Methods in Pharmacology and Toxicology – serie
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103 produkter
Cancer-Targeted Drug Delivery
Av Ülo Langel
Inbunden, 2025
2816 kr
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This detailed volume explores the frontiers of tumor targeting approaches in the field of tumor-targeted drug delivery and cancer therapy. Several topics involve the improvement of cancer detection and treatment using nanotechnologies, where the main challenge to transition from the laboratory to …
Methods in Biological Oxidative Stress
Av Kenneth Hensley, Robert A. Floyd
Inbunden, 2003
1098 kr
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Oxidative damage appears to play a central role in the development of a wide range of tissue pathology, including neurodegenerative disease, drug side-effects, xenobiotic toxicity, carcinogenesis, and the aging process, to name just a few. Because of the centrality of oxidative processes to normal …
Ion Channel Localization
Av Anatoli Lopatin, Colin G. Nichols
Inbunden, 2001
1693 kr
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Since the pioneering discoveries of Hodgkin, Huxley, and Katz, it has been clear that specific ion conductance pathways underlie electrical act- ity. Over the ensuing 50 years, there has been ever increasing, and occasi- ally explosive, changes in the scope of efforts to understand ion channel …
Apoptosis Methods in Pharmacology and Toxicology
Approaches to Measurement and Quantification
Inbunden, 2002
1131 kr
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Dr. Myrtle A. Davis has assembled a panel of cutting-edge scientists to describe their best methods for detecting, illuminating, and quantifying apoptotic mechanisms in a way that is useful for the design of toxicology and pharmacology studies. These state-of-the-art techniques include flow …
Ecotoxicological QSARs
Av Kunal Roy
Inbunden, 2020
2254 kr
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This volume focuses on computational modeling of the ecotoxicity of chemicals and presents applications of quantitative structure–activity relationship models (QSARs) in the predictive toxicology field in a regulatory context. The extensive book covers a variety of protocols for descriptor …
Ecotoxicological QSARs
Av Kunal Roy
Häftad, 2021
2030 kr
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This volume focuses on computational modeling of the ecotoxicity of chemicals and presents applications of quantitative structure–activity relationship models (QSARs) in the predictive toxicology field in a regulatory context. The extensive book covers a variety of protocols for descriptor …
Immuno-Oncology
Cellular and Translational Approaches
Av Seng-Lai Tan
Inbunden, 2020
1917 kr
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This book serves as a guide for identifying and applying commonly used cell-based translational assays as well as for assessing the therapeutic potential of new immuno-oncology therapeutics and advancing their mechanism of action. The detailed chapters within will provide readers with a baseline …
Immuno-Oncology
Cellular and Translational Approaches
Av Seng-Lai Tan
Häftad, 2021
1355 kr
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This book serves as a guide for identifying and applying commonly used cell-based translational assays as well as for assessing the therapeutic potential of new immuno-oncology therapeutics and advancing their mechanism of action. The detailed chapters within will provide readers with a baseline …
Quantitative Analysis of Cellular Drug Transport, Disposition, and Delivery
Av Gus R. Rosania, Greg M. Thurber
Inbunden, 2021
1917 kr
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This thorough book explores some of the most important methods and concepts affecting the quantitative analysis of the transport, targeting, and disposition of chemicals within cells, which in turn impact the macroscopic pharmacokinetics of chemical agents in the whole organism. The first half of …
Quantitative Analysis of Cellular Drug Transport, Disposition, and Delivery
Av Gus R. Rosania, Greg M. Thurber
Häftad, 2021
1355 kr
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This thorough book explores some of the most important methods and concepts affecting the quantitative analysis of the transport, targeting, and disposition of chemicals within cells, which in turn impact the macroscopic pharmacokinetics of chemical agents in the whole organism. The first half of …
In Silico Modeling of Drugs Against Coronaviruses
Computational Tools and Protocols
Av Kunal Roy
Inbunden, 2021
3715 kr
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This essential volume explores a variety of tools and protocols of structure-based (homology modeling, molecular docking, molecular dynamics, protein-protein interaction network) and ligand-based (pharmacophore mapping, quantitative structure-activity relationships or QSARs) drug design for ranking …
In Silico Modeling of Drugs Against Coronaviruses
Computational Tools and Protocols
Av Kunal Roy
Häftad, 2021
2693 kr
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This essential volume explores a variety of tools and protocols of structure-based (homology modeling, molecular docking, molecular dynamics, protein-protein interaction network) and ligand-based (pharmacophore mapping, quantitative structure-activity relationships or QSARs) drug design for ranking …
Cytochrome P450
In Vitro Methods and Protocols
Av Zhengyin Yan, Gary W. Caldwell
Inbunden, 2021
1917 kr
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This collection explores detailed experimental protocols necessary for setting up a variety of in vitro cytochrome P450 (CYP) assays that are vital in selecting drug candidates in a drug discovery pipeline. Major factors affecting drug metabolism include CYP expression levels, kinetic parameters …
Cytochrome P450
In Vitro Methods and Protocols
Av Zhengyin Yan, Gary W. Caldwell
Häftad, 2022
1355 kr
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This collection explores detailed experimental protocols necessary for setting up a variety of in vitro cytochrome P450 (CYP) assays that are vital in selecting drug candidates in a drug discovery pipeline. Major factors affecting drug metabolism include CYP expression levels, kinetic parameters …
Green Chemistry in Drug Discovery
From Academia to Industry
Inbunden, 2021
2479 kr
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This detailed book highlights several emerging areas in the implementation of green chemistry in medicinal chemistry drug discovery with a specific focus on their application to the expeditious discovery of new biologically active entities. Divided into three sections, the collection explores …
