Statistics for Biology and Health – serie
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141 produkter
Survival Analysis
A Self-Learning Text, Third Edition
Av David G. Kleinbaum, Mitchel Klein
Häftad, 2016
895 kr
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This greatly expanded third edition of Survival Analysis- A Self-learning Text provides a highly readable description of state-of-the-art methods of analysis of survival/event-history data. This text is suitable for researchers and statisticians working in the medical and other life sciences as …
Likelihood and Bayesian Inference
With Applications in Biology and Medicine
Av Leonhard Held, Daniel Sabanés Bové
Häftad, 2021
638 kr
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This richly illustrated textbook covers modern statistical methods with applications in medicine, epidemiology and biology. Firstly, it discusses the importance of statistical models in applied quantitative research and the central role of the likelihood function, describing likelihood-based …
Clinical Prediction Models
A Practical Approach to Development, Validation, and Updating
Inbunden, 2019
1114 kr
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The second edition of this volume provides insight and practical illustrations on how modern statistical concepts and regression methods can be applied in medical prediction problems, including diagnostic and prognostic outcomes. Many advances have been made in statistical approaches towards …
Survival and Event History Analysis
A Process Point of View
Av Odd Aalen, Ornulf Borgan m. fl.
Inbunden, 2008
2319 kr
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The aim of this book is to bridge the gap between standard textbook models and a range of models where the dynamic structure of the data manifests itself fully. The common denominator of such models is stochastic processes. The authors show how counting processes, martingales, and stochastic …
Likelihood and Bayesian Inference
With Applications in Biology and Medicine
Av Leonhard Held, Daniel Sabanés Bové
Inbunden, 2020
893 kr
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This richly illustrated textbook covers modern statistical methods with applications in medicine, epidemiology and biology. Firstly, it discusses the importance of statistical models in applied quantitative research and the central role of the likelihood function, describing likelihood-based …
Regression Methods in Biostatistics
Linear, Logistic, Survival, and Repeated Measures Models
Av Eric Vittinghoff, David V. Glidden m. fl.
Inbunden, 2011
4,0 utav 5 stjärnor. Totalt antal röster: (1)
1225 kr
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This new book provides a unified, in-depth, readable introduction to the multipredictor regression methods most widely used in biostatistics: linear models for continuous outcomes, logistic models for binary outcomes, the Cox model for right-censored survival times, repeated-measures models for …
Bioinformatics and Computational Biology Solutions Using R and Bioconductor
Av Robert Gentleman, Vincent Carey m. fl.
Inbunden, 2005
2366 kr
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Bioconductor is a widely used open source and open development software project for the analysis and comprehension of data arising from high-throughput experimentation in genomics and molecular biology. Bioconductor is rooted in the open source statistical computing environment R.This volume's …
Regression Methods in Biostatistics
Linear, Logistic, Survival, and Repeated Measures Models
Av Eric Vittinghoff, David V. Glidden m. fl.
Häftad, 2014
1114 kr
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This new book provides a unified, in-depth, readable introduction to the multipredictor regression methods most widely used in biostatistics: linear models for continuous outcomes, logistic models for binary outcomes, the Cox model for right-censored survival times, repeated-measures models for …
Applied Multivariate Statistics with R
Häftad, 2024
5,0 utav 5 stjärnor. Totalt antal röster: (1)
918 kr
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Now in its second edition, this book brings multivariate statistics to graduate-level practitioners, making these analytical methods accessible without lengthy mathematical derivations. Using the open source shareware program R, Dr. Zelterman demonstrates the process and outcomes for a wide array …
Design and Analysis of DNA Microarray Investigations
Av Richard M. Simon, Edward L. Korn m. fl.
Inbunden, 2004
1079 kr
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DNA microarrays are an important technology for studying gene expression. With a single hybridization, the level of expression of thousands of genes, or even an entire genome, can be estimated for a sample of cells. Consequently, manylaboratoriesareattemptingtoutilizeDNAmicroarraysintheirresearch. …
Multiple Analyses in Clinical Trials
Fundamentals for Investigators
Inbunden, 2003
559 kr
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One of the most challenging issues for clinical trial investigators, sponsors, and regulatory officials is the interpretation of experimental results that are composed of the results of multiple statistical analyses. These analyses may include the effect of therapy on multiple endpoints, the …
Dynamic Regression Models for Survival Data
Av Torben Martinussen, Thomas H. Scheike
Inbunden, 2006
1616 kr
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In survival analysis there has long been a need for models that goes beyond the Cox model as the proportional hazards assumption often fails in practice. This book studies and applies modern flexible regression models for survival data with a special focus on extensions of the Cox model and …
Evaluation of Surrogate Endpoints
Av Tomasz Burzykowski, Geert Molenberghs m. fl.
Inbunden, 2005
1723 kr
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Both humanitarian and commercial considerations have spurred intensive search for methods to reduce the time and cost required to develop new therapies. The identification and use of surrogate endpoints, i.e., measures that can replace or supplement other endpoints in evaluations of experimental …
Statistical Genetics of Quantitative Traits
Linkage, Maps and QTL
Av Rongling Wu, Changxing Ma m. fl.
