. By separating the history of palaeoanthropology from current interpretation of the human fossil record, it lays numerous misconceptions to rest, and demonstrates that human evolution has been far from the linear struggle from primitiveness to perfection that we've been led to believe. It also presents a coherent scenario for how Homo sapiens contrived to cross a formidable cognitive barrier to become an extraordinary and unprecedented thinking creature. Elegantly illustrated, Understanding Human Evolution is for anyone interested in the complex and tangled story of how we came to be.

Does eating more carbohydrates, or fats, cause one to put on more weight? Are ketone bodies toxins or vital products that keep us alive during starvation? Does the concept of 'fat-burning exercise' hold true? In this game-changing book, Keith Frayn, an international expert in human metabolism and nutrition, dispels common misconceptions about human metabolism, explaining in everyday language the important metabolic processes that underlie all aspects of our daily lives. Illustrated throughout with clear diagrams of metabolic processes, Frayn describes the communication systems that enable our different organs and tissues to cooperate, for instance in providing fuel to our muscles when we exercise, and in preserving our tissues during fasting. He explores the impressive adaptability of human metabolism and discusses the metabolic disorders that can arise when metabolism 'goes wrong'. For anyone sceptical of information about diet and lifestyle, this concise book guides the reader through what metabolism really involves.

Challenge outdated views of evolution and embrace a clearer understanding of life's incredible diversity with this enlightening exploration of evolutionary trees. Far from being a linear ladder of progress, evolution is a vast, branching tree where all species-humans included-are evolutionary cousins, not ancestors or descendants. Every organism alive today shares the same 3.5 billion years of evolutionary history, uniquely adapted to its own environment. This book takes readers on a journey through the tree of life, beginning with humanity's closest relatives and expanding outward to the most distantly related organisms. By unravelling the misconceptions perpetuated by news articles and traditional depictions of evolution, it offers a fresh perspective on life's interconnectedness. With engaging insights and vivid illustrations, this book fosters a deeper appreciation for the remarkable complexity and diversity of life on Earth, making it an essential read for anyone curious about our evolutionary story.

The two most fascinating questions about extraterrestrial life are where it is found and what it is like. In particular, from our Earth-based vantage point, we are keen to know where the closest life to us is, and how similar it might be to life on our home planet. This book deals with both of these key issues. It considers possible homes for life, with a focus on Earth-like exoplanets. And it examines the possibility that life elsewhere might be similar to life here, due to the existence of parallel environments, which may result in Darwinian selection producing parallel trees of life between one planet and another. Understanding Life in the Universe provides an engaging and myth-busting overview for any reader interested in the existence and nature of extraterrestrial life, and the realistic possibility of discovering credible evidence for it in the near future.

The two most fascinating questions about extraterrestrial life are where it is found and what it is like. In particular, from our Earth-based vantage point, we are keen to know where the closest life to us is, and how similar it might be to life on our home planet. This book deals with both of these key issues. It considers possible homes for life, with a focus on Earth-like exoplanets. And it examines the possibility that life elsewhere might be similar to life here, due to the existence of parallel environments, which may result in Darwinian selection producing parallel trees of life between one planet and another. Understanding Life in the Universe provides an engaging and myth-busting overview for any reader interested in the existence and nature of extraterrestrial life, and the realistic possibility of discovering credible evidence for it in the near future.

Most people have some dissatisfaction or concern about body weight, fatness, or obesity, either personally or professionally. This book shows how the popular understanding of obesity is often at odds with scientific understandings, and how misunderstandings about people with obesity can further contribute to the problem. It describes, in an approachable way, interconnected debates about obesity in public policy, medicine and public health, and how media and social media engage people in everyday life in those debates. In chapters considering body fat and fatness, genetics, metabolism, food and eating, inequality, blame and stigma, and physical activity, this book brings separate domains of obesity research into the field of complexity. By doing so, it aids navigation through the minefield of misunderstandings about body weight, fatness, and obesity that exist today, after decades of mostly failed policies and interventions.

Our understanding of reproduction and reproductive processes is often biased towards the behaviour of organisms most familiar to us. As such, the amazing disparity of the phenomena of reproduction and sex is often overlooked. Understanding Reproduction addresses all the main facets of this large chapter of the life sciences, including discussions of asexual reproduction, parthenogenesis, sex determination, reproductive effort, and much more. The book features an abundance of examples from across the tree of life, including animals, plants, fungi, protists and bacteria. Written in an accessible and easy to digest style, overcoming the intimidating diversity of the technical terminology, this book will appeal to interested general readers, biologists, science educators, philosophers and medical doctors.

