Progress in Biochemistry and Biotechnology – serie

Bacterial Laccases: Engineering, Immobilization, Heterologous Production, and Industrial Applications provides a list of approaches that upgrades bacterial laccases to industrially relevant enzymes. Providing protocols for enzyme production and downstream processing, and including up-to-date information on bacterial laccases, as well as techniques that can be explored to enhance properties and production levels, this book clarifies research gaps and explains how they can be dealt with. Written for research scholars working on enzymes, this is a valuable tool for industries and policymakers. Leads to a better understanding of traditional and novel methodologies for enhancing production and properties of bacterial laccases Serves as a useful guide for researchers, industrialists and students Includes chapters written by experts known for their contributions in respective areas Describes the latest advances made in the field of bacterial laccases, including strategies that could be undertaken to improve their utility at an industrial level Provides a comprehensive, up-to-date review of bacterial laccases and their important applications

Advances in Nano and Biochemistry: Environmental and Biomedical Applications gives insights into this advanced interdisciplinary science that encompasses the principles of physics and physical chemistry for the investigation of various processes and problems in biological systems. The book is a concise culmination of biophysical chemistry knowledge acquired through core concepts and advanced technologies for addressing emerging challenges in environmental and biomedical applications. Sections cover early diagnostic techniques and accurate treatment strategies using bioinspired, sustainable technologies, including nanomaterials, nanoenzymes, biopolymers, electrochemical biomolecule sensors, biocompatible magnetic nanomaterials, quantum dots and hybrid structures, and DNA nanotechnology.

Other sections discuss advanced technologies for sensing and remedying environmental pollutants, including but not limited to, photocatalytic oxidations, gum polysaccharides based nanostructured materials, bio-inspired and biocompatible nanomaterials, hydrogel nanocomposites, and contemporary enzymes and nanozymes based?technologies. Ultimately, the state-of-the-art chapters in this book will empower researchers to combine two complementary elements - chemical analysis use and biomedical applications.

Provides the fundamental concepts of biophysical chemistry and emerging technologies to solve environmental and biomedical problems Describes the latest breakthrough research in biophysical chemistry and its applications to better understand biological systems Supports development of the latest disease diagnostic and treatment technologies Includes advances in physical chemistry and biology for the monitoring and remediation of environmental pollutants

Microbial processes are involved in food, chemical, pharmaceutical, cosmetics, energy, and new-material industries. Over the past 2 decades, new or more efficient industrial processes involving microorganisms have been launched, yielding purer, less expensive products or substances not available using classical chemical methods. Microbial Bioprocesses aims to give an overview of established and successful processes and discusses the trends and perspectives in industrial microbiology which, along with tremendous progress in genetic and metabolic engineering in recent years, are once again becoming an area of innovation and emerging technologies. Microbial Bioprocesses covers the unique areas like microbial volatiles (MVOCs), microbial bioinoculant development, bacterial nanocelluloses production, and processes for remediation by fungi and actinobacteria.

Provides an innovative description of emerging bioprocesses for biotechnological gains Provides a broad cross section of microbial bioprocess that covers several sustainability applications Gives general insights about how microorganisms can be utilized in production of various chemicals

Fundamentals of Recombinant Protein Production, Purification and Characterization is organized into nine chapters in a logical fashion that cover an introduction to recombinant proteins and expression in different host expression systems, extraction, purification and analysis of proteins. This important reference features protocols, along with the advantages and disadvantage of each expression hosts and characterization technique (presented in tabular format) and offers detailed coverage of all aspects of protein production and processing (upstream and downstream processing) in one place. Finally, the book ends with different characterization techniques. Production of recombinant proteins for biotechnological and therapeutic applications at a large scale is an essential need of mankind. With the huge application potential of therapeutic and industrial proteins, there has been increasing demand for effective and efficient bioprocessing strategies. Recent progress around recombinant DNA technologies and bioprocessing strategies has paved the way for efficient production of recombinant proteins. Important factors such as insolubility and cost of production need to be considered for large scale production of these recombinant proteins.