Inbunden, 2007
2152 kr
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Most traits in nature and of importance to agriculture are quantitatively inherited. These traits are di?cult to study due to the complex nature of their inheritance. However, recent developments of genomic technologies provide a revolutionary means for unraveling the secrets of genetic variation …
Statistical Methods in Molecular Evolution
Inbunden, 2005
2474 kr
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In the field of molecular evolution, inferences about past evolutionary events are made using molecular data from currently living species. With the availability of genomic data from multiple related species, molecular evolution has become one of the most active and fastest growing fields of study …
Applied Mathematical Demography
Av Nathan Keyfitz, Hal Caswell
Inbunden, 2005
1508 kr
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This third edtion contains new chapters on Matrix Population Models.
Proportional Hazards Regression
Inbunden, 2008
1079 kr
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Proportional hazards models and their extensions (models with ti- dependent covariates, models with time dependent regression co- cients, models with random coe?cients and any mixture of these) can be used to characterize just about any applied problem to which the techniques of survival analysis …
Dose Finding in Drug Development
Av Naitee Ting
Inbunden, 2006
1830 kr
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This book emphasizes dose selection issues from a statistical point of view. It presentsstatisticalapplicationsinthedesignandanalysisofdose–responsestudies. The importance of this subject can be found from the International Conference on Harmonization (ICH) E4 Guidance document. Establishing the …
Statistical Monitoring of Clinical Trials
A Unified Approach
Av Michael A. Proschan, K. K. Gordon Lan m. fl.
Inbunden, 2006
5,0 utav 5 stjärnor. Totalt antal röster: (1)
1553 kr
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The approach taken in this book is to studies monitored over time, what the Central Limit Theorem is to studies with only one analysis. Just as the Central Limit Theorem shows that test statistics involving very different types of clinical trial outcomes are asymptotically normal, this book shows …
Statistical Analysis of Interval-censored Failure Time Data
Av Jianguo Sun
Inbunden, 2006
1937 kr
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Survival analysis, the analysis of failure time data, is a rapid developing area and a number of books on the topic have been published in last twenty-five years. However, all of these books deal with right-censored failure time data, not the analysis of interval-censored failure time data. …
Statistical Methods in Bioinformatics
An Introduction
Av Warren J. Ewens, Gregory R. Grant
Inbunden, 2004
1401 kr
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Advances in computers and biotechnology have had a profound impact on biomedical research, and as a result complex data sets can now be generated to address extremely complex biological questions. Correspondingly, advances in the statistical methods necessary to analyze such data are following …
Design and Analysis of Vaccine Studies
Av M. Elizabeth Halloran, Ira M. Longini, Jr. m. fl.
Inbunden, 2009
2216 kr
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This mongraph will be a reference for statisticians and epidemiologists involved in vaccine studies. It will also be of interest to policy makers in public health who will get a background in this area from the non-technical sections.
Analyzing Ecological Data
Av Alain Zuur, Elena N. Ieno m. fl.
Inbunden, 2007
3010 kr
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'Which test should I apply?' During the many years of working with ecologists, biologists and other environmental scientists, this is probably the question that the authors of this book hear the most often. The answer is always the same and along the lines of 'What are your underlying questions?', …
Statistics of Gene Mapping
Av David Siegmund, Benjamin Yakir
Inbunden, 2007
1664 kr
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Gene mapping is used in experimental genetics to improve the hardiness or productivity of animals or plants of agricultural value, to explore basic mechanisms of inheritance, or to study animal models of human inheritance. In human populations it is used as a first step to identify genes associated …
Statistical Analysis of Recurrent Events
Av Richard J. Cook, Jerald Lawless
Inbunden, 2007
1774 kr
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Recurrent event data arise in diverse fields such as medicine, public health, insurance, social science, economics, manufacturing and reliability. The purpose of this book is to present models and statistical methods for the analysis of recurrent event data. No single comprehensive treatment of …
Frailty Model
Av Luc Duchateau, Paul Janssen
Inbunden, 2007
1079 kr
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Clustered survival data are encountered in many scientific disciplines including human and veterinary medicine, biology, epidemiology, public health and demography. Frailty models provide a powerful tool to analyse clustered survival data. In contrast to the large number of research publications on …
Statistical Analysis of Functional MRI Data
Av Nicole Lazar
Inbunden, 2008
1112 kr
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The study of brain function is one of the most fascinating pursuits of m- ern science. Functional neuroimaging is an important component of much of the current research in cognitive, clinical, and social psychology. The exci- ment of studying the brain is recognized in both the popular press and …
Cancer Mortality and Morbidity Patterns in the U.S. Population
An Interdisciplinary Approach
Av K.G. Manton, Igor Akushevich m. fl.
Inbunden, 2008
1112 kr
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The purpose of this book is to examine the etiology of cancer in large human populations using mathematical models developed from an inter-disciplinary perspective of the population epidemiological, biodemographic, genetic and physiological basis of the mechanisms of cancer initiation and …
Mixed Effects Models and Extensions in Ecology with R
Av Alain Zuur, Elena N. Ieno m. fl.
Inbunden, 2009
1616 kr
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Building on the successful Analysing Ecological Data (2007) by Zuur, Ieno and Smith, the authors now provide an expanded introduction to using regression and its extensions in analysing ecological data. As with the earlier book, real data sets from postgraduate ecological studies or research …
Guide to QTL Mapping with R/qtl
Inbunden, 2009
2474 kr
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Quantitative trait locus (QTL) mapping is used to discover the genetic and molecular architecture underlying complex quantitative traits. It has important applications in agricultural, evolutionary, and biomedical research. R/qtl is an extensible, interactive environment for QTL mapping in …