From photographs to micrographs, from the various types of graphs to fun, interactive visuals and games, there are many different forms in which science can be visualised. However, all of these forms of visualisation in the Life Sciences are susceptible to misunderstandings and misinformation. This accessible and concise book demonstrates the misconceptions surrounding the visuals used in popular life science communication. Richly illustrated in colour, this guide is packed with examples of commonly used visual types: photographs, micrographs, illustrations, graphs, interactive visuals, and infographics allowing visual creators to produce more effective visuals that aspire to being both attractive and informative for their target audience. It also encourages non-specialist readers to be more empowered and critical, to ask difficult questions, and to cultivate true engagement with science. This book is an invaluable resource for life scientists and science communicators, and anyone who creates visuals for public or non-specialist readers.

The relationship between science and religion is a topic that runs rife with misconceptions, misunderstandings and debates. Are science and religion always in conflict? Is Darwin's theory of evolution through natural selection atheistic? How does history shape current debates around science and religion? This book explores these questions in a neutral and balanced way, focusing on the Christianity-evolution relationship. It shows that two paradigms - the world as an organism and the world as a machine - have critically informed and guided the discussions. The author uses his deep understanding of the history and philosophy of science, particularly Darwinian evolutionary theory and its controversies through the past 150 years, to bring fresh ideas to the debate and to wider discussions such as environmental issues and hate. Understanding the Christianity-Evolution Relationship provides a lively and informative analysis and lays out multiple views so that readers can make their own judgements to increase their understanding.

Life is definitively purposive and creative. Organisms use genes in controlling their destiny. This book presents a paradigm shift in understanding living systems. The genome is not a code, blueprint or set of instructions. It is a tool orchestrated by the system. This book shows that gene-centrism misrepresents what genes are and how they are used by living systems. It demonstrates how organisms make choices, influencing their behaviour, their development and evolution, and act as agents of natural selection. It presents a novel approach to fundamental philosophical and cultural issues, such as free-will. Reading this book will make you see life in a new light, as a marvellous phenomenon, and in some sense a triumph of evolution. We are not in our genes, our genes are in us.

The legend of Charles Darwin has never been more alive or more potent, but by virtue of this, his legacy has become susceptible to myths and misunderstandings. Understanding Charles Darwin examines key questions such as what did Darwin's work change about the world? In what ways is 'Darwinism' reflective of Darwin's own views? What problems were left unsolved? In our elevation of Darwin to this iconic status, have we neglected to recognise the work of other scientists? The book also examines Darwin's struggle with his religious beliefs, considering his findings, and whether he was truly an atheist. In this engaging account, Peterson paints an intimate portrait of Darwin from his own words in private correspondence and journals. The result is the Darwin you never knew.

No two people are the same, and no two groups of people are the same. But what kinds of differences are there, and what do they mean? What does our DNA say about race, gender, equality, or ancestry? Drawing on the latest discoveries in anthropology and human genetics, Understanding Human Diversity looks at scientific realities and pseudoscientific myths about the patterns of diversity in our species, challenging common misconceptions about genetics, race, and evolution and their role in shaping human life today. By examining nine counterexamples drawn from popular scientific ideas, that is to say, examinations of what we are not, this book leads the reader to an appreciation of what we are. We are hybrids with often inseparable natural and cultural aspects, formed of natural and cultural histories, and evolved from remote ape and recent human ancestors. This book is a must for anyone curious about human genetics, human evolution, and human diversity.

Why do the debates about evolution persist, despite the plentiful evidence for it? Breaking down the notion that public resistance to evolution is strictly due to its perceived conflict with religion, this concise book shows that evolution is in fact a counterintuitive idea that is difficult to understand. Kostas Kampourakis, an experienced science educator, takes an insightful, interdisciplinary approach, providing an introduction to evolutionary theory written with clarity and thoughtful reasoning. Topics discussed include evolution in the public sphere, evolution and religion, the conceptual obstacles to understanding evolution, the development of Darwin's theory, the most important evolutionary concepts, as well as evolution and the nature of science. Understanding Evolution presents evolutionary theory with a lucidity and vision that readers will quickly appreciate, and is intended for anyone wanting an accessible and concise guide to evolution.

Why do the debates about evolution persist, despite the plentiful evidence for it? Breaking down the notion that public resistance to evolution is strictly due to its perceived conflict with religion, this concise book shows that evolution is in fact a counterintuitive idea that is difficult to understand. Kostas Kampourakis, an experienced science educator, takes an insightful, interdisciplinary approach, providing an introduction to evolutionary theory written with clarity and thoughtful reasoning. Topics discussed include evolution in the public sphere, evolution and religion, the conceptual obstacles to understanding evolution, the development of Darwin's theory, the most important evolutionary concepts, as well as evolution and the nature of science. Understanding Evolution presents evolutionary theory with a lucidity and vision that readers will quickly appreciate, and is intended for anyone wanting an accessible and concise guide to evolution.