Includes step-by-step reproducible protocols while also providing updated information on the rationale and latest developments in expression systemsCan also be used as a handbook for protein expression and purification as expression systems and chromatographic methods are explained in detailConsists of notes on troubleshooting from the eminent researchers in the fieldProvides comprehensive information on protein production, purification and characterization in a single volumeDescribes different purification methods for comparatively difficult to obtain proteinsBrings the topics of recombinant protein expression, purification and characterization together, thereby making it the first resource on how to solve problems with respect to upstream and downstream processing of heterologous proteins

Microbial Xylanolytic Enzymes describes the enzyme structure and its interaction with plant cell walls, the properties and production of different enzymes and their applications, and the knowledge gathered on the hydrolysis mechanism of hemicellulose. The knowledge gathered about the hydrolysis mechanism of the hemicelluloses, especially xylans, has greatly promoted the rapid application of these enzymes in new areas. In recent years, there has been a spurt of interest in xylan degrading enzymes due to their applications in several industrial processes, including paper and pulp industries, food and feed industries, biofuel industry, textile industry, chemical and pharmaceutical industry, brewing industry, and more.

Xylan is the principal type of hemicellulose. An enzymatic complex is responsible for the hydrolysis of xylan, but the main enzymes involved are enzymes produced by fungi, bacteria, yeast, algae, protozoans, and more.

Gives up-to-date authoritative information and cites pertinent research on the synergistic action of xylanolytic enzymes Includes studies on xylanase regulation and synergistic action between multiple forms of xylanase Covers, in great depth, all aspects of Xylanolytic enzymes Includes detailed descriptions on Xylanolytic enzymes as a supplement in animal feed, for the manufacture of bread, food and drinks, textile industry, pulp and paper industry, biofuel industry and production of pharmaceuticals and important chemicals and waste management, etc. Challenges future trends in the commercial production and application of xylanases

Cyanobacteria: Metabolisms to Molecules covers diversity, fundamental metabolisms, crucial metabolities, their synthesis, and bioinformatics topics surrounding cyanobacteria, an organism regarded as the most important organism to sustain life on the planet during ancient times. Cyanobacteria are among the first pioneering communities on various harsh habitat, hydrarch or xerarch, which finally facilitate the emergence of vast communities including higher plants. Being the progenitor of chloroplast, the cyanobacterial metabolisms has always fascinated microbiologists. Additionally, the ability of these prokaryotes to produce valuable and prolific sources of natural products signified their role in an array of industrial sectors. Therefore, in this book, the book's authors accumulate the current knowledge of cyanobacterial metabolisms and molecules as a valuable asset for students, researchers, and biotechnologists.

Casts light on cyanobacterial assistance and their potential role in sustainable developmentsProvides significant insights into the fundamentals of cyanobacterial metabolism as well as lesser known topicsDetermines the role of cyanobacteria in public health

Industrial Applications of Biosurfactants and Microorganisms Green Technology Avenues from Lab to Commercialization covers a variety of current biosurfactant research advancements and progresses, providing insights into the most recent academic advances, major applications, and implementation studies from across the world. The book focuses entirely within the scope of biochemistry and biotechnology research and demonstrates the application of biosurfactants in cell mobility, cell communication, nutrient acquisition, and plant and animal disease. Biosurfactants have antibacterial, antifungal, and antiviral properties, as well as adhesive properties and are used in vaccinations, gene therapy, and the enhancement of microbial biocontrol systems. This book is designed for a broad audience working in the fields of biochemistry, surface science, colloid and interface science, and is an invaluable reference for university libraries and industrial institutions, government and independent institutes, individual research groups, and scientists working in the field of surface science systems.

Provides biosurfactants production and applications in modern industrial platformsEvaluates biosurfactants as prime options for sustainable and transformation opportunitiesServes as a valuable reference for scientists and engineers who are searching for modern design for biosurfactantsFocuses on the most advanced biosurfactants, industry-oriented applications including current challenges during manufacturing

New Horizons in Natural Compound Research provides the latest updates in natural compound research (plant, microbes, algae, fungi) and their novel applications in health, agriculture and environment. The book gives recent advances in the extraction of natural compounds, cutting-edge approaches for natural compound purifications, and emerging trends in natural compound screening and identification. In addition, it provides a detailed explanation of the databases and libraries of natural compounds, as well as their significance. Sections focus on research and multidisciplinary practical techniques of natural product research, encouraging young scientists to pursue unique research while also generating strong research ideas.

