Advances in Neuroethics – serie

The volume offers a unique collection of articles on pediatric neuroenhancement from an international and multidisciplinary perspective. In recent years, the topic of “neuroenhancement” has become increasingly relevant in academia and practice, as well as among the public. While autonomous adults are free to choose neuroenhancement, in children it presents its own ethical, social, legal, and developmental issues. A plethora of potential (neurotechnological) enhancement agents are on the market. While the manifold issues surrounding the topic have been extensively discussed, there is little work on the specific questions that arise in children and adolescents. This book addresses this gap in the literature: Next to conceptual and normative work on autonomy and self-control, the collection explores the implications for parenting and schooling, and provides input for a discussion of public attitudes. It is a valuable resource for the different academic communities confronted with questions of how to evaluate and approach enhancement in children and is of interest to neuroethicists, scholars in applied ethics and neurology, psychiatrists and psychologists as well as scientists developing enhancement interventions for children.

Understanding and improving how organizations work and are managed is the object of management research and practice, and this topic is of longstanding interest in the academia and in society at large. More recently, the contribution that the study of the brain could make to, notably, our understanding of decisions, emotional reactions, and behaviors has led to the emergence of the field of “organizational neuroscience”. Within the field of management, organizational neuroscience seeks to explore linkages between neuroscience research, theories, and methods and management research. Its primary goal is to incorporate findings on the cognitive processes underlying the thoughts, behaviors and attitudes of organizational actors in order to better inform management theories, and to assist in understanding, predicting and improving these behaviors in the workplace. As a result, we have seen in the last decade a flurry of research projects and publications in organizational neuroscience, as well as novel or rejuvenated innovations around neuromarketing, neuroleadership, and cognitive enhancement in the work place, to name a few. However, research and practical applications in organizational neuroscience pose profound ethical challenges about, for example, organizational responsibility in the responsible use of scientific innovation. Drawing on recent debates in the field, and in response to upcoming ethical challenges of organization neuroscience, this book introduces “organizational neuroethics” as an emerging interdisciplinary field that addresses the ethics of organizational neuroscience research and applications, as well as the neuroscience of organizational ethics. The first part focuses on the ethics of organizational neuroscience and several chapters tackle the ethics of neuromarketing or neuroleadership and discuss the ethical issues associated with neuroenhancement practice in the workplace. The second part of the book addresses cutting-edge topics in the neuroscience of organizational ethics.Written by international experts in the fields of management, neuroscience, ethics, and social science, this book will be of prime interest to practitioners, researchers and students in the various fields concerned with improving management research and practices, as well as organizational ethics.

Understanding and improving how organizations work and are managed is the object of management research and practice, and this topic is of longstanding interest in the academia and in society at large. More recently, the contribution that the study of the brain could make to, notably, our understanding of decisions, emotional reactions, and behaviors has led to the emergence of the field of “organizational neuroscience”. Within the field of management, organizational neuroscience seeks to explore linkages between neuroscience research, theories, and methods and management research. Its primary goal is to incorporate findings on the cognitive processes underlying the thoughts, behaviors and attitudes of organizational actors in order to better inform management theories, and to assist in understanding, predicting and improving these behaviors in the workplace. As a result, we have seen in the last decade a flurry of research projects and publications in organizational neuroscience, as well as novel or rejuvenated innovations around neuromarketing, neuroleadership, and cognitive enhancement in the work place, to name a few. However, research and practical applications in organizational neuroscience pose profound ethical challenges about, for example, organizational responsibility in the responsible use of scientific innovation. Drawing on recent debates in the field, and in response to upcoming ethical challenges of organization neuroscience, this book introduces “organizational neuroethics” as an emerging interdisciplinary field that addresses the ethics of organizational neuroscience research and applications, as well as the neuroscience of organizational ethics. The first part focuses on the ethics of organizational neuroscience and several chapters tackle the ethics of neuromarketing or neuroleadership and discuss the ethical issues associated with neuroenhancement practice in the workplace. The second part of the book addresses cutting-edge topics in the neuroscience of organizational ethics.Written by international experts in the fields of management, neuroscience, ethics, and social science, this book will be of prime interest to practitioners, researchers and students in the various fields concerned with improving management research and practices, as well as organizational ethics.