Pesticide Toxicology
Av Eugenia Gallardo, Mário Barroso
Inbunden, 2021
1917 kr
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This detailed volume explores practical procedures on the identification and quantification of pesticides in a variety of samples. Chapters guide the reader through methods and protocols for the extraction of pesticides from biological and non-biological samples, pitfalls in dosing techniques and …
Pesticide Toxicology
Av Eugenia Gallardo, Mário Barroso
Häftad, 2022
1355 kr
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This detailed volume explores practical procedures on the identification and quantification of pesticides in a variety of samples. Chapters guide the reader through methods and protocols for the extraction of pesticides from biological and non-biological samples, pitfalls in dosing techniques and …
Green Chemistry in Drug Discovery
From Academia to Industry
Häftad, 2021
1805 kr
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This detailed book highlights several emerging areas in the implementation of green chemistry in medicinal chemistry drug discovery with a specific focus on their application to the expeditious discovery of new biologically active entities. Divided into three sections, the collection explores …
In Situ Bioavailability and Toxicity of Organic Chemicals in Aquatic Systems
Av Thomas-Benjamin Seiler, Markus Brinkmann
Inbunden, 2022
1917 kr
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This detailed volume examines the complex study of the assessment of in situ bioavailability and toxicity of organic chemicals in aquatic systems with a toolbox of reliable techniques. Beginning with a section on approaches for chemical analytical and bioanalytical techniques in bioavailability …
In Situ Bioavailability and Toxicity of Organic Chemicals in Aquatic Systems
Av Thomas-Benjamin Seiler, Markus Brinkmann
Häftad, 2023
1355 kr
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This detailed volume examines the complex study of the assessment of in situ bioavailability and toxicity of organic chemicals in aquatic systems with a toolbox of reliable techniques. Beginning with a section on approaches for chemical analytical and bioanalytical techniques in bioavailability …
Methods for Novel Psychoactive Substance Analysis
Av Marta Concheiro, Karl B. Scheidweiler
Inbunden, 2022
1693 kr
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This collection provides detailed information on current advances in analytical methods and strategies employed for monitoring and discovering a wide range of novel psychoactive substances (NPS) in clinical and forensic laboratories. The main classes of NPS in terms of prevalence include synthetic …
Methods for Novel Psychoactive Substance Analysis
Av Marta Concheiro, Karl B. Scheidweiler
Häftad, 2023
1243 kr
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This collection provides detailed information on current advances in analytical methods and strategies employed for monitoring and discovering a wide range of novel psychoactive substances (NPS) in clinical and forensic laboratories. The main classes of NPS in terms of prevalence include synthetic …
Cancer-Targeted Drug Delivery
Av Ülo Langel
Häftad, 2026
2030 kr
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This detailed volume explores the frontiers of tumor targeting approaches in the field of tumor-targeted drug delivery and cancer therapy. Several topics involve the improvement of cancer detection and treatment using nanotechnologies, where the main challenge to transition from the laboratory to …
Next-Generation Drug Delivery Systems
Av Abhishek Pathak, Satya Pal Singh
Inbunden, 2025
3036 kr
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This book provides a detailed yet accessible guide to emerging trends in drug delivery systems. Topics encompass a wide range of delivery mechanisms, including nanotechnology-based carriers, controlled-release formulations, targeted delivery systems, and biologics, with a focus on their role in …
Next-Generation Drug Delivery Systems
Av Abhishek Pathak, Satya Pal Singh
Häftad, 2026
1580 kr
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This book provides a detailed yet accessible guide to emerging trends in drug delivery systems. Topics encompass a wide range of delivery mechanisms, including nanotechnology-based carriers, controlled-release formulations, targeted delivery systems, and biologics, with a focus on their role in …
Cancer Prevention
Dietary Factors and Pharmacology
Inbunden, 2013
1688 kr
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Focused on the discovery of precise molecular targets for the development of the cancer preventive agents, Cancer Prevention: Dietary Factors and Pharmacology provides researchers and non-researchers with practical methodologies for developing and validating small molecule and phytochemical-derived …
Cardiac Drug Development Guide
Häftad, 2013
1128 kr
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Cardiac Drug Development Guide outlines, in detail, the therapeutics of cardiac medicine currently at the cutting edge of scientific research and development around the world. This volume integrates basic and clinical cardiac pharmacology by c- bining, for the first time, both classical and …
In Vitro Toxicology Systems
Av Anna Bal-Price, Paul Jennings
Inbunden, 2014
2473 kr
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In Vitro Toxicology Systems brings together important issues and considerations needed in order to develop a workable, reliable, integrated testing strategy for the replacement of animals in toxicity testing regimes. This thorough volume includes sections on in vitro models for systemic organ …
Genotoxicity and DNA Repair
A Practical Approach
Av L. María Sierra, Isabel Gaivão
Inbunden, 2014
1688 kr
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Genotoxicity and DNA Repair: A Practical Approach provides a key reference for determining how to analyze the genotoxic activity of molecules or materials and, at the same time, serves as a useful tool for researchers in the Environmental Mutagenesis and DNA Repair fields. Focused on genotoxicity …
Label-Free Biosensor Methods in Drug Discovery
Av Ye Fang
Inbunden, 2015
1128 kr
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This volume explores label-free biosensors, advantageous in part because this technology bypasses the need of labels, reporters, and cell engineering, all of which are common to labeled techniques but may introduce artifacts in assay results. Addressing several fundamental and practical aspects as …