From a future perspective, this book acts as a guide to identify potential areas and new research opportunities in the field of natural products and their service towards human beings, animals and the environment.

Provides a one-stop solution for concepts, cutting-edge techniques, methods, and novel applications of natural products in health and the environment Focuses on current gaps in natural product research, as well as methodologies and techniques to assist researchers in resolving existing challenges and speeding up the pace of drug discovery from natural sources Highlights new avenues of natural product research Contains contributions from well-experienced researchers from academia, research institutes and top-notch young scientists from industry

Myconanotechnology and Application of Nanoparticles in Biology: Fundamental Concepts, Mechanism and Industrial Applications focuses on the emergence of myconanotechnology as a new science for the synthesis of nanoparticles using fungi and considering future applications and challenges. The book demonstrates why mycology should be regarded as a megascience: A subject requiring international collaboration to overcome barriers that need to be confronted in the interests of global security and human well-being. This reference provides a good source of knowledge and guidelines for advanced graduate students and will be of significant interest to scientists working on the basic issues surrounding applications of myconanotechnology.Highlights established specific applications of myconanotechnology in various industrial sectors and discusses future research directionsProvides academic and industry a high-tech start-up that will revolutionize modern industrial practicesOffers a comprehensive coverage on myconanotechnology including real-time case studiesFocuses on the emergence of myconanotechnology as a new science for the synthesis of nanoparticles by using fungiCarries out an in-depth and step-by-step description of knowledge on myco-nanotechnology, current research trends, opportunities and their involvement in modern society

Bioreactor Design Concepts for Viral Vaccine Production covers a range of interdisciplinary chapters from the engineering perspective of bioreactor design to the biotechnological perspectives of vector design for vaccine development. The book covers bioreactor concepts such as static systems, single-use systems, stirred tanks, perfusion, wave and packed-beds. It reviews options for efficient and economical production of human vaccines and discusses basic factors relevant for viral antigen production in mammalian cells, avian cells, and insect cells. This book will be a great resource for those interested in implemented novel bioreactor design or experimental schemes towards intensified or/and enhanced vaccine production. Covers the fundamentals of bioreactor designs Provides strategies for designing a successful vector-based vaccine Discusses the applications of biological kinetics, thermodynamics and basic substrate requirements for viral vaccine production

Biotechnology of Emerging Microbes: Prospects for Agriculture and Environment provides the latest developments of leading biotechnologists and bioengineers. The book covers various aspects of microbes mediated rhizosphere, biosphere, environmental, and ecosystem biotechnology, and focuses on the restoration and management of the rhizosphere, the biosphere, and the ecosystem with microbes for a sustainable future. It is designed to address various technical and application details of microorganisms and their products in biotechnology and bioengineering approaches. Users will find up-to-date knowledge that is beneficial to beginners, researchers, students, scientists, engineers, and industry stakeholders who can support the management of ecosystems through the use of microbes.

Planet Earth is undergoing an accelerated process of change associated with a wide range of anthropogenic phenomena. The future of these changes is uncertain, but there is general agreement that this negative development might be detrimental to our own survival. Although different environmental engineering strategies have been developed, none of them seem to address carbon dioxide accumulation, biosphere, and ecosystem safety. The rapidly increasing potential for the development of living systems through the biotechnology and bioengineering of microbes is a sustainable alternative to address safety issues.