This edited volume represents a unique addition to the available literature on animal ethics, animal studies, and neuroethics. Its goal is to expand discussions on animal ethics and neuroethics by weaving together different threads: philosophy of mind and animal minds, neuroscientific study of animal minds, and animal ethics.Neuroethical questions concerning animals’ moral status, animal minds and consciousness, animal pain, and the adequacy of animal models for neuropsychiatric disease have long been topics of debate in philosophy and ethics, and more recently also in neuroscientific research. The book presents a transdisciplinary blend of voices, underscoring different perspectives on the broad questions of how neuroscience can contribute to our understanding of nonhuman minds, and on debates over the moral status of nonhuman animals. All chapters were written by outstanding scholars in philosophy, neuroscience, animal behavior, biology, neuroethics, and bioethics, and cover a range of issues and species/taxa.Given its scope, the book will appeal to scientists and students interested in the debate on animal ethics, while also offering an important resource for future researchers. Chapter 13 is available open access under a CC BY 4.0 license at link.springer.com.

This edited volume represents a unique addition to the available literature on animal ethics, animal studies, and neuroethics. Its goal is to expand discussions on animal ethics and neuroethics by weaving together different threads: philosophy of mind and animal minds, neuroscientific study of animal minds, and animal ethics.Neuroethical questions concerning animals’ moral status, animal minds and consciousness, animal pain, and the adequacy of animal models for neuropsychiatric disease have long been topics of debate in philosophy and ethics, and more recently also in neuroscientific research. The book presents a transdisciplinary blend of voices, underscoring different perspectives on the broad questions of how neuroscience can contribute to our understanding of nonhuman minds, and on debates over the moral status of nonhuman animals. All chapters were written by outstanding scholars in philosophy, neuroscience, animal behavior, biology, neuroethics, and bioethics, and cover a range of issues and species/taxa.Given its scope, the book will appeal to scientists and students interested in the debate on animal ethics, while also offering an important resource for future researchers. Chapter 13 is available open access under a CC BY 4.0 license at link.springer.com.

This book addresses current issues in the neuroscience and ethics of dementia care, including philosophical as well as ethical legal, and social issues (ELSIs), issues in clinical, institutional, and private care-giving, and international perspectives on dementia and care innovations. As such, it is a must-read for anyone interested in a well-researched, thought-provoking overview of current issues in dementia diagnosis, care, and social and legal policy. All contributions reflect the latest neuroscientific research on dementia, either broadly construed or in terms of the etiologies and symptoms of particular forms of dementia. Given its interdisciplinary and international scope, its depth of research, and its qualitative emphasis, the book represents a valuable addition to the available literature on neuroethics, gerontology, and neuroscientific memory research.

This book addresses current issues in the neuroscience and ethics of dementia care, including philosophical as well as ethical legal, and social issues (ELSIs), issues in clinical, institutional, and private care-giving, and international perspectives on dementia and care innovations. As such, it is a must-read for anyone interested in a well-researched, thought-provoking overview of current issues in dementia diagnosis, care, and social and legal policy. All contributions reflect the latest neuroscientific research on dementia, either broadly construed or in terms of the etiologies and symptoms of particular forms of dementia. Given its interdisciplinary and international scope, its depth of research, and its qualitative emphasis, the book represents a valuable addition to the available literature on neuroethics, gerontology, and neuroscientific memory research.