Developmental biology is seemingly well understood, with development widely accepted as being a series of programmed changes through which an egg turns into an adult organism, or a seed matures into a plant. However, the picture is much more complex than that: is it all genetically controlled or does environment have an influence? Is the final adult stage the target of development and everything else just a build-up to that point? Are developmental strategies the same in plants as in animals? How do we consider development in single-celled organisms? In this concise, engaging volume, Alessandro Minelli, a leading developmental biologist, addresses these key questions. Using familiar examples and easy-to-follow arguments, he offers fresh alternatives to a number of preconceptions and stereotypes, awakening the reader to the disparity of developmental phenomena across all main branches of the tree of life.

What are genes? What do genes do? These questions are not simple and straightforward to answer; at the same time, simplistic answers are quite prevalent and are taken for granted. This book aims to explain the origin of the gene concept, its various meanings both within and outside science, as well as to debunk the intuitive view of the existence of 'genes for' characteristics and disease. Drawing on contemporary research in genetics and genomics, as well as on ideas from history of science, philosophy of science, psychology and science education, it explains what genes are and what they can and cannot do. By presenting complex concepts and research in a comprehensible and rigorous manner, it examines the potential impact of research in genetics and genomics and how important genes actually are for our lives. Understanding Genes is an accessible and engaging introduction to genes for any interested reader.

DNA ancestry companies generate revenues in the region of $1bn a year, and the company 23andMe is said to have sold 10 million DNA ancestry kits to date. Although evidently popular, the science behind how DNA ancestry tests work is mystifying and difficult for the general public to interpret and understand. In this accessible and engaging book, Sheldon Krimsky, a leading researcher, investigates the methods that different companies use for DNA ancestry testing. He also discusses what the tests are used for, from their application in criminal investigations to discovering missing relatives. With a lack of transparency from companies in sharing their data, absent validation of methods by independent scientists, and currently no agreed-upon standards of accuracy, this book also examines the ethical issues behind genetic genealogy testing, including concerns surrounding data privacy and security. It demystifies the art and science of DNA ancestry testing for the general reader.

Why do the best-known examples of evolutionary change involve the alteration of one kind of animal into another very similar one, like the evolution of a bigger beak in a bird? Wouldn't it be much more interesting to understand how beaks originated? Most people would agree, but until recently we didn't know much about such origins. That is now changing, with the growth of the interdisciplinary field evo-devo, which deals with the relationship between how embryos develop in the short term and how they (and the adults they grow into) evolve in the long term. One of the key questions is: can the origins of structures such as beaks, eyes, and shells be explained within a Darwinian framework? The answer seems to be yes, but only by expanding that framework. This book discusses the required expansion, and the current state of play regarding our understanding of evolutionary and developmental origins.

Since the identification of the first cases of the coronavirus in December 2019 in Wuhan, China, there has been a significant amount of confusion regarding the origin and spread of the so-called 'coronavirus', officially named SARS-CoV-2, and the cause of the disease COVID-19. Conflicting messages from the media and officials across different countries and organizations, the abundance of disparate sources of information, unfounded conspiracy theories on the origins of the newly emerging virus and the inconsistent public health measures across different countries, have all served to increase the level of anxiety in the population. Where did the virus come from? How is it transmitted? How does it cause disease? Is it like flu? What is a pandemic? What can we do to stop its spread? Written by a leading expert, this concise and accessible introduction provides answers to the most common questions surrounding coronavirus for a general audience.

What are genes? What do genes do? These questions are not simple and straightforward to answer; at the same time, simplistic answers are quite prevalent and are taken for granted. This book aims to explain the origin of the gene concept, its various meanings both within and outside science, as well as to debunk the intuitive view of the existence of 'genes for' characteristics and disease. Drawing on contemporary research in genetics and genomics, as well as on ideas from history of science, philosophy of science, psychology and science education, it explains what genes are and what they can and cannot do. By presenting complex concepts and research in a comprehensible and rigorous manner, it examines the potential impact of research in genetics and genomics and how important genes actually are for our lives. Understanding Genes is an accessible and engaging introduction to genes for any interested reader.

Developmental biology is seemingly well understood, with development widely accepted as being a series of programmed changes through which an egg turns into an adult organism, or a seed matures into a plant. However, the picture is much more complex than that: is it all genetically controlled or does environment have an influence? Is the final adult stage the target of development and everything else just a build-up to that point? Are developmental strategies the same in plants as in animals? How do we consider development in single-celled organisms? In this concise, engaging volume, Alessandro Minelli, a leading developmental biologist, addresses these key questions. Using familiar examples and easy-to-follow arguments, he offers fresh alternatives to a number of preconceptions and stereotypes, awakening the reader to the disparity of developmental phenomena across all main branches of the tree of life.