Addresses various technical and application details of microorganisms and their products for biotechnology and bioengineering approaches Brings together the ideas and latest developments of leading biotechnologists and bioengineers Covers various aspects of microbes mediated rhizosphere, biosphere, environmental, and ecosystem biotechnology

Carbon-Based Nanomaterials in Biosystems: Biophysical interface at Lower Dimensions provides a thoroughly comprehensive overview of all major aspects of carbon-based nanomaterials, their biophysical response, and biotechnological applications. The book articulates the underlying physics, chemistry, and the basic phenomenon of the broad-range carbon-based nanomaterials (CNMs) with biological systems, particularly the interface analysis. Organized in six sections, it discusses state-of art technological interventions of carbon-based nanomaterials and their application in biomedical sectors in healthcare, food sciences, and technology. The book also highlights the carrying capacity of different CNMs in payload efficiency mechanisms in various biomedical fields. The theranostic efficiency and the safety of various forms of CNMs is assessed. This book will be a helpful resource to those specializing in the areas of nanomedicine, bionanomaterials, and nanotechnology applications.

Covers major breakthroughs in carbon nanomaterials (CNMs)Distinguishes between the advantages and disadvantages of carbon-based and non-carbon-based nanomaterialsDiscusses the significance of different forms of carbon nanomaterials and their unique physico-chemical and electrochemical properties at the lower dimensionExamines the appropriate methodologies for tackling safety and health-related matters while using carbon-based nanomaterialsDiscusses recent developments of various forms of carbon-based nanomaterials such as graphene, carbon nanotubes, fullerenes, and carbon nano-onions

Bacterial Physiology and Biochemistry provides the most current, authoritative, and relevant presentation of bacterial physiology and biochemistry on subject, chemical composition and functional bacterial cell structure, nutrition and growth, the process of cell differentiation, metabolism and the influence of environmental factors. The book helps the reader learn and obtain modern knowledges on bacterial physiology and biochemistry, including chemical composition and functional cell structures, bacterial nutrition and growth, and the processes of cell differentiation, bacterial metabolism and microbial growth in nature, and the effect of environmental factors on bacterial cells.

This book is an educational resource designed for use in advanced bachelor's and master's courses in biology, including microbiology, biochemistry and molecular biology. It contains curriculum taught to biology students specializing in microbiology.

Contains modern original color illustrations of biochemical and metabolic processes Provides condensed knowledge on microbiology, microbial kinetics and microbial physiology Includes easy-to-find information on key metabolic pathways in aerobic and anaerobic microorganisms

**2026 PROSE Award Category Winner in Biomedicine and Neuroscience**The role of environmentally triggered genetic and epigenetic changes in microbial adaptation and evolution is still not broadly appreciated. Brave Genomes: Microbial Genome Plasticity in the Face of Environmental Challenge narrates how microorganisms cope with environmental changes including unanticipated ones. Although it does comprise eukaryotes, it focuses on bacteria and - whenever possible - on archaea.Among the environmentally sensitive sources of genome plasticity, the book treats tandem repeats, mutagenic break repair, transcription-associated mutagenesis and transposable elements. Additionally, it deals with epigenetic mechanisms such as DNA methylation and regulatory RNA-based systems. These not only regulate the activity of mobile DNA, they can also synergize with it. In closing, symbiosis and genetic noise are also discussed as possible sources of phenotypic plasticity.Brave Genomes emphasizes the role of the environment in generating genotypic and phenotypic diversity. This emerges, in turn, as the most efficient response to challenging conditions.Compares environmentally sensitive genetic systems across the three kingdoms of life (bacteria, archaea, eukaryotes)Compares environmentally sensitive epigenetic systems across the three kingdoms of lifeBrings together insights of illustrious scientists including Josep Casad�sus, Remus Dame, Cedric Feschotte, William Martin, Eva Jablonka, Eugen KooninMicrobial symbioses and genetic noise are also treated as potential sources of phenotypic plasticity and adaptability together with more traditional sourcesFamiliarizes biologists with this discipline by using a colloquial style

Nano-Enzyme Incorporated Particles: Fundamental Concepts, Synthesis and Applications focuses on integrative approaches of the enzyme nanoparticle synthesis and its applications on biomedicine, biosensors and biocatalysis. The book discusses the vital activities of nanozymes in enzyme mimicking processes and covers the latest methods and procedures involved. Divided into five sections, this book covers the production and characterization of enzyme nanoparticles, the activities, properties, and applications of enzyme nanoparticles, the development of nanocatalysts as analytical tools, and the degradation of nanoparticles. It covers potential investigations regarding aspects of production, characterization, and applications of enzyme incorporated nanoparticles.Focuses on integrative approaches of the enzyme nanoparticle synthesis and its applications on biomedicine, biosensors, and biocatalysisEncloses the potential challenges and developments of enzyme incorporated nanoparticlesDiscusses the vital activities of nanozymes in enzyme mimicking processes and prudent bio-catalytic efficiencyCovers the latest methods and procedures involved in enzyme-incorporated nanomaterials