Neurotechnologies such as brain-computer interfaces (BCIs), which allow technical devices to be used with the power of thought or concentration alone, are no longer a futuristic dream or, depending on the viewpoint, a nightmare. Moreover, the combination of neurotechnologies and AI raises a host of pressing problems. Now that these technologies are about to leave the laboratory and enter the real world, these problems and implications can and should be scrutinized.This volume brings together scholars from a wide range of academic disciplines such as philosophy, law, the social sciences and neurosciences, and is unique in terms of both its focus and its methods. The latter vary considerably, and range from philosophical analysis and phenomenologically inspired descriptions to legal analysis and socio-empirical research. This diversified approach allows the book to explore the entire spectrum of philosophical, normative, legal and empirical dimensions of intelligent neurotechnologies.  Philosophical and legal analyses of normative problems are complemented by a thorough empirical assessment of how BCIs and other forms of neurotechnology are being implemented, and what their measurable implications are. To take a closer look at specific neurotechnologies, a number of applications are addressed. Case studies, previously unidentified issues, and normative insights on these cases complement the rich portrait this volume provides.  Clinicians, philosophers, lawyers, social scientists and engineers will greatly benefit from the collection of articles compiled in this book, which will likely become a standard reference work on the philosophy of intelligent neurotechnologies.

Neurotechnologies such as brain-computer interfaces (BCIs), which allow technical devices to be used with the power of thought or concentration alone, are no longer a futuristic dream or, depending on the viewpoint, a nightmare. Moreover, the combination of neurotechnologies and AI raises a host of pressing problems. Now that these technologies are about to leave the laboratory and enter the real world, these problems and implications can and should be scrutinized.This volume brings together scholars from a wide range of academic disciplines such as philosophy, law, the social sciences and neurosciences, and is unique in terms of both its focus and its methods. The latter vary considerably, and range from philosophical analysis and phenomenologically inspired descriptions to legal analysis and socio-empirical research. This diversified approach allows the book to explore the entire spectrum of philosophical, normative, legal and empirical dimensions of intelligent neurotechnologies.  Philosophical and legal analyses of normative problems are complemented by a thorough empirical assessment of how BCIs and other forms of neurotechnology are being implemented, and what their measurable implications are. To take a closer look at specific neurotechnologies, a number of applications are addressed. Case studies, previously unidentified issues, and normative insights on these cases complement the rich portrait this volume provides.  Clinicians, philosophers, lawyers, social scientists and engineers will greatly benefit from the collection of articles compiled in this book, which will likely become a standard reference work on the philosophy of intelligent neurotechnologies.

This volume provides an interdisciplinary collection of essays from leaders in various fields addressing the current and future challenges arising from the implementation of AI in brain and mental health. Artificial Intelligence (AI) has the potential to transform health care and improve biomedical research. While the potential of AI in brain and mental health is tremendous, its ethical, regulatory and social impacts have not been assessed in a comprehensive and systemic way.The volume is structured according to three main sections, each of them focusing on different types of AI technologies. Part 1, Big Data and Automated Learning: Scientific and Ethical Considerations, specifically addresses issues arising from the use of AI software, especially machine learning, in the clinical context or for therapeutic applications. Part 2, AI for Digital Mental Health and Assistive Robotics: Philosophical and Regulatory Challenges, examines philosophical, ethical and regulatory issues arising from the use of an array of technologies beyond the clinical context. In the final section of the volume, Part 3 entitled AI in Neuroscience and Neurotechnology: Ethical, Social and Policy Issues, contributions examine some of the implications of AI in neuroscience and neurotechnology and the regulatory gaps or ambiguities that could potentially hamper the responsible development and implementation of AI solutions in brain and mental health. In light of its comprehensiveness and multi-disciplinary character, this book marks an important milestone in the public understanding of the ethics of AI in brain and mental health and provides a useful resource for any future investigation in this crucial and rapidly evolving area of AI application.The book is of interest to a wide audience in neuroethics, robotics, computer science, neuroscience, psychiatry and mental health.