Developments and Applications of Enzymes from Thermophilic Microorganisms extensively presents the industrial application of thermophilic/hyperthermophilic enzymes. The book brings thorough and in-depth coverage on the role of these enzymes in a broad range of industries, focusing on present scenarios of these enzymes in biofuel industries, including recent advancements. The use of thermophilic enzymes in 2G biorefineries may enable the whole production process to take place at high temperatures, allowing increased reaction rate and reduced costs. Researchers in biochemistry, microbiology, microbial technology, biotechnology, molecular biology and bioresource technology will benefit from the new insights given on potential applications of hyperthermophiles.

Hyperthermophilic enzymes, many of which survive at temperatures at or above 100C, contain novel macromolecules and metabolic systems which represent a vast resource for fundamental molecular and physiological studies, and for potential exploitation in biotechnology.

Covers the role of thermophilic/hyperthermophilic enzymes in a broad range of industries Explains the Importance of thermophilic/hyperthermophilic enzymes in biorefineries using examples of lignocellulose and starch conversions to desired products Discusses the existing and potential applications of thermophiles/hyperthermophilic enzymes

Enzyme Biotechnology for Environmental Sustainability discusses recent applications of enzyme biotechnology in various industrial sectors and state-of-the-art information on novel microbial enzyme technologies for a sustainable environment.The book describes in detail the latest developments and modern methods in microbial enzyme biotechnology for wider application in bioremediation, cleaner technology for industries and waste management, green chemistry and pharmaceutical biotechnology, sustainable textiles, food production and biodegradation, and other industries. The chapters cover topics such as genetic engineering, protein engineering, nanotechnological advances of microbial enzymes, computational tools for engineering enzymes, and health risk assessment of enzymes in different sectors. With contributors from an array of experts in the field, Enzyme Biotechnology for Environmental Sustainability is an informative reference for researchers, biotechnologists, microbiologists, environmental scientists, graduate and post-graduate students working in the area of enzyme technology and their biomedical, environmental, and industrial applications.

Includes new-methods and up-to-date information on modern methods with respect to its application in pharmaceuticals, textiles, food fermentation, and many other related fieldsProvides in-depth information about the recent applications of enzyme biotechnology in different industrial sectorsFocuses on the rapid developments and biotechnological advances in microbial enzymology to enhance industrial and environmental sustainability

Peroxidases: Biochemical Properties, Roles, Mechanism and Applications delves into the world of peroxidases, enzymes crucial in various biochemical and industrial processes. This comprehensive guide starts with an exploration of the origins and biochemical properties of peroxidases from sources such as animals, plants, and microbes. It explains their classifications, mechanisms of action, and the molecular evolution of different peroxidase families. Additionally, the book discusses the enhancement of peroxidase activities and their role in biotechnology. The second part of the book highlights the applications of peroxidase in organic synthesis, the pulp-paper industry, diagnostic kits, and biosensors.Finally, the book examines advanced healthcare applications, including targeted cancer therapies and enzyme immunoassays. This detailed resource is aimed at researchers, practitioners, and students in biochemistry, biotechnology, and related scientific fields.Provides comprehensive coverage of the biochemical properties, roles, and mechanisms of peroxidases, offering a deep understanding of these essential enzymesShowcases diverse applications of peroxidases in biotechnology, medicine, and industry, highlighting their utility in bioremediation, diagnostics, biofuel production, and moreExamines advanced techniques to improve peroxidase activities and stability, facilitating practical insights for enhancing enzyme performance in various applicationsExplores the molecular evolution and classification of peroxidase families and superfamilies, providing a detailed context for their functional diversityIncludes future prospects and emerging strategies in peroxidase research, guiding readers towards new research directions and innovative applications in the field

Combinatorial Biotechnology: Methods for Synthesis of Peptide, Oligonucleotide and Oligosaccharide Libraries and Applications covers methods used for synthesizing peptide, oligonucleotide, and oligosaccharide libraries. It presents the concepts of combinatorial biotechnology, detailing both solid phase and solution phase synthesis techniques, including modern biological methods such as in vitro and in vivo display libraries. Key topics include solid phase synthesis, parallel peptide synthesis, encoding technologies, deconvolution methods, and chemical and biological ligations. With chapters covering the chemical and biological synthesis of recombinant peptides and proteins, as well as the genetic reprogramming of the genetic code, this book offers a rich source of practical guidance.The inclusion of advanced methods and illustrative examples makes it a unique and essential reference in the field. This book is an essential resource for undergraduate and postgraduate students in biochemical engineering, biotechnology, and biosciences, as well as industry professionals in R&D divisions. It equips readers with the latest techniques and applications in combinatorial biotechnology, addressing current challenges and advancing their research and development efforts.Provides comprehensive methods for the synthesis of peptide, oligonucleotide, and oligosaccharide librariesCovers both solid phase and solution phase synthesis techniques, including modern biological methodsExamines encoding technologies and deconvolution methods that are essential for combinatorial biotechnologyOffers valuable insights for researchers in protein engineering, molecular biology, and drug discoveryServes as a unique reference with no existing textbooks or reference books on this specialized subject

Enzyme Technology for Environmental Sustainability, Waste to Wealth, and Circular Economy offers a comprehensive look at how enzyme technology can drive environmental progress within the framework of biochemistry. Beginning with foundational concepts, the book introduces readers to the science behind enzymes and their practical applications. Each chapter builds upon these basics, illustrating how enzymes catalyze vital processes that contribute to sustainability and the transformation of waste into valuable resources. Through focused case studies and clear explanations, the book demonstrates the potential of enzyme-driven solutions to address urgent environmental challenges and promote a circular economy.Beyond its central focus, the book stands out by delivering pragmatic examples that remain within biochemical boundaries, avoiding broader discussions in public health or environmental science. It is designed as a valuable reference for biochemists, researchers, and industry professionals, emphasizing collaboration and innovation rooted in biochemical expertise. Readers will gain an enriched understanding of enzyme technology’s role in sustainable industrial practices and the future of environmentally responsible solutions.Presents thorough case studies and success stories from diverse industries, offering practical insights into enzyme technologyHighlights the necessity of interdisciplinary approaches in enzyme technology, providing models and perspectives that encourage cooperation across biotechnology, chemistry, engineering, and environmental scienceDelivers a forward-looking analysis of emerging trends and innovations in applied enzyme technology, equipping readers with knowledge on future challenges and opportunities in the field

Extracellular Vesicle-Based Biovectors for Diagnostic and Biomedical Applications provides comprehensive coverage on not only the biosynthesis, isolation, purification, and functionalization of extracellular vesicles for therapeutic and diagnostic applications, but also current trends in functionalized extracellular vesicles for biomedical research and commercial-scale opportunities. Sections focus on the fundamental aspects of extracellular vesicles, covering their origin, classification, biosynthesis, isolation techniques, purification challenges, and functionalization for biomedical applications, while also delving into the therapeutic applications of extracellular vesicles and their role in treating diseases.Content also address biocompatibility, safety, translation challenges, biocompatibility, and translation challenges. Final sections explore the diagnostic potential of extracellular vesicles in biomedical research, highlighting their role as diagnostic biomarkers in various diseases. Emerging technologies and future directions in extracellular vesicle research round out the content, making it a valuable reference for researchers and clinicians seeking an in-depth understanding of extracellular vesicles and their potential biomedical applications.Discusses fundamentals and explains the biosynthesis, isolation, purification, and functionalization techniques of extracellular vesiclesDelves into recent advances of extracellular vesicles-based biovectors for biomedical applications in therapeutics and diagnosticsExplores the future of extracellular vesicle research, including emerging technologies for extracellular vesicle manipulation, novel bioengineering approaches, and the potential of extracellular vesicles in personalized medicine