This volume provides an interdisciplinary collection of essays from leaders in various fields addressing the current and future challenges arising from the implementation of AI in brain and mental health. Artificial Intelligence (AI) has the potential to transform health care and improve biomedical research. While the potential of AI in brain and mental health is tremendous, its ethical, regulatory and social impacts have not been assessed in a comprehensive and systemic way.The volume is structured according to three main sections, each of them focusing on different types of AI technologies. Part 1, Big Data and Automated Learning: Scientific and Ethical Considerations, specifically addresses issues arising from the use of AI software, especially machine learning, in the clinical context or for therapeutic applications. Part 2, AI for Digital Mental Health and Assistive Robotics: Philosophical and Regulatory Challenges, examines philosophical, ethical and regulatory issues arising from the use of an array of technologies beyond the clinical context. In the final section of the volume, Part 3 entitled AI in Neuroscience and Neurotechnology: Ethical, Social and Policy Issues, contributions examine some of the implications of AI in neuroscience and neurotechnology and the regulatory gaps or ambiguities that could potentially hamper the responsible development and implementation of AI solutions in brain and mental health. In light of its comprehensiveness and multi-disciplinary character, this book marks an important milestone in the public understanding of the ethics of AI in brain and mental health and provides a useful resource for any future investigation in this crucial and rapidly evolving area of AI application.The book is of interest to a wide audience in neuroethics, robotics, computer science, neuroscience, psychiatry and mental health.

This volume elucidates the pivotal ethical and legal issues arising from the use of brain organoids for research, therapeutic and enhancement purposes.The function of the human brain is still a mystery. Until recently, only post-mortem tissue was available for a structural examination of the brain. Consequently, the examination results could only reflect the state at the end of life. However, in order to better understand the development and function of the human brain, dynamic and functional investigations of different human brain cells are necessary. This is where brain organoids, artificially grown in vitro miniature brains, provide the opportunity for more flexible research scenarios.At the same time, however, the use of brain organoids in research and therapy raises the question of how these new entities are to be treated from an ethical and legal point of view. Against this background, this volume aims at clarifying the normative implications of the use of brain organoids in research and therapy.  The ethical reflections on the status of brain organoids, informed consent, human-to-animal chimeras and neuro-enhancement are mirrored by corresponding legal analyses. The ethical and legal assessments are preceded by an introduction to the scientific and medical background of the brain organoid technology. A final chapter will be devoted to the issue of whether international harmonization of normative standards for brain organoid research and therapy is feasible and advisable.

This volume elucidates the pivotal ethical and legal issues arising from the use of brain organoids for research, therapeutic and enhancement purposes.The function of the human brain is still a mystery. Until recently, only post-mortem tissue was available for a structural examination of the brain. Consequently, the examination results could only reflect the state at the end of life. However, in order to better understand the development and function of the human brain, dynamic and functional investigations of different human brain cells are necessary. This is where brain organoids, artificially grown in vitro miniature brains, provide the opportunity for more flexible research scenarios.At the same time, however, the use of brain organoids in research and therapy raises the question of how these new entities are to be treated from an ethical and legal point of view. Against this background, this volume aims at clarifying the normative implications of the use of brain organoids in research and therapy.  The ethical reflections on the status of brain organoids, informed consent, human-to-animal chimeras and neuro-enhancement are mirrored by corresponding legal analyses. The ethical and legal assessments are preceded by an introduction to the scientific and medical background of the brain organoid technology. A final chapter will be devoted to the issue of whether international harmonization of normative standards for brain organoid research and therapy is feasible and advisable.

This book presents principal controversies over the determination of death by neurologic criteria (“brain death”). The editors and authors are exceedingly well-versed in this subject and are on the forefront of the current debates. The content is divided in the following disciplinary: philosophical (conceptual), medical, scientific, legal, religious, and ethical/social. Many of the topics feature pro-con debates, allowing readers to consider the merits of the arguments and decide their own position. The work is targeted to clinicians and nurses who treat critically ill and dying patients, organ donation personnel, ethicists and philosophers who write on end-of-life issues, and lawyers and legislative/public policy professionals who draft laws on death determination. It identifies and debates the essential controversies currently raging in academic and public policy circles over the medical adequacy, scientific validity, and conceptual coherence of death determination by neurologic criteria. Whether a professional or a student, the reader will be given a comprehensive course in the most pressing controversies and areas of consensus in the determination of death by neurologic criteria.

This book presents principal controversies over the determination of death by neurologic criteria (“brain death”). The editors and authors are exceedingly well-versed in this subject and are on the forefront of the current debates. The content is divided in the following disciplinary: philosophical (conceptual), medical, scientific, legal, religious, and ethical/social. Many of the topics feature pro-con debates, allowing readers to consider the merits of the arguments and decide their own position. The work is targeted to clinicians and nurses who treat critically ill and dying patients, organ donation personnel, ethicists and philosophers who write on end-of-life issues, and lawyers and legislative/public policy professionals who draft laws on death determination. It identifies and debates the essential controversies currently raging in academic and public policy circles over the medical adequacy, scientific validity, and conceptual coherence of death determination by neurologic criteria. Whether a professional or a student, the reader will be given a comprehensive course in the most pressing controversies and areas of consensus in the determination of death by neurologic criteria.

In this volume the authors explore the landscape of thought on the ethical and policy implications of Brain Computer Interface (BCI) technology. BCI technology is a promising and rapidly advancing research area. Recent developments in the technology, based on animal and human studies, allow for the restoration and potential augmentation of faculties of perception and physical movement, and even the transfer of information between brains. Brain activity can be interpreted through both invasive and non-invasive monitoring devices, allowing for novel, therapeutic solutions for individuals with disabilities and for other non-medical applications. However, a number of ethical and policy issues have been identified from the use of BCI technology, with the potential for near-future advancements in the technology to raise unique new ethical and policy questions that society has never grappled with before. The volume has three parts: 1) Past, Present and Future of BCI technology, 2) Ethical and Philosophical Issues and 3) Legal and Policy Implications. The rich and detailed picture of the field of BCI ethics with contributors from various fields and backgrounds, from academia and from the commercial sphere may serve as an introductory textbook into the neuroethics of BCI, or as a resource for neuroscientists, engineers, and medical practitioners to gain additional insight into the ethical and policy implications of their work.

In this volume the authors explore the landscape of thought on the ethical and policy implications of Brain Computer Interface (BCI) technology. BCI technology is a promising and rapidly advancing research area. Recent developments in the technology, based on animal and human studies, allow for the restoration and potential augmentation of faculties of perception and physical movement, and even the transfer of information between brains. Brain activity can be interpreted through both invasive and non-invasive monitoring devices, allowing for novel, therapeutic solutions for individuals with disabilities and for other non-medical applications. However, a number of ethical and policy issues have been identified from the use of BCI technology, with the potential for near-future advancements in the technology to raise unique new ethical and policy questions that society has never grappled with before. The volume has three parts: 1) Past, Present and Future of BCI technology, 2) Ethical and Philosophical Issues and 3) Legal and Policy Implications. The rich and detailed picture of the field of BCI ethics with contributors from various fields and backgrounds, from academia and from the commercial sphere may serve as an introductory textbook into the neuroethics of BCI, or as a resource for neuroscientists, engineers, and medical practitioners to gain additional insight into the ethical and policy implications of their work.

As transcranial magnetic stimulation (TMS) continues to expand from a tool of neuroscience research into a growing array of clinical applications, it presents a number of open questions that both invite and complicate ethical evaluation. Empirically supported concerns remain regarding interactions between TMS and psychiatric medications or other interventions, the potential for adverse effects in stimulated brain regions, and whether modulation of brain activity—particularly via changes in oscillatory states—might affect aspects of personhood.This volume explores the ethical landscape surrounding TMS in both research and clinical settings. Prior neuroethics literature has largely focused on theoretical implications of neurostimulation technologies, including conceptual clarification (e.g., invasiveness) and normative questions regarding the alignment of these technologies with societal values. However, while some empirical work has captured perspectives from TMS patients, many key voices—such as those of family members, clinicians, and underrepresented communities—have remained absent from scholarly discussions.Spanning historical reflection, theoretical debate, empirical analysis, and clinical insight, this collection features contributions from scholars and practitioners working at the intersection of neuroethics, neuroscience, psychiatry, and biomedical engineering. Part I of the volume offers historical and theoretical reflections, including the origins and growth of TMS research, racial disparities in access and participation, caregiver perspectives, and emerging issues related to cognitive enhancement, non-clinical use, and applications in social neuroscience and creativity. Part II turns to new directions and ethical issues in clinical TMS research, addressing treatment subgrouping, adolescent and geriatric use, mood and substance use disorders, suicidality, and the evolving regulatory landscape.Together, these chapters provide an interdisciplinary examination of the ethical, clinical, and societal dimensions of TMS. Whether as an introduction to the neuroethics of brain stimulation or as a resource for neuroscientists, clinicians, engineers, and ethicists, this volume aims to foster greater understanding and dialogue around the responsible development and application of TMS.

As transcranial magnetic stimulation (TMS) continues to expand from a tool of neuroscience research into a growing array of clinical applications, it presents a number of open questions that both invite and complicate ethical evaluation. Empirically supported concerns remain regarding interactions between TMS and psychiatric medications or other interventions, the potential for adverse effects in stimulated brain regions, and whether modulation of brain activity—particularly via changes in oscillatory states—might affect aspects of personhood.This volume explores the ethical landscape surrounding TMS in both research and clinical settings. Prior neuroethics literature has largely focused on theoretical implications of neurostimulation technologies, including conceptual clarification (e.g., invasiveness) and normative questions regarding the alignment of these technologies with societal values. However, while some empirical work has captured perspectives from TMS patients, many key voices—such as those of family members, clinicians, and underrepresented communities—have remained absent from scholarly discussions.Spanning historical reflection, theoretical debate, empirical analysis, and clinical insight, this collection features contributions from scholars and practitioners working at the intersection of neuroethics, neuroscience, psychiatry, and biomedical engineering. Part I of the volume offers historical and theoretical reflections, including the origins and growth of TMS research, racial disparities in access and participation, caregiver perspectives, and emerging issues related to cognitive enhancement, non-clinical use, and applications in social neuroscience and creativity. Part II turns to new directions and ethical issues in clinical TMS research, addressing treatment subgrouping, adolescent and geriatric use, mood and substance use disorders, suicidality, and the evolving regulatory landscape.Together, these chapters provide an interdisciplinary examination of the ethical, clinical, and societal dimensions of TMS. Whether as an introduction to the neuroethics of brain stimulation or as a resource for neuroscientists, clinicians, engineers, and ethicists, this volume aims to foster greater understanding and dialogue around the responsible development and application of TMS.

In the tradition of moral philosophy, long dominated by a rationalist paradigm, the idea of moral intuition has often been a source of embarrassment. How can the mind form a moral judgment within seconds, without any apparent reasoning?In the spirit of neuroethics, this book demystifies moral intuition by examining the mental and neural processes that generate such automatic evaluations. Addressed to specialists in philosophy, psychology, and AI ethics, the book systematically investigates three questions: how moral intuitions work, how they can improve, and how they can be implemented in artificial agents.Challenging the dominant default-interventionist view of moral reasoning, the first part argues that moral intuitions play a dual role: they detect harm and help in the environment, and they metacognitively regulate the deployment of cognitive resources, triggering reflection when intuitive outputs are uncertain or conflicting. Building on this foundation, the book offers a dyadic classification of the cognitive biases that shape moral intuitions and critically assesses strategies for mitigating them, including reasoning, expertise, and nudging. The final part extends this moral-psychological framework to artificial intelligence, arguing that the implementation of moral intuitions in artificial agents is both a feasible and a philosophically defensible goal, compatible with the functional capacities of contemporary AI systems.In doing so, the book sets a new research agenda for understanding, improving, and implementing moral intuitions in both human and artificial agents.

This is the first book entirely dedicated to exploring issues associated with the nature of neuroethics. It reflects on some of the underlying assumptions in neuroethics, and the implications of those assumptions with respect to training and education programs, research activities, policy engagement, public discourse, teaching, ethics consultation and mentoring, to name but a few areas of interest.  Internationally respected and emerging leaders in the area have taken up the pen to express and debate their views about the development, focus and future of neuroethics. They share their analyses and make recommendations regarding how neuroscience could more effectively explore and tackle its philosophical, ethical, and societal implications.